TW208010B - - Google Patents
Info
- Publication number
- TW208010B TW208010B TW081107641A TW81107641A TW208010B TW 208010 B TW208010 B TW 208010B TW 081107641 A TW081107641 A TW 081107641A TW 81107641 A TW81107641 A TW 81107641A TW 208010 B TW208010 B TW 208010B
- Authority
- TW
- Taiwan
- Prior art keywords
- medicaments
- triazaspirodecanones
- triazaspirodecanonemethylchromans
- methylchromans
- reacting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Photoreceptors In Electrophotography (AREA)
- Enzymes And Modification Thereof (AREA)
- Pyrane Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4135473A DE4135473A1 (de) | 1991-10-28 | 1991-10-28 | Triazaspirodecanon-methylchromane |
Publications (1)
Publication Number | Publication Date |
---|---|
TW208010B true TW208010B (zh) | 1993-06-21 |
Family
ID=6443565
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW081107641A TW208010B (zh) | 1991-10-28 | 1992-09-26 |
Country Status (19)
Country | Link |
---|---|
US (1) | US6060482A (zh) |
EP (1) | EP0539803B1 (zh) |
JP (1) | JP3257708B2 (zh) |
KR (1) | KR930007945A (zh) |
AT (1) | ATE175414T1 (zh) |
AU (1) | AU650792B2 (zh) |
CA (1) | CA2081256A1 (zh) |
CZ (1) | CZ322492A3 (zh) |
DE (2) | DE4135473A1 (zh) |
DK (1) | DK0539803T3 (zh) |
ES (1) | ES2125879T3 (zh) |
FI (1) | FI924848A (zh) |
GR (1) | GR3029450T3 (zh) |
HU (1) | HUT64068A (zh) |
IL (1) | IL103546A0 (zh) |
MX (1) | MX9205869A (zh) |
NO (1) | NO923974L (zh) |
TW (1) | TW208010B (zh) |
ZA (1) | ZA928290B (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19522088A1 (de) * | 1995-06-19 | 1997-01-02 | Bayer Ag | Benzisothiazolyl-substituierte Aminomethylchromane |
CA2226058C (en) * | 1997-01-30 | 2008-01-29 | F. Hoffmann-La Roche Ag | 8-substituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives |
DE60033071T2 (de) * | 1999-12-06 | 2007-08-23 | Euro-Celtique S.A. | Triazospiroverbindungen mit nociceptin-rezeptoraffinität |
JPWO2003040382A1 (ja) * | 2001-11-09 | 2005-03-03 | 株式会社カネカ | 光学活性クロマン誘導体の製造法および中間体 |
US6995168B2 (en) * | 2002-05-31 | 2006-02-07 | Euro-Celtique S.A. | Triazaspiro compounds useful for treating or preventing pain |
CN100402529C (zh) * | 2002-09-09 | 2008-07-16 | 詹森药业有限公司 | 用于治疗orl-1受体介导疾病的羟基烷基取代的1,3,8-三氮杂螺[4,5]癸-4-酮衍生物 |
US20070229303A1 (en) * | 2003-10-16 | 2007-10-04 | Collier Willliam R | Fluid Level Detector and Alarm Apparatus |
US20060178390A1 (en) * | 2004-08-02 | 2006-08-10 | Alfonzo Jordan | 1,3,8-Triazaspiro[4,5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders |
WO2008067167A1 (en) * | 2006-11-28 | 2008-06-05 | Janssen Pharmaceutica N.V. | Salts of 3-(3-amino-2-(r)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one |
JP5490677B2 (ja) * | 2007-04-09 | 2014-05-14 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 不安及び鬱病の処置のためのorl−1受容体リガンドとしての1,3,8−三置換−1,3,8−トリアザ−スピロ[4.5]デカン−4−オン誘導体 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3826835A (en) * | 1971-01-08 | 1974-07-30 | Ciba Geigy Corp | 8-benzofurylmethyl-1,3,8-triazaspiro(4,5)decanes as neuroleptics |
US4689330A (en) * | 1985-04-15 | 1987-08-25 | Janssen Pharmaceutica N.V. | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines |
US4749702A (en) * | 1985-04-15 | 1988-06-07 | Janssen Pharmaceutica N. V. | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines |
US4826848A (en) * | 1985-04-15 | 1989-05-02 | Janssen Pharmaceutica N.V. | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines |
US4957928A (en) * | 1986-06-26 | 1990-09-18 | Ciba-Geigy Corporation | Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds |
DE3901814A1 (de) * | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
DE3831888A1 (de) * | 1988-09-20 | 1990-03-29 | Troponwerke Gmbh & Co Kg | Arzneimittel zur behandlung von apoplexia cerebri |
DE4039631A1 (de) * | 1990-12-12 | 1992-06-17 | Troponwerke Gmbh & Co Kg | Neuroprotektive kombination |
-
1991
- 1991-10-28 DE DE4135473A patent/DE4135473A1/de not_active Withdrawn
-
1992
- 1992-09-26 TW TW081107641A patent/TW208010B/zh active
- 1992-10-07 AU AU26265/92A patent/AU650792B2/en not_active Ceased
- 1992-10-13 MX MX9205869A patent/MX9205869A/es unknown
- 1992-10-13 NO NO92923974A patent/NO923974L/no unknown
- 1992-10-15 AT AT92117606T patent/ATE175414T1/de not_active IP Right Cessation
- 1992-10-15 DK DK92117606T patent/DK0539803T3/da active
- 1992-10-15 ES ES92117606T patent/ES2125879T3/es not_active Expired - Lifetime
- 1992-10-15 DE DE59209607T patent/DE59209607D1/de not_active Expired - Fee Related
- 1992-10-15 EP EP92117606A patent/EP0539803B1/de not_active Expired - Lifetime
- 1992-10-19 US US07/963,165 patent/US6060482A/en not_active Expired - Fee Related
- 1992-10-23 CA CA002081256A patent/CA2081256A1/en not_active Abandoned
- 1992-10-26 IL IL103546A patent/IL103546A0/xx unknown
- 1992-10-26 CZ CS923224A patent/CZ322492A3/cs unknown
- 1992-10-26 FI FI924848A patent/FI924848A/fi unknown
- 1992-10-27 ZA ZA928290A patent/ZA928290B/xx unknown
- 1992-10-27 KR KR1019920019792A patent/KR930007945A/ko not_active Application Discontinuation
- 1992-10-28 HU HU9203382A patent/HUT64068A/hu unknown
- 1992-10-28 JP JP31279892A patent/JP3257708B2/ja not_active Expired - Fee Related
-
1999
- 1999-02-19 GR GR990400535T patent/GR3029450T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU650792B2 (en) | 1994-06-30 |
EP0539803B1 (de) | 1999-01-07 |
DK0539803T3 (da) | 1999-08-30 |
ES2125879T3 (es) | 1999-03-16 |
GR3029450T3 (en) | 1999-05-28 |
DE4135473A1 (de) | 1993-04-29 |
JPH05222040A (ja) | 1993-08-31 |
FI924848A0 (fi) | 1992-10-26 |
JP3257708B2 (ja) | 2002-02-18 |
AU2626592A (en) | 1993-04-29 |
MX9205869A (es) | 1993-04-01 |
CA2081256A1 (en) | 1993-04-29 |
ATE175414T1 (de) | 1999-01-15 |
US6060482A (en) | 2000-05-09 |
EP0539803A1 (de) | 1993-05-05 |
CZ322492A3 (en) | 1993-07-14 |
FI924848A (fi) | 1993-04-29 |
IL103546A0 (en) | 1993-03-15 |
DE59209607D1 (de) | 1999-02-18 |
HUT64068A (en) | 1993-11-29 |
HU9203382D0 (en) | 1993-01-28 |
ZA928290B (en) | 1993-05-04 |
NO923974L (no) | 1993-04-29 |
KR930007945A (ko) | 1993-05-20 |
NO923974D0 (no) | 1992-10-13 |
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