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UA11100A - Спосіб одержаhhя феhілалкіламіhів або їх фармакологічhо прийhятhих солей - Google Patents

Спосіб одержаhhя феhілалкіламіhів або їх фармакологічhо прийhятhих солей

Info

Publication number
UA11100A
UA11100A UA4355858A UA4355858A UA11100A UA 11100 A UA11100 A UA 11100A UA 4355858 A UA4355858 A UA 4355858A UA 4355858 A UA4355858 A UA 4355858A UA 11100 A UA11100 A UA 11100A
Authority
UA
Ukraine
Prior art keywords
carbon atoms
phenyl
phenylalkylamines
preparation
general formula
Prior art date
Application number
UA4355858A
Other languages
English (en)
Russian (ru)
Inventor
Кнолл Йожеф
Шимаї Антал
Шимаи Антал
Синньєї Єва
Синньеи Ева
Шофмаі Єва
Шофмаи Ева
Тьорьок Золітан
Тьорьок Золитан
Можолітш Карой
Можолитш Карой
Бергманн Янош
Original Assignee
Хіноін Дьйодьсер Еш Ведьєсеті Термекек Д'Яра Рт
Хиноин Дьйодьсер еш Ведьєсети Термекек Д'яра РТ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Хіноін Дьйодьсер Еш Ведьєсеті Термекек Д'Яра Рт, Хиноин Дьйодьсер еш Ведьєсети Термекек Д'яра РТ filed Critical Хіноін Дьйодьсер Еш Ведьєсеті Термекек Д'Яра Рт
Publication of UA11100A publication Critical patent/UA11100A/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)

Abstract

Винахід належить до способу отримання фенілалкіламінів. При способі отримання фенілалкіламінів загальної формули де R1 - алкіл з прямим або розгалуженим ланцюгом С2-С8 фенілалкіл С7-С10, циклоалкіл С3-С8, феніл; R2 - нижчий алкіл з прямим або розгалуженим ланцюгом, нижчий алкіл, заміщений атомом галогену, гідроксидом, алкоксигрупою С1-С4 алкіл, що містить 3 атоми вуглецю і заміщений фенілом циклоалкіл С3-С8, за умови, що групи R1 і R2 разом містять від 5 до 13 атомів вуглецю, і у тому випадку, коли R1 означає етил. R2 не може означати ізобутил, або фармакологічно прийнятних солей цих сполук амін загальної формули H2N-R2 піддають взаємодії з кетоном загальної формули
UA4355858A 1986-09-25 1987-09-25 Спосіб одержаhhя феhілалкіламіhів або їх фармакологічhо прийhятhих солей UA11100A (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU864101A HU207280B (en) 1986-09-25 1986-09-25 Process for producing new phenyl-alkyl-amines and pharmaceutical compositions containing them
PCT/HU1987/000040 WO1988002254A1 (en) 1986-09-25 1987-09-25 New psychostimulant agent

Publications (1)

Publication Number Publication Date
UA11100A true UA11100A (uk) 1996-12-25

Family

ID=10966901

Family Applications (3)

Application Number Title Priority Date Filing Date
UA4742460A UA19171A (uk) 1986-09-25 1987-09-25 Спосіб одержаhhя фіhілалкіламіhів або їх фармакологічhо прийhятhих солей
UA4355858A UA11100A (uk) 1986-09-25 1987-09-25 Спосіб одержаhhя феhілалкіламіhів або їх фармакологічhо прийhятhих солей
UA4830945A UA19808A (uk) 1986-09-25 1990-09-10 Спосіб одержаhhя феhілалкіламіhів або солей цих сполук

Family Applications Before (1)

Application Number Title Priority Date Filing Date
UA4742460A UA19171A (uk) 1986-09-25 1987-09-25 Спосіб одержаhhя фіhілалкіламіhів або їх фармакологічhо прийhятhих солей

Family Applications After (1)

Application Number Title Priority Date Filing Date
UA4830945A UA19808A (uk) 1986-09-25 1990-09-10 Спосіб одержаhhя феhілалкіламіhів або солей цих сполук

Country Status (21)

Country Link
US (1) US5075338A (uk)
EP (1) EP0284621B1 (uk)
KR (1) KR880701545A (uk)
AT (1) ATE117204T1 (uk)
CS (1) CS277418B6 (uk)
DD (1) DD262226A5 (uk)
DE (1) DE3751006T2 (uk)
DK (1) DK282488A (uk)
ES (1) ES2007411A6 (uk)
FI (1) FI882474A (uk)
GE (1) GEP19960656B (uk)
HU (1) HU207280B (uk)
IL (1) IL83905A (uk)
LT (2) LT3531B (uk)
LV (2) LV10860B (uk)
PL (1) PL151642B1 (uk)
PT (1) PT85799B (uk)
RU (1) RU2007384C1 (uk)
SU (1) SU1746882A3 (uk)
UA (3) UA19171A (uk)
WO (1) WO1988002254A1 (uk)

Families Citing this family (29)

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US5430044A (en) * 1987-02-06 1995-07-04 Fisons Corporation Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties
DE68925933T2 (de) * 1988-08-12 1996-08-14 Fisons Corp Arylalkylamine und -amide mit krampflösender und nervenschützender Wirkung
US5086073A (en) * 1989-06-02 1992-02-04 John Wyeth & Brother Limited Composition for treating depression with aralkyl amines
US6001884A (en) * 1991-08-23 1999-12-14 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6011068A (en) * 1991-08-23 2000-01-04 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
HUT63579A (en) * 1991-12-20 1993-09-28 Chinoin Gyogyszer Es Vegyeszet Process for producing double-phase pharmaceutical compositions suitable for treating diseases occurring during neurodegenerative processes
ATE359259T1 (de) 1994-10-21 2007-05-15 Nps Pharma Inc Kalzium-rezeptor aktive verbindungen
US6348208B1 (en) 1995-01-13 2002-02-19 Somerset Pharmaceuticals, Inc. Methods and pharmaceutical compositions employing desmethylselegiline
US6299901B1 (en) 1995-01-13 2001-10-09 Somerset Pharmaceuticals, Inc. Methods and pharmaceutical compositions employing desmethylselegiline
US6319954B1 (en) 1995-01-13 2001-11-20 Somerset Pharmaceuticals, Inc. S-(+)-desmethylselegiline and its use in the therapeutic methods and pharmaceutical compositions
US6033682A (en) * 1995-01-13 2000-03-07 Somerset Pharmaceuticals, Inc. S(+) desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions
CA2223588C (en) * 1995-06-07 2004-01-06 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
US6316022B1 (en) 1995-06-07 2001-11-13 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
ES2326004T3 (es) 1996-05-01 2009-09-28 Nps Pharmaceuticals, Inc. Compuestos activos de receptor de ion inorganico.
EP0957080B1 (en) * 1997-08-07 2006-06-21 Fujimoto Brothers Co., Ltd. Novel ethylamine derivatives
JP4499208B2 (ja) * 1998-10-29 2010-07-07 株式会社フジモト・コーポレーション 新規な光学活性アミノペンタン誘導体
US20030119884A1 (en) * 2000-11-01 2003-06-26 Epstein Mel H. Methods and compositions for regulating memory consolidation
US20030232890A1 (en) * 2000-11-01 2003-12-18 Sention, Inc. Methods for treating an impairment in memory consolidation
WO2005000203A2 (en) 2001-10-31 2005-01-06 Sention, Inc. Methods for treating cognitive impairment and improving cognition
US20070117869A1 (en) * 2000-11-01 2007-05-24 Cognition Pharmaceuticals Llc Methods for treating coginitive impairment and improving cognition
US7619005B2 (en) * 2000-11-01 2009-11-17 Cognition Pharmaceuticals Llc Methods for treating cognitive impairment in humans with Multiple Sclerosis
CA2427388C (en) * 2000-11-01 2011-12-20 Sention, Inc. Pharmaceutical compositions and uses for improving memory and learning impairments
US20050059743A1 (en) * 2000-11-01 2005-03-17 Sention, Inc. Methods for treating mild cognitive impairment and alzheimer's disease
ATE411019T1 (de) * 2001-05-02 2008-10-15 Brni Neurosciences Inst Kohlensäureanhydrase-aktivatoren zur verbesserung der lern- und gedächtnisleistung
EP1935414A3 (en) * 2001-05-02 2010-08-18 Blanchette Rockefeller Neurosciences Institute Carbonic anhydrase activators for enhancig learning and memory
TW201207390A (en) * 2004-05-18 2012-02-16 Brni Neurosciences Inst Method for screening agent for antidepressant activity
AU2010236404B2 (en) 2009-04-15 2016-11-03 Research Triangle Institute Monoamine reuptake inhibitors
CA2968806A1 (en) 2014-12-05 2016-06-09 Semmelweis University Use of arylalkylamine monoamine oxidase inhibitors in the treatment or prevention of cancer

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US485926A (en) 1892-11-08 Field
DE767263C (de) * 1937-10-03 1952-03-31 Theodor H Temmler Verfahren zur Herstellung von ª‰-Aralkylaminen
DE893341C (de) * 1950-08-23 1953-10-15 Troponwerke Dinklage & Co Verfahren zur Herstellung von N-Aralkyl-ª‰-phenyl-isopropylaminen
US2797242A (en) * 1953-08-11 1957-06-25 Parke Davis & Co Substituted alpha-benzylphenethylamines and methods for producing the same
DE227447C (uk) 1955-03-23 1910-10-21
DE1210873B (de) * 1959-03-18 1966-02-17 Hoffmann La Roche Verfahren zur Herstellung von Halogenalkylaminen
US3044932A (en) * 1960-02-24 1962-07-17 Upjohn Co Appetite suppressant drugs
DE1133395B (de) * 1960-11-12 1962-07-19 Hoechst Ag Verfahren zur Herstellung von herz- und kreislaufwirksamen Phenylalkylaminen
DE1227447B (de) * 1962-03-30 1966-10-27 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von Phenylisopropylaminen
GB1031425A (en) * 1962-03-30 1966-06-02 Chinoin Gyogyszer Es Vegyeszet New aralkylamines and their preparation
FR1478311A (fr) * 1963-10-18 1967-04-28 Koninklijke Pharma Fab Nv Procédé de préparation d'aminoalcanes et produits en résultant
GB1218135A (en) * 1967-07-28 1971-01-06 Abbott Lab Substituted phenethylamine derivatives
DE2143204C3 (de) * 1971-08-28 1979-09-27 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt N-Fluoralkyl-phenylisopropylamin-Derivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel auf deren Basis
US4025624A (en) * 1975-11-18 1977-05-24 A. H. Robins Company, Incorporated Phenylalkylamines and phenylalkylureas in combinations to suppress gastric bleeding in aspirin therapy
US4404222A (en) * 1980-08-25 1983-09-13 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby
DD145599A1 (de) * 1979-08-23 1980-12-24 Roswitha Toepfer Mittel zur regulierung des pflanzenwachstums

Also Published As

Publication number Publication date
FI882474A0 (fi) 1988-05-25
LV10709B (en) 1995-12-20
LV10860B (en) 1996-04-20
CS277418B6 (en) 1993-03-17
GEP19960656B (en) 1996-12-24
LT3531B (en) 1995-11-27
ES2007411A6 (es) 1989-06-16
PL267913A1 (en) 1989-03-06
DE3751006T2 (de) 1995-05-24
DD262226A5 (de) 1988-11-23
US5075338A (en) 1991-12-24
PL151642B1 (en) 1990-09-28
LV10709A (lv) 1995-06-20
WO1988002254A1 (en) 1988-04-07
PT85799B (pt) 1990-08-31
DK282488D0 (da) 1988-05-24
UA19808A (uk) 1997-12-25
HUT45962A (en) 1988-09-28
EP0284621A1 (en) 1988-10-05
DE3751006D1 (de) 1995-03-02
LT3530B (en) 1995-11-27
PT85799A (en) 1987-10-01
CS689887A3 (en) 1992-08-12
SU1746882A3 (ru) 1992-07-07
ATE117204T1 (de) 1995-02-15
KR880701545A (ko) 1988-11-03
DK282488A (da) 1988-05-24
UA19171A (uk) 1997-12-25
RU2007384C1 (ru) 1994-02-15
LV10860A (lv) 1995-10-20
EP0284621B1 (en) 1995-01-18
IL83905A (en) 1993-07-08
HU207280B (en) 1993-03-29
LTIP879A (en) 1995-03-27
FI882474A (fi) 1988-05-25
LTIP878A (en) 1995-03-27

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