UA89216C2 - Таблетка леветирацетама продолжительного высвобождения - Google Patents
Таблетка леветирацетама продолжительного высвобожденияInfo
- Publication number
- UA89216C2 UA89216C2 UAA200709290A UAA200709290A UA89216C2 UA 89216 C2 UA89216 C2 UA 89216C2 UA A200709290 A UAA200709290 A UA A200709290A UA A200709290 A UAA200709290 A UA A200709290A UA 89216 C2 UA89216 C2 UA 89216C2
- Authority
- UA
- Ukraine
- Prior art keywords
- levetiracetam
- extended release
- core
- tablet
- blood plasma
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN81MU2005 | 2005-01-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
UA89216C2 true UA89216C2 (ru) | 2010-01-11 |
Family
ID=35788072
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200709290A UA89216C2 (ru) | 2005-01-27 | 2005-12-08 | Таблетка леветирацетама продолжительного высвобождения |
Country Status (18)
Country | Link |
---|---|
US (4) | US7858122B2 (ru) |
EP (1) | EP1843761B1 (ru) |
JP (1) | JP5739080B2 (ru) |
KR (1) | KR20070095456A (ru) |
CN (1) | CN101111245A (ru) |
AU (1) | AU2005325930B2 (ru) |
BR (1) | BRPI0518506A2 (ru) |
CA (1) | CA2595988A1 (ru) |
DE (1) | DE05815688T1 (ru) |
EA (1) | EA014249B1 (ru) |
ES (1) | ES2294979T1 (ru) |
IL (1) | IL184822A0 (ru) |
MX (1) | MX2007009088A (ru) |
NO (1) | NO20074316L (ru) |
NZ (1) | NZ556630A (ru) |
UA (1) | UA89216C2 (ru) |
WO (1) | WO2006080029A1 (ru) |
ZA (1) | ZA200707250B (ru) |
Families Citing this family (69)
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ES2403069T3 (es) | 2005-02-22 | 2013-05-13 | Sun Pharma Advanced Research Company Ltd | Composición oral de liberación controlada que contiene levetiracetam |
AU2006228947A1 (en) | 2005-03-30 | 2006-10-05 | Mylan Pharmaceuticals Ulc | Combined-step process for pharmaceutical compositions |
PE20070216A1 (es) * | 2005-07-26 | 2007-03-27 | Ucb Sa | Nuevas composiciones farmaceuticas que comprenden levetiracetam y proceso para su preparacion |
ATE496623T1 (de) | 2006-04-26 | 2011-02-15 | Supernus Pharmaceuticals Inc | Oxcarbazepin-zubereitungen für kontrollierte freisetzung mit sigmoidalem freisetzungsprofil |
US20080014264A1 (en) * | 2006-07-13 | 2008-01-17 | Ucb, S.A. | Novel pharmaceutical compositions comprising levetiracetam |
WO2008062446A2 (en) * | 2006-09-14 | 2008-05-29 | Alembic Limited | An extended release composition of levetiracetam, which exhibits no adverse food effect |
US8444758B2 (en) * | 2006-10-19 | 2013-05-21 | Eastman Chemical Company | Low voc additives for extending the wet edge and open time of aqueous coatings |
US20080092776A1 (en) * | 2006-10-19 | 2008-04-24 | Rebecca Reid Stockl | Low-VOC additives for extending wet edge and open times of coatings |
FR2912056B1 (fr) * | 2007-02-05 | 2009-12-18 | Rd Pharmagal | Composition a liberation prolongee de levetiracetam et procede de preparation |
US20120003307A1 (en) * | 2007-11-29 | 2012-01-05 | Ranbaxy Laboratories Limited | Levetiracetam controlled release composition |
AU2008346118A1 (en) * | 2007-12-21 | 2009-07-16 | Alembic Limited | Coated extended release pharmaceutical compositions of levetiracetam |
US20090263481A1 (en) * | 2008-04-17 | 2009-10-22 | Atul Vishvanath Patil | Levetiracetam formulations |
WO2009144286A1 (en) * | 2008-05-30 | 2009-12-03 | Ucb Pharma, S.A. | Pharmaceutical compositions comprising brivaracetam |
CN101623250B (zh) * | 2008-07-09 | 2013-02-27 | 北京德众万全药物技术开发有限公司 | 一种左乙拉西坦药物组合物及其制备方法 |
US20100055177A1 (en) * | 2008-08-29 | 2010-03-04 | Dafna Arieli | Modified release composition of levetiracetam and process for the preparation thereof |
WO2010026467A2 (en) | 2008-09-04 | 2010-03-11 | Torrent Pharmaceuticals Ltd. | Controlled release dosage form of high solubility active ingredient |
JP5917148B2 (ja) * | 2008-10-16 | 2016-05-11 | ザ ジョーンズ ホプキンズ ユニバーシティThe Johns Hopkins University | 認知機能を改善するための方法および組成物 |
US8778398B2 (en) | 2008-11-04 | 2014-07-15 | Jazz Pharmaceuticals, Inc. | Immediate release formulations and dosage forms of gamma-hydroxybutyrate |
ES2602606T3 (es) * | 2008-11-18 | 2017-02-21 | Ucb Biopharma Sprl | Formulaciones de liberación prolongada que comprenden un derivado de 2-oxo-1-pirrolidina |
CN101422442A (zh) * | 2008-12-09 | 2009-05-06 | 沈阳药科大学 | 左乙拉西坦渗透泵控释片及其制备方法 |
US20100159009A1 (en) * | 2008-12-24 | 2010-06-24 | Zhongshui Yu | Controlled-release formulations |
US20100172979A1 (en) * | 2008-12-24 | 2010-07-08 | Zhongshui Yu | Controlled-release formulations |
CN101919811A (zh) * | 2009-06-09 | 2010-12-22 | 北京博时安泰液体制剂科技有限公司 | 一种左乙拉西坦注射液及其制备方法 |
TR200905670A1 (tr) | 2009-07-22 | 2011-02-21 | Sanovel �La� San.Ve T�C.A.�. | Uzatılmış salım sağlayan levetirasetam farmasötik bileşimleri |
CN101647789B (zh) * | 2009-09-01 | 2011-08-17 | 天津药物研究院药业有限责任公司 | 左乙拉西坦缓释微丸胶囊制剂 |
EP2298290A1 (en) | 2009-09-16 | 2011-03-23 | LEK Pharmaceuticals d.d. | Controlled release composition comprising levetiracetam |
JP5968300B2 (ja) | 2010-03-24 | 2016-08-10 | ジャズ、ファーマシューティカルズ、インコーポレイテッドJazz Pharmaceuticals Inc. | 高用量、水溶性及び吸湿性薬剤基質用の制御放出性剤形 |
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US9333175B2 (en) | 2010-06-16 | 2016-05-10 | Mylan Inc. | Controlled release levetiracetam formulations and methods for producing the same |
KR20120055313A (ko) * | 2010-11-23 | 2012-05-31 | 주식회사 바이오파마티스 | 레베티라세탐 또는 이의 약학적으로 허용되는 염을 포함하는 용출 안정성이 개선된 서방형 약학 조성물 및 이의 제조방법 |
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EA034167B8 (ru) * | 2015-05-22 | 2021-04-27 | Эйджинбайо, Инк. | Фармацевтические композиции леветирацетама пролонгированного высвобождения |
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CA2937365C (en) | 2016-03-29 | 2018-09-18 | F. Hoffmann-La Roche Ag | Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same |
JP6422464B2 (ja) * | 2016-05-19 | 2018-11-14 | エルメッド エーザイ株式会社 | レベチラセタム含有医薬組成物及びその製造方法、並びにレベチラセタム含有医薬組成物の崩壊及び溶出の少なくともいずれかの遅延防止方法、及びレベチラセタム含有医薬組成物の崩壊及び溶出の少なくともいずれかの遅延防止剤 |
CN105997914A (zh) * | 2016-07-20 | 2016-10-12 | 南通雅本化学有限公司 | 一种左乙拉西坦组合药物及其制备方法 |
US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US12186296B1 (en) | 2016-07-22 | 2025-01-07 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
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JP2020094024A (ja) * | 2018-12-14 | 2020-06-18 | エルメッド株式会社 | レベチラセタム含有フィルムコート錠及びその製造方法、並びにレベチラセタム含有フィルムコート錠の変色抑制方法 |
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BRPI0417043A (pt) * | 2003-12-01 | 2007-02-06 | Lifecycle Pharma As | composição farmacêutica, forma de dosagem sólida, método de manufatura de forma de dosagem sólida, e, uso da composição |
US20050250838A1 (en) * | 2004-05-04 | 2005-11-10 | Challapalli Prasad V | Formulation for sustained delivery |
EP1765305A4 (en) * | 2004-07-09 | 2008-06-04 | Drugtech Corp | REGULATED PHASE COMPOSITION TECHNOLOGY USED AS ENHANCED MEDICATION PROTECTION METHOD |
ES2403069T3 (es) | 2005-02-22 | 2013-05-13 | Sun Pharma Advanced Research Company Ltd | Composición oral de liberación controlada que contiene levetiracetam |
PE20070216A1 (es) | 2005-07-26 | 2007-03-27 | Ucb Sa | Nuevas composiciones farmaceuticas que comprenden levetiracetam y proceso para su preparacion |
DK1912626T3 (en) | 2005-08-08 | 2016-08-01 | Abbvie Deutschland | Dosage forms with improved bioavailability |
US20080014264A1 (en) * | 2006-07-13 | 2008-01-17 | Ucb, S.A. | Novel pharmaceutical compositions comprising levetiracetam |
WO2008062446A2 (en) | 2006-09-14 | 2008-05-29 | Alembic Limited | An extended release composition of levetiracetam, which exhibits no adverse food effect |
-
2005
- 2005-08-12 NZ NZ556630A patent/NZ556630A/en not_active IP Right Cessation
- 2005-08-12 ES ES05815688T patent/ES2294979T1/es active Pending
- 2005-08-12 MX MX2007009088A patent/MX2007009088A/es active IP Right Grant
- 2005-08-12 BR BRPI0518506-8A patent/BRPI0518506A2/pt not_active IP Right Cessation
- 2005-08-12 DE DE05815688T patent/DE05815688T1/de active Pending
- 2005-08-12 EP EP05815688.6A patent/EP1843761B1/en active Active
- 2005-08-12 KR KR1020077019524A patent/KR20070095456A/ko not_active Application Discontinuation
- 2005-08-12 AU AU2005325930A patent/AU2005325930B2/en not_active Ceased
- 2005-08-12 CA CA002595988A patent/CA2595988A1/en not_active Abandoned
- 2005-08-12 CN CNA2005800473165A patent/CN101111245A/zh active Pending
- 2005-08-12 ZA ZA200707250A patent/ZA200707250B/xx unknown
- 2005-08-12 JP JP2007552811A patent/JP5739080B2/ja not_active Expired - Fee Related
- 2005-08-12 EA EA200701575A patent/EA014249B1/ru not_active IP Right Cessation
- 2005-08-12 WO PCT/IN2005/000275 patent/WO2006080029A1/en active Search and Examination
- 2005-08-31 US US11/215,947 patent/US7858122B2/en active Active
- 2005-12-08 UA UAA200709290A patent/UA89216C2/ru unknown
-
2006
- 2006-10-20 US US11/583,888 patent/US7863316B2/en active Active
-
2007
- 2007-07-24 IL IL184822A patent/IL184822A0/en unknown
- 2007-08-23 NO NO20074316A patent/NO20074316L/no not_active Application Discontinuation
-
2010
- 2010-11-09 US US12/942,585 patent/US20110064807A1/en not_active Abandoned
- 2010-11-12 US US12/944,936 patent/US20110064808A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
IL184822A0 (en) | 2007-12-03 |
ES2294979T1 (es) | 2008-04-16 |
WO2006080029A1 (en) | 2006-08-03 |
US20060165796A1 (en) | 2006-07-27 |
KR20070095456A (ko) | 2007-09-28 |
MX2007009088A (es) | 2007-09-13 |
US20070092569A1 (en) | 2007-04-26 |
EA014249B1 (ru) | 2010-10-29 |
AU2005325930A1 (en) | 2006-08-03 |
DE05815688T1 (de) | 2008-06-26 |
US7858122B2 (en) | 2010-12-28 |
EP1843761B1 (en) | 2018-01-31 |
US7863316B2 (en) | 2011-01-04 |
JP2008528571A (ja) | 2008-07-31 |
ZA200707250B (en) | 2009-06-24 |
US20110064808A1 (en) | 2011-03-17 |
CA2595988A1 (en) | 2006-08-03 |
US20110064807A1 (en) | 2011-03-17 |
NZ556630A (en) | 2010-12-24 |
CN101111245A (zh) | 2008-01-23 |
EP1843761A1 (en) | 2007-10-17 |
BRPI0518506A2 (pt) | 2008-12-02 |
AU2005325930B2 (en) | 2012-01-19 |
EA200701575A1 (ru) | 2008-02-28 |
NO20074316L (no) | 2007-08-23 |
JP5739080B2 (ja) | 2015-06-24 |
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