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US3680420B1 - - Google Patents

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Publication number
US3680420B1
US3680420B1 US3680420DA US3680420B1 US 3680420 B1 US3680420 B1 US 3680420B1 US 3680420D A US3680420D A US 3680420DA US 3680420 B1 US3680420 B1 US 3680420B1
Authority
US
United States
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RMC Inc
Original Assignee
RMC Inc 1802 WEST GRANT ROAD TUCSON ARIZONA 85745
RMC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22174759&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=US3680420(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by RMC Inc 1802 WEST GRANT ROAD TUCSON ARIZONA 85745, RMC Inc filed Critical RMC Inc 1802 WEST GRANT ROAD TUCSON ARIZONA 85745
Publication of US3680420A publication Critical patent/US3680420A/en
Assigned to RMC, INC. reassignment RMC, INC. ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: E. I. DJU PONT DE NEMOURS AND COMPANY
Application granted granted Critical
Publication of US3680420B1 publication Critical patent/US3680420B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42—Low-temperature sample treatment, e.g. cryofixation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T83/00—Cutting
    • Y10T83/222—With receptacle or support for cut product
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T83/00—Cutting
    • Y10T83/283—With means to control or modify temperature of apparatus or work
    • Y10T83/293—Of tool

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
US82994A 1970-10-22 1970-10-22 Cryogenic microtome apparatus Expired - Lifetime US3680420A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8299470A 1970-10-22 1970-10-22

Publications (2)

Publication Number Publication Date
US3680420A US3680420A (en) 1972-08-01
US3680420B1 true US3680420B1 (en) 1989-07-11

Family

ID=22174759

Family Applications (1)

Application Number Title Priority Date Filing Date
US82994A Expired - Lifetime US3680420A (en) 1970-10-22 1970-10-22 Cryogenic microtome apparatus

Country Status (1)

Country Link
US (1) US3680420A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987002130A1 (en) * 1985-10-04 1987-04-09 Brian Laurence Jackson Improvements in cryostatic microtomes
US5050470A (en) * 1989-05-15 1991-09-24 Ward John L Receiver for specimens from cryogenic microtome
DE4028806A1 (en) * 1990-09-11 1992-03-12 Leica Ag Cryogenic microtome with reciprocating specimen carrier arm - sealed against cryogen leakage by fine air gap
US5533342A (en) * 1995-02-08 1996-07-09 Gordon; Abe Semi-automated cryostat
US5713255A (en) * 1992-07-10 1998-02-03 Microm Laborgerate Gmbh Process and apparatus for the production of thin sections by means of a microtome
US20050220674A1 (en) * 2004-04-01 2005-10-06 Gal Shafirstein Tissue electro-sectioning apparatus
US20130019725A1 (en) * 2011-07-20 2013-01-24 Vertex Pharmaceuticals, Inc. Device to collect and segregate tissue samples sectioned on a microtome
US10422724B2 (en) * 2016-11-14 2019-09-24 Sakura Finetek U.S.A., Inc. Microtome waste removal assembly
CN115042250A (en) * 2022-06-06 2022-09-13 广州维格斯生物科技有限公司 Metal slicing mechanism working at normal temperature
US11808679B2 (en) 2022-01-27 2023-11-07 Expresslo Llc Method and apparatus for cryogenic and environmental controlled specimen handling

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3218896A (en) * 1963-04-08 1965-11-23 Ames Lab Tek Inc Specimen freezing device for use with a microtome
AT260573B (en) * 1966-09-08 1968-03-11 Zentrum Fuer Elektronenmikrosk Equipment for the production of cooling cuts for microscopy

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987002130A1 (en) * 1985-10-04 1987-04-09 Brian Laurence Jackson Improvements in cryostatic microtomes
US5050470A (en) * 1989-05-15 1991-09-24 Ward John L Receiver for specimens from cryogenic microtome
DE4028806A1 (en) * 1990-09-11 1992-03-12 Leica Ag Cryogenic microtome with reciprocating specimen carrier arm - sealed against cryogen leakage by fine air gap
US5299481A (en) * 1990-09-11 1994-04-05 Leica Aktiengesellschaft Carrier arm seal for a microtome of ultramicrotome
DE4028806C2 (en) * 1990-09-11 1998-08-27 Leica Ag Microtome, especially ultramicrotome with a cooling chamber
US5713255A (en) * 1992-07-10 1998-02-03 Microm Laborgerate Gmbh Process and apparatus for the production of thin sections by means of a microtome
US5533342A (en) * 1995-02-08 1996-07-09 Gordon; Abe Semi-automated cryostat
US20050238539A1 (en) * 2004-04-01 2005-10-27 Gal Shafirstein Apparatus for automated fresh tissue sectioning
US20050220674A1 (en) * 2004-04-01 2005-10-06 Gal Shafirstein Tissue electro-sectioning apparatus
US20130019725A1 (en) * 2011-07-20 2013-01-24 Vertex Pharmaceuticals, Inc. Device to collect and segregate tissue samples sectioned on a microtome
US8967024B2 (en) * 2011-07-20 2015-03-03 Vertex Pharmaceuticals, Inc. Device to collect and segregate tissue samples sectioned on a microtome
US10422724B2 (en) * 2016-11-14 2019-09-24 Sakura Finetek U.S.A., Inc. Microtome waste removal assembly
US10466143B2 (en) * 2016-11-14 2019-11-05 Sakura Finetek U.S.A., Inc. Microtome storage assembly
US11808679B2 (en) 2022-01-27 2023-11-07 Expresslo Llc Method and apparatus for cryogenic and environmental controlled specimen handling
CN115042250A (en) * 2022-06-06 2022-09-13 广州维格斯生物科技有限公司 Metal slicing mechanism working at normal temperature
CN115042250B (en) * 2022-06-06 2024-04-09 广州维格斯生物科技有限公司 Metal slicing mechanism working at normal temperature

Also Published As

Publication number Publication date
US3680420A (en) 1972-08-01

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Legal Events

Date Code Title Description
STCF Information on status: patent grant

Free format text: PATENTED FILE - (OLD CASE ADDED FOR FILE TRACKING PURPOSES)

AS Assignment

Owner name: RMC, INC. 1802 WEST GRANT ROAD TUCSON, ARIZONA 857

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:E. I. DJU PONT DE NEMOURS AND COMPANY;REEL/FRAME:004568/0602

Effective date: 19860429

RR Request for reexamination filed

Effective date: 19870128

B1 Reexamination certificate first reexamination
DC Disclaimer filed

Effective date: 19890403