UA110978C2 - Azetidinylphenyl, pyridyl or pyrazinylcarboxamide derivatives as JAK inhibitors - Google Patents
Azetidinylphenyl, pyridyl or pyrazinylcarboxamide derivatives as JAK inhibitorsInfo
- Publication number
- UA110978C2 UA110978C2 UAA201400439A UAA201400439A UA110978C2 UA 110978 C2 UA110978 C2 UA 110978C2 UA A201400439 A UAA201400439 A UA A201400439A UA A201400439 A UAA201400439 A UA A201400439A UA 110978 C2 UA110978 C2 UA 110978C2
- Authority
- UA
- Ukraine
- Prior art keywords
- pyrazinylcarboxamide
- azetidinylphenyl
- pyridyl
- derivatives
- jak inhibitors
- Prior art date
Links
- -1 Azetidinylphenyl Chemical group 0.000 title abstract 2
- IPEHBUMCGVEMRF-UHFFFAOYSA-N pyrazinecarboxamide Chemical class NC(=O)C1=CN=CC=N1 IPEHBUMCGVEMRF-UHFFFAOYSA-N 0.000 title abstract 2
- 125000004076 pyridyl group Chemical group 0.000 title abstract 2
- 229940122245 Janus kinase inhibitor Drugs 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 102000015617 Janus Kinases Human genes 0.000 abstract 1
- 108010024121 Janus Kinases Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
У даному винаході представлені азетидинілфенілові, піридилові або піразинілкарбоксамідні похідні формули (1), а також їх композиції і способи їх застосування, які модулюють активність Янус-кіназ (JAK) і придатні для лікування захворювань, пов'язаних з активністю JAK, включаючи, наприклад, запальні розлади, аутоіммунні розлади, рак і інші захворювання.The present invention provides azetidinylphenyl, pyridyl or pyrazinylcarboxamide derivatives of formula (1), as well as their compositions and methods of use, which modulate Janus kinase activity (JAK) and are suitable for the treatment of diseases associated with JAK activity, including, for example, inflammatory disorders, autoimmune disorders, cancer and other diseases.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161498942P | 2011-06-20 | 2011-06-20 | |
| PCT/US2012/043099 WO2012177606A1 (en) | 2011-06-20 | 2012-06-19 | Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA110978C2 true UA110978C2 (en) | 2016-03-10 |
Family
ID=55698814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201400439A UA110978C2 (en) | 2011-06-20 | 2012-06-19 | Azetidinylphenyl, pyridyl or pyrazinylcarboxamide derivatives as JAK inhibitors |
Country Status (1)
| Country | Link |
|---|---|
| UA (1) | UA110978C2 (en) |
-
2012
- 2012-06-19 UA UAA201400439A patent/UA110978C2/en unknown
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