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UY36221A - Derivados de isoindolinona - Google Patents

Derivados de isoindolinona

Info

Publication number
UY36221A
UY36221A UY0001036221A UY36221A UY36221A UY 36221 A UY36221 A UY 36221A UY 0001036221 A UY0001036221 A UY 0001036221A UY 36221 A UY36221 A UY 36221A UY 36221 A UY36221 A UY 36221A
Authority
UY
Uruguay
Prior art keywords
isoindolinone derivatives
isoindolinone
derivatives
compounds
compositions
Prior art date
Application number
UY0001036221A
Other languages
English (en)
Inventor
Brian Alvin Johns
Emile Johann Velthuisen
Jason Gordon Weatherhead
Original Assignee
Viiv Healthcare Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viiv Healthcare Uk Ltd filed Critical Viiv Healthcare Uk Ltd
Publication of UY36221A publication Critical patent/UY36221A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035Isoindoles, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se dan a conocer compuestos de la fórmula I y métodos para el tratamiento de infecciones virales con composiciones que comprenden estos compuestos.
UY0001036221A 2014-07-22 2015-07-20 Derivados de isoindolinona UY36221A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462027359P 2014-07-22 2014-07-22

Publications (1)

Publication Number Publication Date
UY36221A true UY36221A (es) 2016-02-29

Family

ID=53718075

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001036221A UY36221A (es) 2014-07-22 2015-07-20 Derivados de isoindolinona

Country Status (17)

Country Link
US (1) US10118894B2 (es)
EP (1) EP3172200B1 (es)
JP (1) JP2017521458A (es)
KR (1) KR20170032338A (es)
CN (1) CN106536513A (es)
AR (1) AR101255A1 (es)
AU (1) AU2015293506B2 (es)
CA (1) CA2954733A1 (es)
CL (1) CL2017000152A1 (es)
ES (1) ES2703352T3 (es)
IL (1) IL249581A0 (es)
PT (1) PT3172200T (es)
RU (1) RU2017103656A (es)
TW (1) TW201617315A (es)
UY (1) UY36221A (es)
WO (1) WO2016012930A1 (es)
ZA (1) ZA201608511B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6579549B2 (ja) 2014-05-16 2019-09-25 塩野義製薬株式会社 Hiv複製阻害作用を有する3環性複素環誘導体
EP3305789A4 (en) 2015-05-29 2018-11-21 Shionogi & Co., Ltd. Nitrogen-containing tricyclic derivative having hiv replication inhibitory activity
WO2018020357A1 (en) 2016-07-25 2018-02-01 Viiv Healthcare Uk Limited Indoline derivatives
WO2020102198A1 (en) 2018-11-13 2020-05-22 Incyte Corporation Heterocyclic derivatives as pi3k inhibitors
US11396502B2 (en) 2018-11-13 2022-07-26 Incyte Corporation Substituted heterocyclic derivatives as PI3K inhibitors
US11161838B2 (en) 2018-11-13 2021-11-02 Incyte Corporation Heterocyclic derivatives as PI3K inhibitors
EP4301407A4 (en) * 2021-03-03 2025-02-12 Univ Missouri SUPPRESSION OF COVID-19 REPLICATION BY COVID-19 ENTRY INHIBITORS
CN115160211B (zh) * 2022-06-23 2023-11-03 温州大学 一种异吲哚啉酮类化合物的绿色合成方法
KR20240049492A (ko) 2022-10-08 2024-04-16 임서윤 문어발 건조대

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009026248A2 (en) * 2007-08-17 2009-02-26 The Government Of The United States, As Represented By The Secretary Of Health And Human Services, National Institutes Of Health, Office Of Technology Transfer Hydrazide, amide, phthalimide and phthalhydrazide analogs as inhibitors of retroviral integrase
MX2010005334A (es) 2007-11-16 2010-05-27 Boehringer Ingelheim Int Inhibidores de la replicacion del virus de la inmunodeficiencia humana.
ES2742261T3 (es) * 2011-04-15 2020-02-13 Hivih Inhibidores de la replicación viral, su proceso de preparación y sus usos terapéuticos
WO2013012649A1 (en) 2011-07-15 2013-01-24 Glaxosmithkline Llc Azaindole compounds and methods for treating hiv
WO2013016441A1 (en) * 2011-07-26 2013-01-31 The United States of America, represented by The Secretary, Department of Health & Human Services Hiv integrase inhibitory oxoisoindoline sulfonamides
US9284323B2 (en) * 2012-01-04 2016-03-15 Gilead Sciences, Inc. Naphthalene acetic acid derivatives against HIV infection
US9006235B2 (en) * 2012-03-06 2015-04-14 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
PE20141558A1 (es) * 2012-04-20 2014-11-06 Gilead Sciences Inc Derivados de acido benzotiazol-6-il acetico y su uso para tratar una infeccion por vih
CA2876370A1 (en) * 2012-07-12 2014-01-16 Viiv Healthcare Uk Limited Compounds and methods for treating hiv

Also Published As

Publication number Publication date
IL249581A0 (en) 2017-02-28
AR101255A1 (es) 2016-12-07
PT3172200T (pt) 2019-01-17
CN106536513A (zh) 2017-03-22
RU2017103656A3 (es) 2018-11-07
EP3172200B1 (en) 2018-10-17
TW201617315A (zh) 2016-05-16
CA2954733A1 (en) 2016-01-28
ZA201608511B (en) 2019-06-26
CL2017000152A1 (es) 2017-07-28
US20170204058A1 (en) 2017-07-20
US10118894B2 (en) 2018-11-06
AU2015293506B2 (en) 2017-08-17
ES2703352T3 (es) 2019-03-08
EP3172200A1 (en) 2017-05-31
KR20170032338A (ko) 2017-03-22
RU2017103656A (ru) 2018-08-22
AU2015293506A1 (en) 2017-01-12
WO2016012930A1 (en) 2016-01-28
JP2017521458A (ja) 2017-08-03

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20220705