UA75727C2 - Oral pharmaceutical compositions for controlled release of propiverine - Google Patents
Oral pharmaceutical compositions for controlled release of propiverine Download PDFInfo
- Publication number
- UA75727C2 UA75727C2 UA2004042681A UA2004042681A UA75727C2 UA 75727 C2 UA75727 C2 UA 75727C2 UA 2004042681 A UA2004042681 A UA 2004042681A UA 2004042681 A UA2004042681 A UA 2004042681A UA 75727 C2 UA75727 C2 UA 75727C2
- Authority
- UA
- Ukraine
- Prior art keywords
- propiverine
- release
- granules
- active substance
- hydrochloride
- Prior art date
Links
- 229960003510 propiverine Drugs 0.000 title abstract description 122
- QPCVHQBVMYCJOM-UHFFFAOYSA-N Propiverine Chemical compound C=1C=CC=CC=1C(C=1C=CC=CC=1)(OCCC)C(=O)OC1CCN(C)CC1 QPCVHQBVMYCJOM-UHFFFAOYSA-N 0.000 title abstract description 120
- 238000013270 controlled release Methods 0.000 title abstract description 6
- 239000008203 oral pharmaceutical composition Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract description 83
- 239000000126 substance Substances 0.000 abstract description 65
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- 150000003839 salts Chemical class 0.000 abstract description 20
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- 239000004480 active ingredient Substances 0.000 abstract description 4
- 238000013265 extended release Methods 0.000 abstract 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 172
- 239000008187 granular material Substances 0.000 description 139
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 92
- 239000013543 active substance Substances 0.000 description 88
- 238000000034 method Methods 0.000 description 45
- HWMFFWCDLWDYGX-UHFFFAOYSA-N n-(4-aminophenyl)furan-2-carboxamide Chemical compound C1=CC(N)=CC=C1NC(=O)C1=CC=CO1 HWMFFWCDLWDYGX-UHFFFAOYSA-N 0.000 description 45
- 229960001187 propiverine hydrochloride Drugs 0.000 description 45
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- 239000000463 material Substances 0.000 description 30
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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Landscapes
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- Neurology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10149674A DE10149674A1 (de) | 2001-10-09 | 2001-10-09 | Orale Darreichungsformen für Propiverin oder seinen pharmazeutisch annehmbaren Salzen mit verlängerter Wirkstoffreisetzung |
| PCT/EP2002/011253 WO2003030869A1 (de) | 2001-10-09 | 2002-10-08 | Orale darreichungsformen für propiverin oder seinen pharmazeutisch annehmbaren salzen mit verlängerter wirkstofffreisetzung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA75727C2 true UA75727C2 (en) | 2006-05-15 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| UA2004042681A UA75727C2 (en) | 2001-10-09 | 2002-08-10 | Oral pharmaceutical compositions for controlled release of propiverine |
Country Status (33)
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| US (1) | US7943176B2 (pl) |
| EP (1) | EP1435915B1 (pl) |
| JP (1) | JP4192096B2 (pl) |
| KR (1) | KR100723964B1 (pl) |
| CN (1) | CN100473382C (pl) |
| AR (1) | AR036768A1 (pl) |
| AT (1) | ATE401865T1 (pl) |
| AU (1) | AU2002346973B8 (pl) |
| CA (1) | CA2462482C (pl) |
| CY (1) | CY1108426T1 (pl) |
| DE (2) | DE10149674A1 (pl) |
| DK (1) | DK1435915T3 (pl) |
| EA (1) | EA008862B1 (pl) |
| EG (1) | EG25542A (pl) |
| ES (2) | ES2299287B1 (pl) |
| HK (1) | HK1067310A1 (pl) |
| HR (1) | HRP20040323C1 (pl) |
| HU (1) | HU227878B1 (pl) |
| IL (2) | IL160977A0 (pl) |
| IS (1) | IS2571B (pl) |
| JO (1) | JO2555B1 (pl) |
| ME (2) | ME00327B (pl) |
| MX (1) | MXPA04003132A (pl) |
| MY (1) | MY142403A (pl) |
| PE (1) | PE20030399A1 (pl) |
| PL (1) | PL208229B1 (pl) |
| PT (1) | PT1435915E (pl) |
| RS (1) | RS50924B (pl) |
| SI (1) | SI1435915T1 (pl) |
| TW (1) | TWI315204B (pl) |
| UA (1) | UA75727C2 (pl) |
| WO (1) | WO2003030869A1 (pl) |
| ZA (1) | ZA200402437B (pl) |
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| US7183410B2 (en) * | 2001-08-02 | 2007-02-27 | Bidachem S.P.A. | Stable polymorph of flibanserin |
| US20030060475A1 (en) * | 2001-08-10 | 2003-03-27 | Boehringer Ingelheim Pharma Kg | Method of using flibanserin for neuroprotection |
| DE10149674A1 (de) | 2001-10-09 | 2003-04-24 | Apogepha Arzneimittel Gmbh | Orale Darreichungsformen für Propiverin oder seinen pharmazeutisch annehmbaren Salzen mit verlängerter Wirkstoffreisetzung |
| UA78974C2 (en) * | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| DE10209982A1 (de) * | 2002-03-07 | 2003-09-25 | Boehringer Ingelheim Pharma | Oral zu applizierende Darreichungsform für schwerlösliche basische Wirkstoffe |
| US20030181488A1 (en) | 2002-03-07 | 2003-09-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof |
| US20040048877A1 (en) * | 2002-05-22 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions containing flibanserin |
| CA2543689A1 (en) * | 2003-10-31 | 2005-05-12 | Hexal Ag | Pharmaceutical actve-ingredient-containing formulation with coating |
| DE10353186A1 (de) * | 2003-11-13 | 2005-06-16 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform, enthaltend eine in Bezug auf die Wirkstoffabgabe modulatorisch wirkende Substanz |
| DE10353196A1 (de) * | 2003-11-13 | 2005-06-16 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform mit einer die Abgabe einer modulatorischen Substanz beeinflussenden Matrix |
| EP3216449A1 (en) * | 2003-11-14 | 2017-09-13 | EA Pharma Co., Ltd. | Oral administration preparation of phenylalanine derivatives |
| US8007827B2 (en) * | 2004-04-02 | 2011-08-30 | Impax Laboratories, Inc. | Pharmaceutical dosage forms having immediate release and/or controlled release properties |
| US20060025420A1 (en) * | 2004-07-30 | 2006-02-02 | Boehringer Ingelheimn International GmbH | Pharmaceutical compositions for the treatment of female sexual disorders |
| JP4895819B2 (ja) * | 2004-10-29 | 2012-03-14 | 大鵬薬品工業株式会社 | プロピベリン含有経口粉粒状製剤及びその製造法 |
| WO2006096434A2 (en) * | 2005-03-04 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of anxiety disorders |
| WO2006096439A2 (en) * | 2005-03-04 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of schizophrenia and related diseases |
| WO2006100281A2 (en) | 2005-03-22 | 2006-09-28 | Losan Pharma Gmbh | Solubilized ibuprofen |
| JP2008534530A (ja) * | 2005-03-29 | 2008-08-28 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | 活性成分放出に関して調節作用を有する物質を有するペレットを含有している多粒子薬剤形 |
| EP1868580A1 (en) * | 2005-03-29 | 2007-12-26 | Evonik Röhm GmbH | Multiparticulate pharmaceutical form comprising pellets with a matrix which influences the delivery of a modulatory substance |
| CA2608363A1 (en) * | 2005-05-19 | 2006-11-23 | Boehringer Ingelheim International Gmbh | Method for the treatment of drug-induced sexual dysfunction |
| PL1912650T3 (pl) * | 2005-08-03 | 2018-01-31 | Sprout Pharmaceuticals Inc | Zastosowanie flibanseryny w leczeniu otyłości |
| CA2626134C (en) * | 2005-10-29 | 2013-12-24 | Boehringer Ingelheim International Gmbh | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
| US20070105869A1 (en) * | 2005-11-08 | 2007-05-10 | Stephane Pollentier | Use of flibanserin for the treatment of pre-menopausal sexual desire disorders |
| AU2007211091B8 (en) * | 2006-01-27 | 2013-08-29 | Adare Pharmaceuticals, Inc. | Drug delivery systems comprising weakly basic selective serotonin 5-HT3 blocking agent and organic acids |
| RU2428176C2 (ru) * | 2006-01-27 | 2011-09-10 | Юранд, Инк. | Системы доставки лекарственного средства, содержащие слабоосновные лекарственные средства и органические кислоты |
| LT1993559T (lt) | 2006-02-03 | 2016-11-10 | Opko Renal, Llc | Vitamino d nepakankamumo ir deficito gydymas su 25-hidroksivitaminu d2 ir 25-hidroksivitaminu d3 |
| EP2021006B1 (en) * | 2006-05-09 | 2015-08-12 | Sprout Pharmaceuticals, Inc. | Use of flibanserin for the treatment of post-menopausal sexual desire disorders |
| PT3357496T (pt) | 2006-06-21 | 2020-05-12 | Opko Ireland Global Holdings Ltd | Terapia utilizando um agente de repleção de vitamina d e um agente de substituição hormonal de vitamina d |
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| EA200900264A1 (ru) | 2006-08-14 | 2009-08-28 | Бёрингер Ингельхайм Интернациональ Гмбх | Композиции флибансерина и способ их приготовления |
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| US8361488B2 (en) | 2007-04-25 | 2013-01-29 | Cytochroma Inc. | Methods and compositions for controlled release oral dosage of a vitamin D compound |
| EP2148684B1 (en) | 2007-04-25 | 2013-01-16 | Cytochroma Inc. | Method of treating vitamin d insufficiency and deficiency |
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| WO2010062308A1 (en) | 2008-10-28 | 2010-06-03 | The Board Of Trustees Of The Leland Stanford Junior University | Modulators of aldehyde dehydrogenase and methods of use thereof |
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- 2002-10-08 DE DE50212546T patent/DE50212546D1/de not_active Expired - Lifetime
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