TWI854148B - Contact lens and contact lens product - Google Patents

Abstract

A contact lens includes an optical zone and at least one light-blocking annular zone, wherein the light-blocking annular zone is disposed around a center point of the contact lens. When the specific condition is satisfied, excessive lights penetrating therethrough can be avoided meanwhile the lights penetrating therethrough are sufficient, which can ease the photophobia problem and can further eliminate peripheral aberrations, so that the clarity and sharpness of the image of the field of view can be enhanced.

Description

Contact Lenses and Contact Lens Products

The present invention relates to a contact lens and a contact lens product, and in particular to a contact lens and a contact lens product capable of controlling light flux and improving imaging quality.

Eyes are the windows to the soul. However, due to congenital defects or improper use, the proportion of people with abnormal vision is gradually increasing. Common vision problems include myopia, hyperopia or astigmatism. Myopia patients have a strong corneal refractive power, which causes the image to focus in front of the retina. Hyperopia patients have a weak corneal refractive power, which causes the image to focus behind the retina. Astigmatism patients have uneven curvature of the corneal surface in different areas or uneven corneal surface, which makes it impossible for light to focus accurately on the retina to form a clear image.

In order to correct the aforementioned vision problems, patients generally wear glasses with frames or contact lenses. Glasses with frames are not conducive to outdoor activities and affect the aesthetics, so the number of contact lens wearers is gradually increasing.

However, the effect of using contact lenses to control light flux is not satisfactory. Too much light flux can easily lead to photophobia, while too little light flux will cause the image to be dark and unclear. Therefore, how to improve the structure and/or material of contact lenses to effectively control light flux, that is, on the one hand, to prevent too much light from entering the eyes and avoid photophobia, and on the other hand, to maintain sufficient light flux to ensure the brightness of the image, has become the goal of relevant industry practitioners and scholars.

One object of the present invention is to provide a contact lens comprising a light-blocking annular zone, thereby preventing excessive light from entering and taking into account sufficient light throughput, thereby alleviating the problem of photophobia, and further eliminating peripheral aberrations, thereby improving the clarity and sharpness of images within the field of vision.

According to the present invention, a contact lens is provided, comprising an optical zone and at least one light-blocking annular zone, the light-blocking annular zone being arranged around the center point of the contact lens. The light-blocking annular zone comprises at least two light-blocking portions, the two light-blocking portions are respectively a first light-blocking portion and a second light-blocking portion from the inside to the outside, and there is a gap between the first light-blocking portion and the second light-blocking portion.

According to the present invention, a contact lens product is provided, comprising the contact lens described in the previous paragraph and an immersion solution, wherein the contact lens is immersed in the immersion solution. At least one of the contact lens and the immersion solution contains a ciliary muscle paralytic.

FIG. 1A is a schematic diagram showing a contact lens 10 according to an embodiment of the present invention. In FIG. 1A , the contact lens 10 includes an optical area 11 and a light-blocking annular area 12 , and the light-blocking annular area 12 is disposed around a center point O of the contact lens 10 .

Specifically, in FIG. 1A , the optical zone 11 refers to the area enclosed by the dotted line, and the light-blocking annular area 12 refers to the area at the sprinkler point. In this embodiment, the optical zone 11 and the light-blocking annular area 12 partially overlap, but in other embodiments, the optical zone 11 and the light-blocking annular area 12 may be completely staggered. In addition, the light-blocking annular area 12 may be concentric with the contact lens 10, or the light-blocking annular area 12 may not be concentric with the contact lens 10.

The average transmittance of the light-blocking annular region 12 in visible light (400 nm~700 nm) is Tavg, which satisfies the following conditions: 0% ＜ Tavg ≤ 60%. In this way, excessive light can be prevented from entering and sufficient luminous flux can be taken into account, thereby alleviating the problem of photophobia, and further eliminating peripheral aberrations, thereby improving the clarity and sharpness of the image within the field of vision. Alternatively, it can meet the following conditions: 0% ＜ Tavg ≤ 50%. Alternatively, it can meet the following conditions: 1% ＜ Tavg ≤ 50%. Alternatively, it can meet the following conditions: 0% ＜ Tavg ≤ 40%. Alternatively, it can meet the following conditions: 5% ＜ Tavg ≤ 40%. Alternatively, it can meet the following conditions: 0% ＜ Tavg ≤ 30%. Alternatively, it may satisfy the following conditions: 10% < Tavg ≤ 30%. Alternatively, it may satisfy the following conditions: 0% < Tavg ≤ 20%. Alternatively, it may satisfy the following conditions: 10% < Tavg ≤ 20%. Alternatively, it may satisfy the following conditions: 0% < Tavg ≤ 10%.

The minimum diameter of the light-blocking annular area 12 is CDmin, and the maximum diameter of the contact lens 10 is D, which satisfies the following conditions: 0.01 ≤ CDmin/D ≤ 0.80. In this way, excessive light can be prevented from entering while sufficient light flux can be taken into account, thereby alleviating the problem of photophobia, and further eliminating peripheral aberrations, thereby improving the clarity and sharpness of the image within the field of vision. Alternatively, it can meet the following conditions: 0.01 ≤ CDmin/D ≤ 0.45. Alternatively, it can meet the following conditions: 0.05 ≤ CDmin/D ≤ 0.45. Alternatively, it can meet the following conditions: 0.10 ≤ CDmin/D ≤ 0.40. Alternatively, it may satisfy the following condition: 0.20 ≤ CDmin/D ≤ 0.40.

The light-blocking annular area 12 may include at least two light-blocking parts (see FIG. 4 ), and different light-blocking parts may have gaps between them or be designed to be closely connected. In this way, the amount of visible light passing through can be further reduced, thereby enhancing the effect of reducing photophobia.

The average transmittance of the multiple light-blocking parts of the light-blocking annular region 12 in visible light can be changed in a gradient manner, that is, different light-blocking parts can have different color depth change designs, and the color can be designed to be dark to light from the inside to the outside (Tavg1<Tavg2, where Tavg1 and Tavg2 are the average transmittance of the first light-blocking part and the second light-blocking part from the inside to the outside in visible light, respectively), or can be designed to be light to dark (Tavg 1＞Tavg2), if there are more light-blocking parts, it can be further designed from deep to shallow and then to deep (Tavg1＜Tavg2 and Tavg3＜Tavg2, where Tavg1, Tavg2, and Tavg3 are the average transmittance of the first light-blocking part, the second light-blocking part, and the third light-blocking part from the inside to the outside in visible light, respectively), or it can be a wave-like color depth gradient change from shallow to deep and then to shallow (Tavg1＞Tavg2 and Tavg3＞Tavg2). In this way, the effect of blocking visible light can be effectively changed and controlled, and the blocking range can be strengthened according to needs with a gradient design while taking into account the visual aesthetic effect.

The light-blocking portion of the light-blocking annular area may further include a plurality of micro light-blocking portions (see FIG. 15 ), which may be arranged in a radial manner, and the average transmittance of the micro light-blocking portions in visible light may change gradually, that is, different micro light-blocking portions may have different color depth changes along the clockwise direction or the counterclockwise direction. In this way, the visual aesthetic effect can be enhanced and the rotation positioning recognition function can be provided.

The maximum diameter of the light-blocking annular area 12 is CDmax, and the minimum diameter of the light-blocking annular area 12 is CDmin, which can meet the following conditions: 0.5 mm ≤ CDmax-CDmin ≤ 13.0 mm. Thus, the size of the light-blocking annular area 12 is appropriate, which helps to improve visual comfort and meet aesthetic requirements. Alternatively, it can meet the following conditions: 1.0 mm ≤ CDmax-CDmin ≤ 12.0 mm. Alternatively, it can meet the following conditions: 1.5 mm ≤ CDmax-CDmin ≤ 11.0 mm. Alternatively, it can meet the following conditions: 2.0 mm ≤ CDmax-CDmin ≤ 10.0 mm. Alternatively, it can meet the following conditions: 3.0 mm ≤ CDmax-CDmin ≤ 9.0 mm. Alternatively, it may meet the following conditions: 3.0 mm ≤ CDmax-CDmin ≤ 8.0 mm.

The minimum diameter of the light-blocking annular area 12 is CDmin, and the maximum diameter of the optical area 11 is OD, which can meet the following conditions: 0.05 ≤ CDmin/OD ≤ 2.0. This helps maintain an appropriate amount of light input and ensures a visual imaging effect with moderate brightness. Alternatively, it can meet the following conditions: 0.10 ≤ CDmin/OD ≤ 1.80. Alternatively, it can meet the following conditions: 0.15 ≤ CDmin/OD ≤ 1.60. Alternatively, it can meet the following conditions: 0.15 ≤ CDmin/OD ≤ 1.40. Alternatively, it can meet the following conditions: 0.20 ≤ CDmin/OD ≤ 1.00. Alternatively, it can meet the following conditions: 0.20 ≤ CDmin/OD ≤ 0.85.

In this embodiment, the inner periphery 12A of the light-blocking annular area 12 is circular, and in other embodiments, the inner periphery 12A of the light-blocking annular area 12 may be a polygon with at least four sides (see FIGS. 7 to 10 ). In this way, the design can be diversified according to consumer needs to avoid monotonous patterns, and can also provide rotational stability direction confirmation and identification of astigmatism correction, presbyopia correction or multi-focal lenses.

The contact lens 10 may include photochromic materials, thereby reducing the irritation and damage to the eyes caused by strong light in an outdoor strong light environment, and enhancing the visible light blocking effect of the light-blocking annular area 12, thereby improving the applicability of the lens in an environment with drastic changes in light intensity.

The photochromic material refers to a substance (A) that undergoes a chemical reaction and transforms into another substance (B) when exposed to light of a certain wavelength, and the generated another substance (B) undergoes a reversible chemical reaction under the action of light or heat and returns to the original substance (A), and the absorption spectra of the original substance (A) and the another substance (B) are different and present different colors. Specifically, the photochromic material can be, but is not limited to, spiropyrans, spirooxazines, benzo and naphthopyrans, fulgides, diarylethenes, or a combination thereof. The aforementioned "combination thereof" means that the photochromic material may include at least two of spiropyran compounds, spiro-1,4-oxadiazine compounds, naphthopyran compounds, fulgide compounds, and diarylethene compounds, and they may be mixed in any proportion. For example, the spiropyran compound may be, but is not limited to, 1',3'-dihydro-1',3',3'-trimethyl-6-nitrospiro[2H-1-benzopyran-2,2'-(2H)-indole] (1′,3′-dihydro-1′,3′,3′-trimethyl-6-nitrospiro[2H-1-benzopyran-2,2′-(2H)-indole]; CAS number: 1498-88-0) or 1′,3′-dihydro-8-methoxy-1′,3′,3′-trimethyl-6-nitrospiro[2H-1-benzopyran-2,2′-(2H)-indole] (1′,3′-dihydro-8-methoxy-1′,3′,3′-trimethyl-6-nitrospiro[2H-1-benzopyran-2,2′-(2H)-indole]; CAS number: 1498-89-1). The spiro-1,4-oxazine compound may be, but is not limited to, 1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3′-[3H]naphth[2,1-b][1,4]oxazine] (CAS No. 27333-47-7) or 5-chloro-1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3′-[3H]naphth[2,1-b][1,4]oxazine] (CAS No. 27333-47-7). chloro-1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3′-(3H)naphth[2,1-b](1,4)oxazine]; CAS number is 27333-50-2) or 1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3′-[3H]phenanthro[9,10-b](1,4)oxazine] (1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3′-[3H]phenanthro[9,10-b](1,4)oxazine]; CAS number is 119980-36-8). The naphthopyran compound may be, but is not limited to, hydroxy-4-methyl-2H-naphtho(1,2-B)pyran-2-one (CAS No. 21353-16-2). The fulgide compound may be, but is not limited to, (E)-benzylidene (diphenylmethylene) succinic anhydride (CAS No. 37460-01-8) or 3-[(E)-2-(2,5-dimethylfuran-3-yl)ethylidene]dihydro-4-(1-methylethylidene)-2,5-furandione (CAS No. 77515-04-9). The diarylethene compound may be, but is not limited to, 9,10-dihydrophenanthrene (CAS No. 776-35-2).

Specifically, at least one of the optical zone 11 and the light-blocking annular zone 12 may include a photochromic material, that is, only the optical zone 11 may include a photochromic material, or only the light-blocking annular zone 12 may include a photochromic material, or both the optical zone 11 and the light-blocking annular zone 12 may include a photochromic material. When the optical zone 11 includes a photochromic material, the contact lens 10 can function like sunglasses in an outdoor environment with strong light, reducing the irritation and damage to the eyes caused by strong light. When the light-blocking annular zone 12 includes a photochromic material, the visible light blocking effect of the light-blocking annular zone 12 can be enhanced, and the contact lens can be effectively used indoors or outdoors, and the applicability to environments with drastic changes in light intensity is improved.

More specifically, the photochromic material can be added to the composition of the contact lens 10, so that the entire contact lens 10 has a photochromic effect. Alternatively, the photochromic material may be added only to a part of the contact lens 10. For example, the contact lens 10 may be a double-film contact lens made by a sandwich process. The double-film contact lens includes two main structures, an object side layer (not disclosed in the figure) and an image side layer (not disclosed in the figure), and the object side layer and the image side layer have a color film (not disclosed in the figure). The color film can be formed on the surface of the object side layer and the image side layer by printing, evaporation, coating, etc., and the color film can be formed on specific areas on the surface of the object side layer and the image side layer and can have different pattern changes. In this case, the photochromic material is added only to a part of the contact lens 10. For example, the contact lens 10 may be a double-film contact lens made by a sandwich process. The double-film contact lens includes two main structures, an object side layer (not disclosed in the figure) and an image side layer (not disclosed in the figure), and the object side layer and the image side layer have a color film (not disclosed in the figure). The color film can be formed on the surface of the object side layer and the image side layer by printing, evaporation, coating, etc., and the color film can be formed on specific areas on the surface of the object side layer and the image side layer and can have different pattern changes. The color-changing material can be added to the object side layer and/or the image side layer. For example, it can be mixed in the composition of the object side layer and/or the image side layer so that the object side layer and/or the image side layer as a whole have a photochromic effect. Alternatively, the photochromic material can be formed on the surface of the object side layer and/or the image side layer by printing, evaporation, coating, etc. (partial or complete coverage can be possible). Alternatively, the photochromic material can be added to the color pigment that forms the color film, becoming a part of the color film and forming a specific area on the surface of the object side layer and the image side layer and having different pattern changes.

The contact lens 10 may be made of silicone hydrogel, and the composition for preparing the silicone hydrogel may include at least three monomers, which may be 2-hydroxyethyl methacrylate, methacrylic acid, glycerol monomethacrylate, N-vinyl-2-pyrrolidinone, N,N-dimethyl acrylamide, 3-methacryloyloxypropyltris (trimethylsilyloxy) silane, (3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsilyloxy)methyl (trimethylsiloxy) methylsilane), (3-acryloxy-2-hydroxypropoxypropyl) terminated polydimethylsiloxane or methyl methacrylate, that is, at least three of the above monomers can be selected as monomer components in the preparation of the silicone hydrogel composition. The other components of the silicone hydrogel composition are commonly used and will not be described in detail. In this way, the contact lens 10 has a better oxygen permeability and can provide a comfortable feeling for long-term wearing.

The material of the contact lens 10 may be hydrogel, and the composition for preparing the hydrogel may include at least two monomers, which may be hydroxyethyl methacrylate, methacrylic acid, 2-methyl-2-acrylate-2,3-dihydroxypropyl ester, N-vinyl-2-pyrrolidone, N,N-dimethylacrylamide, methacryloxypropyl tris(trimethylsiloxyalkyl)silane, (3-methacryloxy-2-hydroxypropoxy)propyl bis(trimethylsiloxy)methyl, 3-acetoxy-2-hydroxypropoxypropyl terminated polydimethylsiloxane or methyl methacrylate. In other words, at least two of the aforementioned monomers may be selected as monomer components in preparing the hydrogel composition. The other components of the hydrogel composition are conventional and will not be described in detail herein. Thus, the contact lens 10 has a better water content and comfort, which can maintain the moist, smooth, soft and comfortable moisture feeling of the contact lens 10 and avoid the foreign body sensation when worn.

The contact lens 10 can be a multi-focal contact lens, thereby being helpful for correcting astigmatism, presbyopia, myopia and hyperopia. When applied to correct myopia, it can further provide a vision control effect of alleviating myopia.

The maximum diameter of the light-blocking annular zone 12 is CDmax, and the maximum diameter of the contact lens 10 is D, which can meet the following conditions: 0.5 ≤ CDmax/D ≤ 1.0. In this way, the light-blocking annular zone 12 can produce an effect of increasing the pupil area in an outdoor environment and reduce the damage caused by strong light outdoors. Alternatively, it can meet the following conditions: 0.55 ≤ CDmax/D ≤ 1.00. Alternatively, it can meet the following conditions: 0.65 ≤ CDmax/D ≤ 1.00. Alternatively, it can meet the following conditions: 0.75 ≤ CDmax/D ≤ 1.00. Alternatively, it can meet the following conditions: 0.80 ≤ CDmax/D ≤ 0.95.

Please refer to FIG. 1B, which is a schematic side view of the contact lens 10 in FIG. 1A. In FIG. 1B, the base curve of the contact lens 10 is BC, which can meet the following conditions: 9.00 mm ≤ BC. In this way, the contact lens 10 can provide a base curve with a larger radius of curvature, which helps to fit the flatter cornea, thereby improving the wearing comfort and fit. For example, for patients who have undergone laser corneal surgery, since the cornea is flatter after surgery, the base curve of general contact lenses cannot achieve effective comfort and complete fit. Therefore, the contact lens 10 of the present invention is conducive to wearing by patients who have undergone laser corneal surgery. Alternatively, it may satisfy the following conditions: 9.25mm ≤ BC. Alternatively, it may satisfy the following conditions: 9.50mm ≤ BC. Alternatively, it may satisfy the following conditions: 9.75mm ≤ BC. Alternatively, it may satisfy the following conditions: 10.00mm ≤ BC ≤ 100.00mm.

Specifically, the base curve refers to the curvature of the rear surface (not separately labeled) of the contact lens 10 close to the cornea. The larger the base curve, the flatter the rear surface of the contact lens 10. When the base curve of the contact lens 10 is larger than the base curve of the eyeball, the contact lens 10 cannot be attached to the surface of the eyeball and is prone to displacement. On the contrary, when the base curve of the contact lens 10 is smaller than the base curve of the eyeball, it is easy to cause excessive tension and discomfort. Therefore, when the base curve of the contact lens 10 is greatly different from the base curve of the eyeball, it is easy to cause vision fluctuations or the contact lens 10 to fall off, and even cause corneal infection. Generally, the base curve of the contact lens 10 is designed to be about 0.4 mm larger than the base curve of the cornea. The base curve of the eyeball of the Chinese is about 8.4 mm to 8.6 mm, so the base curve of the contact lens currently on the market is mostly designed to be less than 9 mm, which is not suitable for patients with myopia who have a flatter cornea after laser surgery.

FIG. 2 is a schematic diagram showing a contact lens product 30 according to another embodiment of the present invention. In FIG. 2, the contact lens product 30 includes a contact lens 10 and an immersion solution 20. The contact lens 10 is immersed in the immersion solution 20. For details of the contact lens 10, please refer to the above text and will not be described here. The immersion solution 20 can be a solution used for immersing and preserving contact lenses on the market.

At least one of the contact lens 10 and the soaking solution 20 may contain a ciliary muscle anesthetic. That is, only the contact lens 10 may contain a ciliary muscle anesthetic, or only the soaking solution 20 may contain a ciliary muscle anesthetic, or both the contact lens 10 and the soaking solution 20 may contain a ciliary muscle anesthetic. Thus, the contact lens 10 of the present invention can improve the problem of peripheral aberration and image blur caused by pupil dilation caused by ciliary muscle paralyzers when using ciliary muscle paralyzers. Since the effect of ciliary muscle paralyzers can dilate the pupil to 2 to 4 times the original normal pupil size, the dilated pupil allows too much light from the peripheral area to enter the eye, which obviously interferes and generates aberrations in the periphery. Therefore, the contact lens 10 of the present invention can block excessive light from entering and take into account sufficient light flux to avoid serious photophobia problems, further effectively eliminate peripheral aberrations, and ensure that the clarity and sharpness of the image within the field of vision are maintained.

Specifically, a ciliary muscle anesthetic may be added to the composition for preparing the contact lens 10, so that the final contact lens 10 contains the ciliary muscle anesthetic. Thus, when the contact lens 10 is worn, the ciliary muscle anesthetic may be slowly released, which helps to delay the effect of myopia. The treatment procedure is simplified so that the patient can have the vision control function by simply wearing the contact lens 10. Alternatively, a ciliary muscle anesthetic may be added to the solution for soaking and storing contact lenses on the market, so that the immersion solution 20 contains the ciliary muscle anesthetic, thereby the ciliary muscle anesthetic can take effect when the contact lens 10 is worn, effectively exerting an immediate effect and having the function of simplifying the treatment procedure. The weight percentage concentration of the ciliary muscle anesthetic in the contact lens 10 or in the immersion solution 20 is ConA, which can meet the following conditions: 0% < ConA ≤ 1%. Alternatively, it can meet the following conditions: 0% < ConA ≤ 0.5%. Alternatively, it can meet the following conditions: 0% < ConA ≤ 0.25%. Alternatively, it can meet the following conditions: 0% < ConA ≤ 0.1%. Alternatively, it may satisfy the following conditions: 0% < ConA ≤ 0.05%. Alternatively, it may satisfy the following conditions: 0% < ConA ≤ 0.01%.

Based on the above description, specific embodiments are presented below and described in detail with reference to the drawings.

<Example 1>

FIG. 3 is a schematic diagram showing a contact lens 100 according to Embodiment 1 of the present invention. In FIG. 3, the contact lens 100 includes an optical zone 110 and a light-blocking annular zone 120. The light-blocking annular zone 120 is disposed around the center point O of the contact lens 100, and the inner periphery 120A of the light-blocking annular zone 120 is circular. The optical zone 110 is the area enclosed by the dotted line. In Embodiment 1, the optical zone 110 and the light-blocking annular zone 120 partially overlap.

In Example 1, the minimum diameter of the light-blocking annular area 120 is CDmin, the maximum diameter of the light-blocking annular area 120 is CDmax, the maximum diameter of the optical area 110 is OD, the maximum diameter of the contact lens 100 is D, and the base curve of the contact lens 100 is BC (refer to FIG. 1A ). The numerical values of parameters such as CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, and BC of Example 1 are recorded in Table 1. Table 1 CDmin (mm) 5.00 CDmax/D 1.00 CDmax (mm) 13.50 CDmax-CDmin (mm) 8.50 OD (mm) 5.50 CDmin/OD 0.91 D (mm) 13.50 BC (mm) 8.00 CDmin/D 0.37

The contact lens 100 is made of hydrogel, and the composition for preparing the hydrogel includes the following monomers: hydroxyethyl methacrylate, methacrylic acid, 2-methyl-2-acrylate-2,3-dihydroxypropyl ester, and N-vinyl-2-pyrrolidone. The contact lens 100 is a single-focus contact lens.

The average transmittance of the light-blocking annular region 120 to visible light is Tavg, and the values thereof before and after being irradiated with light in the wavelength range of 200nm-400nm for 10 seconds are shown in Table 2. Table 2 Tavg before irradiation (%) 8 After irradiation Tavg (%) 8

<Example 2>

FIG. 4 is a schematic diagram of a contact lens 200 according to Embodiment 2 of the present invention. In FIG. 4, the contact lens 200 includes an optical zone 210 and a light-blocking annular zone 220. The light-blocking annular zone 220 is arranged around the center point O of the contact lens 200, and the inner periphery 220A of the light-blocking annular zone 220 is circular. Specifically, the light-blocking annular zone 220 includes four unconnected light-blocking portions, namely a first light-blocking portion 221, a second light-blocking portion 222, a third light-blocking portion 223, and a fourth light-blocking portion 224. The optical zone 210 is the area enclosed by the dotted line. In Embodiment 2, the optical zone 210 and the light-blocking annular zone 220 partially overlap.

The numerical values of parameters such as CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, and BC of Example 2 are recorded in Table 3. Please refer to Example 1 for the definitions of the aforementioned parameters. Table 3 CDmin (mm) 6.00 CDmax/D 0.93 CDmax (mm) 13.00 CDmax-CDmin (mm) 7.00 OD (mm) 7.50 CDmin/OD 0.80 D (mm) 14.00 BC (mm) 8.75 CDmin/D 0.43

The contact lens 200 is made of hydrogel, and the composition for preparing the hydrogel includes the following monomers: hydroxyethyl methacrylate, methacrylic acid, and 2-methyl-2-acrylate-2,3-dihydroxypropyl ester. The contact lens 200 is a single-focus contact lens.

The average transmittance of the light-blocking annular region 220 to visible light is Tavg, and the values thereof before and after being irradiated with light in the wavelength range of 200nm-400nm for 10 seconds are shown in Table 4. Table 4 Tavg before irradiation (%) 27 After irradiation Tavg (%) 27

In addition, in Embodiment 2, the average transmittances of the first light-blocking portion 221, the second light-blocking portion 222, the third light-blocking portion 223 and the fourth light-blocking portion 224 from the inside to the outside in visible light may be different. In Embodiment 2, the average transmittance of the first light-blocking portion 221 in visible light is Tavg1, the average transmittance of the second light-blocking portion 222 in visible light is Tavg2, the average transmittance of the third light-blocking portion 223 in visible light is Tavg3, and the average transmittance of the fourth light-blocking portion 224 in visible light is Tavg4, wherein Tavg1 > Tavg2 > Tavg3 > Tavg4. In Table 4, the Tavg value is the minimum average transmittance that can be obtained in different light-blocking portions (221-224), which means that the light-blocking portion (at least one of 221-224) has the best light-blocking effect. In other words, in Example 2, Tavg = Tavg4.

<Example 3>

FIG. 5 is a schematic diagram showing a contact lens 300 according to Embodiment 3 of the present invention. In FIG. 5, the contact lens 300 includes an optical zone 310 and a light-blocking annular zone 320. The light-blocking annular zone 320 is disposed around the center point O of the contact lens 300, and the inner periphery 320A of the light-blocking annular zone 320 is circular. The optical zone 310 is the area enclosed by the dotted line. In Embodiment 3, the optical zone 310 and the light-blocking annular zone 320 partially overlap.

The numerical values of parameters such as CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, and BC of Example 3 are recorded in Table 5. Please refer to Example 1 for the definitions of the aforementioned parameters. Table 5 CDmin (mm) 1.50 CDmax/D 0.62 CDmax (mm) 9.00 CDmax-CDmin (mm) 7.50 OD (mm) 8.00 CDmin/OD 0.19 D (mm) 14.50 BC (mm) 8.50 CDmin/D 0.10

The contact lens 300 is made of hydrogel, and the composition of the hydrogel includes the following monomers: hydroxyethyl methacrylate and methacrylic acid. The contact lens 300 is a multifocal contact lens.

The average transmittance of the light-blocking annular region 320 to visible light is Tavg, and the values thereof before and after being irradiated with light in the wavelength range of 200nm-400nm for 10 seconds are shown in Table 6. Table 6 Tavg before irradiation (%) 55 After irradiation Tavg (%) 55

<Example 4>

FIG. 6 is a schematic diagram showing a contact lens 400 according to Embodiment 4 of the present invention. In FIG. 6, the contact lens 400 includes an optical zone 410 and a light-blocking annular zone 420. The light-blocking annular zone 420 is disposed around the center point O of the contact lens 400, and the inner periphery 420A of the light-blocking annular zone 420 is circular. The optical zone 410 is the area enclosed by the dotted line. In Embodiment 4, the optical zone 410 and the light-blocking annular zone 420 partially overlap.

The numerical values of parameters such as CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, and BC of Example 4 are recorded in Table 7. Please refer to Example 1 for the definitions of the aforementioned parameters. Table 7 CDmin (mm) 8.00 CDmax/D 0.68 CDmax (mm) 9.50 CDmax-CDmin (mm) 1.50 OD (mm) 9.00 CDmin/OD 0.89 D (mm) 14.00 BC (mm) 9.00 CDmin/D 0.57

The contact lens 400 is made of hydrogel, and the composition for preparing the hydrogel includes the following monomers: hydroxyethyl methacrylate and 2-methyl-2-acrylate-2,3-dihydroxypropyl ester. The contact lens 400 is a multifocal contact lens, and the contact lens 400 includes a ciliary muscle anesthetic.

The average transmittance of the light-blocking annular region 420 to visible light is Tavg, and the values thereof before and after being irradiated with light in the wavelength range of 200nm-400nm for 10 seconds are shown in Table 8. Table 8 Tavg before irradiation (%) 35 After irradiation Tavg (%) 35

<Example 5>

FIG. 7 is a schematic diagram showing a contact lens 500 according to Embodiment 5 of the present invention. In FIG. 7, the contact lens 500 includes an optical zone 510 and a light-blocking annular zone 520. The light-blocking annular zone 520 is disposed around the center point O of the contact lens 500, and the inner periphery 520A of the light-blocking annular zone 520 is a decagon. The optical zone 510 is the area enclosed by the dotted line. In Embodiment 5, the optical zone 510 and the light-blocking annular zone 520 partially overlap.

The numerical values of parameters such as CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, and BC of Example 5 are recorded in Table 9. Please refer to Example 1 for the definitions of the aforementioned parameters. Table 9 CDmin (mm) 9.00 CDmax/D 0.89 CDmax (mm) 12.50 CDmax-CDmin (mm) 3.50 OD (mm) 10.00 CDmin/OD 0.90 D (mm) 14.00 BC (mm) 9.25 CDmin/D 0.64

The material of the contact lens 500 is hydrogel, and the composition for preparing the hydrogel includes the following monomers: hydroxyethyl methacrylate and N-vinyl-2-pyrrolidone. The contact lens 500 is a single-focus contact lens.

The average transmittance of the light-blocking annular region 520 to visible light is Tavg, and the values thereof before and after being irradiated with light in the wavelength range of 200nm-400nm for 10 seconds are shown in Table 10. Table 10 Tavg before irradiation (%) 15 After irradiation Tavg (%) 15

<Example 6>

FIG. 8 is a schematic diagram showing a contact lens 600 according to Embodiment 6 of the present invention. In FIG. 8 , the contact lens 600 includes an optical zone 610 and a light-blocking annular zone 620. The light-blocking annular zone 620 is disposed around the center point O of the contact lens 600, and the inner periphery 620A of the light-blocking annular zone 620 is a hexagon. The optical zone 610 is the area enclosed by the dotted line. In Embodiment 6, the optical zone 610 partially overlaps with the light-blocking annular zone 620.

The numerical values of parameters such as CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, and BC of Example 6 are recorded in Table 11. Please refer to Example 1 for the definitions of the aforementioned parameters. Table 11 CDmin (mm) 7.50 CDmax/D 0.72 CDmax (mm) 10.50 CDmax-CDmin (mm) 3.00 OD (mm) 11.00 CDmin/OD 0.68 D (mm) 14.50 BC (mm) 9.50 CDmin/D 0.52

The contact lens 600 is made of hydrogel, and the composition for preparing the hydrogel includes the following monomers: hydroxyethyl methacrylate, 2-methyl-2-acrylate-2,3-dihydroxypropyl ester, and N-vinyl-2-pyrrolidone. The contact lens 600 is a single-focus contact lens, and the contact lens 600 includes a ciliary muscle anesthetic.

The light-blocking annular region 620 includes a photochromic material. The photochromic material used in Example 6 is 1′,3′-dihydro-1′,3′,3′-trimethyl-6-nitrospiro[2H-1-benzopyran-2,2′-(2H)-indole]. The average transmittance of the light-blocking annular region 620 in visible light is Tavg, and the values before and after irradiation with light in the wavelength range of 200nm~400nm for 10 seconds are shown in Table 12. Table 12 Tavg before irradiation (%) 40 After irradiation Tavg (%) 10

<Example 7>

FIG. 9 is a schematic diagram of a contact lens 700 according to Embodiment 7 of the present invention. In FIG. 9, the contact lens 700 includes an optical zone 710 and a light-blocking annular zone 720. The light-blocking annular zone 720 is arranged around the center point O of the contact lens 700, and the inner periphery 720A of the light-blocking annular zone 720 is a quadrilateral. Specifically, the light-blocking annular zone 720 includes three light-blocking portions, namely a first light-blocking portion 721, a second light-blocking portion 722, and a third light-blocking portion 723. The optical zone 710 is the area enclosed by the dotted line. In Embodiment 7, the optical zone 710 partially overlaps with the light-blocking annular zone 720.

The numerical values of parameters such as CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, and BC of Example 7 are recorded in Table 13. Please refer to Example 1 for the definitions of the aforementioned parameters. Table 13 CDmin (mm) 4.50 CDmax/D 0.93 CDmax (mm) 14.00 CDmax-CDmin (mm) 9.50 OD (mm) 12.00 CDmin/OD 0.38 D (mm) 15.00 BC (mm) 10.00 CDmin/D 0.30

The material of the contact lens 700 is hydrogel, and the composition of the hydrogel includes the following monomers: hydroxyethyl methacrylate, methacrylic acid, and N-vinyl-2-pyrrolidone. The contact lens 700 is a multifocal contact lens.

The light-blocking annular region 720 includes a photochromic material. The photochromic material used in Example 7 is 1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3′-[3H]naphtho[2,1-b][1,4]oxazine]. The average transmittance of the light-blocking annular region 720 in visible light is Tavg, and the values before and after irradiation with light in the wavelength range of 200nm~400nm for 10 seconds are shown in Table 14. Table 14 Tavg before irradiation (%) 55 After irradiation Tavg (%) 8

In addition, in Embodiment 7, the average transmittance of the first light-blocking portion 721, the second light-blocking portion 722, and the third light-blocking portion 723 from the inside to the outside in visible light may be different. In Embodiment 7, the average transmittance of the first light-blocking portion 721 in visible light is Tavg1, the average transmittance of the second light-blocking portion 722 in visible light is Tavg2, and the average transmittance of the third light-blocking portion 723 in visible light is Tavg3, wherein Tavg1>Tavg2 and Tavg3>Tavg2, Tavg1 may be equal to Tavg3, or may be unequal. In Table 14, the Tavg value is the minimum average transmittance that can be obtained in different light-blocking portions (721-723), which means that the light-blocking portion (at least one of 721-723) has the best light-blocking effect. In other words, in Embodiment 7, Tavg = Tavg2.

<Example 8>

FIG. 10 is a schematic diagram showing a contact lens 800 according to Embodiment 8 of the present invention. In FIG. 10 , the contact lens 800 includes an optical zone 810 and a light-blocking annular zone 820. The light-blocking annular zone 820 is disposed around the center point O of the contact lens 800, and the inner periphery 820A of the light-blocking annular zone 820 is an octagon. Specifically, the light-blocking annular zone 820 includes two light-blocking portions, namely a first light-blocking portion 821 and a second light-blocking portion 822. The optical zone 810 is the area enclosed by the dotted line. In Embodiment 8, the optical zone 810 partially overlaps with the light-blocking annular zone 820.

The numerical values of parameters such as CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, and BC of Example 8 are recorded in Table 15. Please refer to Example 1 for the definitions of the aforementioned parameters. Table 15 CDmin (mm) 5.50 CDmax/D 0.82 CDmax (mm) 11.50 CDmax-CDmin (mm) 6.00 OD (mm) 7.50 CDmin/OD 0.73 D (mm) 14.00 BC (mm) 10.50 CDmin/D 0.39

Contact lens 800 is made of silicone hydrogel, and the composition of silicone hydrogel includes the following monomers: hydroxyethyl methacrylate, N-vinyl-2-pyrrolidone, N,N-dimethylacrylamide, 3-acetoxy-2-hydroxypropoxypropyl terminated polydimethylsiloxane and methyl methacrylate. Contact lens 800 is a multifocal contact lens.

The light-blocking annular region 820 includes a photochromic material, and the photochromic material used in Example 8 is hydroxy-4-methyl-2H-naphtho(1,2-B)pyran-2-one. The average transmittance of the light-blocking annular region 820 in visible light is Tavg, and the values before and after irradiation with light in the wavelength range of 200nm to 400nm for 10 seconds are shown in Table 16. Table 16 Tavg before irradiation (%) 25 After irradiation Tavg (%) 11

In addition, in the eighth embodiment, the average transmittance of the first light-blocking portion 821 and the second light-blocking portion 822 from the inside to the outside in visible light may be different. In the eighth embodiment, the average transmittance of the first light-blocking portion 821 in visible light is Tavg1, and the average transmittance of the second light-blocking portion 822 in visible light is Tavg2, wherein Tavg1 < Tavg2. In Table 16, the value of Tavg is the minimum average transmittance that can be obtained in different light-blocking portions (821-822), which means that the light-blocking portion (at least one of 821-822) has the best light-blocking effect. In other words, in the eighth embodiment, Tavg = Tavg1.

<Example 9>

FIG. 11 is a schematic diagram showing a contact lens 900 according to Embodiment 9 of the present invention. In FIG. 11 , the contact lens 900 includes an optical zone 910 and a light-blocking annular zone 920. The light-blocking annular zone 920 is disposed around the center point O of the contact lens 900, and the inner periphery 920A of the light-blocking annular zone 920 is circular. The optical zone 910 is the area enclosed by the dotted line. In Embodiment 9, the optical zone 910 partially overlaps with the light-blocking annular zone 920.

The numerical values of parameters such as CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, and BC of Example 9 are recorded in Table 17. Please refer to Example 1 for the definitions of the aforementioned parameters. Table 17 CDmin (mm) 3.50 CDmax/D 0.79 CDmax (mm) 11.50 CDmax-CDmin (mm) 8.00 OD (mm) 8.50 CDmin/OD 0.41 D (mm) 14.50 BC (mm) 9.75 CDmin/D 0.24

Contact lens 900 is made of silicone hydrogel, and the composition of silicone hydrogel includes the following monomers: hydroxyethyl methacrylate, methacryloyloxypropyl tris(trimethylsiloxy)silane, (3-methacryloyloxy-2-hydroxypropoxy)propyl bis(trimethylsiloxy)methyl and methyl methacrylate. Contact lens 900 is a single-focus contact lens.

The light-blocking annular region 920 includes a photochromic material, and the photochromic material used in Example 9 is (E)-benzylidene (diphenylmethylene) succinic anhydride. The average transmittance of the light-blocking annular region 920 in visible light is Tavg, and the values before and after irradiation with light in the wavelength range of 200nm-400nm for 10 seconds are shown in Table 18. Table 18 Tavg before irradiation (%) 20 After irradiation Tavg (%) 15

<Example 10>

FIG. 12 is a schematic diagram showing a contact lens 1000 according to Embodiment 10 of the present invention. In FIG. 12, the contact lens 1000 includes an optical zone 1010 and a light-blocking annular zone 1020. The light-blocking annular zone 1020 is disposed around the center point O of the contact lens 1000, and the inner periphery 1020A of the light-blocking annular zone 1020 is circular. The optical zone 1010 is the area enclosed by the dotted line. In Embodiment 10, the optical zone 1010 and the light-blocking annular zone 1020 are staggered.

The numerical values of parameters such as CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, and BC of Example 10 are recorded in Table 19. Please refer to Example 1 for the definitions of the aforementioned parameters. Table 19 CDmin (mm) 6.50 CDmax/D 1.00 CDmax (mm) 13.50 CDmax-CDmin (mm) 7.00 OD (mm) 5.00 CDmin/OD 1.30 D (mm) 13.50 BC (mm) 12.00 CDmin/D 0.48

The material of the contact lens 1000 is silicone hydrogel, and the composition for preparing the silicone hydrogel includes the following monomers: hydroxyethyl methacrylate, N-vinyl-2-pyrrolidone, N,N-dimethylacrylamide, methacryloyloxypropyl tris(trimethylsiloxyalkyl)silane, 3-acetoxy-2-hydroxypropoxypropyl-terminated polydimethylsiloxane, and methyl methacrylate. The contact lens 1000 is a single-focus contact lens, and the contact lens 1000 includes a ciliary muscle anesthetic.

The light-blocking annular region 1020 includes a photochromic material, and the photochromic material used in Example 10 is 9,10-dihydrophenanthrene. The average transmittance of the light-blocking annular region 1020 in visible light is Tavg, and the values before and after irradiation with light in the wavelength range of 200nm-400nm for 10 seconds are shown in Table 20. Table 20 Tavg before irradiation (%) 30 After irradiation Tavg (%) 13

<Example 11>

FIG. 13 is a schematic diagram showing a contact lens 1100 according to Embodiment 11 of the present invention. In FIG. 13 , the contact lens 1100 includes an optical zone 1110 and a light-blocking annular zone 1120. The light-blocking annular zone 1120 is disposed around the center point O of the contact lens 1100, and the inner periphery 1120A of the light-blocking annular zone 1120 is circular. The optical zone 1110 is the area enclosed by the dotted line. In Embodiment 11, the optical zone 1110 and the light-blocking annular zone 1120 are staggered.

The numerical values of parameters such as CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, and BC of Example 11 are recorded in Table 21. Please refer to Example 1 for the definitions of the aforementioned parameters. Table 21 CDmin (mm) 8.50 CDmax/D 0.89 CDmax (mm) 12.50 CDmax-CDmin (mm) 4.00 OD (mm) 7.00 CDmin/OD 1.21 D (mm) 14.00 BC (mm) 11.00 CDmin/D 0.61

The material of the contact lens 1100 is silicone hydrogel, and the composition of the silicone hydrogel includes the following monomers: hydroxyethyl methacrylate, N,N-dimethylacrylamide, and (3-methacryloyloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methyl. The contact lens 1100 is a multifocal contact lens, and the contact lens 1100 includes a ciliary muscle anesthetic.

The light-blocking annular region 1120 includes a photochromic material. The photochromic material used in Example 11 includes 1,3-dihydro-1,3,3-trimethylspiro[2H-indole-2,3′-[3H]naphtho[2,1-b][1,4]oxazine] and (E)-benzylidene(diphenylmethylene)succinic anhydride. The average transmittance of the light-blocking annular region 1120 in visible light is Tavg, and the values before and after irradiation with light in the wavelength range of 200nm~400nm for 10 seconds are shown in Table 22. Table 22 Tavg before irradiation (%) 90 After irradiation Tavg (%) 5

<Example 12>

FIG. 14 is a schematic diagram of a contact lens 1200 according to Embodiment 12 of the present invention. In FIG. 14, the contact lens 1200 includes an optical zone 1210 and a light-blocking annular zone 1220. The light-blocking annular zone 1220 is disposed around the center point O of the contact lens 1200, and the inner periphery 1220A of the light-blocking annular zone 1220 is circular. The optical zone 1210 is the area enclosed by the dotted line. In Embodiment 12, the optical zone 1210 partially overlaps with the light-blocking annular zone 1220.

The numerical values of parameters such as CDmin, CDmax, OD, D, CDmin/D, CDmax/D, CDmax-CDmin, CDmin/OD, and BC of Example 12 are recorded in Table 23. Please refer to Example 1 for the definitions of the aforementioned parameters. Table 23 CDmin (mm) 2.00 CDmax/D 0.97 CDmax (mm) 14.00 CDmax-CDmin (mm) 12.00 OD (mm) 3.50 CDmin/OD 0.57 D (mm) 14.50 BC (mm) 13.50 CDmin/D 0.14

The material of the contact lens 1200 is silicone hydrogel, and the composition of the silicone hydrogel includes the following monomers: hydroxyethyl methacrylate, 2-methyl-2-acrylate-2,3-dihydroxypropyl ester, N-vinyl-2-pyrrolidone, N,N-dimethylacrylamide, methacryloxypropyl tris(trimethylsiloxyalkyl)silane, (3-methacryloxy-2-hydroxypropoxy)propyl bis(trimethylsiloxy)methyl, 3-acetoxy-2-hydroxypropoxypropyl terminated polydimethylsiloxane, and methyl methacrylate. The contact lens 1200 is a multifocal contact lens.

The light-blocking annular region 1220 includes a photochromic material. The photochromic material used in Example 12 includes 1′,3′-dihydro-1′,3′,3′-trimethyl-6-nitrospiro[2H-1-benzopyran-2,2′-(2H)-indole], hydroxy-4-methyl-2H-naphtho(1,2-B)pyran-2-one, and 9,10-dihydrophenanthrene. The average transmittance of the light-blocking annular region 1220 in visible light is Tavg, and the values before and after irradiation with light in the wavelength range of 200nm~400nm for 10 seconds are shown in Table 24. Table 24 Tavg before irradiation (%) 45 After irradiation Tavg (%) 3

<Example 13>

FIG. 15 is a schematic diagram showing a contact lens 1300 according to Embodiment 13 of the present invention. In FIG. 15 , the contact lens 1300 includes an optical zone 1310 and a light-blocking annular zone 1320. The light-blocking annular zone 1320 is disposed around the center point O of the contact lens 1300, and the inner periphery 1320A of the light-blocking annular zone 1320 is circular. The optical zone 1310 is the area enclosed by the dotted line. In Embodiment 13, the optical zone 1310 and the light-blocking annular zone 1320 are staggered. In embodiment 13, the light-blocking annular area 1320 includes only one light-blocking portion (not separately labeled), and the light-blocking portion includes a plurality of micro light-blocking portions 1320a, and these micro light-blocking portions 1320a are arranged in a radial shape, and the average transmittance of these micro light-blocking portions 1320a in visible light can be gradually changed, that is, different micro light-blocking portions 1320a can have different color depth changes along the clockwise direction or the counterclockwise direction. In embodiment 13, the color depth changes from the 12 o'clock position along the clockwise direction are shallow gradual, deep gradual, shallow gradual, and deep gradual again. In other embodiments, other color depth changes can be arranged according to actual needs.

According to the contact lens of the present invention, the optical zone refers to the range covered by the base curve of the contact lens, that is, the area with refractive power.

According to the contact lens of the present invention, the parameter design is not limited to be used only on the front surface or the back surface of the contact lens, and can be designed on either surface or both the front and back surfaces.

According to the contact lens of the present invention, the light-blocking annular region can be formed on the contact lens by transferring, printing or coating the light-blocking material, or the light-blocking material can be mixed into the composition for preparing the light-blocking annular region so that the light-blocking material is dispersed in the entire light-blocking annular region. In addition, the light-blocking contact lens can be manufactured by selecting and adjusting the concentration and color of the light-blocking material. The light-blocking material can be manufactured to have different degrees of light transmittance according to different needs to effectively reduce the average transmittance of visible light. The light-blocking material can be a color material approved for medical devices by the Taiwan Food and Drug Administration (TFDA), the U.S. Food and Drug Administration (FDA) or any national food and drug administration.

According to the contact lenses of the present invention, the photovariable material can be transformed into a color with low visible light transmittance by absorbing light (such as blue light, UV, etc.), effectively reducing or even blocking visible light transmission. When the light source disappears, the photovariable material can be restored to its original visible light transmittance, and the transformation is a reversible reaction.

According to the contact lens of the present invention, the ciliary muscle paralytic agent includes but is not limited to atropine ((3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate), tropicamide (N-ethyl-3-hydroxy-2-phenyl-N- (4-pyridinylmethyl)propanamide), cyclopentolate (2-(dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate), homatropine ((3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate), scopolamine ((1R,2R,4S,5S,7s)-9-methyl-3-oxa-9- azatricyclo[3.3.1.0 ^2,4 ]non-7-yl(2S)-3-hydroxy-2-phenylpropanoate) and eucatropine (1,2,2,6-tetramethyl-4-piperidinyl hydroxyl (phenyl)acetate) and their salts. Ciliary muscle anesthetics are also called mydriatics and belong to the class of parasympathetic nerve blockers, that is, they are non-selective M-type muscarinic receptor blockers that can paralyze and relax the ciliary muscles that control the pupil by blocking muscarinic receptors, thereby dilating the pupil.

Although the present invention has been disclosed in the above embodiments, it is not intended to limit the present invention. Anyone skilled in the art can make various changes and modifications without departing from the spirit and scope of the present invention. Therefore, the scope of protection of the present invention shall be determined by the scope of the attached patent application.

10,100,200,300,400,500,600,700,800,900,1000,1100,1200,1300: Contact lenses 11,110,210,310,410,510,610,710,810,910,1010,1110,1210,1310: Optical area 12,120,220,320,4 20,520,620,720,820,920,1020,1120,1220,1320: light-blocking annular area 221,721,821: first light-blocking part 222,722,822: second light-blocking part 223,723: third light-blocking part 224: fourth light-blocking part 1320a: micro light-blocking part 12A,120A,220A,320A,420A ,520A,620A,720A,820A,920A,1020A,1120A,1220A,1320A: Inner periphery O: Center point 20: Wetting solution 30: Contact lens product CDmin: Minimum diameter of light blocking ring area CDmax: Maximum diameter of light blocking ring area OD: Maximum diameter of optical zone D: Maximum diameter of contact lens BC: Contact lens Base curve Tavg: Average transmittance of the light-blocking annular area in visible light Tavg1: Average transmittance of the first light-blocking part in visible light Tavg2: Average transmittance of the second light-blocking part in visible light Tavg3: Average transmittance of the third light-blocking part in visible light Tavg4: Average transmittance of the fourth light-blocking part in visible light ConA: Weight percentage concentration of ciliary muscle paralytic in contact lenses or in the immersion solution

Figure 1A is a schematic diagram showing a contact lens according to one embodiment of the present invention; Figure 1B is a schematic diagram showing a side view of the contact lens in Figure 1A; Figure 2 is a schematic diagram showing a contact lens product according to another embodiment of the present invention; Figure 3 is a schematic diagram showing a contact lens according to embodiment 1 of the present invention; Figure 4 is a schematic diagram showing a contact lens according to embodiment 2 of the present invention; Figure 5 is a schematic diagram showing a contact lens according to embodiment 3 of the present invention; Figure 6 is a schematic diagram showing a contact lens according to embodiment 4 of the present invention; Figure 7 is a schematic diagram showing a contact lens according to embodiment 5 of the present invention; Figure 8 is FIG. 9 is a schematic diagram of a contact lens according to Embodiment 7 of the present invention; FIG. 10 is a schematic diagram of a contact lens according to Embodiment 8 of the present invention; FIG. 11 is a schematic diagram of a contact lens according to Embodiment 9 of the present invention; FIG. 12 is a schematic diagram of a contact lens according to Embodiment 10 of the present invention; FIG. 13 is a schematic diagram of a contact lens according to Embodiment 11 of the present invention; FIG. 14 is a schematic diagram of a contact lens according to Embodiment 12 of the present invention; and FIG. 15 is a schematic diagram of a contact lens according to Embodiment 13 of the present invention.

10: Contact lenses

11: Optical area

12: Light-blocking annular area

12A: Inner periphery

O: Center point

D: Maximum diameter of contact lenses

OD: Maximum diameter of the optical zone

CDmin: minimum diameter of the light-blocking annular area

CDmax: Maximum diameter of the light-blocking annular area

Claims (15)

A contact lens comprises: an optical zone; and at least one light-blocking annular zone, which is arranged around the center point of the contact lens, wherein the light-blocking annular zone comprises at least two light-blocking portions, the two light-blocking portions are respectively a first light-blocking portion and a second light-blocking portion from the inside to the outside, and there is a gap between the first light-blocking portion and the second light-blocking portion; wherein the minimum diameter of the light-blocking annular zone is CDmin, and the maximum diameter of the optical zone is OD, which meets the following conditions: 0.15

CDmin/OD

1.40. The contact lens as described in claim 1, wherein the average transmittance of the at least two light-blocking portions to visible light changes gradually. The contact lens as described in claim 2, wherein the average transmittance of the first light-blocking portion in visible light is Tavg1, and the average transmittance of the second light-blocking portion in visible light is Tavg2, which satisfies the following condition: Tavg1<Tavg2. The contact lens as described in claim 2, wherein the average transmittance of the first light-blocking portion in visible light is Tavg1, and the average transmittance of the second light-blocking portion in visible light is Tavg2, which satisfies the following condition: Tavg1>Tavg2. The contact lens as described in claim 2, wherein the light-blocking annular area includes at least three light-blocking portions, and the at least three light-blocking portions are respectively the first light-blocking portion, the second light-blocking portion, and a third light-blocking portion from the inside to the outside. The contact lens as described in claim 5, wherein the average transmittance of the first light-blocking portion in visible light is Tavg1, the average transmittance of the second light-blocking portion in visible light is Tavg2, and the average transmittance of the third light-blocking portion in visible light is Tavg3, which satisfies the following conditions: Tavg1<Tavg2; and Tavg3<Tavg2. The contact lens as described in claim 5, wherein the average transmittance of the first light-blocking portion in visible light is Tavg1, the average transmittance of the second light-blocking portion in visible light is Tavg2, and the average transmittance of the third light-blocking portion in visible light is Tavg3, which satisfies the following conditions: Tavg1>Tavg2; and Tavg3>Tavg2. The contact lens as described in claim 5, wherein the light-blocking annular area includes at least four light-blocking portions, the at least four light-blocking portions are respectively the first light-blocking portion, the second light-blocking portion, the third light-blocking portion and a fourth light-blocking portion from the inside to the outside, and the inner periphery of the light-blocking annular area is circular. The contact lens as described in claim 8, wherein the average transmittance of the first light-blocking portion in visible light is Tavg1, the average transmittance of the second light-blocking portion in visible light is Tavg2, the average transmittance of the third light-blocking portion in visible light is Tavg3, and the average transmittance of the fourth light-blocking portion in visible light is Tavg4, which satisfies the following conditions: Tavg1>Tavg2>Tavg3>Tavg4. The contact lens as described in claim 1, wherein the optical area and the light-blocking ring-shaped area partially overlap. The contact lens as described in claim 1, wherein the light-blocking annular area further comprises a plurality of micro-light-blocking portions, and the micro-light-blocking portions are arranged in a radial shape. The contact lens as described in claim 1, wherein the contact lens comprises a photochromic material, and the photochromic material is a spiropyran compound. The contact lens as claimed in claim 1, wherein the minimum diameter of the light-blocking ring-shaped area is CDmin, the maximum diameter of the contact lens is D, the maximum diameter of the optical zone is OD, the maximum diameter of the light-blocking ring-shaped area is CDmax, and the following conditions are met: 0.30

CDmin/D

0.43; 0.38

CDmin/OD

0.80; and 6.00mm

CDmax-CDmin

9.5mm. The contact lens as claimed in claim 1, wherein the average transmittance of the light-blocking annular region in visible light is Tavg, which satisfies the following conditions: 0%<Tavg

55%. A contact lens product, comprising: a contact lens as described in claim 1; and an immersion solution, in which the contact lens is immersed; wherein at least one of the contact lens and the immersion solution contains a ciliary muscle anesthetic.

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