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UY34504A - Prevention of adverse effects caused by bispecific antibodies EpCAMxCD3 - Google Patents

Prevention of adverse effects caused by bispecific antibodies EpCAMxCD3

Info

Publication number
UY34504A
UY34504A UY0001034504A UY34504A UY34504A UY 34504 A UY34504 A UY 34504A UY 0001034504 A UY0001034504 A UY 0001034504A UY 34504 A UY34504 A UY 34504A UY 34504 A UY34504 A UY 34504A
Authority
UY
Uruguay
Prior art keywords
epcamxcd3
prevention
adverse effects
bispecific antibodies
effects caused
Prior art date
Application number
UY0001034504A
Other languages
Spanish (es)
Inventor
Sabine Kaubitzsch Stienen
Original Assignee
Amgen Res Munich Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Res Munich Gmbh filed Critical Amgen Res Munich Gmbh
Publication of UY34504A publication Critical patent/UY34504A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

No escanear figura.
UY0001034504A 2011-12-09 2012-12-07 Prevention of adverse effects caused by bispecific antibodies EpCAMxCD3 UY34504A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161569180P 2011-12-09 2011-12-09

Publications (1)

Publication Number Publication Date
UY34504A true UY34504A (en) 2013-06-28

Family

ID=47520027

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001034504A UY34504A (en) 2011-12-09 2012-12-07 Prevention of adverse effects caused by bispecific antibodies EpCAMxCD3

Country Status (5)

Country Link
AR (1) AR089114A1 (en)
AU (1) AU2012350429A1 (en)
TW (1) TW201322985A (en)
UY (1) UY34504A (en)
WO (1) WO2013083809A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1874821T3 (en) 2005-04-26 2013-09-30 Trion Pharma Gmbh Combination of antibodies and glucocorticoids for treating cancer
BR112017024757A2 (en) 2015-05-18 2018-11-13 TCR2 Therapeutics Inc. compositions and methods for reprogramming tcr using fusion proteins
US12128102B2 (en) 2016-03-08 2024-10-29 Takeda Pharmaceutical Company Limited Constrained conditionally activated binding proteins
IL302613B1 (en) 2017-09-08 2024-12-01 Maverick Therapeutics Inc Binding proteins are activated under limited conditions
US11685780B2 (en) 2019-03-05 2023-06-27 Takeda Pharmaceutical Company Limited Single domain antigen binding domains that bind human Trop2
WO2023044039A1 (en) * 2021-09-16 2023-03-23 TCR2 Therapeutics Inc. Compositions and methods for treating cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
DE3883899T3 (en) 1987-03-18 1999-04-22 Sb2, Inc., Danville, Calif. CHANGED ANTIBODIES.
AU612370B2 (en) 1987-05-21 1991-07-11 Micromet Ag Targeted multifunctional proteins
WO2004106383A1 (en) 2003-05-31 2004-12-09 Micromet Ag Pharmaceutical composition comprising a bispecific antibody for epcam
US8076459B2 (en) 2003-10-16 2011-12-13 Micromet Ag Multispecfic deimmunized CD3-binders
PL1874821T3 (en) * 2005-04-26 2013-09-30 Trion Pharma Gmbh Combination of antibodies and glucocorticoids for treating cancer
MX2009010611A (en) 2007-04-03 2010-03-26 Micromet Ag Cross-species-specific bispecific binders.
FI2155783T4 (en) 2007-04-03 2022-12-15 Cross-species-specific cd3-epsilon binding domain
RU2547600C2 (en) 2008-10-01 2015-04-10 Эмджен Рисерч (Мьюник) Гмбх Pscaxcd3, cd19xcd3, c-metxcd3, endosialin xcd3, epcamxcd3, igf-1rxcd3 or fap-alpha xcd3 bispecific single-chain antibody with inter-species specificity
MX2012003175A (en) 2009-09-18 2012-04-11 Micromet Ag Dosage regimen for administering an epcamxcd3 bispecific antibody.

Also Published As

Publication number Publication date
AU2012350429A1 (en) 2013-07-11
AR089114A1 (en) 2014-07-30
TW201322985A (en) 2013-06-16
WO2013083809A1 (en) 2013-06-13

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20201020