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UA114161C2 - 3-CARBOXY-4- (R)-PHENYLPYROLIDINE-2-SALT SALT AND ITS USE - Google Patents

3-CARBOXY-4- (R)-PHENYLPYROLIDINE-2-SALT SALT AND ITS USE

Info

Publication number
UA114161C2
UA114161C2 UAA201606170A UAA201606170A UA114161C2 UA 114161 C2 UA114161 C2 UA 114161C2 UA A201606170 A UAA201606170 A UA A201606170A UA A201606170 A UAA201606170 A UA A201606170A UA 114161 C2 UA114161 C2 UA 114161C2
Authority
UA
Ukraine
Prior art keywords
salt
carboxy
phenylpyrolidine
benzyloxyquinuclidine
phenylpyrrolidin
Prior art date
Application number
UAA201606170A
Other languages
Ukrainian (uk)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of UA114161C2 publication Critical patent/UA114161C2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Cпосіб одержання 3-карбокси-4-(R)-фенілпіролідин-2-ону з 3-карбокси-4-(R,S)-фенілпіролідин-2-ону, в якому за допомогою 3-(S)-бензоїлоксихінуклідину розділяють рацемічну суміш.A method of producing 3-carboxy-4- (R) -phenylpyrrolidin-2-one from 3-carboxy-4- (R, S) -phenylpyrrolidine-2-one, in which the racemic mixture is separated by 3- (S) -benzyloxyquinuclidine .

UAA201606170A 2013-12-13 2014-12-12 3-CARBOXY-4- (R)-PHENYLPYROLIDINE-2-SALT SALT AND ITS USE UA114161C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LVP-13-209A LV15015B (en) 2013-12-13 2013-12-13 Salt of 3-carboxy-4-(r)-phenylpyrrolidinone-2 and uses thereof
PCT/IB2014/066846 WO2015087291A1 (en) 2013-12-13 2014-12-12 3-carboxy-4-(r)-phenylpyrrolydine-2-one salt and its use

Publications (1)

Publication Number Publication Date
UA114161C2 true UA114161C2 (en) 2017-04-25

Family

ID=52462958

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201606170A UA114161C2 (en) 2013-12-13 2014-12-12 3-CARBOXY-4- (R)-PHENYLPYROLIDINE-2-SALT SALT AND ITS USE

Country Status (4)

Country Link
EA (1) EA027373B1 (en)
LV (1) LV15015B (en)
UA (1) UA114161C2 (en)
WO (1) WO2015087291A1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LV13635B (en) 2006-02-23 2008-01-20 Olainfarm As Enzymatic resolution of racemic 3-aryl-4-aminobutyric acids
LV13630B (en) 2006-03-16 2007-12-20 Olainfarm As Method of preparation and use of pharmaceutically active n-carbamoylmethyl-4(r)-phenyl-2-pyrrolidinone

Also Published As

Publication number Publication date
EA027373B1 (en) 2017-07-31
WO2015087291A1 (en) 2015-06-18
EA201691190A1 (en) 2016-12-30
LV15015A (en) 2015-06-20
LV15015B (en) 2015-12-20

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