US3901233A - Ear applicator - Google Patents
Ear applicator Download PDFInfo
- Publication number
- US3901233A US3901233A US418815A US41881573A US3901233A US 3901233 A US3901233 A US 3901233A US 418815 A US418815 A US 418815A US 41881573 A US41881573 A US 41881573A US 3901233 A US3901233 A US 3901233A
- Authority
- US
- United States
- Prior art keywords
- applicator
- collar
- ear canal
- ointment
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000000613 ear canal Anatomy 0.000 claims abstract description 30
- 239000007788 liquid Substances 0.000 claims abstract description 22
- 239000002674 ointment Substances 0.000 claims abstract description 22
- 230000001681 protective effect Effects 0.000 claims abstract description 15
- 239000000463 material Substances 0.000 claims abstract description 14
- 229920001296 polysiloxane Polymers 0.000 claims abstract description 14
- 239000000126 substance Substances 0.000 claims abstract description 10
- 230000002745 absorbent Effects 0.000 claims abstract description 6
- 239000002250 absorbent Substances 0.000 claims abstract description 6
- 238000000151 deposition Methods 0.000 claims description 4
- 239000011248 coating agent Substances 0.000 abstract description 8
- 238000000576 coating method Methods 0.000 abstract description 8
- 238000002360 preparation method Methods 0.000 abstract description 3
- 210000002939 cerumen Anatomy 0.000 description 10
- 206010033072 otitis externa Diseases 0.000 description 4
- 239000003221 ear drop Substances 0.000 description 3
- 229940047652 ear drops Drugs 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 239000006196 drop Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000002803 maceration Methods 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 206010050337 Cerumen impaction Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000002788 crimping Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000003811 finger Anatomy 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000012858 resilient material Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000009182 swimming Effects 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F11/00—Methods or devices for treatment of the ears or hearing sense; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand
Definitions
- An applicator including a tubular collapsible body containing a liquid preparation, one end being permanently closed, the other end being initially closed and having means for opening it to provide an outlet orifice.
- a collar made of absorbent spongy material impregnated with a protective substance in ointment form.
- the liquid and ointment are silicone.
- the collar is somewhat larger in diameter than the ear canal and is desirably frusto-conical in outer contour so that it can be inserted into the meatus of the ear and partially into the adjacent portion of the ear canal.
- a slight twisting of applicator causes the collar to deposit a coating of ointment on the skin it contacts, and the user then squeezes the applicator body to force some of the liquid into the ear canal.
- cerumen may well have bactericidal or fungicidal properties which maintain the normal healthy state of the skin of the external ear canal, and loss of cerumen may accordingly increase the incidence of external otitis for this reason also.
- Ear drops particularly of silicone, have been used to provide a coating over the skin of the ear canal and thereby minimize removal of cerumen.
- such drops fall out of the ear fairly soon after application, especially if the user moves his head into a number of positions and orientations, as is typical in swimming.
- the present invention provides means for application of a coating of a protective substance, preferably silicone, in the form of a gel or ointment to the meatus and adjacent portion of the ear canal and, substantially simultaneously, the application of liquid drops to the inner portion of the ear canal.
- a protective substance preferably silicone
- the relatively stronger coating of silicone ointment on those surfaces minimizes loss of cerumen by the action of water, and also tends to inhibit the loss of the liquid ear drops from the inner portion of the ear canal.
- clinical experience tends to indicate that the presence of any foreign substance, e.g. the ointment or gel above mentioned, on the cerumen producing area of the ear canal may actually stimulate the production of cerumen,
- an applicator having a quantity of liquid preparation in a suitable container such as a collapsible tube having an outlet orifice, and a collar of absorbent spongy material surrounds the orifice and is impregnated with a suitable material in ointment or gel form.
- a suitable container such as a collapsible tube having an outlet orifice
- a collar of absorbent spongy material surrounds the orifice and is impregnated with a suitable material in ointment or gel form.
- Other objects are to provide such a device having a container from which liquid can be expelled from an orifice, and a collar of spongy material surrounding the orifice and impregnated with a protective material in ointment form; to provide such a device particularly effective in applying silicone to the ear canal to minimize loss of cerumen; and for other purposes as will be understood from the following description of a preferred embodiment of the invention, taken in conjunction with the appended drawing.
- FIG. I is a side elevational view of an applicator of the present invention, in a package shown in section.
- FIG. 2 is a partially sectional view of the applicator, taken on arrows Ill-11 of FIG. 1.
- FIG. 3 is a fragmentary section view of the outlet end of the applicator with the closure member reinserted after initial use of the device.
- FIG. 4 is a sectional view of the outer portion of the human ear, showing actual use of the applicator.
- FIG. 1 there is shown an applicator in accordance with the present invention as it may be packaged for distribution in a conventional container which serves to prolong shelf life by minimizing drying out of the impregnated collar of the device.
- a container is indicated generally at 10 and includes a base sheet 12 of c ardboard or the like and a cover indicated generally at 14 desirably made of a preferably transparent plastic sheet material of the type used in the conventional blister pack and having a continuous marginal lip 16 attached to base sheet 12 by a suitable adhesive.
- cover 14 and base 12 form a cavity 18 within which is housed the device of the present invention indicated generally at 20.
- the applicator 20 has an elongated tubular body 22 having a thin wall 24 of impermeable flexible sheet material such as a suitable plastic which may be easily bent inwardly by external digital force applied on opposite sides of the body.
- One end 26 is permanently closed, as by crimping and heat sealing, and the opposite end is initially closed but may be opened by the user when desired.
- the openable end includes a neck portion indicated generally at 30 having formed therein an outlet orifice 32 which is initially closed by a closure member indicated generally at 34 formed integrally with neck portion 30 of the body.
- Closure 34 is connected to neck 30 by a thin frangible annulus 36 surrounding the orifice 32.
- the closure is provided with a disk portion 38 to facilitate the grasping and twisting operation, and, opposite the frangible annulus 36, a sealing prong indicated generally at 40 projects from the disk and includes a shoulder 42 to assist in retaining the prong in rescaling position after initial use, as is shown in FIG. 3.
- a collar indicated generally at 46 Surrounding the neck 30 is a collar indicated generally at 46 made of absorbent spongy resilient material and impregnated with a suitable material such as silicone in ointment or gel form.
- Neck 30 is provided with an annular flange 48 adjacent to orifice 32, and collar 46 is retained on neck 30 by resilient abutting engagement against the flange.
- the outer surface of collar 46 may be slightly frusto-conical in contour as shown for reasons late? appearing.
- the auricle or pinna is effectively an outer continuation of the ear canal indicated generally at 60, merging with the canal at meatus 62.
- the user grasps the closed end 26 of the applicator 20 between thumb 54 and finger 56 and inserts the impregnated collar 46 into meatus 62 and partially into the adjacent portion of the ear canal. Desirably he then twists the applicator slightly, in order to make certain that a coating of ointment is deposited ringing the meatus, and then squeezes the applicator to force some of the liquid 28 outwardly of the applicator and into the ear canal proper.
- the coating thus shields the coated portion of the ear canal, and tends to retain the liquid in the ear, particularly when the liquid and the ointment are of similar materials such as the preferred silicone.
- the ointment-impregnated collar 46 contacts the meatus and adjacent portion of the ear canal before the liquid is squeezed out of the applicator. It has been found that, if the skin is first wetted by liquid silicone, the silicone ointment will not adhere well to the skin.
- the size of the spongy collar prevents its being inserted far enough into the canal to cause damage, and the resilience of the collar material similarly makes it safe to use without harm to the skin.
- An applicator for applying protective substance to the ear canal comprising:
- a container having therein a quantity of skin protective liquid and an outlet orifice for depositing said liquid in the ear canal;
- said collar being of a size as to prevent its total entry into the ear canal.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Acoustics & Sound (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Psychology (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
An applicator including a tubular collapsible body containing a liquid preparation, one end being permanently closed, the other end being initially closed and having means for opening it to provide an outlet orifice. Surrounding the orifice and attached to the applicator is a collar made of absorbent spongy material impregnated with a protective substance in ointment form. Desirably the liquid and ointment are silicone. The collar is somewhat larger in diameter than the ear canal and is desirably frusto-conical in outer contour so that it can be inserted into the meatus of the ear and partially into the adjacent portion of the ear canal. A slight twisting of applicator causes the collar to deposit a coating of ointment on the skin it contacts, and the user then squeezes the applicator body to force some of the liquid into the ear canal.
Description
llnited States Patent [191 Grossan 1 Aug. 26, 1975 l 5 EAR APPLICATOR [76] Inventor: Murray Grossan, 8930 Sepulveda [21] Appl. No.: 418,815
{52] US. Cl 128/261; 128/232 [51] Int. Cl A61m 35/00 [58] Field of Search 128/260, 261, 245, 248,
Primary ExaminerRichard A. Gaudet Assistant Examiner Henry S. Layton Attorney, Agent, or FirmMiketta, Glenny, Poms & Smith 5 7 ABSTRACT An applicator including a tubular collapsible body containing a liquid preparation, one end being permanently closed, the other end being initially closed and having means for opening it to provide an outlet orifice. Surrounding the orifice and attached to the applicator is a collar made of absorbent spongy material impregnated with a protective substance in ointment form. Desirably the liquid and ointment are silicone. The collar is somewhat larger in diameter than the ear canal and is desirably frusto-conical in outer contour so that it can be inserted into the meatus of the ear and partially into the adjacent portion of the ear canal. A slight twisting of applicator causes the collar to deposit a coating of ointment on the skin it contacts, and the user then squeezes the applicator body to force some of the liquid into the ear canal.
6 Claims, 4 Drawing Figures EAR APPLICATOR BACKGROUND AND FIELD OF THE INVENTION External otitis is frequently observed in swimmers,
divers and others whose ears are subjected to exposure to water. Even a humid climate is known to increase the incidence of external otitis, and swimmers ear is a well known form of the disease, typically characterized by maceration of the skin in the ear canal and resulting infection. Prolonged exposure to water, or even to humid atmosphere, tends to dissolve or otherwise remove cerumen, or ear wax, and the drying effect of such exposure on the skin gives rise to the maceration above mentioned. Furthermore, it is believed that cerumen may well have bactericidal or fungicidal properties which maintain the normal healthy state of the skin of the external ear canal, and loss of cerumen may accordingly increase the incidence of external otitis for this reason also.
Ear drops, particularly of silicone, have been used to provide a coating over the skin of the ear canal and thereby minimize removal of cerumen. However, such drops fall out of the ear fairly soon after application, especially if the user moves his head into a number of positions and orientations, as is typical in swimming.
The present invention provides means for application of a coating of a protective substance, preferably silicone, in the form of a gel or ointment to the meatus and adjacent portion of the ear canal and, substantially simultaneously, the application of liquid drops to the inner portion of the ear canal. Since cerumen is produced in the meatus and adjacent portions of the canal, the relatively stronger coating of silicone ointment on those surfaces minimizes loss of cerumen by the action of water, and also tends to inhibit the loss of the liquid ear drops from the inner portion of the ear canal. Moreover, clinical experience tends to indicate that the presence of any foreign substance, e.g. the ointment or gel above mentioned, on the cerumen producing area of the ear canal may actually stimulate the production of cerumen,
In accordance with the present invention, there is provided an applicator having a quantity of liquid preparation in a suitable container such as a collapsible tube having an outlet orifice, and a collar of absorbent spongy material surrounds the orifice and is impregnated with a suitable material in ointment or gel form. Thus, use of the device permits coating of the outer portion of the ear canal with the ointment and, immediately thereafter, application of liquid ear drops in the ear canal.
It is accordingly a principal object of the invention to provide a novel applicator for applying protective material to the meatus and the ear canal. Other objects are to provide such a device having a container from which liquid can be expelled from an orifice, and a collar of spongy material surrounding the orifice and impregnated with a protective material in ointment form; to provide such a device particularly effective in applying silicone to the ear canal to minimize loss of cerumen; and for other purposes as will be understood from the following description of a preferred embodiment of the invention, taken in conjunction with the appended drawing.
BRIEF DESCRIPTION OF THE DRAWING FIG. I is a side elevational view of an applicator of the present invention, in a package shown in section.
FIG. 2 is a partially sectional view of the applicator, taken on arrows Ill-11 of FIG. 1.
FIG. 3 is a fragmentary section view of the outlet end of the applicator with the closure member reinserted after initial use of the device.
FIG. 4 is a sectional view of the outer portion of the human ear, showing actual use of the applicator.
DETAILED DESCRIPTION In FIG. 1 there is shown an applicator in accordance with the present invention as it may be packaged for distribution in a conventional container which serves to prolong shelf life by minimizing drying out of the impregnated collar of the device. Such a container is indicated generally at 10 and includes a base sheet 12 of c ardboard or the like and a cover indicated generally at 14 desirably made of a preferably transparent plastic sheet material of the type used in the conventional blister pack and having a continuous marginal lip 16 attached to base sheet 12 by a suitable adhesive. Thus cover 14 and base 12 form a cavity 18 within which is housed the device of the present invention indicated generally at 20.
With reference to FIG. 2, the applicator 20 has an elongated tubular body 22 having a thin wall 24 of impermeable flexible sheet material such as a suitable plastic which may be easily bent inwardly by external digital force applied on opposite sides of the body. One end 26 is permanently closed, as by crimping and heat sealing, and the opposite end is initially closed but may be opened by the user when desired. More specifically, the openable end includes a neck portion indicated generally at 30 having formed therein an outlet orifice 32 which is initially closed by a closure member indicated generally at 34 formed integrally with neck portion 30 of the body. Closure 34 is connected to neck 30 by a thin frangible annulus 36 surrounding the orifice 32. Thus the user, just prior to first using the applicator, can twist the closure 34 relative to the applicator proper in order to break the attachment between the closure and the neck 30. The closure is provided with a disk portion 38 to facilitate the grasping and twisting operation, and, opposite the frangible annulus 36, a sealing prong indicated generally at 40 projects from the disk and includes a shoulder 42 to assist in retaining the prong in rescaling position after initial use, as is shown in FIG. 3.
Surrounding the neck 30 is a collar indicated generally at 46 made of absorbent spongy resilient material and impregnated with a suitable material such as silicone in ointment or gel form. Neck 30 is provided with an annular flange 48 adjacent to orifice 32, and collar 46 is retained on neck 30 by resilient abutting engagement against the flange. The outer surface of collar 46 may be slightly frusto-conical in contour as shown for reasons late? appearing.
Use of the applicator will be described with reference to FIG. 4. The auricle or pinna, indicated generally at 58, is effectively an outer continuation of the ear canal indicated generally at 60, merging with the canal at meatus 62.
The user grasps the closed end 26 of the applicator 20 between thumb 54 and finger 56 and inserts the impregnated collar 46 into meatus 62 and partially into the adjacent portion of the ear canal. Desirably he then twists the applicator slightly, in order to make certain that a coating of ointment is deposited ringing the meatus, and then squeezes the applicator to force some of the liquid 28 outwardly of the applicator and into the ear canal proper. The coating thus shields the coated portion of the ear canal, and tends to retain the liquid in the ear, particularly when the liquid and the ointment are of similar materials such as the preferred silicone.
It will thus be seen that the ointment-impregnated collar 46 contacts the meatus and adjacent portion of the ear canal before the liquid is squeezed out of the applicator. It has been found that, if the skin is first wetted by liquid silicone, the silicone ointment will not adhere well to the skin.
It is particularly to be noted that the size of the spongy collar prevents its being inserted far enough into the canal to cause damage, and the resilience of the collar material similarly makes it safe to use without harm to the skin.
I claim:
1. An applicator for applying protective substance to the ear canal comprising:
a container having therein a quantity of skin protective liquid and an outlet orifice for depositing said liquid in the ear canal;
and a collar of absorbent spongy material surrounding said orifice and impregnated with a skin protective substance in ointment form for depositing said ointment on the meatus of the ear,
said collar being of a size as to prevent its total entry into the ear canal.
2. The invention as defined in claim 1 including a removable closure means for said orifice.
3. The invention as defined in claim 1 wherein the skin protective liquid is silicone.
4. The invention as defined in claim 1 wherein said protective substance in ointment form is silicone.
5. The invention as defined in claim 1 wherein said collar is somewhat larger in diameter than the ear canal.
6. The invention as defined in claim 5 wherein the collar is frusto-conical in contour.
Claims (6)
1. An applicator for applying protective substance to the ear canal comprising: a container having therein a quantity of skin protective liquid and an outlet orifice for depositing said liquid in the ear canal; and a collar of absorbent spongy material surrounding said orifice and impregnated with a skin protective substance in ointment form for depositing said ointment on the meatus of the ear, said collar being of a size as to prevent its total entry into the ear canal.
2. The invention as defined in claim 1 including a removable closure means for said orifice.
3. The invention as defined in claim 1 wherein the skin protective liquid is silicone.
4. The invention as defined in claim 1 wherein said protective substance in ointment form is silicone.
5. The invention as defined in claim 1 wherein said collar is somewhat larger in diameter than the ear canal.
6. The invention as defined in claim 5 wherein the collar is frusto-conical in contour.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US418815A US3901233A (en) | 1973-11-26 | 1973-11-26 | Ear applicator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US418815A US3901233A (en) | 1973-11-26 | 1973-11-26 | Ear applicator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US3901233A true US3901233A (en) | 1975-08-26 |
Family
ID=23659677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US418815A Expired - Lifetime US3901233A (en) | 1973-11-26 | 1973-11-26 | Ear applicator |
Country Status (1)
| Country | Link |
|---|---|
| US (1) | US3901233A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4027670A (en) * | 1976-10-15 | 1977-06-07 | Bronner Emanuel H | Contraceptive device |
| US5300018A (en) * | 1990-08-24 | 1994-04-05 | Apdyne Medical Company | Applicator means for the application of anesthetizing fluids and the like to the tympanic membrane |
| US20060115520A1 (en) * | 2004-11-17 | 2006-06-01 | Vanek Patrick P | Fluid application device and method |
| US20100168638A1 (en) * | 2008-12-30 | 2010-07-01 | Otsuka America Pharmaceutical, Inc. | Fluid application device and method |
| US8858484B2 (en) | 2008-12-30 | 2014-10-14 | Otsuka America Pharmaceutical, Inc. | Fluid application device and method |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US770739A (en) * | 1904-03-17 | 1904-09-27 | Robert F Coleman | Syringe-nozzle. |
| US2185927A (en) * | 1937-02-16 | 1940-01-02 | Herman A Shelanski | Insufflator |
| US2629108A (en) * | 1950-10-25 | 1953-02-24 | Harold A Wickey | Invalid handling apparatus |
| US2837251A (en) * | 1954-11-15 | 1958-06-03 | Moir Douglas Ainslie | Dispensing device |
| US2863453A (en) * | 1956-12-04 | 1958-12-09 | Baxter Laboratories Inc | Syringe nozzle |
| US2879768A (en) * | 1956-03-13 | 1959-03-31 | Anderson Roy Algot | Two-way ear syringe |
-
1973
- 1973-11-26 US US418815A patent/US3901233A/en not_active Expired - Lifetime
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US770739A (en) * | 1904-03-17 | 1904-09-27 | Robert F Coleman | Syringe-nozzle. |
| US2185927A (en) * | 1937-02-16 | 1940-01-02 | Herman A Shelanski | Insufflator |
| US2629108A (en) * | 1950-10-25 | 1953-02-24 | Harold A Wickey | Invalid handling apparatus |
| US2837251A (en) * | 1954-11-15 | 1958-06-03 | Moir Douglas Ainslie | Dispensing device |
| US2879768A (en) * | 1956-03-13 | 1959-03-31 | Anderson Roy Algot | Two-way ear syringe |
| US2863453A (en) * | 1956-12-04 | 1958-12-09 | Baxter Laboratories Inc | Syringe nozzle |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4027670A (en) * | 1976-10-15 | 1977-06-07 | Bronner Emanuel H | Contraceptive device |
| US5300018A (en) * | 1990-08-24 | 1994-04-05 | Apdyne Medical Company | Applicator means for the application of anesthetizing fluids and the like to the tympanic membrane |
| US20060115520A1 (en) * | 2004-11-17 | 2006-06-01 | Vanek Patrick P | Fluid application device and method |
| US8911771B2 (en) | 2004-11-17 | 2014-12-16 | Otsuka America Pharmaceutical, Inc. | Fluid application device and method |
| US20100168638A1 (en) * | 2008-12-30 | 2010-07-01 | Otsuka America Pharmaceutical, Inc. | Fluid application device and method |
| US8858484B2 (en) | 2008-12-30 | 2014-10-14 | Otsuka America Pharmaceutical, Inc. | Fluid application device and method |
| US8979785B2 (en) | 2008-12-30 | 2015-03-17 | Otsuka Pharmaceutical Factory, Inc. | Fluid application device and method |
| US9566421B2 (en) | 2008-12-30 | 2017-02-14 | Otsuka America Pharmaceutical, Inc. | Fluid application device and method |
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