UA111594C2 - Гетероциклічна сполука і її застосування - Google Patents
Гетероциклічна сполука і її застосуванняInfo
- Publication number
- UA111594C2 UA111594C2 UAA201302884A UAA201302884A UA111594C2 UA 111594 C2 UA111594 C2 UA 111594C2 UA A201302884 A UAA201302884 A UA A201302884A UA A201302884 A UAA201302884 A UA A201302884A UA 111594 C2 UA111594 C2 UA 111594C2
- Authority
- UA
- Ukraine
- Prior art keywords
- applications
- heterocyclic compound
- compound
- potentiator
- ampa
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Описується сполука, представлена формулою (І):, (I)де кожен символ є таким, як визначено в описі, або її сіль, яка є потенціатором рецептора АМРА (α-аміно-3-гідрокси-5-метил-4-ізоксазолпропіонова кислота). Сполука представленого винаходу корисна як профілактичний або терапевтичний лікарський засіб для депресії, шизофренії, хвороби Альцгеймера або гіперактивності з дефіцитом уваги (ADHD) і т. і.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010179577 | 2010-08-10 | ||
| PCT/JP2011/068497 WO2012020848A1 (en) | 2010-08-10 | 2011-08-09 | Heterocyclic compound and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA111594C2 true UA111594C2 (uk) | 2016-05-25 |
Family
ID=44534564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201302884A UA111594C2 (uk) | 2010-08-10 | 2011-09-08 | Гетероциклічна сполука і її застосування |
Country Status (39)
| Country | Link |
|---|---|
| US (11) | US9150591B2 (uk) |
| EP (1) | EP2603513B1 (uk) |
| JP (2) | JP5788496B2 (uk) |
| KR (1) | KR101852215B1 (uk) |
| CN (2) | CN104926837A (uk) |
| AR (1) | AR082618A1 (uk) |
| AU (1) | AU2011290126B2 (uk) |
| BR (1) | BR112013002250B1 (uk) |
| CA (1) | CA2807460C (uk) |
| CL (1) | CL2013000380A1 (uk) |
| CO (1) | CO6680700A2 (uk) |
| CR (1) | CR20130066A (uk) |
| CY (1) | CY1123507T1 (uk) |
| DK (1) | DK2603513T3 (uk) |
| DO (1) | DOP2013000030A (uk) |
| EA (1) | EA022078B1 (uk) |
| EC (1) | ECSP13012478A (uk) |
| ES (1) | ES2793723T3 (uk) |
| GE (1) | GEP20156216B (uk) |
| HR (1) | HRP20200844T1 (uk) |
| HU (1) | HUE049460T2 (uk) |
| IL (1) | IL224452A (uk) |
| LT (1) | LT2603513T (uk) |
| MA (1) | MA34509B1 (uk) |
| MX (1) | MX349470B (uk) |
| MY (1) | MY165908A (uk) |
| NZ (1) | NZ607593A (uk) |
| PE (1) | PE20131116A1 (uk) |
| PH (1) | PH12013500247A1 (uk) |
| PL (1) | PL2603513T3 (uk) |
| PT (1) | PT2603513T (uk) |
| RS (1) | RS60311B1 (uk) |
| SG (1) | SG187656A1 (uk) |
| SI (1) | SI2603513T1 (uk) |
| TW (1) | TWI504604B (uk) |
| UA (1) | UA111594C2 (uk) |
| UY (1) | UY33551A (uk) |
| WO (1) | WO2012020848A1 (uk) |
| ZA (1) | ZA201301120B (uk) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2603513T (pt) * | 2010-08-10 | 2020-06-08 | Takeda Pharmaceuticals Co | Composto heterocíclico e sua utilização como modulador alostérico positivo do recetor de ampa |
| US9527807B2 (en) | 2011-04-05 | 2016-12-27 | Takeda Pharmaceutical Company Limited | Sulfonamide derivative and use thereof |
| EP2813508B1 (en) * | 2012-02-08 | 2018-01-31 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use thereof |
| JP2016521755A (ja) * | 2013-06-13 | 2016-07-25 | ヴェロサイエンス，リミテッド・ライアビリティー・カンパニー | 代謝障害を治療するための組成物および方法 |
| WO2014207601A1 (en) | 2013-06-27 | 2014-12-31 | Pfizer Inc. | Heteroaromatic compounds and their use as dopamine d1 ligands |
| WO2015084796A1 (en) | 2013-12-03 | 2015-06-11 | E. I. Du Pont De Nemours And Company | Pyrrolidinones as herbicides |
| US11589583B2 (en) | 2013-12-03 | 2023-02-28 | Fmc Corporation | Pyrrolidinones herbicides |
| EP3164386B1 (en) | 2014-07-02 | 2020-10-07 | FMC Corporation | Piperidinone herbicides |
| CN107001260B (zh) | 2014-12-08 | 2020-11-10 | Fmc公司 | 3-氧基-3-(芳氨基)丙酸酯、其制备方法、以及其在制备吡咯烷酮中的用途 |
| US10405547B2 (en) | 2015-04-10 | 2019-09-10 | Fmc Corporation | Substituted cyclic amides as herbicides |
| CN107531658B (zh) | 2015-04-27 | 2021-07-27 | Fmc公司 | 作为除草剂的丁内酯 |
| NZ736055A (en) * | 2015-04-29 | 2023-05-26 | Janssen Pharmaceutica Nv | Imidazopyrazines and pyrazolopyrimidines and their use as ampa receptor modulators |
| SG11201708190UA (en) | 2015-04-29 | 2017-11-29 | Janssen Pharmaceutica Nv | Azabenzimidazoles and their use as ampa receptor modulators |
| WO2016182780A1 (en) | 2015-05-12 | 2016-11-17 | E I Du Pont De Nemours And Company | Aryl substituted bicyclic compounds as herbicides |
| US10906873B2 (en) | 2015-05-29 | 2021-02-02 | Fmc Corporation | Substituted cyclic amides as herbicides |
| RU2017142979A (ru) | 2015-06-02 | 2019-07-15 | ЭфЭмСи Корпорейшн | Замещенные циклические амиды и их применение в качестве гербицидов |
| RU2720994C2 (ru) | 2015-07-31 | 2020-05-15 | Е.И.Дюпон Де Немур Энд Компани | Новые соединения циклического n-карбоксамида, применяемые в качестве гербицидов |
| TW201713774A (zh) | 2015-08-06 | 2017-04-16 | Kohjin Life Sciences Co Ltd | 含有β-菸鹼醯胺單核苷酸的酵母萃取物及其製造方法 |
| SI3331892T1 (sl) * | 2015-08-06 | 2019-10-30 | Hoffmann La Roche | Postopki za pripravo derivatov gaINAc kisline |
| US20170181292A1 (en) * | 2015-12-16 | 2017-06-22 | Rohm And Haas Electronic Materials Llc | Method for forming organic coating on nickel surface |
| CN105669731B (zh) * | 2016-01-10 | 2017-06-30 | 沧州普瑞东方科技有限公司 | 一种4‑(4‑烷基环己氧基)苯硼酸的合成方法 |
| AU2017378640B2 (en) | 2016-12-21 | 2022-03-03 | Fmc Corporation | Nitrone herbicides |
| CN107892697B (zh) | 2016-12-26 | 2020-11-03 | 郑州泰基鸿诺医药股份有限公司 | 一种[1,3]噻嗪-2-胺类化合物及应用，药物组合物 |
| CA3057300A1 (en) | 2017-03-21 | 2018-09-27 | Fmc Corporation | Herbicidal mixture, composition and method |
| US10875838B2 (en) | 2017-03-21 | 2020-12-29 | Fmc Corporation | Pyrrolidinones and a process to prepare them |
| AR111839A1 (es) | 2017-05-30 | 2019-08-21 | Fmc Corp | Lactamas 3-sustituidas herbicidas |
| AR111967A1 (es) | 2017-05-30 | 2019-09-04 | Fmc Corp | Amidas herbicidas |
| US11447488B2 (en) | 2017-10-06 | 2022-09-20 | Takeda Pharmaceutical Company Limited | Heterocyclic compounds |
| WO2019070043A1 (ja) | 2017-10-06 | 2019-04-11 | 武田薬品工業株式会社 | 複素環化合物 |
| EP4149478A1 (en) * | 2020-05-15 | 2023-03-22 | Takeda Pharmaceutical Company Limited | Treatment for depression |
| CN113943294A (zh) * | 2020-07-15 | 2022-01-18 | 成都海博为药业有限公司 | 一种作为btk抑制剂的化合物及其制备方法与用途 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0437742Y2 (uk) | 1986-10-22 | 1992-09-04 | ||
| JPH0285851A (ja) | 1988-09-22 | 1990-03-27 | Konica Corp | 新規な写真用カプラー |
| JPH037742A (ja) | 1989-06-05 | 1991-01-14 | Toyo Tire & Rubber Co Ltd | ラバーチエーン用ゴム組成物 |
| JP2874960B2 (ja) * | 1990-06-03 | 1999-03-24 | コニカ株式会社 | 新規な染料を含有するハロゲン化銀写真感光材料 |
| JPH04119890A (ja) * | 1990-09-11 | 1992-04-21 | Konica Corp | ピラゾロチアジアジン系色素 |
| JP3430375B2 (ja) * | 1993-11-12 | 2003-07-28 | コニカ株式会社 | 感熱転写材料及び該材料に好適な色素 |
| DE19704923A1 (de) | 1997-02-10 | 1998-08-13 | Hoechst Schering Agrevo Gmbh | Klebstoffhaltige Schädlingsbekämpfungsmittel |
| AU5271900A (en) | 1999-11-04 | 2001-05-14 | Colorado State University Research Foundation | Method and device for attracting insects |
| FR2801587B1 (fr) | 1999-11-30 | 2002-01-11 | Adir | Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| WO2003031422A1 (en) * | 2001-10-10 | 2003-04-17 | Neurosearch A/S | Novel benzothiazine derivatives, their preparation and use |
| FR2833955B1 (fr) | 2001-12-21 | 2004-01-30 | Servier Lab | Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2854634B1 (fr) | 2003-05-05 | 2005-07-08 | Servier Lab | Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2865474B1 (fr) | 2004-01-26 | 2008-06-13 | Servier Lab | Nouveaux derives de benzothiazines fluorees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2879201B1 (fr) * | 2004-12-10 | 2007-02-16 | Servier Lab | Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| BRPI0713529A2 (pt) | 2006-06-23 | 2012-04-17 | Nufarm Australia Ltd | composição herbicida de fenóxi alcanoato e método de preparação e uso |
| AU2007333247B2 (en) * | 2006-12-11 | 2012-06-07 | Eli Lilly And Company | AMPA receptor potentiators |
| US20080167374A1 (en) | 2007-01-09 | 2008-07-10 | Loveland Products, Inc. | Pesticide composition and method of use |
| MX2010005028A (es) | 2007-11-05 | 2010-05-27 | Schering Corp | Moduladores de gamma secretasa. |
| AU2008345225A1 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| CA2718727A1 (en) | 2008-03-25 | 2009-10-01 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| JP2009248543A (ja) * | 2008-04-11 | 2009-10-29 | Fujifilm Corp | 光情報記録媒体および情報記録方法 |
| TW201012803A (en) * | 2008-06-06 | 2010-04-01 | Organon Nv | Heterocyclic derivatives |
| US20110257156A1 (en) | 2008-11-06 | 2011-10-20 | Zhaoning Zhu | Gamma secretase modulators |
| TW201030002A (en) | 2009-01-16 | 2010-08-16 | Bristol Myers Squibb Co | Bicyclic compounds for the reduction of beta-amyloid production |
| JP2012051806A (ja) | 2009-02-26 | 2012-03-15 | Eisai R & D Management Co Ltd | イミダゾリルピラジン誘導体 |
| FR2943342B1 (fr) | 2009-03-20 | 2011-03-04 | Servier Lab | Nouveaux derives de benzothiadiazepines,leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| WO2010140339A1 (ja) | 2009-06-01 | 2010-12-09 | 武田薬品工業株式会社 | 複素環化合物 |
| JPWO2011007756A1 (ja) | 2009-07-13 | 2012-12-27 | 武田薬品工業株式会社 | 複素環化合物及びその用途 |
| WO2011036885A1 (ja) | 2009-09-25 | 2011-03-31 | 武田薬品工業株式会社 | 複素環化合物 |
| WO2011036889A1 (ja) | 2009-09-25 | 2011-03-31 | 武田薬品工業株式会社 | 複素環化合物 |
| PT2603513T (pt) * | 2010-08-10 | 2020-06-08 | Takeda Pharmaceuticals Co | Composto heterocíclico e sua utilização como modulador alostérico positivo do recetor de ampa |
-
2011
- 2011-08-09 PT PT117499442T patent/PT2603513T/pt unknown
- 2011-08-09 NZ NZ607593A patent/NZ607593A/en unknown
- 2011-08-09 GE GEAP201113021A patent/GEP20156216B/en unknown
- 2011-08-09 KR KR1020137006113A patent/KR101852215B1/ko active IP Right Grant
- 2011-08-09 JP JP2013506362A patent/JP5788496B2/ja active Active
- 2011-08-09 PL PL11749944T patent/PL2603513T3/pl unknown
- 2011-08-09 TW TW100128311A patent/TWI504604B/zh active
- 2011-08-09 RS RS20200574A patent/RS60311B1/sr unknown
- 2011-08-09 CN CN201510259936.0A patent/CN104926837A/zh active Pending
- 2011-08-09 CA CA2807460A patent/CA2807460C/en active Active
- 2011-08-09 PE PE2013000244A patent/PE20131116A1/es active IP Right Grant
- 2011-08-09 MY MYPI2013000428A patent/MY165908A/en unknown
- 2011-08-09 AU AU2011290126A patent/AU2011290126B2/en active Active
- 2011-08-09 SG SG2013007463A patent/SG187656A1/en unknown
- 2011-08-09 SI SI201131887T patent/SI2603513T1/sl unknown
- 2011-08-09 PH PH1/2013/500247A patent/PH12013500247A1/en unknown
- 2011-08-09 LT LTEP11749944.2T patent/LT2603513T/lt unknown
- 2011-08-09 UY UY0001033551A patent/UY33551A/es not_active Application Discontinuation
- 2011-08-09 US US13/816,137 patent/US9150591B2/en active Active
- 2011-08-09 AR ARP110102905A patent/AR082618A1/es active IP Right Grant
- 2011-08-09 ES ES11749944T patent/ES2793723T3/es active Active
- 2011-08-09 MA MA35708A patent/MA34509B1/fr unknown
- 2011-08-09 MX MX2013001614A patent/MX349470B/es active IP Right Grant
- 2011-08-09 CN CN201180048970.3A patent/CN103180326B/zh active Active
- 2011-08-09 WO PCT/JP2011/068497 patent/WO2012020848A1/en active Application Filing
- 2011-08-09 EP EP11749944.2A patent/EP2603513B1/en active Active
- 2011-08-09 US US13/206,113 patent/US8575154B2/en active Active
- 2011-08-09 BR BR112013002250-7A patent/BR112013002250B1/pt active IP Right Grant
- 2011-08-09 HU HUE11749944A patent/HUE049460T2/hu unknown
- 2011-08-09 DK DK11749944.2T patent/DK2603513T3/da active
- 2011-08-09 EA EA201390222A patent/EA022078B1/ru not_active IP Right Cessation
- 2011-09-08 UA UAA201302884A patent/UA111594C2/uk unknown
-
2013
- 2013-01-28 IL IL224452A patent/IL224452A/en active IP Right Grant
- 2013-02-05 DO DO2013000030A patent/DOP2013000030A/es unknown
- 2013-02-07 CL CL2013000380A patent/CL2013000380A1/es unknown
- 2013-02-12 ZA ZA2013/01120A patent/ZA201301120B/en unknown
- 2013-02-18 CR CR20130066A patent/CR20130066A/es unknown
- 2013-02-22 US US13/774,707 patent/US8916551B2/en active Active
- 2013-02-22 US US13/774,635 patent/US8778934B2/en active Active
- 2013-03-06 EC ECSP13012478 patent/ECSP13012478A/es unknown
- 2013-03-07 CO CO13046020A patent/CO6680700A2/es active IP Right Grant
-
2014
- 2014-11-13 US US14/540,699 patent/US20150073137A1/en not_active Abandoned
-
2015
- 2015-07-21 US US14/804,935 patent/US9499568B2/en active Active
- 2015-07-29 JP JP2015149216A patent/JP6113789B2/ja active Active
-
2016
- 2016-10-10 US US15/289,650 patent/US9884875B2/en active Active
-
2017
- 2017-12-18 US US15/845,621 patent/US20180162875A1/en not_active Abandoned
-
2019
- 2019-01-24 US US16/256,773 patent/US10654874B2/en active Active
-
2020
- 2020-03-23 US US16/827,316 patent/US11279713B2/en active Active
- 2020-05-25 CY CY20201100475T patent/CY1123507T1/el unknown
- 2020-05-25 HR HRP20200844TT patent/HRP20200844T1/hr unknown
-
2024
- 2024-03-01 US US18/592,897 patent/US20240360156A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA111594C2 (uk) | Гетероциклічна сполука і її застосування | |
| WO2012137982A3 (en) | Sulfonamide derivative and use thereof | |
| CY1121549T1 (el) | Ενωσεις 1-αρυλκαρβονυλ-4-oξυ-πιπεριδινης χρησιμες για την αγωγη νευροεκφυλιστικων παθησεων | |
| UA114611C2 (uk) | Пестицидні композиції і способи, що їх стосуються | |
| UA113051C2 (xx) | Гетероциклічні похідні та їх застосування у лікуванні неврологічних розладів | |
| ECSP10010582A (es) | Derivados de aminodihidrotiazina como inhibidores de bace para el tratamiento de la enfermedad de alzheimer | |
| EA201001205A1 (ru) | Соединения, содержащие циклобутоксигруппу | |
| BR112012032244A2 (pt) | processo para preparar derivados de antranilamida com tetrazole-substituído e polimorfos cristalinos novos e derivados destes | |
| BR112015000399A2 (pt) | derivados de pirazolil pirimidina | |
| MA33939B1 (fr) | 5-alcynyl-pyrimidines | |
| MX2011005934A (es) | Compuestos organicos. | |
| EA201492023A1 (ru) | Регуляторы пути комплемента и их применение | |
| BR112012010186A2 (pt) | derivados de heteroarila contendo n como inibidores de quinase jak3. | |
| BR112014005468A2 (pt) | derivados de aminopiridina para uso como moduladores de atividade quinase | |
| CO6821935A2 (es) | Derivados novedosos de cefalosporinas y cmposiciones farmacéuticas de estos | |
| BR112012029647A2 (pt) | novos derivados de pirimidinas | |
| EA201300250A1 (ru) | Оксадиазольные ингибиторы продуцирования лейкотриена | |
| EA201200471A1 (ru) | Простые эфирные производные бициклических гетероарилов | |
| MA33948B1 (fr) | Dérivés d'acide 3-hétéroaroylamino-propionique substitues par oxygène et leur utilisation en tant qu'agents pharmaceutiques. | |
| EA201001855A1 (ru) | Соединения, содержащие циклобутоксигруппу | |
| DE602007008691D1 (de) | Cyclische sulfone, die zur verwendung als bace-inhibitoren geeignet sind | |
| EA201170606A1 (ru) | Феназопиридиновые соединения | |
| BRPI0909752B8 (pt) | processos para a produção de sulfonilpirróis como inibidores de hdac e de uma composição farmacêutica compreendendo os mesmos | |
| TN2013000034A1 (en) | Heterocyclic compound and use thereof | |
| NI201200039A (es) | Nuevos derivados dihidro - oxazolobenzodiazepinonas, su procedi |