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Application filed by Boheringer Ingelheim Pharma KgfiledCriticalBoheringer Ingelheim Pharma Kg
Priority to UY26900ApriorityCriticalpatent/UY26900A1/en
Publication of UY26900A1publicationCriticalpatent/UY26900A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen Condensed Heterocyclic Rings
(AREA)
Abstract
La presente invención se refiere a heterociclos bicíclicos de la fórmula general (I) en la que Ra a Rc´ A a E y X están definidos como en la reivindicación 1, a sus tautómeros, sus estereoisómeros y sus sales, en particular sus sales fisiológicamente compatibles con ácidos o bases inorgánicos u orgánicos, que presentan valiosas propiedades farmacológicas, en particular un efecto inhibidor sobre la transducción de senales inducida por tirosino-quinasas, a su empleo para el tratamiento de enfermedades, en particular de enfermedades tumorales, de enfermedades de los pulmones y de las vías respiratorias, y a su preparación.The present invention relates to bicyclic heterocycles of the general formula (I) in which Ra to Rc 'A to E and X are defined as in claim 1, their tautomers, their stereoisomers and their salts, in particular their physiologically salts compatible with inorganic or organic acids or bases, which have valuable pharmacological properties, in particular an inhibitory effect on tyrosine kinase-induced signal transduction, for use in the treatment of diseases, in particular of tumor diseases, of diseases of the lungs and respiratory tract, and its preparation.
UY26900A2001-08-232001-08-23
BICYCLIC HETEROCICLES, DRUGS CONTAINING THESE COMPOUNDS, THEIR EMPLOYMENT AND PROCEDURES FOR THEIR PREPARATION
UY26900A1
(en)