TWM606417U - Micro tube upper cover and assembling device thereof - Google Patents

Abstract

A microtube upper cover and its assembling device are mainly used to seal the microtube upper cover in a microtube container and move it to different microtube racks for automatic biological sample preparation, analysis and inspection, and make the automatic processing process more efficient. Wherein, the microtube upper cover has a lid for sealing the microtube container, and an embedding groove for detachably connecting with a driving device; the bottom edge of the driving device is provided with a positioning portion, and A rod that can move up and down along the driving device and the positioning part for embedding in the embedding groove of the upper cover of the microtube, so that the upper cover of the microtube forms a detachable connection.

Description

Micro tube upper cover and its assembling device

This creation is related to a microtube cap and its assembling device, especially a type used to seal the cap of the microtube in a microtube container and move it to different microtube racks for automated biological sample preparation, analysis and testing, and automated processing The assembly process is more efficient.

Press; In recent years, in order to improve the consistency of inspection quality and improve the limitations of traditional manual inspection methods, medical laboratories have continuously successfully developed and implemented automated instruments and equipment in the field of molecular medicine inspection. However, the common automated biological sample processing and testing equipment on the market, especially the systems used in the field of molecular testing, usually use micro-porous disks (such as 24, 48, 96, 384 or 1536 well disks) or multi-connected testing consumables. Row microtubes have limitations in the application of automated inspection. The conventional sealed micro porous disk is covered by hot-pressing film, but this method is not easy to seal, and it is difficult to make every hole on the porous disk completely sealed. The heat vapor escapes after heating, resulting in a short reaction sample volume, resulting in experimental results The risk of misjudgment of the reading data, or the potential risk of cross-contamination due to liquid leakage between different holes. In addition, the process of detecting biological samples in the prior art is likely to cause unnecessary waste of resources. For example, the micro-porous disk is a disposable consumable. When the number of samples to be tested is low, even if there are multiple unused holes, Once used, the micro porous disc must be discarded directly, which indirectly causes a waste of resources.

In view of this, the applicant, after continuous research and experimentation, came up with the design of a microtube cover and its assembly device, which improved the shortcomings of the prior art and the defects of the automated testing equipment, thereby improving the testing efficiency.

The main purpose of this creation is to provide a microtube cap and its assembling device to seal the microtube cap in the microtube container and move it to different microtube racks for automated biological sample preparation, analysis and inspection, and avoid sealing The risk of incomplete leakage makes the automated process more efficient.

The aforementioned microtube upper cover and its assembling device are detachably connected to the microtube upper cover by a driving device, and then the microtube upper cover is covered on the microtube container, and the driving device is moved mechanically according to different needs. The microtube container connected with the upper cap of the microtube is extracted and/or moved for automated biological sample preparation and analysis, thereby avoiding the risk of leakage due to incomplete sealing.

The aforementioned microtube upper cover and its assembling device, wherein the microtube upper cover has a lid for sealing the microtube container, and an embedded groove that can be detachably connected with a driving device; the driving device The bottom edge is provided with a positioning part, and a rod that can move up and down along the driving device and the positioning part for being embedded in the embedding groove of the upper cover of the micro tube, so that the upper cover of the micro tube forms a detachable connection.

In the aforementioned microtube upper cover and its assembling device, the driving device is provided with a sliding rail, and a rod is provided on the sliding rail, so that the rod can move up and down along the sliding rail.

In the aforementioned assembly structure of the upper cover of the microtube, the slide rail of the driving device is provided with a limiting groove of an appropriate length, and the rod system is provided with a horizontal protrusion at an appropriate position and located at the wall of the limiting groove, which is equivalent to a rod When the body moves up and down along the sliding rail, the limit groove can be used to form a limit to the rod body.

The aforementioned microtube upper cover and its assembling device, wherein the positioning part provided on the driving device is sleeve-shaped, and the upper edge is provided with a locking part, which is locked into the slide rail and fixed to the bottom end of the driving device by the locking part .

The aforementioned microtube upper cover and its assembling device, wherein the microtube upper cover includes at least a cover part and a wall part extending outward from the top edge of the cover part. The inner edge of the upper cover forms an embedded groove, The rod body of the driving device extends into the embedding groove and is tightly combined with the upper cover of the micro tube.

The aforementioned microtube upper cover and its assembling device, wherein the inner edge of the upper cover of the microtube is horizontally and vertically extended outwardly to form a clamping groove, so that the opening of the microtube container can be embedded in the clamping groove tightly Cover the microtube to seal the biological sample.

Please refer to Figure 1 and Figure 2 at the same time, which are the three-dimensional exploded view and cross-sectional view of this creation. As shown in the figure, the authoring system includes a driving device 1, a microtube upper cover 2 and a microtube container 3. Among them, the driving device 1 is provided with a slide rail 11, and the slide rail 11 is provided with a rod body 12 that is driven by the driving device 1 and can move up and down along the slide rail 11. In this embodiment, the driving device 1 can be moved mechanically (the term "mechanical movement" in this specification refers to a mechanized arm module mounted on a conventional automated biological sample processing and testing equipment. The arm usually moves in a two-dimensional or three-dimensional direction in a linear manner); the slide rail 11 is provided with a limit slot 111 of an appropriate length, and the rod body 12 is provided with a horizontal protrusion at an appropriate position, and is located in the limit slot 111 The wall part 121 can be used to limit the rod body 12 by the upper and lower ends of the limit groove 111 when the rod body 12 moves up and down.

The driving device 1 is provided with a positioning portion 13 on the bottom edge of the slide rail 11. In this embodiment, the positioning portion 13 is sleeve-shaped, and its upper edge is provided with a threaded portion 131. The locking portion 131 is locked into the slide rail 11 and fixed to the bottom end of the driving device 1, so that the aforementioned rod The bottom end of 12 passes through the positioning portion 13.

The upper cap 2 of the microtube includes at least a cap 21, and a wall 22 extending horizontally and vertically from the top edge of the cap 21. The inner edge of the cap 2 forms an embedding groove 23. The diameter of the groove 23 corresponds to the diameter of the aforementioned positioning portion 13; the inner edge of the wall portion 22 forms a clamping groove 24, and the diameter of the clamping groove 24 corresponds to the diameter of the opening of the microtube container 3; The joint 21 is used to be inserted into the hole of the microtube container 3 or the microporous disk, so as to seal the biological sample to be tested in the hole of the microtube container 3 or the microporous disk. The lower end of the rod body 12 of the aforementioned driving device 1 can be extended into the embedding groove 23 and tightly combined with the upper cap 2 of the microtube. In this embodiment, the cover part 21 is transparent, and various light sources with wavelengths of 300-800nm can be introduced to excite the fluorescent substance contained in the biological sample in the tube, and at the same time, the cover part 21 can export fluorescent light to For optical detection.

The diameter of the opening of the microtube container 3 is equivalent to the diameter of the clamp groove 24 of the upper cover 2 of the fixed microtube, which is used for accommodating such as blood, body fluid, animal tissue, plant tissue, virus, free nucleic acid, and eukaryotic or A biological sample of prokaryotic cells waiting to be tested.

With the aforementioned components, the mechanical moving drive device 1 can be used to extract and or move the microtube container 3 connected to the microtube upper cover 2 according to different requirements for automated biological sample preparation analysis and inspection, avoiding the risk of leakage due to incomplete sealing.

Please refer to Figure 3, which is a three-dimensional view of the micro tube top cover placed on the micro multi-well plate. As shown in the figure, the operating example of this creation is to place a plurality of microtube upper caps 2 on the microporous disk 4 respectively.

Please refer to Figures 4 and 5 at the same time, which are the three-dimensional and cross-sectional views of the driving device connected to the upper cap of the microtube. As shown in the figure, the rod body 12 of the driving device 1 of this creation is inserted into the embedding groove 23 of the upper cap 2 of the micro tube, so that the upper cap 2 of the micro tube is engaged with the lower end of the rod body 12, and the upper edge of the rod is supported The positioning part 13 at the bottom end of the driving device 1 is moved mechanically to extract the upper cap 2 of the microtube and move it to the top of the target microtube container.

Please refer to Figure 6 and Figure 7 at the same time, which are the three-dimensional and cross-sectional views of the microtube cover connected to the microtube container. Please refer to Figure 2. As shown in the figure, this creation is created after the rod 12 of the driving device 1 engages the upper cap 2 of the microtube and moves to the top of the microtube container 3 on the target microtube rack 5, and then through the driving device 1 Snap the upper cap 2 of the microtube to the container 3 of the microtube downward. Among them, since the inner edge of the wall portion 22 of the microtube upper cover 2 is a clamping groove 24, the opening of the microtube container 3 can be inserted into the clamping groove 24 and tightly connected to the microtube upper cover 2, thereby sealing The biological sample.

Please refer to Figure 8 and Figure 9 at the same time, in conjunction with Figure 10, which is the moving state diagram of this creation, as well as the three-dimensional and cross-sectional view of placing the microtube container on the microtube rack. As shown in the figure, after the cap 2 of the micro tube is covered, the mechanical movement of this invention directly extracts the micro tube container 3 tightly combined with the micro tube cap 2, and removes the micro tube container 3 from the micro tube through the mechanical movement. The rack 5 is moved to another microtube rack 5a. In this way, the author can execute the upper cover and the moving steps at the same time in a single mechanical movement, simplifying the tedious steps and mechanical settings, making the automated processing more efficient, and reducing the development cost of automated instruments.

Please refer to Figure 11 and Figure 12 at the same time, and in conjunction with Figure 13, is the action diagram of removing the upper cap of the microtube, as well as the three-dimensional view and cross-sectional view of removing the upper cap of the microtube according to this invention. As shown in the figure, this creation is based on the aforementioned movement of the microtube container 3 from the microtube rack 4 to another microtube rack 5a, the driving device 1 drives the rod body 12 to move upwards, because the upper edge of the microtube cover 2 is Hold the positioning part 13 at the bottom end of the driving device 1. When the rod body 12 moves upward, its lower end will be separated from the upper cap 2 of the micro tube. The upper cap 2 of the micro tube is removed, and finally the micro tube container 3 is left in the micro tube. On the tube stand 5a for subsequent testing steps.

Please refer to FIG. 14, which is a perspective view of another operation embodiment of this creation. As shown in the figure, another operating embodiment of this creation, in which the driving device 1 and the upper cap 2 of the microtube have the same way of removing and upper caps as described above. I will not repeat them here. The only difference in this embodiment is that the microtube container 3 is changed to micro porous plate 4. The micro porous disc 4 is a disc-shaped structure and is provided with a plurality of micro holes for loading the biological samples. The driving device 1 of this invention can also directly cover the microtube upper cover 2 on the micropores of the microporous disk and closely integrate with it. Furthermore, by the movement of the driving device 1, the micro-porous disk 4 tightly integrated with the upper cap 2 of the micro-tube can be directly extracted, and the micro-porous disk 4 can be moved to a specific position as needed.

The foregoing embodiments are merely illustrative of the preferred implementation of this creation, rather than limiting the scope of this creation. All minor modifications and changes will still not lose the essence of this creation, nor deviate from the spirit of this creation.

In summary, this creation uses a drive device with a positioning part on the bottom edge, a rod that can move up and down on the drive device, and a microtube upper cover that is detachably connected to the rod to form a microtube upper cover And its assembly device. It is used to seal the upper cap of the microtube to the microtube container and move it to different microtube racks for automated biological sample preparation and analysis, avoiding the risk of leakage due to incomplete sealing and making the automated processing more efficient. For a practical design, it is truly a creation of novelty. I filed an application for a patent in accordance with the law. I pray that the Bureau will review it and grant the patent as soon as possible.

1: drive device 11: Slide rail 111: limit slot 12: Rod body 121: Kakibe 13: Positioning department 131: Screw part 2: upper cover 21: cover part 22: Gakibe 23: Embedded slot 24: Clamping groove 3: Micro tube container 4: Micro porous plate 5: Micro tube rack 5a: Micro tube rack

Figure 1 is a three-dimensional exploded view of this creation.

Figure 2 is a cross-sectional view of this creation.

Figure 3 is a three-dimensional view of the micro tube top cover placed on the micro multi-well plate.

Figure 4 is a three-dimensional view of the driving device connected to the upper cap of the microtube.

Figure 5 is a cross-sectional view of the driving device connected to the upper cap of the microtube of the present invention.

Figure 6 is a three-dimensional view of the microtube upper cover connected to the microtube container of this creation.

Figure 7 is a cross-sectional view of the microtube upper cover connected to the microtube container of this invention.

Figure 8 is the movement state diagram of this creation.

Figure 9 is a three-dimensional view of the microtube container placed in the microtube rack in this creation.

Figure 10 is a cross-sectional view of this creation with the microtube container placed in the microtube rack.

Figure 11 is a diagram of the removal of the upper cover of the microtube of this creation.

Figure 12 is a perspective view of the removal of the upper cap of the microtube in this creation. Figure 13 is a cross-sectional view of the disassembly of the upper cap of the microtube in this creation. Fig. 14 is a three-dimensional view of another operation embodiment of this creation; Fig. 1 is a three-dimensional view of this creation.

1: drive device

11: Slide rail

111: limit slot

12: Rod body

121: Kakibe

13: Positioning department

131: Screw part

2: upper cover

21: cover part

22: Gakibe

23: Embedded slot

24: Clamping groove

3: Micro tube container

Claims (6)

A microtube upper cover and its assembling device include at least a microtube upper cover and a driving device, wherein the microtube upper cover has a cap for sealing the microtube container, and a device that can be formed with a driving device Removably connected embedding groove; the driving device is provided with a positioning part, and a rod that can move up or down along the driving device and the positioning part for being embedded in the embedding groove of the upper cover of the microtube, The upper cover of the micro tube forms a detachable connection. The assembling structure of the microtube upper cover according to claim 1, wherein the driving device is provided with a sliding rail, and a rod is provided on the sliding rail, so that the rod can move up or down along the sliding rail. The microtube upper cover and its assembling device according to claim 1, wherein the slide rail of the driving device is provided with a limit slot of an appropriate length, and the rod system is provided with a horizontal protrusion at an appropriate position and is located at the limit The wall part of the groove can be used to limit the position of the rod body by the limit groove when the rod body moves up and down along the slide rail. The microtube upper cover and its assembling device according to claim 1, wherein the positioning part provided on the driving device is sleeve-shaped, and the upper edge is provided with a locking part, and the locking part is locked into the The sliding rail is fixed at the bottom end of the driving device. The microtube upper cap and its assembling device according to claim 1, wherein the top edge of the cap of the microtube upper cap extends horizontally and vertically outward to form a clamping groove, so that the opening of the microtube container is exactly It can be embedded in the clamping groove and tightly combined with the upper cover of the micro tube. The microtube upper cap and the assembling device thereof according to claim 1, wherein the cap of the microtube upper cap is transparent.

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