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UA106368C2 - 1-heterocyclyl-1,5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators - Google Patents

1-heterocyclyl-1,5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators

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Publication number
UA106368C2
UA106368C2 UAA201112305A UAA201112305A UA106368C2 UA 106368 C2 UA106368 C2 UA 106368C2 UA A201112305 A UAA201112305 A UA A201112305A UA A201112305 A UAA201112305 A UA A201112305A UA 106368 C2 UA106368 C2 UA 106368C2
Authority
UA
Ukraine
Prior art keywords
medicaments
pyrazolo
pyrimidin
heterocyclyl
dihydro
Prior art date
Application number
UAA201112305A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Риккардо Джованнини
Корнелия Дорнер-Киоссек
Кристиан Айкмайер
Деннис Фиген
Томас Фокс
Клаус Фукс
Никлас Хайне
Хольгер Розенброк
Герхард Шенцле
Original Assignee
Берингер Ингельхайм Интернациональ Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Берингер Ингельхайм Интернациональ Гмбх filed Critical Берингер Ингельхайм Интернациональ Гмбх
Priority claimed from PCT/EP2010/054050 external-priority patent/WO2010112437A1/en
Publication of UA106368C2 publication Critical patent/UA106368C2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The invention relates to novel 1,6-disubstituted pyrazolopyrimidinones of formula (I), in which is a tetrahydropyranyl-group and Ris the group V-W-*, whereby V and W independently of each other may be an aryl group or an heteroaryl group, which independently of each other may optionally be substituted. According to one aspect of the invention the new compounds are for use as medicaments or for the manufacture of medicaments, in particular medicaments for the treatment of conditions concerning deficits in perception, concentration, learning or memory. The new compounds are also for the manufacture of medicaments and/or for use in the treatment of e.g. Alzheimer's disease, in particular for cognitive impairment associated with Alzheimer's disease.
UAA201112305A 2009-03-31 2010-03-26 1-heterocyclyl-1,5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators UA106368C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
VE57409 2009-03-31
PCT/EP2010/054050 WO2010112437A1 (en) 2009-03-31 2010-03-26 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators

Publications (1)

Publication Number Publication Date
UA106368C2 true UA106368C2 (en) 2014-08-26

Family

ID=52681816

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201112305A UA106368C2 (en) 2009-03-31 2010-03-26 1-heterocyclyl-1,5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators

Country Status (1)

Country Link
UA (1) UA106368C2 (en)

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