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TW324010B - Macrolides compound used as anti-inflammatory agent - Google Patents

Macrolides compound used as anti-inflammatory agent

Info

Publication number
TW324010B
TW324010B TW083104878A TW83104878A TW324010B TW 324010 B TW324010 B TW 324010B TW 083104878 A TW083104878 A TW 083104878A TW 83104878 A TW83104878 A TW 83104878A TW 324010 B TW324010 B TW 324010B
Authority
TW
Taiwan
Prior art keywords
hydroxy
represents hydrogen
hydrogen
group
represent oxo
Prior art date
Application number
TW083104878A
Other languages
Chinese (zh)
Inventor
R C Murty Bulusu A
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of TW324010B publication Critical patent/TW324010B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A compound of formula I: I in which: R represents a following group, in which or R7 represents a hydroxy or 2-hydroxylethoxy protected by tert-butyldimethylsilicon, or represents isopropylhydroxyloxy or chlorine, and R7a represents hydrogen; or R7 and R7a jointly represent oxo; R8 represents methoxyl; and R2 represents hydrogen, isopropylhydroxyloxy or hydroxyl, and a single bond or double bond exists between two carbon atoms connected by a dotted line; R3 represents ethyl or allyl; or R4 represents hydrogen or hydroxy and R4a represents hydrogen; or R4 and R4a jointly represent oxo; or R5 represents hydroxy and R5a represents hydrogen; or R5 and R5a jointly represent oxo; and A represents one group in -CH(OR6)-CH2-(CH2)n- or -CH=CH-(CH2)n-, hence, in which the -CH2- group is connected to a carbon atom, R6 represents C1-4 alkyl, and n represents 1 or 2; its form is an ionized form or a salt form.
TW083104878A 1993-05-27 1994-05-28 Macrolides compound used as anti-inflammatory agent TW324010B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939310969A GB9310969D0 (en) 1993-05-27 1993-05-27 Organic compounds

Publications (1)

Publication Number Publication Date
TW324010B true TW324010B (en) 1998-01-01

Family

ID=10736229

Family Applications (1)

Application Number Title Priority Date Filing Date
TW083104878A TW324010B (en) 1993-05-27 1994-05-28 Macrolides compound used as anti-inflammatory agent

Country Status (4)

Country Link
EC (1) ECSP941092A (en)
GB (1) GB9310969D0 (en)
PL (1) PL176409B1 (en)
TW (1) TW324010B (en)

Also Published As

Publication number Publication date
ECSP941092A (en) 1994-12-15
PL176409B1 (en) 1999-05-31
GB9310969D0 (en) 1993-07-14

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