UA67795C2 - Pharmaceutical composition for treating burn wounds containing miramystine - Google Patents
Pharmaceutical composition for treating burn wounds containing miramystine Download PDFInfo
- Publication number
- UA67795C2 UA67795C2 UA2001031868A UA2001031868A UA67795C2 UA 67795 C2 UA67795 C2 UA 67795C2 UA 2001031868 A UA2001031868 A UA 2001031868A UA 2001031868 A UA2001031868 A UA 2001031868A UA 67795 C2 UA67795 C2 UA 67795C2
- Authority
- UA
- Ukraine
- Prior art keywords
- miramystine
- pharmaceutical composition
- burn wounds
- treating burn
- wounds containing
- Prior art date
Links
- 206010052428 Wound Diseases 0.000 title abstract 2
- 208000027418 Wounds and injury Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- YLGXILFCIXHCMC-JHGZEJCSSA-N methyl cellulose Chemical compound COC1C(OC)C(OC)C(COC)O[C@H]1O[C@H]1C(OC)C(OC)C(OC)OC1COC YLGXILFCIXHCMC-JHGZEJCSSA-N 0.000 abstract description 2
- 229920002678 cellulose Polymers 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- JQQZCIIDNVIQKO-UHFFFAOYSA-N benzyl-dimethyl-[3-(tetradecanoylamino)propyl]azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC1=CC=CC=C1 JQQZCIIDNVIQKO-UHFFFAOYSA-N 0.000 description 4
- 239000003349 gelling agent Substances 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 1
- 241000269435 Rana <genus> Species 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 208000024798 heartburn Diseases 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
ше Ге раниshe Ge rana
У 3-х хворих, яким пересадка була проведена без використання заявленого складу, його почали приміняти після появи ознак часткового розплавлення аутотрансплантатів, що призвело до швидкої ліквідації ГВ і збереження життєздатності лишившихся ділянок пересадженої шкіри.In 3 patients who were transplanted without using the declared composition, it was started to be used after the appearance of signs of partial melting of the autografts, which led to the rapid elimination of HV and preservation of the viability of the remaining areas of the transplanted skin.
У жодному випадку не була відмічена побічна дія складу або скарги хворих на неприємні відчуття при їх нанесенні. Навпаки, гелеподібний склад при нанесенні на ранову поверхню викликав зниження больових симптомів і відчуття печії.In no case was there a side effect of the composition or complaints of patients about unpleasant sensations when they were applied. On the contrary, the gel-like composition, when applied to the wound surface, caused a decrease in pain symptoms and a feeling of heartburn.
Як видно з табл.2. ефективність складу 1 практично не відрізняється від ефективності прототипу, що пов'язано з однаковою концентрацією мірамістину і недостатньою концентрацією гелеутворювача.As can be seen from Table 2. the effectiveness of composition 1 practically does not differ from the effectiveness of the prototype, which is associated with the same concentration of miramistin and insufficient concentration of the gelling agent.
В той же час ефективність складу 2 значно ефективніша за прототип, що при равній концентрації мірамістину підтверджує синергізм його з гелеутворювачем, який без мірамістину такого ефекту не дає (склад 8).At the same time, the effectiveness of composition 2 is much more effective than the prototype, which at an equal concentration of miramistin confirms its synergism with the gelling agent, which does not produce such an effect without miramistin (composition 8).
Заявлений склад може вироблятись фармацевтичною промисловістю тому що всі компоненти є промисловими зареєстрованими продуктами: мірамістин - реєстр. Ме 91/146/2 ентеросгель - реєстр. Ме П 98/88/6 тілоза - Сертифікат Ме РОСС ДЕ.АЯ 12.С0О 2205.The claimed composition can be produced by the pharmaceutical industry because all components are registered industrial products: miramistin - reg. Me 91/146/2 enterosgel - register. Me P 98/88/6 tylose - Certificate Me ROSS DE.AYA 12.С0О 2205.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2000116316A RU2185157C2 (en) | 2000-06-26 | 2000-06-26 | Composition for treating burn wounds |
Publications (1)
Publication Number | Publication Date |
---|---|
UA67795C2 true UA67795C2 (en) | 2004-07-15 |
Family
ID=20236630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA2001031868A UA67795C2 (en) | 2000-06-26 | 2001-03-20 | Pharmaceutical composition for treating burn wounds containing miramystine |
Country Status (3)
Country | Link |
---|---|
EA (1) | EA003935B1 (en) |
RU (1) | RU2185157C2 (en) |
UA (1) | UA67795C2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011101113A1 (en) | 2010-02-19 | 2011-08-25 | Megainpharm Gmbh | Pharmaceutical comprising myramistin |
MD481Z (en) * | 2011-08-09 | 2012-09-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Method for treating I-IIIA-degree burns |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102008039254A1 (en) | 2008-08-20 | 2010-02-25 | Megainpharm Gmbh | Medicament, useful e.g. for treating infectious- and purulent inflammatory diseases of e.g. eyes, comprises benzyl-dimethyl-(3-(myristoylamino)-propyl)-ammonium chloride, dimethyl-(3-(myristoylamino)-propyl)-amine oxide and solvent |
WO2014175757A1 (en) * | 2013-04-22 | 2014-10-30 | Общество с ограниченной ответственностью "Нанобиотех" | Antiseptic veterinary formulation and methods for use thereof |
RU2542376C1 (en) * | 2013-07-30 | 2015-02-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Agent for pyoinflammatory processes in soft tissues and mucous membranes |
-
2000
- 2000-06-26 RU RU2000116316A patent/RU2185157C2/en active
-
2001
- 2001-03-20 UA UA2001031868A patent/UA67795C2/en unknown
- 2001-06-19 EA EA200100559A patent/EA003935B1/en not_active IP Right Cessation
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011101113A1 (en) | 2010-02-19 | 2011-08-25 | Megainpharm Gmbh | Pharmaceutical comprising myramistin |
WO2011100994A1 (en) | 2010-02-19 | 2011-08-25 | Megainpharm Gmbh | Pharmaceutical comprising myramistin |
EA022283B1 (en) * | 2010-02-19 | 2015-12-30 | Мегаинфарм Гмбх | Pharmaceutical comprising benzyldimethyl[3-(myristoylamino)propyl]ammonium chloride |
MD4411C1 (en) * | 2010-02-19 | 2016-11-30 | Megainpharm Gmbh | Pharmaceutical including benzyldimethyl(3-[myristoylamino]propyl)-ammonium chloride and its use for the treatment and prevention of infectious and pyoinflammatory diseases of different etiology and localization |
MD481Z (en) * | 2011-08-09 | 2012-09-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Method for treating I-IIIA-degree burns |
Also Published As
Publication number | Publication date |
---|---|
RU2185157C2 (en) | 2002-07-20 |
EA200100559A1 (en) | 2002-02-28 |
EA003935B1 (en) | 2003-10-30 |
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