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TWI617428B - Droplet generating device and method - Google Patents

Droplet generating device and method Download PDF

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Publication number
TWI617428B
TWI617428B TW105138720A TW105138720A TWI617428B TW I617428 B TWI617428 B TW I617428B TW 105138720 A TW105138720 A TW 105138720A TW 105138720 A TW105138720 A TW 105138720A TW I617428 B TWI617428 B TW I617428B
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Taiwan
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fluid
bearing
unit
rotating disk
droplet
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TW105138720A
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Chinese (zh)
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TW201819158A (en
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李承儒
洪敏偉
黃國政
莊文寧
歐耿良
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財團法人國家實驗研究院
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Publication of TW201819158A publication Critical patent/TW201819158A/en

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Abstract

一種液滴生成裝置,包含:一流體阻斷單元,包括一流體阻斷旋轉盤,該流體阻斷旋轉盤具有一第一軸承,隨著該流體阻斷旋轉盤旋轉,該第一軸承阻斷一管線中之一流體以產生體積固定之一部分流體;以及一液滴產生單元,包括一拍擊外推旋轉盤,該拍擊外推旋轉盤具有一第二軸承,隨著該拍擊外推旋轉盤旋轉,該第二軸承拍擊並外推該管線以從該部分流體生成一液滴。 A droplet generating device comprising: a fluid blocking unit comprising a fluid blocking rotating disk, the fluid blocking rotating disk having a first bearing, the first bearing blocking as the fluid blocks rotation of the rotating disk a fluid in a line to generate a volume of a portion of the fluid; and a droplet generating unit comprising a slap extrapolation rotating disk, the slamming extrapolating rotating disk having a second bearing, extrapolated with the slap The rotating disk rotates and the second bearing slaps and extrapolates the line to create a droplet from the portion of the fluid.

Description

液滴生成裝置及方法 Droplet generating device and method

本發明係關於一種液滴生成裝置及方法,尤指一種適用於包含生物因子之溶液的液滴生成裝置及方法。 The present invention relates to a droplet generating apparatus and method, and more particularly to a droplet generating apparatus and method suitable for use in a solution containing a biological factor.

3D列印,又稱積層製造,美國材料試驗協會將積層製造的成型技術分類為七種:一、材料擠製成型(Material Extrusion)、二、疊層製造成型(Sheet Lamination)三、材料噴塗成型(Material Jetting)、四、光聚合固化技術(Vat PhotoPolymerization)、五、黏著劑噴膠成型(Binder Jetting)、六、粉體熔化成型技術(Powder Bed Fusion,PBF)以及七、指向性能量沉積技術(Directed Energy Deposition,DED)等。 3D printing, also known as laminated manufacturing, the American Society for Testing and Materials classifies the forming technology of laminated manufacturing into seven types: First, Material Extrusion, Second, Sheet Lamination, Material Spraying Material Jetting, V. Photopolymerization (Vat PhotoPolymerization), V. Binder Jetting, Powder Bed Fusion (PBF) and 7. Directional Energy Deposition Directed Energy Deposition (DED), etc.

近年來3D列印技術快速發展,其應用領域包含工業設計、產品驗證、醫療與航空太空等產業。其中於醫療產業之應用,例如醫療器材與人工骨材之製作,常使用黏著劑噴膠成型技術,其主要概念為以粉體材料均勻且緊實地鋪平於工作平面上,透過成型用溶液噴灑於粉末欲成型區進行粉體材料黏合,並且逐層堆疊以獲得成品。成型用溶液若包含生物分子,則能夠直接或間接的促進細胞的增殖與分化,因而有助於患者的恢復。 In recent years, 3D printing technology has developed rapidly, and its application fields include industrial design, product verification, medical and aerospace industries. Among them, in the application of the medical industry, such as the production of medical equipment and artificial bone materials, the adhesive spray molding technology is often used. The main concept is to uniformly and tightly lay the powder material on the working plane and spray through the molding solution. The powder material is adhered to the powder forming zone and stacked layer by layer to obtain a finished product. If the molding solution contains biomolecules, it can directly or indirectly promote cell proliferation and differentiation, and thus contribute to the recovery of the patient.

然而,市售的3D列印系統之成型用溶液皆不含生物分子,因此可以壓電方式快速驅動噴出尺寸微小之液滴進行成型。但是包含生物因子之溶液內分子尺寸較大,溶液黏稠度亦相對較高,因此無法以壓電方 式驅動噴出微小液滴,進而影響成型後之模型尺寸與精度。其他液滴生成方式包括了氣壓式例如點膠機。點膠機使用撞針對噴嘴瞬間加壓以產生液滴,由於撞針直接接觸液材,撞擊越多次液材溫度越高,因此會影響包含生物因子之成型用溶液的生物活性。 However, the molding solutions for the commercially available 3D printing system do not contain biomolecules, so that it is possible to rapidly drive the droplets of small size to be molded by piezoelectric means. However, the molecular size of the solution containing the biological factor is large, and the viscosity of the solution is relatively high, so the piezoelectric side cannot be used. The drive drives tiny droplets, which in turn affects the size and accuracy of the model after molding. Other droplet formation methods include pneumatics such as dispensers. The dispenser uses a collision to instantaneously pressurize the nozzle to generate droplets. Since the striker directly contacts the liquid material, the more the impact, the higher the temperature of the liquid material, and thus the biological activity of the molding solution containing the biological factor.

因此,提供一種適用於包含生物因子溶液的液滴生成裝置及方法有其必要性。 Therefore, it is necessary to provide a droplet generating apparatus and method suitable for containing a biological factor solution.

本發明之第一面向係提供一種液滴生成裝置,包含:一流體阻斷單元,包括一流體阻斷旋轉盤,該流體阻斷旋轉盤具有一第一軸承,隨著該流體阻斷旋轉盤旋轉,該第一軸承阻斷一管線中之一流體以產生體積固定之一部分流體;以及一液滴產生單元,包括一拍擊外推旋轉盤,該拍擊外推旋轉盤具有一第二軸承,隨著該拍擊外推旋轉盤旋轉,該第二軸承拍擊並外推該管線以從該部分流體生成一液滴。 The first aspect of the present invention provides a droplet generating apparatus comprising: a fluid blocking unit including a fluid blocking rotating disk having a first bearing, the rotating disk being blocked with the fluid Rotating, the first bearing blocks one of the fluids in a line to produce a volume of a portion of the fluid; and a droplet generating unit includes a slamming extrapolated rotating disk having a second bearing As the slap pushes the rotary disk to rotate, the second bearing slaps and extrapolates the line to generate a droplet from the portion of the fluid.

本發明之第二面向係提供一種液滴生成方法,包含下列步驟:提供一流體阻斷單元,該流體阻斷單元包括具有一第一軸承之一流體阻斷旋轉盤;隨著該流體阻斷旋轉盤旋轉,該第一軸承阻斷一管線中之一流體以產生體積固定之一部分流體;提供一液滴產生單元,該液滴產生單元包括具有一第二軸承之一拍擊外推旋轉盤;以及隨著該拍擊外推旋轉盤旋轉,該第二軸承拍擊並外推該管線以從該部分流體生成一液滴。 A second aspect of the present invention provides a method of droplet formation comprising the steps of: providing a fluid blocking unit comprising a fluid blocking rotating disk having a first bearing; with the fluid blocking Rotating the disk, the first bearing blocks one of the fluids in a line to produce a volume of a portion of the fluid; providing a droplet generating unit, the droplet generating unit including one of the second bearings And as the slap extrapolates the rotating disk to rotate, the second bearing slaps and extrapolates the line to generate a droplet from the portion of the fluid.

本發明之第三面向係提供一種液滴生成裝置,用以控制供應一流體之一管線之液滴供應,其中該管線具一流入端及一流出端,該液滴生成裝置包含:一流體阻斷單元,用以阻斷該流體自該流入端額外供應該 管線;以及一液滴產生單元,以一預定壓力在該流體阻斷單元及該流出端間擠壓該管線,以從該流出端生成一液滴。 The third aspect of the present invention provides a droplet generating device for controlling supply of a droplet of a line supplying a fluid, wherein the line has an inflow end and a first-class outlet, the droplet generating device comprising: a fluid resistance a breaking unit for blocking the supply of the fluid from the inflow end a line; and a droplet generating unit that presses the line between the fluid blocking unit and the outflow end at a predetermined pressure to generate a droplet from the outflow end.

本發明之第四面向係提供一種液滴生成裝置,用以控制供應一流體之一管線之液滴供應,其中該管線具一流入端及一流出端,該液滴生成裝置包含:一流體供應切斷單元,用以切斷該流體之供應該管線;以及一液滴產生單元,以一預定壓力在該流體供應切斷單元及該流出端間擠壓該管線,以從該流出端生成一液滴。 The fourth aspect of the present invention provides a droplet generating device for controlling supply of a droplet of a line supplying a fluid, wherein the line has an inflow end and a first-class outlet, the droplet generating device comprising: a fluid supply a cutting unit for cutting off the supply of the fluid; and a droplet generating unit for squeezing the line between the fluid supply shut-off unit and the outflow end at a predetermined pressure to generate a flow from the outflow end Droplet.

10、20、30‧‧‧液滴生成裝置 10, 20, 30‧‧‧ droplet generating device

11、21‧‧‧流體阻斷單元 11, 21‧‧‧ fluid blocking unit

111、211‧‧‧流體阻斷旋轉盤 111, 211‧‧‧ fluid blocking rotating disk

112、212‧‧‧第一軸承 112, 212‧‧‧ first bearing

113‧‧‧第一上部 113‧‧‧ first upper part

114‧‧‧第一下部 114‧‧‧First lower part

115‧‧‧第一孔洞對 115‧‧‧ first hole pair

116‧‧‧第一馬達 116‧‧‧First motor

117‧‧‧第一中心部分 117‧‧‧ first central part

118‧‧‧第一傳動軸 118‧‧‧First drive shaft

12、22、32‧‧‧液滴產生單元 12, 22, 32‧‧‧ droplet generating unit

121、221‧‧‧拍擊外推旋轉盤 121, 221‧‧ ‧ slap push-out rotary disk

122、222‧‧‧第二軸承 122, 222‧‧‧ second bearing

123‧‧‧第二上部 123‧‧‧Second upper

124‧‧‧第二下部 124‧‧‧second lower part

125‧‧‧第二孔洞對 125‧‧‧Second hole pair

126‧‧‧第二馬達 126‧‧‧second motor

127‧‧‧第二中心部分 127‧‧‧ Second central part

128‧‧‧第二傳動軸 128‧‧‧Second drive shaft

13、23、33‧‧‧管線 13, 23, 33‧ ‧ pipeline

131、231、331‧‧‧流體 131, 231, 331‧‧‧ fluid

132、232‧‧‧部分流體 132, 232‧‧‧ part of the fluid

133‧‧‧針頭 133‧‧‧ needle

134、234、334‧‧‧液滴 134, 234, 334‧‧‧ droplets

14‧‧‧定量供料單元 14‧‧‧Quantitative Feeding Unit

141‧‧‧蠕動幫浦 141‧‧‧ creeping pump

142‧‧‧驅動馬達 142‧‧‧Drive motor

15‧‧‧時序控制單元 15‧‧‧Sequence Control Unit

16‧‧‧基座 16‧‧‧Base

161‧‧‧固定元件 161‧‧‧Fixed components

162‧‧‧溝槽 162‧‧‧ trench

31‧‧‧流體供應切斷單元 31‧‧‧Fluid supply cut-off unit

A、C‧‧‧流入端 A, C‧‧‧ inflow

B、D‧‧‧流出端 B, D‧‧‧ outflow

第一圖顯示本發明第一實施例之液滴生成裝置。 The first figure shows a droplet generating device of a first embodiment of the present invention.

第二圖(a)顯示本發明第一實施例之流體阻斷旋轉盤。 The second diagram (a) shows the fluid blocking rotary disk of the first embodiment of the present invention.

第二圖(b)顯示本發明第一實施例之拍擊外推旋轉盤。 The second figure (b) shows the slap extrapolation rotary disk of the first embodiment of the present invention.

第二圖(c)顯示本發明第一實施例之流體阻斷旋轉盤及拍擊外推旋轉盤。 The second figure (c) shows the fluid blocking rotary disk and the slamming extrapolation rotary disk of the first embodiment of the present invention.

第三圖(a)顯示本發明第一實施例之第一軸承。 The third figure (a) shows the first bearing of the first embodiment of the present invention.

第三圖(b)顯示本發明第一實施例之流體阻斷旋轉盤及第一軸承。 The third figure (b) shows the fluid blocking rotary disk and the first bearing of the first embodiment of the present invention.

第四圖顯示本發明第二實施例之液滴生成裝置。 The fourth figure shows the droplet generating device of the second embodiment of the present invention.

第五圖顯示本發明第三實施例之液滴生成裝置。 Fig. 5 is a view showing a droplet generating device of a third embodiment of the present invention.

有關本發明之技術內容、特點及功效,藉由以下較佳實施例的詳細說明將可清楚的呈現。 The details of the present invention will be apparent from the following detailed description of the preferred embodiments.

請參閱第一圖至第三圖(b),本發明第一實施例係提供一種 液滴生成裝置10,該液滴生成裝置10包含一流體阻斷單元11,該流體阻斷單元11包括一流體阻斷旋轉盤111,該流體阻斷旋轉盤111具有一第一軸承112,隨著該流體阻斷旋轉盤111旋轉,該第一軸承112阻斷一管線13中之一流體131以產生體積固定之一部分流體132,其中該流體阻斷旋轉盤111可具有一第一上部113及一第一下部114,該第一軸承112可藉由螺絲或其他固定元件固定於該第一上部113及該第一下部114之間,固定的方法為使該第一軸承112固定於該流體阻斷旋轉盤111上的定點,且能以其中心為軸進行旋轉,如此該第一軸承111是以滾動的方式阻斷該管線13中之該流體131,因此能夠減少該第一軸承111的磨損。該流體阻斷旋轉盤111具有一或多對第一孔洞對115供固定該第一軸承111,該第一孔洞對115分別位於該第一上部113及該第一下部114,該第一孔洞對115的位置以能使該第一軸承112壓抵該管線13以至阻斷該管線13中之該流體131為準。 Referring to the first to third figures (b), the first embodiment of the present invention provides a a droplet generating device 10, the droplet generating device 10 includes a fluid blocking unit 11 including a fluid blocking rotating disk 111 having a first bearing 112, The fluid blocking rotary disk 111 rotates, the first bearing 112 blocks one of the fluids 131 in a line 13 to produce a volume-fixed portion of the fluid 132, wherein the fluid-blocking rotating disk 111 can have a first upper portion 113 and a first lower portion 114, the first bearing 112 can be fixed between the first upper portion 113 and the first lower portion 114 by screws or other fixing elements, and the fixing method is to fix the first bearing 112 to the first bearing 112. The fluid blocks a fixed point on the rotary disk 111 and is rotatable about its center, such that the first bearing 111 blocks the fluid 131 in the line 13 in a rolling manner, thereby reducing the first bearing 111. Wear and tear. The fluid blocking rotary disk 111 has one or more pairs of first hole pairs 115 for fixing the first bearing 111. The first hole pair 115 is located at the first upper portion 113 and the first lower portion 114, respectively. The position of the pair 115 is such that the first bearing 112 is pressed against the line 13 to block the fluid 131 in the line 13.

該液滴生成裝置10亦包含一液滴產生單元12,該液滴產生單元12包括一拍擊外推旋轉盤121,該拍擊外推旋轉盤121具有一第二軸承122,隨著該拍擊外推旋轉盤121旋轉,該第二軸承122拍擊並外推該管線13以從該部分流體132生成一液滴134,該液滴134可經由一針頭133生成,但不限於此。該拍擊外推旋轉盤121可具有一第二上部123及一第二下部124,該第二軸承122可藉由螺絲或其他固定元件固定於該第二上部123及該第二下部124之間,固定的方法為使該第二軸承122固定於該拍擊外推旋轉盤121上的定點,且能以其中心為軸進行旋轉,如此該第二軸承122是以滾動的方式拍擊並外推該管線13,因此能夠減少該第二軸承122的磨損。該拍擊外推旋轉盤121具有一或多對第二孔洞對125供固定該第二軸承122,該第二孔洞 對125的位置以能使該第二軸承122拍擊並外推該管線13但不至阻斷該管線中之該流體131為準。該第一軸承112與該第二軸承122兩者可以相同,亦可不同。該第一軸承112固定於該流體阻斷旋轉盤111的方式原則上與該第二軸承122固定於該拍擊外推旋轉盤121的方式相同。 The droplet generating device 10 also includes a droplet generating unit 12, the droplet generating unit 12 includes a tapping extrapolation rotating disc 121 having a second bearing 122 along with the beat The outer rotary disk 121 is rotated, and the second bearing 122 slaps and extrapolates the line 13 to generate a droplet 134 from the portion of the fluid 132. The droplet 134 can be generated via a needle 133, but is not limited thereto. The slap-out rotary disk 121 can have a second upper portion 123 and a second lower portion 124. The second bearing 122 can be fixed between the second upper portion 123 and the second lower portion 124 by screws or other fixing elements. The fixing method is to fix the second bearing 122 to the fixed point on the slap pushing rotary disk 121, and can rotate with the center thereof as an axis, so that the second bearing 122 is slammed in a rolling manner. This line 13 is pushed, so that the wear of the second bearing 122 can be reduced. The tapping extrapolation rotating disc 121 has one or more pairs of second hole pairs 125 for fixing the second bearing 122, the second hole The position of the pair 125 is such that the second bearing 122 can be tapped and the line 13 is extrapolated but the fluid 131 in the line is not blocked. The first bearing 112 and the second bearing 122 may be the same or different. The manner in which the first bearing 112 is fixed to the fluid blocking rotary disk 111 is in principle the same as the manner in which the second bearing 122 is fixed to the slamming extrapolation rotary disk 121.

阻斷該管線13中之該流體131以產生體積固定之該部分流體132可避免在該第二軸承122拍擊並外推該管線13以從該部分流體132生成該液滴134時該流體回流,因此可避免該流體132回流而導致生成該液滴134時力道大幅減弱。另一方面,拍擊並外推的動作可使該部分流體132之表面張力承受不住重量而提前形成液滴134,因此可得到體積較小的液滴。使用該液滴生成裝置10不需過快的速度即可得到體積較小的液滴,因此亦可避免過快的速度導致在進行3D列印之黏著劑噴膠成型技術時液滴大力撞擊粉末而造成粉末飛散。 Blocking the fluid 131 in the line 13 to create a volumetric portion of the fluid 132 prevents the fluid from flowing back when the second bearing 122 slaps and extrapolates the line 13 to generate the droplet 134 from the portion of the fluid 132. Therefore, it is possible to prevent the fluid 132 from flowing back and causing a significant weakening of the force when the droplet 134 is formed. On the other hand, the action of slap and extrapolation can cause the surface tension of the portion of the fluid 132 to withstand the weight and form the droplet 134 in advance, so that a droplet having a small volume can be obtained. The droplet generating device 10 can be used to obtain a droplet having a small volume without excessively fast speed, and thus can avoid excessively fast speeds, and the droplets strongly collide with the powder during the 3D printing of the adhesive dispensing technique. And the powder is scattered.

該第一軸承112與該流體阻斷旋轉盤111之一邊緣的距離可較該第二軸承122與該拍擊外推旋轉盤121之一邊緣的距離為近,差距可為0.5-1mm,但不限於此。 The distance between the first bearing 112 and one edge of the fluid blocking rotating disk 111 may be closer than the edge of the second bearing 122 to the edge of the slamming rotary disk 121, and the difference may be 0.5-1 mm, but the difference may be 0.5-1 mm, but Not limited to this.

在製造本發明之該流體阻斷旋轉盤111及該拍擊外推旋轉盤121時,可製造同時具有該第一孔洞對115及該第二孔洞對125的一旋轉盤,再視需要選擇該第一孔洞對115或該第二孔洞對125固定該第一軸承112或該第二軸承122,如此只需製造一種規格的旋轉盤即可得到該流體阻斷旋轉盤111及該拍擊外推旋轉盤121。 When manufacturing the fluid blocking rotating disk 111 of the present invention and the slamming external rotating disk 121, a rotating disk having the first hole pair 115 and the second hole pair 125 can be manufactured, and then selected as needed. The first hole pair 115 or the second hole pair 125 fixes the first bearing 112 or the second bearing 122, so that only one type of rotating disk can be manufactured to obtain the fluid blocking rotating disk 111 and the slamming extrapolation Rotating disk 121.

該流體阻斷單元11可更包括一第一馬達116,該液滴產生單元12可更包括一第二馬達126,其中該流體阻斷旋轉盤111之一第一中心部 分117與該第一馬達116的一第一傳動軸118相接而可受該第一馬達116帶動旋轉,隨著該流體阻斷旋轉盤111旋轉,該第一軸承112阻斷該管線13中之該流體131以產生體積固定之該部分流體132。該拍擊外推旋轉盤121之一第二中心部分127與該第二馬達126的一第二傳動軸128相接而可受該第二馬達126帶動旋轉,隨著該拍擊外推旋轉盤121旋轉,該第二軸承122拍擊並外推該管線13以從該部分流體132生成該液滴134。該液滴生成裝置10運作時可以阻斷一次,拍擊外推一次;亦可阻斷一次,拍擊外推多次。 The fluid blocking unit 11 may further include a first motor 116, and the liquid droplet generating unit 12 may further include a second motor 126, wherein the fluid blocks one of the first central portions of the rotating disk 111. The minute portion 117 is in contact with a first transmission shaft 118 of the first motor 116 and is rotatable by the first motor 116. The first bearing 112 blocks the pipeline 13 as the fluid blocks the rotation of the rotary disk 111. The fluid 131 is created to produce a portion of the fluid 132 that is fixed in volume. The second central portion 127 of the slap-out rotary disk 121 is coupled to a second transmission shaft 128 of the second motor 126 to be rotated by the second motor 126, and the rotary disk is extrapolated with the slap 121 rotates, the second bearing 122 slaps and extrapolates the line 13 to generate the droplet 134 from the portion of the fluid 132. When the droplet generating device 10 is in operation, it can be blocked once, and the slap can be extrapolated once; it can also be blocked once, and the slap is extrapolated multiple times.

該液滴生成裝置10可更包含一定量供料單元14及一時序控制單元15,其中該定量供料單元14可包括一蠕動幫浦141及一驅動馬達142。該驅動馬達142連接於該蠕動幫浦141,用以驅動該蠕動幫浦141提供一壓力,以使該流體131於該管線13內流動,但該定量供料單元14可採用的手段並不限於此,凡是能夠達到定量供料之目的均可。該時序控制單元15分別與該定量供料單元14、該流體阻斷單元11及該液滴產生單元12連接,並藉由控制該定量供料單元14、該流體阻斷單元11及該液滴產生單元12的各別驅動時間來控制該液滴134之尺寸、形狀及噴射速度,例如控制供料速度的調配及旋轉盤介入的時間,速度較快則液滴較小,突然截斷則液滴會牽絲,牽絲的液滴在進行3D列印之黏著劑噴膠成型技術時撞擊力小,圓形的液滴則撞擊力大。該時序控制單元15可為一電腦,但不限於此。 The droplet generating device 10 can further include a certain amount of the feeding unit 14 and a timing control unit 15, wherein the metering unit 14 can include a peristaltic pump 141 and a driving motor 142. The driving motor 142 is connected to the peristaltic pump 141 for driving the peristaltic pump 141 to provide a pressure to flow the fluid 131 in the pipeline 13, but the means for the quantitative feeding unit 14 is not limited thereto. Therefore, all can achieve the purpose of quantitative feeding. The timing control unit 15 is connected to the quantitative feeding unit 14, the fluid blocking unit 11 and the liquid droplet generating unit 12, respectively, and controls the quantitative feeding unit 14, the fluid blocking unit 11 and the droplet The respective driving time of the generating unit 12 is controlled to control the size, shape and ejection speed of the liquid droplet 134, for example, controlling the feeding speed and the time of the rotating disc intervention. When the speed is faster, the droplet is smaller, and the droplet is suddenly cut off. The wire will be drawn, and the droplets of the wire will have a small impact force when the 3D printing adhesive is applied, and the circular droplets will have a large impact force. The timing control unit 15 can be a computer, but is not limited thereto.

該液滴生成裝置10可更包含一基座16及一固定元件161,其中該基座16具有一溝槽162以容置該管線13,且該流體阻斷旋轉盤111及該拍擊外推旋轉盤121設置於該基座16之上。在該基座16、該流體阻斷旋轉盤111及該拍擊外推旋轉盤121之間的一第一相對位置關係被預先決定。基於 該第一相對位置關係,該固定元件161被使用以將該基座16固定於該第一馬達116及該第二馬達126上,其中該第一相對位置關係決定在該流體阻斷旋轉盤111、該拍擊外推旋轉盤121及該管線13之間的一第二相對位置關係,且該第二相對位置關係決定該管線13被該第二軸承122拍擊的一深度,該深度可調配該液滴牽絲的形狀。該固定元件161可為一螺絲,但不限於此。 The droplet generating device 10 can further include a base 16 and a fixing component 161, wherein the base 16 has a groove 162 for receiving the pipeline 13, and the fluid blocks the rotating disk 111 and the slap extrapolation A rotating disk 121 is disposed above the base 16. A first relative positional relationship between the base 16, the fluid blocking rotating disk 111, and the slamming extrapolation rotating disk 121 is predetermined. based on In the first relative positional relationship, the fixing member 161 is used to fix the base 16 to the first motor 116 and the second motor 126, wherein the first relative positional relationship is determined by the fluid blocking rotary disk 111. a second relative positional relationship between the slamming rotary disk 121 and the pipeline 13, and the second relative positional relationship determines a depth at which the pipeline 13 is slapped by the second bearing 122, the depth being adjustable The shape of the droplet is drawn. The fixing member 161 can be a screw, but is not limited thereto.

請參閱第一圖至第三圖(b),本發明第二實施例係提供一種液滴生成方法,該液滴生成方法包含下列步驟:提供一流體阻斷單元11,該流體阻斷單元11包括具有一第一軸承112之一流體阻斷旋轉盤111;隨著該流體阻斷旋轉盤111旋轉,該第一軸承112阻斷一管線13中之一流體131以產生體積固定之一部分流體132,其中該流體阻斷旋轉盤111可具有一第一上部113及一第一下部114,該第一軸承112可藉由螺絲或其他固定元件固定於該第一上部113及該第一下部114之間,固定的方法為使該第一軸承112固定於該流體阻斷旋轉盤111上的定點,且能以其中心為軸進行旋轉,如此該第一軸承112是以滾動的方式阻斷該管線13中之該流體131,因此能夠減少該第一軸承112的磨損。該流體阻斷旋轉盤111具有一或多對第一孔洞對115供固定該第一軸承112,該第一孔洞對115分別位於該第一上部113及該第一下部114,該第一孔洞對115的位置以能使該第一軸承112壓抵該管線13以至阻斷該管線13中之該流體131為準。 Referring to the first to third figures (b), the second embodiment of the present invention provides a droplet generating method comprising the steps of: providing a fluid blocking unit 11, the fluid blocking unit 11 A fluid blocking rotating disk 111 having a first bearing 112 is included; as the fluid blocks the rotating disk 111 from rotating, the first bearing 112 blocks a fluid 131 in a line 13 to produce a volume-fixed portion of the fluid 132. The fluid blocking rotary disk 111 can have a first upper portion 113 and a first lower portion 114. The first bearing 112 can be fixed to the first upper portion 113 and the first lower portion by screws or other fixing elements. Between 114, the fixing method is to fix the first bearing 112 to a fixed point on the fluid blocking rotating disk 111, and can rotate with its center as an axis, so that the first bearing 112 is blocked by rolling. The fluid 131 in the line 13 can thus reduce wear of the first bearing 112. The fluid blocking rotary disk 111 has one or more pairs of first hole pairs 115 for fixing the first bearing 112. The first hole pair 115 is located at the first upper portion 113 and the first lower portion 114, respectively. The position of the pair 115 is such that the first bearing 112 is pressed against the line 13 to block the fluid 131 in the line 13.

提供一液滴產生單元12,該液滴產生單元12包括具有一第二軸承122之一拍擊外推旋轉盤121;以及隨著該拍擊外推旋轉盤121旋轉,該第二軸承122拍擊並外推該管線13以從該部分流體132生成一液滴134,該液滴134可經由一針頭133生成,但不限於此。該拍擊外推旋轉盤121可具有一 第二上部123及一第二下部124,該第二軸承122可藉由螺絲或其他固定元件固定於該第二上部123及該第二下部124之間,固定的方法為使該第二軸承122固定於該拍擊外推旋轉盤121上的定點,且能以其中心為軸進行旋轉,如此該第二軸承122是以滾動的方式拍擊並外推該管線13,因此能夠減少該第二軸承122的磨損。該拍擊外推旋轉盤121具有一或多對第二孔洞對125供固定該第二軸承122,該第二孔洞對125的位置以能使該第二軸承122拍擊並外推該管線13但不至阻斷該管線13中之該流體131為準。 Providing a droplet generating unit 12, the droplet generating unit 12 including one of the second bearings 122 slamming the extrapolation rotating disc 121; and with the slamming extrapolating the rotating disc 121 rotating, the second bearing 122 is patted The line 13 is struck and extrapolated to generate a droplet 134 from the portion of fluid 132 that can be generated via a needle 133, but is not limited thereto. The slap extrapolation rotating disc 121 can have a The second upper portion 123 and the second lower portion 124 are fixed between the second upper portion 123 and the second lower portion 124 by screws or other fixing elements by fixing the second bearing 122. Fixed at a fixed point on the slap push-out rotary disk 121, and can be rotated about its center, such that the second bearing 122 slaps and pushes the line 13 in a rolling manner, thereby reducing the second Wear of the bearing 122. The slamming extrapolation rotary disk 121 has one or more pairs of second hole pairs 125 for fixing the second bearing 122, the second hole pair 125 being positioned to enable the second bearing 122 to slap and extrapolate the line 13 However, the fluid 131 in the line 13 is not blocked.

該第一軸承112與該流體阻斷旋轉盤111之一邊緣的距離可較該第二軸承122與該拍擊外推旋轉盤121之一邊緣的距離為近,差距可為0.5-1mm,但不限於此。 The distance between the first bearing 112 and one edge of the fluid blocking rotating disk 111 may be closer than the edge of the second bearing 122 to the edge of the slamming rotary disk 121, and the difference may be 0.5-1 mm, but the difference may be 0.5-1 mm, but Not limited to this.

在製造本發明之該流體阻斷旋轉盤111及該拍擊外推旋轉盤121時,可製造同時具有該第一孔洞對115及該第二孔洞對125的一旋轉盤,再視需要選擇該第一孔洞對115或該第二孔洞對125固定該第一軸承112或該第二軸承122,如此只需製造一種規格的旋轉盤即可得到該流體阻斷旋轉盤111及該拍擊外推旋轉盤121。 When manufacturing the fluid blocking rotating disk 111 of the present invention and the slamming external rotating disk 121, a rotating disk having the first hole pair 115 and the second hole pair 125 can be manufactured, and then selected as needed. The first hole pair 115 or the second hole pair 125 fixes the first bearing 112 or the second bearing 122, so that only one type of rotating disk can be manufactured to obtain the fluid blocking rotating disk 111 and the slamming extrapolation Rotating disk 121.

該流體阻斷單元11可更包括一第一馬達116,該液滴產生單元12可更包括一第二馬達126,且該方法更包括下列步驟:使該流體阻斷旋轉盤111之一第一中心部分117與該第一馬達116的一第一傳動軸118相接而受該第一馬達116帶動旋轉,隨著該流體阻斷旋轉盤111旋轉,該第一軸承112阻斷該管線13中之該流體131以產生體積固定之該部分流體132;以及使該拍擊外推旋轉盤121之一第二中心部分127與該第二馬達126的一第二傳動軸128相接而受該第二馬達126帶動旋轉,隨 著該拍擊外推旋轉盤121旋轉,該第二軸承122拍擊並外推該管線13以從該部分流體132生成該液滴134。該液滴生成方法可以阻斷一次,拍擊外推一次;亦可阻斷一次,拍擊外推多次。 The fluid blocking unit 11 may further include a first motor 116, the droplet generating unit 12 may further include a second motor 126, and the method further includes the step of causing the fluid to block one of the rotating disks 111 first The central portion 117 is coupled to a first drive shaft 118 of the first motor 116 and is rotated by the first motor 116. The first bearing 112 blocks the line 13 as the fluid blocks the rotation of the rotary disk 111. The fluid 131 is configured to generate the portion of the fluid 132 that is fixed in volume; and the second central portion 127 of the slamming extrapolation rotating disk 121 is coupled to a second transmission shaft 128 of the second motor 126. Two motors 126 drive rotation, along with The slap push-out rotary disk 121 rotates, and the second bearing 122 slaps and extrapolates the line 13 to generate the droplet 134 from the portion of the fluid 132. The droplet generation method can be blocked once, and the slap is extrapolated once; it can also be blocked once, and the slap is extrapolated multiple times.

該液滴生成方法可更包含下列步驟:提供一定量供料單元14,該定量供料單元14可包括一蠕動幫浦141及一驅動馬達142,其中該驅動馬達142連接於該蠕動幫浦141;使該驅動馬達142驅動該蠕動幫浦141以提供一壓力,從而使該流體131於該管線13內流動,但該定量供料單元14可採用的手段並不限於此,凡是能夠達到定量供料之目的均可;提供一時序控制單元15,該時序控制單元15分別與該定量供料單元14、該流體阻斷單元11及該液滴產生單元12連接;以及使該時序控制單元15藉由控制該定量供料單元14、該流體阻斷單元11及該液滴產生單元12的各別驅動時間來控制該液滴134之尺寸、形狀及噴射速度,例如控制供料速度的調配及旋轉盤介入的時間,速度較快則液滴較小,突然截斷則液滴會牽絲,牽絲的液滴在進行3D列印之黏著劑噴膠成型技術時撞擊力小,圓形的液滴則撞擊力大。該時序控制單元15可為一電腦,但不限於此。 The droplet generating method may further comprise the steps of: providing a quantity of the feeding unit 14, the metering unit 14 may include a peristaltic pump 141 and a driving motor 142, wherein the driving motor 142 is coupled to the peristaltic pump 141 The driving motor 142 is driven to drive the peristaltic pump 141 to provide a pressure to flow the fluid 131 in the pipeline 13. However, the means for the quantitative feeding unit 14 is not limited thereto, and any quantitative supply can be achieved. For the purpose of the material; a timing control unit 15 is provided, the timing control unit 15 is respectively connected to the quantitative feeding unit 14, the fluid blocking unit 11 and the liquid droplet generating unit 12; and the timing control unit 15 is borrowed The size, shape and ejection speed of the droplet 134 are controlled by controlling the respective driving times of the metering unit 14, the fluid blocking unit 11 and the droplet generating unit 12, for example, controlling the feeding speed and the rotation. When the disk is inserted, the droplets are smaller when the speed is faster, and the droplets are pulled when the film is suddenly cut off. The droplets of the wire are small in impact force when the 3D printing adhesive spray molding technology is used. then The impact force is large. The timing control unit 15 can be a computer, but is not limited thereto.

該液滴生成方法可更包含下列步驟:提供一基座16及一固定元件161,其中該基座具有一溝槽162以容置該管線13,且該流體阻斷旋轉盤111及該拍擊外推旋轉盤121設置於該基座16之上;預先決定在該基座16、該流體阻斷旋轉盤111及該拍擊外推旋轉盤121之間的一第一相對位置關係;以及基於該第一相對位置關係,使用該固定元件161以將該基座16固定於該第一馬達116及該第二馬達126上,其中該第一相對位置關係決定在該流體阻斷旋轉盤111、該拍擊外推旋轉盤121及該管線13之間的一第二相 對位置關係,且該第二相對位置關係決定該管線13被該第二軸承122拍擊的一深度,該深度可調配該液滴牽絲的形狀。該固定元件可為一螺絲,但不限於此。 The droplet generating method may further comprise the steps of: providing a susceptor 16 and a fixing member 161, wherein the pedestal has a groove 162 for accommodating the line 13, and the fluid blocks the rotating disk 111 and the slap An extrapolation rotating disc 121 is disposed on the base 16; a first relative positional relationship between the base 16, the fluid blocking rotating disc 111 and the tapping extrapolating rotating disc 121 is determined in advance; The first relative positional relationship is used to fix the base 16 to the first motor 116 and the second motor 126, wherein the first relative positional relationship determines the fluid blocking rotary disk 111, The slap pushes a second phase between the rotating disk 121 and the pipeline 13 For a positional relationship, the second relative positional relationship determines a depth at which the line 13 is struck by the second bearing 122, the depth of which can be adapted to the shape of the droplet. The fixing member may be a screw, but is not limited thereto.

請參閱第四圖,本發明第三實施例係提供一種液滴生成裝置20,用以控制供應一流體231之一管線23之液滴供應,其中該管線23具一流入端A及一流出端B。該液滴生成裝置20包含一流體阻斷單元21,用以阻斷該流體231自該流入端A額外供應該管線;以及一液滴產生單元22,以一預定壓力在該流體阻斷單元21及該流出端B間擠壓該管線23,以從該流出端B生成一液滴234。該流體阻斷單元21包括一流體阻斷旋轉盤211,該流體阻斷旋轉盤211具有一第一軸承212,隨著該流體阻斷旋轉盤211旋轉,該第一軸承212阻斷該管線23中之該流體231以產生體積固定之一部分流體232。該液滴產生單元22包括一拍擊外推旋轉盤221,該拍擊外推旋轉盤221具有一第二軸承222,隨著該拍擊外推旋轉盤221旋轉,該第二軸承222拍擊並外推該管線23以從該部分流體232生成該液滴234。 Referring to the fourth figure, a third embodiment of the present invention provides a droplet generating apparatus 20 for controlling the supply of droplets of a line 23 supplying a fluid 231 having an inflow end A and a first-class outlet. B. The droplet generating device 20 includes a fluid blocking unit 21 for blocking the fluid 231 from additionally supplying the line from the inflow end A; and a droplet generating unit 22 at the fluid blocking unit 21 at a predetermined pressure. The line 23 is squeezed between the outflow end B to generate a droplet 234 from the outflow end B. The fluid blocking unit 21 includes a fluid blocking rotating disk 211 having a first bearing 212 that blocks the line 23 as the fluid blocks the rotating disk 211 from rotating. The fluid 231 is fixed in volume to form a portion of the fluid 232. The droplet generating unit 22 includes a tapping extrapolation rotating disc 221 having a second bearing 222, and the second bearing 222 is slammed as the tapping externally rotates the rotating disc 221 The line 23 is extrapolated to generate the droplet 234 from the portion of the fluid 232.

請參閱第五圖,本發明第四實施例係提供一種液滴生成裝置30,用以控制供應一流體331之一管線33之液滴供應,其中該管線33具一流入端C及一流出端D。該液滴生成裝置30包含一流體供應切斷單元31,用以切斷該流體331之供應該管線33;以及一液滴產生單元32,以一預定壓力在該流體供應切斷單元31及該流出端D間擠壓該管線33,以從該流出端D生成一液滴334。 Referring to the fifth embodiment, a fourth embodiment of the present invention provides a droplet generating device 30 for controlling the supply of droplets to a line 33 of a fluid 331 having an inflow end C and a first-class outlet. D. The liquid droplet generating device 30 includes a fluid supply cutting unit 31 for cutting off the supply of the fluid 331 to the line 33, and a liquid droplet generating unit 32 at the fluid supply cutting unit 31 and the predetermined pressure. The line 33 is squeezed between the outflow ends D to generate a droplet 334 from the outflow end D.

本發明之液滴生成裝置用於具生物分子的溶液或任何具有黏性的液體,可使其生成體積較小的液滴以利於後續的應用,例如在進行 3D列印之黏著劑噴膠成型技術時增加成品的精度。且本發明之液滴生成裝置係作用於管線,不會直接接觸管線中的液體,因此較為衛生而利於通過醫療審核。此外,藉由管線之管璧散熱,更可調整管璧的厚度使其散熱效果更佳,因此不會影響包含生物因子之液體的生物活性。 The droplet generating device of the present invention is used for a solution with biomolecules or any viscous liquid, which can be made to generate smaller droplets for subsequent applications, for example, 3D printing of adhesive spray molding technology increases the precision of the finished product. Moreover, the droplet generating device of the present invention acts on the pipeline and does not directly contact the liquid in the pipeline, so it is hygienic and facilitates medical examination. In addition, by the heat dissipation of the tube, the thickness of the tube can be adjusted to better the heat dissipation effect, so that the biological activity of the liquid containing the biological factor is not affected.

實驗例Experimental example

以本發明之液滴生成裝置製備血漿液滴:以本發明之液滴生成裝置製備血漿液滴,所使用者為0.16mm的針頭。結果成功的將原本直徑250-300μm的血漿液滴縮小到200μm。以製得之血漿液滴做為3D列印之黏著劑噴膠成型技術中的成型用溶液來製造人工骨材,最後得到精度高又具有生物活性的人工骨材。 Plasma droplets were prepared using the droplet generating apparatus of the present invention: plasma droplets were prepared by the droplet generating apparatus of the present invention, and the user was a needle of 0.16 mm. As a result, the original plasma droplets having a diameter of 250-300 μm were successfully reduced to 200 μm. The obtained plasma droplets are used as a forming solution in the 3D printing adhesive spray molding technology to manufacture artificial bone materials, and finally an artificial bone material with high precision and biological activity is obtained.

實施例Example

1.一種液滴生成裝置,包含:一流體阻斷單元,包括一流體阻斷旋轉盤,該流體阻斷旋轉盤具有一第一軸承,隨著該流體阻斷旋轉盤旋轉,該第一軸承阻斷一管線中之一流體以產生體積固定之一部分流體;以及一液滴產生單元,包括一拍擊外推旋轉盤,該拍擊外推旋轉盤具有一第二軸承,隨著該拍擊外推旋轉盤旋轉,該第二軸承拍擊並外推該管線以從該部分流體生成一液滴。 A droplet generating apparatus comprising: a fluid blocking unit comprising a fluid blocking rotating disk, the fluid blocking rotating disk having a first bearing, the first bearing being rotated as the fluid blocks the rotating disk Blocking one of the fluids in a line to produce a volume of a portion of the fluid; and a droplet generating unit comprising a slamming extrapolated rotating disk having a second bearing along with the slap The rotary disk is extrapolated and the second bearing slaps and extrapolates the line to generate a droplet from the portion of the fluid.

2.如實施例1所述之液滴生成裝置,其中該流體阻斷單元更包括一第一馬達,該液滴產生單元更包括一第二馬達,其中:該流體阻斷旋轉盤之一第一中心部分與該第一馬達的一第一傳動軸相接而可受該第一馬達帶動旋轉,隨著該流體阻斷旋轉盤旋轉,該第一 軸承阻斷該管線中之該流體以產生體積固定之該部分流體;以及該拍擊外推旋轉盤之一第二中心部分與該第二馬達的一第二傳動軸相接而可受該第二馬達帶動旋轉,隨著該拍擊外推旋轉盤旋轉,該第二軸承拍擊並外推該管線以從該部分流體生成一液滴。 2. The droplet generating device of embodiment 1, wherein the fluid blocking unit further comprises a first motor, the droplet generating unit further comprising a second motor, wherein: the fluid blocks one of the rotating disks a central portion is coupled to a first drive shaft of the first motor to be rotatable by the first motor, the first being rotated as the fluid blocks the rotation of the rotary disk The bearing blocks the fluid in the line to produce the portion of the fluid that is fixed in volume; and the second central portion of the slamming extrapolated rotating disk is coupled to a second drive shaft of the second motor to be subjected to the The two motors drive the rotation, and as the slap pushes the rotary disk to rotate, the second bearing slaps and extrapolates the line to generate a droplet from the portion of the fluid.

3.如實施例1-2所述之液滴生成裝置,更包含一定量供料單元及一時序控制單元,其中:該定量供料單元包括一蠕動幫浦及一驅動馬達,該驅動馬達連接於該蠕動幫浦,用以驅動該蠕動幫浦提供一壓力,以使該流體於該管線內流動;以及該時序控制單元分別與該定量供料單元、該流體阻斷單元及該液滴產生單元連接,並藉由控制該定量供料單元、該流體阻斷單元及該液滴產生單元的各別驅動時間來控制該液滴之尺寸、形狀及噴射速度。 3. The droplet generating device of embodiment 1-2, further comprising a quantity feeding unit and a timing control unit, wherein: the metering unit comprises a peristaltic pump and a driving motor, and the driving motor is connected The peristaltic pump is configured to drive the peristaltic pump to provide a pressure to flow the fluid in the pipeline; and the timing control unit and the dosing unit, the fluid blocking unit and the droplet are respectively generated The cells are connected and the size, shape and ejection speed of the droplets are controlled by controlling the respective driving times of the dosing unit, the fluid blocking unit and the droplet generating unit.

4.如實施例1-3所述之液滴生成裝置,更包含一基座及一固定元件,其中:該基座具有一溝槽以容置該管線,且該流體阻斷旋轉盤及該拍擊外推旋轉盤設置於該基座之上;在該基座、該流體阻斷旋轉盤及該拍擊外推旋轉盤之間的一第一相對位置關係被預先決定;以及基於該第一相對位置關係,該固定元件被使用以將該基座固定於該第一馬達及該第二馬達上,其中該第一相對位置關係決定在該流體阻斷旋轉盤、該拍擊外推旋轉盤及該管線之間的一第二相對位置關係,且該第二相對位置關係決定該管線被該第二軸承拍擊的一深度。 4. The droplet generating device of embodiment 1-3, further comprising a base and a fixing component, wherein: the base has a groove to receive the pipeline, and the fluid blocks the rotating disk and the a tapping extrapolation rotating disc is disposed on the base; a first relative positional relationship between the base, the fluid blocking rotating disc and the tapping extrapolating rotating disc is predetermined; and based on the a relative positional relationship, the fixing element is used to fix the base to the first motor and the second motor, wherein the first relative positional relationship determines that the fluid blocks the rotating disk, and the slap extrapolates A second relative positional relationship between the disk and the line, and the second relative positional relationship determines a depth at which the line is tapped by the second bearing.

5.一種液滴生成方法,包含下列步驟: 提供一流體阻斷單元,該流體阻斷單元包括具有一第一軸承之一流體阻斷旋轉盤;隨著該流體阻斷旋轉盤旋轉,該第一軸承阻斷一管線中之一流體以產生體積固定之一部分流體;提供一液滴產生單元,該液滴產生單元包括具有一第二軸承之一拍擊外推旋轉盤;以及隨著該拍擊外推旋轉盤旋轉,該第二軸承拍擊並外推該管線以從該部分流體生成一液滴。 5. A method of generating a droplet comprising the steps of: Providing a fluid blocking unit including a fluid blocking rotating disk having a first bearing; the first bearing blocks a fluid in a line to generate as the fluid blocks rotation of the rotating disk One part of the fluid is fixed in volume; a droplet generating unit is provided, the droplet generating unit includes a slap-out extrapolated rotating disc having a second bearing; and the second bearing is shot by extrapolating the rotating disc with the slap The line is tapped and extrapolated to generate a droplet from the portion of the fluid.

6.如實施例5所述之方法,其中該流體阻斷單元更包括一第一馬達,該液滴產生單元更包括一第二馬達,且該方法更包括下列步驟:使該流體阻斷旋轉盤之一第一中心部分與該第一馬達的一第一傳動軸相接而受該第一馬達帶動旋轉,隨著該流體阻斷旋轉盤旋轉,該第一軸承阻斷該管線中之該流體以產生體積固定之該部分流體;以及使該拍擊外推旋轉盤之一第二中心部分與該第二馬達的一第二傳動軸相接而受該第二馬達帶動旋轉,隨著該拍擊外推旋轉盤旋轉,該第二軸承阻斷該管線中之該流體以產生體積固定之該部分流體。 6. The method of embodiment 5, wherein the fluid blocking unit further comprises a first motor, the droplet generating unit further comprises a second motor, and the method further comprises the step of: blocking the rotation of the fluid a first central portion of the disk is coupled to a first drive shaft of the first motor and is rotated by the first motor. The first bearing blocks the line in the pipeline as the fluid blocks rotation of the rotary disk The fluid is configured to generate the portion of the fluid that is fixed in volume; and the second central portion of the slap extrapolated rotating disk is coupled to a second drive shaft of the second motor for rotation by the second motor, The slap pushes the rotary disk to rotate, the second bearing blocks the fluid in the line to produce a portion of the fluid that is fixed in volume.

7.如實施例5-6所述之方法,更包含下列步驟:提供一定量供料單元,該定量供料單元包括一蠕動幫浦及一驅動馬達,其中該驅動馬達連接於該蠕動幫浦;使該驅動馬達驅動該蠕動幫浦以提供一壓力,從而使該流體於該管線內流動;提供一時序控制單元,該時序控制單元分別與該定量供料單元、該 流體阻斷單元及該液滴產生單元連接,以及使該時序控制單元藉由控制該定量供料單元、該流體阻斷單元及該液滴產生單元的各別驅動時間來控制該液滴之尺寸、形狀及噴射速度。 7. The method of any of embodiments 5-6, further comprising the steps of: providing a quantity of a supply unit comprising a peristaltic pump and a drive motor, wherein the drive motor is coupled to the peristaltic pump Causing the drive motor to drive the peristaltic pump to provide a pressure to cause the fluid to flow within the line; providing a timing control unit, the timing control unit and the dosing unit, respectively The fluid blocking unit and the droplet generating unit are connected, and the timing control unit controls the size of the droplet by controlling respective driving times of the quantitative feeding unit, the fluid blocking unit and the droplet generating unit , shape and jet speed.

8.如實施例5-7所述之方法,更包含下列步驟:提供一基座及一固定元件,其中該基座具有一溝槽以容置該管線,且該流體阻斷旋轉盤及該拍擊外推旋轉盤設置於該基座之上;預先決定在該基座、該流體阻斷旋轉盤及該拍擊外推旋轉盤之間的一第一相對位置關係;以及基於該第一相對位置關係,使用該固定元件以將該基座固定於該第一馬達及該第二馬達上,其中該第一相對位置關係決定在該流體阻斷旋轉盤、該拍擊外推旋轉盤及該管線之間的一第二相對位置關係,且該第二相對位置關係決定該管線被該第二軸承拍擊的一深度。 8. The method of embodiments 5-7, further comprising the steps of: providing a base and a securing member, wherein the base has a groove to receive the line, and the fluid blocks the rotating disk and the a tapping extrapolation rotating disc is disposed on the base; determining a first relative positional relationship between the base, the fluid blocking rotating disc and the tapping extrapolating rotating disc; and based on the first a relative positional relationship, the fixing element is used to fix the base to the first motor and the second motor, wherein the first relative positional relationship is determined by the fluid blocking rotating disk, the tapping extrapolating rotating disk, and A second relative positional relationship between the lines, and the second relative positional relationship determines a depth at which the line is tapped by the second bearing.

9.一種液滴生成裝置,用以控制供應一流體之一管線之液滴供應,其中該管線具一流入端及一流出端,該液滴生成裝置包含:一流體阻斷單元,用以阻斷該流體自該流入端額外供應該管線;以及一液滴產生單元,以一預定壓力在該流體阻斷單元及該流出端間擠壓該管線,以從該流出端生成一液滴。 A droplet generating device for controlling supply of a droplet of a line supplying a fluid, wherein the line has an inflow end and a first-class outlet, the droplet generating device comprising: a fluid blocking unit for blocking The fluid is additionally supplied from the inflow end; and a droplet generating unit presses the line between the fluid blocking unit and the outflow end at a predetermined pressure to generate a droplet from the outflow end.

10.如實施例9所述之液滴生成裝置,其中:該流體阻斷單元包括一流體阻斷旋轉盤,該流體阻斷旋轉盤具有一第一軸承,隨著該流體阻斷旋轉盤旋轉,該第一軸承阻斷該管線中之該流體以產生體積固定之一部分流體。 10. The droplet generating device of embodiment 9, wherein: the fluid blocking unit comprises a fluid blocking rotating disk having a first bearing that blocks rotation of the rotating disk as the fluid blocks The first bearing blocks the fluid in the line to create a volume of a portion of the fluid.

11.如實施例9-10所述之液滴生成裝置,其中:該液滴產生單元包括一拍擊外推旋轉盤,該拍擊外推旋轉盤具有一第二軸承,隨著該拍擊外推旋轉盤旋轉,該第二軸承拍擊並外推該管線以從該部分流體生成一液滴。 11. The droplet generating device of embodiment 9-10, wherein: the droplet generating unit comprises a slap extrapolation rotating disk, the slamming extrapolating rotating disk having a second bearing, with the slap The rotary disk is extrapolated and the second bearing slaps and extrapolates the line to generate a droplet from the portion of the fluid.

12.一種液滴生成裝置,用以控制供應一流體之一管線之液滴供應,其中該管線具一流入端及一流出端,該液滴生成裝置包含:一流體供應切斷單元,用以切斷該流體之供應該管線;以及一液滴產生單元,以一預定壓力在該流體供應切斷單元及該流出端間擠壓該管線,以從該流出端生成一液滴。 12. A droplet generating device for controlling supply of a droplet of a line supplying a fluid, wherein the line has an inflow end and a first-stage outlet, the droplet generating device comprising: a fluid supply cutting unit for Cutting the supply of the fluid to the line; and a droplet generating unit that presses the line between the fluid supply shut-off unit and the outflow end at a predetermined pressure to generate a droplet from the outflow end.

Claims (10)

一種液滴生成裝置,包含:一流體阻斷單元,包括一流體阻斷旋轉盤,該流體阻斷旋轉盤具有一第一軸承,隨著該流體阻斷旋轉盤旋轉,該第一軸承阻斷一管線中之一流體以產生體積固定之一部分流體;以及一液滴產生單元,包括一拍擊外推旋轉盤,該拍擊外推旋轉盤具有一第二軸承,隨著該拍擊外推旋轉盤旋轉,該第二軸承拍擊並外推該管線以從該部分流體生成一液滴。 A droplet generating device comprising: a fluid blocking unit comprising a fluid blocking rotating disk, the fluid blocking rotating disk having a first bearing, the first bearing blocking as the fluid blocks rotation of the rotating disk a fluid in a line to generate a volume of a portion of the fluid; and a droplet generating unit comprising a slap extrapolation rotating disk, the slamming extrapolating rotating disk having a second bearing, extrapolated with the slap The rotating disk rotates and the second bearing slaps and extrapolates the line to create a droplet from the portion of the fluid. 如申請專利範圍第3項所述之液滴生成裝置,其中該流體阻斷單元更包括一第一馬達,該液滴產生單元更包括一第二馬達,其中:該流體阻斷旋轉盤之一第一中心部分與該第一馬達的一第一傳動軸相接而可受該第一馬達帶動旋轉,隨著該流體阻斷旋轉盤旋轉,該第一軸承阻斷該管線中之該流體以產生體積固定之該部分流體;以及該拍擊外推旋轉盤之一第二中心部分與該第二馬達的一第二傳動軸相接而可受該第二馬達帶動旋轉,隨著該拍擊外推旋轉盤旋轉,該第二軸承拍擊並外推該管線以從該部分流體生成一液滴。 The liquid droplet generating device of claim 3, wherein the fluid blocking unit further comprises a first motor, the liquid droplet generating unit further comprising a second motor, wherein: the fluid blocks one of the rotating disks The first central portion is coupled to a first drive shaft of the first motor to be rotatable by the first motor, and the first bearing blocks the fluid in the pipeline as the fluid blocks rotation of the rotary disk Generating a portion of the fluid that is fixed in volume; and the second central portion of the slamming extrapolated rotating disk is coupled to a second drive shaft of the second motor to be rotated by the second motor, along with the slap The rotary disk is extrapolated and the second bearing slaps and extrapolates the line to generate a droplet from the portion of the fluid. 如申請專利範圍第1項所述之液滴生成裝置,更包含一定量供料單元及一時序控制單元,其中:該定量供料單元包括一蠕動幫浦及一驅動馬達,該驅動馬達連接於該蠕動幫浦,用以驅動該蠕動幫浦提供一壓力,以使該流體於該管線內流動;以及該時序控制單元分別與該定量供料單元、該流體阻斷單元及該液滴 產生單元連接,並藉由控制該定量供料單元、該流體阻斷單元及該液滴產生單元的各別驅動時間來控制該液滴之尺寸、形狀及噴射速度。 The droplet generating device of claim 1, further comprising a quantity feeding unit and a timing control unit, wherein: the metering unit comprises a peristaltic pump and a driving motor, and the driving motor is connected to The peristaltic pump is configured to drive the peristaltic pump to provide a pressure to flow the fluid in the pipeline; and the timing control unit and the dosing unit, the fluid blocking unit and the droplet respectively A unit connection is generated, and the size, shape, and ejection speed of the droplet are controlled by controlling respective driving times of the metering unit, the fluid blocking unit, and the droplet generating unit. 如申請專利範圍第1項所述之液滴生成裝置,更包含一基座及一固定元件,其中:該基座具有一溝槽以容置該管線,且該流體阻斷旋轉盤及該拍擊外推旋轉盤設置於該基座之上;在該基座、該流體阻斷旋轉盤及該拍擊外推旋轉盤之間的一第一相對位置關係被預先決定;以及基於該第一相對位置關係,該固定元件被使用以將該基座固定於該第一馬達及該第二馬達上,其中該第一相對位置關係決定在該流體阻斷旋轉盤、該拍擊外推旋轉盤及該管線之間的一第二相對位置關係,且該第二相對位置關係決定該管線被該第二軸承拍擊的一深度。 The liquid droplet generating device of claim 1, further comprising a base and a fixing component, wherein: the base has a groove for receiving the pipeline, and the fluid blocks the rotating disk and the beat Putting an extrapolating rotating disc on the base; a first relative positional relationship between the base, the fluid blocking rotating disc and the tapping extrapolating rotating disc is predetermined; and based on the first a relative positional relationship, the fixing member is used to fix the base to the first motor and the second motor, wherein the first relative positional relationship is determined by the fluid blocking rotating disk, the slamming extrapolating rotating disk And a second relative positional relationship between the lines, and the second relative positional relationship determines a depth at which the line is tapped by the second bearing. 一種液滴生成方法,包含下列步驟:提供一流體阻斷單元,該流體阻斷單元包括具有一第一軸承之一流體阻斷旋轉盤;隨著該流體阻斷旋轉盤旋轉,該第一軸承阻斷一管線中之一流體以產生體積固定之一部分流體;提供一液滴產生單元,該液滴產生單元包括具有一第二軸承之一拍擊外推旋轉盤;以及隨著該拍擊外推旋轉盤旋轉,該第二軸承拍擊並外推該管線以從該部分流體生成一液滴。 A droplet generating method comprising the steps of: providing a fluid blocking unit comprising a fluid blocking rotating disk having a first bearing; the first bearing as the fluid blocks rotation of the rotating disk Blocking a fluid in a line to produce a volume of a portion of the fluid; providing a droplet generating unit comprising a slap extrapolating rotating disk having a second bearing; and along with the slap The rotary disk is rotated and the second bearing slaps and extrapolates the line to generate a droplet from the portion of the fluid. 如申請專利範圍第5項所述之方法,其中該流體阻斷單元更包括一第一馬 達,該液滴產生單元更包括一第二馬達,且該方法更包括下列步驟:使該流體阻斷旋轉盤之一第一中心部分與該第一馬達的一第一傳動軸相接而受該第一馬達帶動旋轉,隨著該流體阻斷旋轉盤旋轉,該第一軸承阻斷該管線中之該流體以產生體積固定之該部分流體;以及使該拍擊外推旋轉盤之一第二中心部分與該第二馬達的一第二傳動軸相接而受該第二馬達帶動旋轉,隨著該拍擊外推旋轉盤旋轉,該第二軸承阻斷該管線中之該流體以產生體積固定之該部分流體。 The method of claim 5, wherein the fluid blocking unit further comprises a first horse The droplet generating unit further includes a second motor, and the method further comprises the step of: causing the fluid to block the first central portion of the rotating disk to be in contact with a first drive shaft of the first motor The first motor drives rotation, the first bearing blocks the fluid in the pipeline to generate a volume of the portion of the fluid as the fluid blocks the rotation of the rotating disk; and the slap is extrapolated to one of the rotating disks The second central portion is coupled to a second drive shaft of the second motor for rotation by the second motor, and the second bearing blocks the fluid in the pipeline to generate the rotation of the rotary disk as the slap is pushed The portion of the fluid that is fixed in volume. 如申請專利範圍第5項所述之方法,更包含下列步驟:提供一定量供料單元,該定量供料單元包括一蠕動幫浦及一驅動馬達,其中該驅動馬達連接於該蠕動幫浦;使該驅動馬達驅動該蠕動幫浦以提供一壓力,從而使該流體於該管線內流動;提供一時序控制單元,該時序控制單元分別與該定量供料單元、該流體阻斷單元及該液滴產生單元連接,以及使該時序控制單元藉由控制該定量供料單元、該流體阻斷單元及該液滴產生單元的各別驅動時間來控制該液滴之尺寸、形狀及噴射速度。 The method of claim 5, further comprising the steps of: providing a quantity of the feeding unit, the metering unit comprising a peristaltic pump and a driving motor, wherein the driving motor is coupled to the peristaltic pump; Causing the drive motor to drive the peristaltic pump to provide a pressure to flow the fluid within the line; providing a timing control unit, the timing control unit and the dosing unit, the fluid blocking unit and the liquid, respectively The droplet generating unit is connected, and the timing control unit controls the size, shape and ejection speed of the droplet by controlling respective driving times of the metering unit, the fluid blocking unit and the droplet generating unit. 如申請專利範圍第5項所述之方法,更包含下列步驟:提供一基座及一固定元件,其中該基座具有一溝槽以容置該管線,且該流體阻斷旋轉盤及該拍擊外推旋轉盤設置於該基座之上;預先決定在該基座、該流體阻斷旋轉盤及該拍擊外推旋轉盤之間的一第一相對位置關係;以及基於該第一相對位置關係,使用該固定元件以將該基座固定於該第 一馬達及該第二馬達上,其中該第一相對位置關係決定在該流體阻斷旋轉盤、該拍擊外推旋轉盤及該管線之間的一第二相對位置關係,且該第二相對位置關係決定該管線被該第二軸承拍擊的一深度。 The method of claim 5, further comprising the steps of: providing a base and a fixing component, wherein the base has a groove for receiving the pipeline, and the fluid blocks the rotating disk and the shooting Putting an extrapolated rotating disc on the base; predetermining a first relative positional relationship between the base, the fluid blocking rotating disc and the tapping extrapolating rotating disc; and based on the first relative Positional relationship, using the fixing element to fix the base to the first a second motor and the second motor, wherein the first relative positional relationship determines a second relative positional relationship between the fluid blocking rotating disk, the slamming extrapolating rotating disk and the pipeline, and the second relative position The positional relationship determines a depth at which the pipeline is tapped by the second bearing. 一種液滴生成裝置,用以控制供應一流體之一管線之液滴供應,其中該管線具一流入端及一流出端,該液滴生成裝置包含:一流體阻斷單元,用以阻斷該流體自該流入端額外供應該管線,其中該流體阻斷單元包括一流體阻斷旋轉盤,該流體阻斷旋轉盤具有一第一軸承,隨著該流體阻斷旋轉盤旋轉,該第一軸承阻斷該管線中之該流體以產生體積固定之一部分流體;以及一液滴產生單元,以一預定壓力在該流體阻斷單元及該流出端間擠壓該管線,以從該流出端生成一液滴。 A droplet generating device for controlling supply of a droplet of a line supplying a fluid, wherein the line has an inflow end and a first-class outlet, the droplet generating device comprising: a fluid blocking unit for blocking the The fluid additionally supplies the line from the inflow end, wherein the fluid blocking unit includes a fluid blocking rotating disk having a first bearing, the first bearing being rotated as the fluid blocks the rotating disk Blocking the fluid in the line to produce a volume of a portion of the fluid; and a droplet generating unit for compressing the line between the fluid blocking unit and the outflow end at a predetermined pressure to generate a flow from the outflow end Droplet. 如申請專利範圍第9項所述之液滴生成裝置,其中:該液滴產生單元包括一拍擊外推旋轉盤,該拍擊外推旋轉盤具有一第二軸承,隨著該拍擊外推旋轉盤旋轉,該第二軸承拍擊並外推該管線以從該部分流體生成一液滴。 The liquid droplet generating device of claim 9, wherein: the liquid droplet generating unit comprises a tapping extrapolation rotating disc, the tapping extrapolating rotating disc having a second bearing, along with the tapping The rotary disk is rotated and the second bearing slaps and extrapolates the line to generate a droplet from the portion of the fluid.
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