UA70974C2 - Ванкорезміцин (варіанти), штам amycolatopsis виду hil-006734, dsm 12216, що його продукує, та фармацевтична композиція, яка має антибіотичну активність - Google Patents
Ванкорезміцин (варіанти), штам amycolatopsis виду hil-006734, dsm 12216, що його продукує, та фармацевтична композиція, яка має антибіотичну активністьInfo
- Publication number
- UA70974C2 UA70974C2 UA2001063871A UA01063871A UA70974C2 UA 70974 C2 UA70974 C2 UA 70974C2 UA 2001063871 A UA2001063871 A UA 2001063871A UA 01063871 A UA01063871 A UA 01063871A UA 70974 C2 UA70974 C2 UA 70974C2
- Authority
- UA
- Ukraine
- Prior art keywords
- vancoresmycin
- dsm
- variants
- producing
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Нова сполука, що названа ванкорезміцин, яку одержують культивуванням мікроорганізму Amycolatopsis виду HIL-006734, DSM12216 та її фармацевтично прийнятні солі і похідні у всіх стереоізомерних і таутомерних формах. Даний винахід також стосується штаму Amycolatopsis виду HIL-006734, DSM12216 та фармацевтичної композиції, що має антибіотичну активність, яка містить ефективну кількість ванкорезміцину або його фармацевтично прийнятної солі чи похідного та фармацевтично прийнятний носій. Ванкорезміцин діє проти резистентних до ванкоміцину та тейкопланіну штамів Staphylococcus aureus, що збільшує ефективність лікування інфекцій, які викликані MRSA (метицилінрезистентними стафілококами).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98121299 | 1998-11-09 | ||
| PCT/EP1999/008415 WO2000028064A1 (en) | 1998-11-09 | 1999-11-04 | Vancoresmycin, a process for its production and its use as a pharmaceutical |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA70974C2 true UA70974C2 (uk) | 2004-11-15 |
Family
ID=8232941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2001063871A UA70974C2 (uk) | 1998-11-09 | 1999-11-04 | Ванкорезміцин (варіанти), штам amycolatopsis виду hil-006734, dsm 12216, що його продукує, та фармацевтична композиція, яка має антибіотичну активність |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US6387943B1 (uk) |
| EP (1) | EP1129208B1 (uk) |
| JP (1) | JP2002529477A (uk) |
| KR (1) | KR100623405B1 (uk) |
| CN (1) | CN1325656C (uk) |
| AR (1) | AR024226A1 (uk) |
| AT (1) | ATE225854T1 (uk) |
| AU (1) | AU761782B2 (uk) |
| BR (1) | BR9915161A (uk) |
| CA (1) | CA2351222A1 (uk) |
| CZ (1) | CZ20011593A3 (uk) |
| DE (1) | DE69903465T2 (uk) |
| DK (1) | DK1129208T3 (uk) |
| ES (1) | ES2181506T3 (uk) |
| HK (1) | HK1041026B (uk) |
| HU (1) | HU224610B1 (uk) |
| ID (1) | ID28381A (uk) |
| IL (1) | IL142848A0 (uk) |
| PL (1) | PL195995B1 (uk) |
| PT (1) | PT1129208E (uk) |
| RU (1) | RU2228337C2 (uk) |
| SI (1) | SI1129208T1 (uk) |
| TR (1) | TR200101279T2 (uk) |
| UA (1) | UA70974C2 (uk) |
| WO (1) | WO2000028064A1 (uk) |
| ZA (1) | ZA200103191B (uk) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10060810A1 (de) | 2000-12-07 | 2002-06-20 | Aventis Pharma Gmbh | Coniosetin und Derivate davon, Verfahren zur Herstellung und Verwendung derselben |
| WO2006069386A1 (en) * | 2004-12-22 | 2006-06-29 | Teva Gyógyszergyár Zártköruen Muködo Részvénytársaság | Method of purifying tacrolimus |
| US8552208B2 (en) * | 2007-09-11 | 2013-10-08 | University of Tennesseee Research Foundation | Analogs of tetramic acid |
| JP6465299B2 (ja) * | 2015-05-29 | 2019-02-06 | 株式会社山田養蜂場本社 | 蜂蜜画分 |
| CN109608523B (zh) * | 2018-11-23 | 2023-01-10 | 江苏九阳生物制药有限公司 | 一种高纯度替考拉宁的生产工艺 |
| US20230106760A1 (en) * | 2020-03-17 | 2023-04-06 | The United States Of America,As Represented By The Secretary,Department Of Health And Human Services | Antibacterial and antifungal polyketides from environmental amycolatopsis spp |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05163289A (ja) * | 1991-08-27 | 1993-06-29 | Microbial Chem Res Found | 新規な免疫抑制物質、ｍｉ７１０−５１ｆ６物質およびその製造法 |
| JP3192723B2 (ja) * | 1992-01-29 | 2001-07-30 | 明治製菓株式会社 | 新規マクロライド抗生物質ｓｆ２７４８ｂ物質、ｓｆ２７４８ｃ１物質、ｓｆ２７４８ｄ物質およびｓｆ２７４８ｅ物質ならびにその製造法 |
| JP3107455B2 (ja) * | 1992-05-08 | 2000-11-06 | 財団法人微生物化学研究会 | 新規抗生物質ｍｉ４８１−４２ｆ４−ａ及びその製造方法 |
| JPH09157266A (ja) * | 1995-12-04 | 1997-06-17 | Microbial Chem Res Found | 新規抗生物質エポキシキノマイシンａおよびｂとその製造法 |
| JPH1011477A (ja) * | 1996-06-26 | 1998-01-16 | Dainippon Printing Co Ltd | 集積回路のシミュレーション用入力ファイルの作成装置 |
| EP0818539A1 (en) * | 1996-07-11 | 1998-01-14 | Hoechst Aktiengesellschaft | Methylsulfomycin I, a process for its production and its use |
-
1999
- 1999-11-04 ES ES99971862T patent/ES2181506T3/es not_active Expired - Lifetime
- 1999-11-04 RU RU2001116104/13A patent/RU2228337C2/ru not_active IP Right Cessation
- 1999-11-04 CN CNB998131121A patent/CN1325656C/zh not_active Expired - Fee Related
- 1999-11-04 DK DK99971862T patent/DK1129208T3/da active
- 1999-11-04 AT AT99971862T patent/ATE225854T1/de not_active IP Right Cessation
- 1999-11-04 BR BR9915161-8A patent/BR9915161A/pt not_active Application Discontinuation
- 1999-11-04 PL PL99347658A patent/PL195995B1/pl not_active IP Right Cessation
- 1999-11-04 CZ CZ20011593A patent/CZ20011593A3/cs unknown
- 1999-11-04 KR KR1020017005727A patent/KR100623405B1/ko not_active IP Right Cessation
- 1999-11-04 IL IL14284899A patent/IL142848A0/xx not_active IP Right Cessation
- 1999-11-04 HU HU0104213A patent/HU224610B1/hu not_active IP Right Cessation
- 1999-11-04 EP EP99971862A patent/EP1129208B1/en not_active Expired - Lifetime
- 1999-11-04 CA CA002351222A patent/CA2351222A1/en not_active Abandoned
- 1999-11-04 UA UA2001063871A patent/UA70974C2/uk unknown
- 1999-11-04 PT PT99971862T patent/PT1129208E/pt unknown
- 1999-11-04 DE DE69903465T patent/DE69903465T2/de not_active Expired - Fee Related
- 1999-11-04 AU AU13787/00A patent/AU761782B2/en not_active Ceased
- 1999-11-04 WO PCT/EP1999/008415 patent/WO2000028064A1/en active IP Right Grant
- 1999-11-04 SI SI9930169T patent/SI1129208T1/xx unknown
- 1999-11-04 ID IDW00200101016A patent/ID28381A/id unknown
- 1999-11-04 JP JP2000581230A patent/JP2002529477A/ja not_active Abandoned
- 1999-11-04 TR TR2001/01279T patent/TR200101279T2/xx unknown
- 1999-11-05 AR ARP990105628A patent/AR024226A1/es unknown
- 1999-11-09 US US09/436,718 patent/US6387943B1/en not_active Expired - Fee Related
-
2001
- 2001-04-19 ZA ZA200103191A patent/ZA200103191B/xx unknown
-
2002
- 2002-03-25 US US10/103,880 patent/US20020183267A1/en not_active Abandoned
- 2002-04-12 HK HK02102763.9A patent/HK1041026B/zh not_active IP Right Cessation
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