TW201545776A - Infiltration type medical thin film patch - Google Patents

Abstract

An infiltration type medical thin film patch is disclosed, which includes a thin film patch, a medicament gluing layer and a release layer. The thin film patch is in a patch-like shape having an upper surface and a lower surface, and two assisting patches are arranged on the lower surface of the thin film patch. A mixture of a medical pressure sensitive adhesive and a nanometer-sized medicament is coated on a lower surface of the thin film patch so as to form a medicament gluing layer, and the release layer is attached on the medicament gluing layer. In the application of the infiltration type medical thin film patch, the thin film patch is attached on a patient's skin after the release layer is tore, and then the thin film patch can be smoothly and closely attached on the patient's skin after the assisting patch is slightly pressed. After that the thin film patch to be smoothly and closely attached on the patient's skin, the assisting patches can be removed from the thin film patch. The nanometer-sized medicament can be took in the patient' body in infiltration manner through contacting the patient's skin, capable of attaining the therapeutic effect. By using the infiltration to allow the patient's skin to directly take in the medicament, instead of oral administration or medicament practice, the disclosed infiltration type medical thin film patch can be applied to a continuous treatment with excellent effect. Moreover, with the design of two assisting patches and two release layers, the attachment process of the thin film patch can be smoothly performed without medicament sticking problems to user's hands, and the thin film patch can be attached on the skin for a long time due to air permeability with less tendency to come off from the skin or even to disturb the patient. Hence, the disclosed infiltration type medical thin film patch is provided with practical effectiveness and progressiveness.

Description

Osmotic medical film patch

The present invention relates to a permeable pharmaceutical film patch which is prepared by mixing a nano-treated drug with a viscous medical pressure sensitive adhesive and then applied to a film patch to form a drug bonding layer. When in use, the film patch is attached to the body, so that the nanochemical agent can be absorbed into the patient through the skin contact, and the effect of continuous treatment can be achieved.

According to the traditional medical treatment, there are mainly three types of administration methods currently used for patients: (1) Oral medicine method: the medicine is directly orally administered to the patient in the form of pills, tablets, capsules or syrup; (2) Subcutaneous injection method: the medicament is directly injected into the patient by the syringe; (3) Skin absorption method: the medicine is absorbed by the medicated cloth or the smear method.

However, although the three methods can apply the agent to the patient, there are the following defects:

(1) Oral medicine method, because of the need to take medicine on time, patients often ignore the time of medication, and forget to take medicine, so often can not reach the therapeutic effect, and for most patients, especially elderly and young patients often for oral medication There is a problem with dysphagia, so oral administration is obviously not ideal.

(2) The subcutaneous injection method is to directly inject the medicament into the patient's body with a syringe. Although it is quite fast, it requires a professional nurse to apply the injection, which is quite inconvenient for the patient, and also needs to pay attention to the medication time, young The patient is more repellent for the injection.

(3) Skin absorption method: medicated cloth or smear method can absorb the medicine through the skin. The method of application usually only applies to skin wounds or skin diseases, and the medicated cloth is only sold in the market. It can be used to treat the symptoms of soreness in the body, and it is impossible to use other medicines to achieve the effect of the treatment. The traditional medicine cloth sticks to the skin for too long, which may cause skin irritation and discomfort.

The inventor specializes in medical related research and is well aware of the traditional medical treatment. Missing, so it is the best way to solve the problem, and with its own professional and years of work experience, coupled with several trials, corrections and improvements, finally the invention of the permeable medical film patch was born.

The present invention relates to a permeable medical film patch comprising: a film patch, a drug bonding layer, a release layer and an auxiliary patch. The film patch is a sheet made of acrylic pressure-sensitive adhesive tape, which has an upper surface and a lower surface; firstly, the required medicine is prepared, and then the medicine is subjected to nano-treatment, and is viscous. After the medical pressure sensitive glue is mixed, it is coated on the lower surface of the film patch to form a chemical bonding layer; the release layer is a two-piece design, and the two release layers are attached to the chemical bonding layer to avoid the drug staining. Sticky or polluted. In use, after peeling off two pieces of the release layer, the film patch is attached to the skin of the patient, and then the auxiliary patch is removed, and the auxiliary patch can make the film patch more smooth and fit; The glue layer is directly contacted with the skin of the patient by the film patch, so that the nano-chemical agent can be continuously absorbed into the patient through the skin contact, and the effect of long-term administration can be achieved.

Therefore, the object of the present invention is to use the osmotic medicinal film patch technology to mix the nano-chemical agent with the medical sensation pressure glue, and then use the osmosis method to enable the patient to directly absorb the medicine by using the skin without oral or application. When the medicine is applied, the best effect of the treatment can be achieved without causing inconvenience to the patient, and the film patch has a breathable effect, and the adhesion effect is excellent, and the adhesion can be continuously adhered to the patient's skin for more than 72 hours, and Providing uninterrupted continuous drug delivery; and the permeable medical film patch has a tearing end on the end faces of the two release layers and the second auxiliary patch, in addition to avoiding sticking to the hand when pasting, The film patch can be evenly attached to the surface of the skin, and is not easy to fall off.

[this creation]

10‧‧‧film patch

101‧‧‧ upper surface

102‧‧‧lower surface

11‧‧‧Pharmaceutical glue layer

12‧‧‧Fractal layer

120‧‧‧First release layer

121‧‧‧Second release layer

1201‧‧‧Tear end

1211‧‧‧Tear end

13‧‧‧Auxiliary patch

130‧‧‧First Auxiliary Patch

131‧‧‧Second Auxiliary Patch

1301‧‧‧Tear end

1311‧‧‧Tear end

1‧‧‧Pharmaceutical preparation

2‧‧‧Pharmaceuticalization

3‧‧‧Mixed viscose

4‧‧‧ Coating film

14‧‧‧Physician prescription medication

15‧‧‧General medicine

20‧‧‧Nanochemical Molecules

30‧‧‧ medical pressure sensitive adhesive

31‧‧‧Glue

5‧‧‧ skin

Figure 1 is a perspective exploded view of the present invention.

Figure 2 is a schematic flow diagram of the present invention.

Figure 3 is a flow chart of the preparation of the medicament of the present invention.

Figure 4 is a flow chart of the pharmaceutical nanocrystallization of the present invention.

Figure 5 is a flow chart of the hybrid adhesive of the present invention.

Figure 6 is a flow chart of the coating film of the present invention.

Figure 7 is a schematic view showing the use of the present invention.

First, referring to Fig. 1, an exploded perspective view of the present invention is composed of a film patch 10, a drug bonding layer 11, a release layer 12, and an auxiliary patch 13. The film patch 10 is made of acrylic pressure sensitive adhesive tape, and has an upper surface 101 and a lower surface 102; the chemical bonding layer 11 is composed of a nano-chemical agent and a viscous medical pressure sensitive adhesive (not shown in the figure) After being mixed, it is applied to the lower surface 102 of the film patch 10; the release layer 12 is attached to the drug bonding layer 11 having the first release layer 120 and the second release layer 121, and respectively The end surface is provided with a tearing end 1201 and 1211. The auxiliary patch 13 has a first auxiliary patch 130 and a second auxiliary patch 131 attached to the upper surface 101 of the film patch 10 and respectively on one end surface thereof. Tear-stretched ends 1301 and 1311 are provided.

Next, please refer to FIG. 2, which is a schematic flow chart of the present invention. The permeable medical film patch of the present invention has four stages:

(1) Pharmacy preparation 1: The medicinal or nutritional supplement suitable for the treatment of various symptoms is prepared for use.

(2) Nanocrystallization of the drug 2: All the drugs were subjected to nanocrystallization to form a molecular chemical agent.

(3) Mixed viscose 3: The nano-mineral molecular agent and the viscous medical pressure sensitive glue are mixed into a glued agent.

(4) Coating film 4: The glue agent is uniformly applied to the inner surface of the film patch.

Next, please refer to FIG. 3 , which is a flow chart of the preparation of the medicament of the present invention. The first stage of the preparation of the medicament is prepared according to the patient's symptoms, such as the prescription medicine 14 or the general medicine 15 , and the preparation is completed.

Next, referring to Fig. 4, it is a flow chart of the drug nanocrystallization according to the present invention. The second phase of the drug is a drug-reducing drug 14 or a general drug 15 after being nano-sized to become a nano-chemical agent 20 .

Next, please refer to FIG. 5 , which is a flow chart of the mixed adhesive of the present invention. The mixed viscose 3 is uniformly mixed with the medical sensitizing gel 30 after nanocrystallization to form a glue. Medicament 31.

Please refer to FIG. 6 again, which is a flow chart of the coating film of the present invention. In the fourth stage, the uniformly mixed glued agent 31 is applied onto the lower surface 102 of the gas permeable film patch 10 to form a chemically bonded layer 11 (not shown).

When in use, please refer to FIG. 7 , which is a schematic diagram of the use of the present invention. First, the first release layer 120 is peeled off by the finger pinch end 1201 (please refer to FIG. 1 again), by the first The support of the auxiliary patch 130 can keep the film patch 10 flat, and then the adhesive layer 11 of the film patch 10 is attached to the patient's skin 5, and then the first auxiliary patch 130 is lightly pressed to make the film paste. One end of the piece 10 is smoothly applied to the skin 5, and then the first auxiliary patch 130 is removed by the tearing end 1301; then the second release layer 121 is peeled off by gently pulling the tearing end 1211, and then the second is pressed. After the auxiliary patch 131 is attached to the film patch 10, the second auxiliary patch 131 is removed by the tearing end 1311, and the film patch 10 can be completely attached to the patient's skin 5 at this time. By directly contacting the drug bonding layer 11 with the patient's skin 5, the nano-medicated agent can be absorbed into the patient through the contact of the skin 5 in an osmotic manner, and the therapeutic effect can be achieved.

Therefore, the present invention utilizes the osmotic medicinal film patch technology to mix the nano-chemical agent with the medical sensation pressure glue, and the osmotic method can be used to enable the patient to directly absorb the medicine by using the skin without oral or medicinal application. The best effect of treatment can be achieved, and the method of completely subverting traditional medical administration is a major breakthrough.

Therefore, the osmotic medical film patch technology of the present invention has the following advantages:

(1) The use of osmotic medicinal film patches instead of oral medicinal agents can achieve the effect of continuous administration, especially for elderly and young patients who often have difficulty swallowing oral medications.

(2) The use of osmotic medicinal film patches instead of subcutaneous injection of pharmaceuticals does not require professional nursing personnel to apply injections to reduce the discomfort of patients with injections.

(3) The film patch has a breathable effect, and the medical pressure sensitive adhesive has high adhesion, excellent skin adhesion, does not fall in water, peels off no residue, does not cause skin too tight, and has two slices The design of the release layer and the auxiliary patch has an excellent adhesion effect and can be continuously adhered to the patient's skin for more than 72 hours, and can provide uninterrupted continuous treatment.

In summary, the present invention uses a permeable pharmaceutical film patch technology to mix a nanochemical agent with a medical type pressure sensitive adhesive, and uses a osmotic method to enable the patient to directly absorb the drug by using the skin. The agent can achieve the best therapeutic effect without oral or medicinal application, and the film patch has a breathable effect, can be continuously adhered to the patient's skin for a long time, does not fall off, and can provide uninterrupted continuous The therapeutic effect is a highly progressive invention, and it is not found in the publication. It has already met the patent requirements of the invention and has filed a patent application according to law.

10‧‧‧film patch

101‧‧‧ upper surface

102‧‧‧lower surface

11‧‧‧Pharmaceutical glue layer

12‧‧‧Fractal layer

120‧‧‧First release layer

121‧‧‧Second release layer

1201‧‧‧Tear end

1211‧‧‧Tear end

13‧‧‧Auxiliary patch

130‧‧‧First Auxiliary Patch

131‧‧‧Second Auxiliary Patch

1301‧‧‧Tear end

1311‧‧‧Tear end

Claims (8)

The invention relates to a permeable medical film patch, which mainly comprises a film patch, a drug bonding layer, a two-parting layer and two auxiliary patches, wherein the film patch is a sheet made of acrylic pressure sensitive adhesive tape. The patch has an upper surface and a lower surface; the chemical bonding layer is mixed with a viscous medical pressure sensitive adhesive and applied to the lower surface of the film patch; the release layer is attached to the drug gluing Below the layer, there is a first release layer and a second release layer, and each of the end faces is provided with a tear-off end; the auxiliary patch has a first auxiliary patch and a second auxiliary patch attached to the film The top surface of the patch is provided with a tear-off end on one of the end faces, which comprises at least the following steps: (1) preparation of the medicament; (2) nanocrystallization of the medicament; (3) mixing of the adhesive; (4) coating Cloth film. The osmotic medicinal film patch of claim 1, wherein the medicinal preparation step is to prepare a drug suitable for various symptomatic effects. The osmotic pharmaceutical film patch according to claim 1, wherein the drug nanocrystallization step is to treat the finished drug into a nano-sized molecular agent. The osmotic pharmaceutical film patch according to claim 1, wherein the mixed adhesive step is a mixture of a nano-sized molecular agent and a viscous medical type pressure sensitive adhesive. The osmotic pharmaceutical film patch of claim 1, wherein the coating film step uniformly applies the glue agent to the lower surface of the film patch. The osmotic pharmaceutical film patch according to claim 1, wherein the nanochemical agent of the drug bonding layer can be a general medicine, a doctor prescription drug or other therapeutic drugs. The permeable medical film patch of claim 1, wherein one of the end faces of the two auxiliary patches is provided with a tear-off end. The permeable medical film patch of claim 1, wherein one of the end faces of the two release layers is provided with a tear-off end.