TWI372053B - Combination drug - Google Patents

Combination drug

Info

Publication number: TWI372053B
Authority: TW; Taiwan
Prior art keywords: combination drug; drug; combination
Prior art date: 2005-09-15

Application number

TW095134039A

Other languages

English (en)

Other versions

TW200744597A (en

Inventor

Ki Whan Hong

Tomohiro Yoshikawa

Original Assignee

Otsuka Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-09-15

Filing date

2006-09-14

Publication date

2012-09-11

2006-09-14 Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd

2007-12-16 Publication of TW200744597A publication Critical patent/TW200744597A/zh

2012-09-11 Application granted granted Critical

2012-09-11 Publication of TWI372053B publication Critical patent/TWI372053B/zh

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Cardiology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Hospice & Palliative Care (AREA)
Biochemistry (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

TW095134039A 2005-09-15 2006-09-14 Combination drug TWI372053B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US71695405P	2005-09-15	2005-09-15
US76177506P	2006-01-25	2006-01-25

Publications (2)

Publication Number	Publication Date
TW200744597A TW200744597A (en)	2007-12-16
TWI372053B true TWI372053B (en)	2012-09-11

Family

ID=37420867

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW095134039A TWI372053B (en)	2005-09-15	2006-09-14	Combination drug

Country Status (21)

Country	Link
US (2)	US8580818B2 (zh)
EP (2)	EP1942895B1 (zh)
JP (2)	JP5179354B2 (zh)
KR (1)	KR101299320B1 (zh)
AR (1)	AR057520A1 (zh)
AU (1)	AU2006289752B2 (zh)
BR (1)	BRPI0616223A2 (zh)
CA (1)	CA2620296C (zh)
CY (1)	CY1112716T1 (zh)
DK (1)	DK1942895T3 (zh)
ES (1)	ES2378896T3 (zh)
HK (1)	HK1122996A1 (zh)
IL (1)	IL189751A0 (zh)
MY (1)	MY145787A (zh)
NO (1)	NO20081811L (zh)
PL (1)	PL1942895T3 (zh)
PT (1)	PT1942895E (zh)
RU (1)	RU2411945C2 (zh)
SG (1)	SG165379A1 (zh)
TW (1)	TWI372053B (zh)
WO (1)	WO2007032557A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR065588A1 (es) *	2007-03-09	2009-06-17	Otsuka Pharma Co Ltd	Un medicamento para tratar enfermedad pulmonar obstructiva cronica
AR070816A1 (es) *	2008-03-14	2010-05-05	Otsuka Pharma Co Ltd	Farmaco de combinacion para tratar trastornos vasculares

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5535019A (en)	1978-09-01	1980-03-11	Otsuka Pharmaceut Co Ltd	Carbostyryl derivative
JPH04193836A (ja) *	1990-11-26	1992-07-13	Banyu Pharmaceut Co Ltd	抗高脂血症剤
JPH107590A (ja)	1996-06-24	1998-01-13	Chugai Pharmaceut Co Ltd	脳循環障害後遺症または脳虚血後の脳神経障害の治療剤
FR2751540B1 (fr)	1996-07-26	1998-10-16	Sanofi Sa	Composition pharmaceutique antithrombotique
EP0946178A4 (en)	1996-09-18	2003-05-07	Merck & Co Inc	COMBINATION THERAPY TO REDUCE THE RISKS OF HEART CIRCULAR DISEASES
US6245797B1 (en)	1997-10-22	2001-06-12	Merck & Co., Inc.	Combination therapy for reducing the risks associated with cardio-and-cerebrovascular disease
WO1999024400A1 (en)	1997-11-10	1999-05-20	Vyrex Corporation	Probucol esters and uses thereof
US6235311B1 (en)	1998-03-18	2001-05-22	Bristol-Myers Squibb Company	Pharmaceutical composition containing a combination of a statin and aspirin and method
AU5965399A (en)	1998-10-12	2000-05-01	Andreas Bockelmann	Pharmaceutically active composition
AU4671101A (en)	2000-04-10	2001-10-23	Malcolm R. Law	Formulation for the prevention of cardiovascular disease
US20020115728A1 (en) *	2000-09-05	2002-08-22	Roland Stocker	Compositions and methods for treating cardiovascular disorders
RU2003126186A (ru) *	2001-01-26	2005-03-10	Шеринг Корпорейшн (US)	Комбинации ингибитора (ингибиторов) всасывания стерина с сердечно-сосудистым агентом (агентами), предназначенные для лечения патологических состояний сосудов
US6576256B2 (en)	2001-08-28	2003-06-10	The Brigham And Women's Hospital, Inc.	Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin
JP2003192573A (ja) *	2001-12-25	2003-07-09	Otsuka Pharmaceut Factory Inc	経口ゲル製剤
US20030181461A1 (en)	2002-01-25	2003-09-25	Lautt Wilfred Wayne	Use of phosphodiesterase antagonists to treat insulin resistance
US6743806B2 (en) *	2002-10-23	2004-06-01	Otsuka Pharmaceutical Company, Limited	Active oxygen scavenger
JP2005232059A (ja) *	2004-02-18	2005-09-02	Iichiro Shimomura	低アディポネクチン血症予防・治療剤
PL1894576T3 (pl)	2005-06-08	2011-10-31	Kowa Co	Nowy środek do obniżania poziomu triglicerydów
JP4193836B2 (ja)	2005-10-24	2008-12-10	ブラザー工業株式会社	インク噴射装置の製造方法

2006
- 2006-09-14 EP EP06810355A patent/EP1942895B1/en not_active Not-in-force
- 2006-09-14 KR KR1020087008859A patent/KR101299320B1/ko not_active IP Right Cessation
- 2006-09-14 EP EP10177619A patent/EP2275106A1/en not_active Withdrawn
- 2006-09-14 AR ARP060104020A patent/AR057520A1/es unknown
- 2006-09-14 RU RU2008114512/15A patent/RU2411945C2/ru not_active IP Right Cessation
- 2006-09-14 US US12/065,619 patent/US8580818B2/en not_active Expired - Fee Related
- 2006-09-14 BR BRPI0616223-1A patent/BRPI0616223A2/pt not_active IP Right Cessation
- 2006-09-14 PT PT06810355T patent/PT1942895E/pt unknown
- 2006-09-14 JP JP2008514987A patent/JP5179354B2/ja not_active Expired - Fee Related
- 2006-09-14 PL PL06810355T patent/PL1942895T3/pl unknown
- 2006-09-14 AU AU2006289752A patent/AU2006289752B2/en not_active Ceased
- 2006-09-14 MY MYPI20080610A patent/MY145787A/en unknown
- 2006-09-14 SG SG201006668-6A patent/SG165379A1/en unknown
- 2006-09-14 ES ES06810355T patent/ES2378896T3/es active Active
- 2006-09-14 DK DK06810355.5T patent/DK1942895T3/da active
- 2006-09-14 WO PCT/JP2006/318675 patent/WO2007032557A1/en active Application Filing
- 2006-09-14 TW TW095134039A patent/TWI372053B/zh not_active IP Right Cessation
- 2006-09-14 CA CA2620296A patent/CA2620296C/en not_active Expired - Fee Related
2008
- 2008-02-25 IL IL189751A patent/IL189751A0/en unknown
- 2008-04-14 NO NO20081811A patent/NO20081811L/no not_active Application Discontinuation
2009
- 2009-01-09 HK HK09100257.9A patent/HK1122996A1/xx not_active IP Right Cessation
2012
- 2012-04-20 CY CY20121100376T patent/CY1112716T1/el unknown
- 2012-09-11 JP JP2012199804A patent/JP5603393B2/ja not_active Expired - Fee Related
2013
- 2013-10-21 US US14/059,368 patent/US20140045889A1/en not_active Abandoned

Also Published As

Publication number	Publication date
BRPI0616223A2 (pt)	2011-06-14
MY145787A (en)	2012-04-30
PL1942895T3 (pl)	2012-07-31
JP2013014605A (ja)	2013-01-24
JP5179354B2 (ja)	2013-04-10
CY1112716T1 (el)	2016-02-10
RU2008114512A (ru)	2009-10-20
AU2006289752B2 (en)	2011-06-09
AR057520A1 (es)	2007-12-05
JP2009508804A (ja)	2009-03-05
HK1122996A1 (en)	2009-06-05
TW200744597A (en)	2007-12-16
CA2620296A1 (en)	2007-03-22
CA2620296C (en)	2013-10-22
EP1942895B1 (en)	2012-02-01
US20140045889A1 (en)	2014-02-13
IL189751A0 (en)	2008-12-29
WO2007032557A1 (en)	2007-03-22
RU2411945C2 (ru)	2011-02-20
US8580818B2 (en)	2013-11-12
EP2275106A1 (en)	2011-01-19
KR20080049822A (ko)	2008-06-04
KR101299320B1 (ko)	2013-09-03
PT1942895E (pt)	2012-03-29
DK1942895T3 (da)	2012-03-05
EP1942895A1 (en)	2008-07-16
ES2378896T3 (es)	2012-04-18
US20090176826A1 (en)	2009-07-09
JP5603393B2 (ja)	2014-10-08
AU2006289752A1 (en)	2007-03-22
SG165379A1 (en)	2010-10-28
NO20081811L (no)	2008-04-14

Publication	Publication Date	Title
AP2008004533A0 (en)	2008-08-31	Pharmaceutical combination
LT1912671T (lt)	2017-12-11	Vaisto konjugatai, turintys gliukoronido linkerį
GB0501999D0 (en)	2005-03-09	Pharmaceutical compounds
GB0419849D0 (en)	2004-10-13	Pharmaceutical combination
EP1844804A4 (en)	2010-05-05	SYRINGE
EP1849490A4 (en)	2009-09-16	SYRINGE
GB0500643D0 (en)	2005-02-23	Medicaments
IL197883A0 (en)	2009-12-24	Combination drug
ZA200804666B (en)	2010-01-27	Pharmaceutical combination
GB0512643D0 (en)	2005-07-27	Pharmaceutical compounds
GB0511204D0 (en)	2005-07-06	Medicaments
EP1853258A4 (en)	2008-05-07	DRUGS
GB0507003D0 (en)	2005-05-11	Therapeutic
TWI372053B (en)	2012-09-11	Combination drug
GB0518720D0 (en)	2005-10-19	Therapeutic combination
GB0512246D0 (en)	2005-07-27	Novel pharmaceutical
GB2437466B (en)	2009-06-17	Syringes
GB0501475D0 (en)	2005-03-02	Pharmaceutical compounds
GB0417777D0 (en)	2004-09-15	Pharmaceutical combination
GB0502541D0 (en)	2005-03-16	Medicament
GB0500691D0 (en)	2005-02-23	Pharmaceutical combinations
GB0500826D0 (en)	2005-02-23	Pharmaceutical use
GB0418567D0 (en)	2004-09-22	Pharmaceutical combination
GB0514260D0 (en)	2005-08-17	Medicaments
GB0515315D0 (en)	2005-08-31	Pharmaceutical agents

Legal Events

Date	Code	Title	Description
2016-06-11	MM4A	Annulment or lapse of patent due to non-payment of fees