TW201404425A - Photodynamic therapy device - Google Patents

Abstract

A photodynamic therapy device can be attached over user's head in a similar way as wearing glasses, such that skin can be treated from diseases or for a cosmetic purpose.

Description

Photodynamic therapy device

The present invention relates to a photodynamic therapy device, and more particularly to a photodynamic therapy device for treating the skin and hair of the forehead, face and head.

The principle of early photodynamic therapy is to use a specific wavelength of light to illuminate the photosensitizer absorbed by the body tissue, and the excited photosensitizer transmits energy to the surrounding oxygen to form a highly active singlet oxygen, singlet. Oxygen reacts with adjacent biomacromolecules to produce cytotoxic effects, which in turn leads to cell damage and even apoptosis. Therefore, early photodynamic therapy mainly kills bad cells, especially cancer cells.

In addition, if the topical use of pentaaminolevulinic acid (5-ALA) or other photoactivated drugs, and then exposed to light sources, can change the molecules, thereby improving the phenomenon of skin aging. Although skin exposure to ultraviolet light can be damaging; however, many clinical studies have shown that visible light, infrared lasers and other light sources can cause positive changes in the skin. Currently, there are many clinically used light-sensitive ingredients (photosensitizers) to promote some light-based treatments, especially molecular changes between epithelial and dermal cells. Clinical evidence suggests that photodynamic therapy is associated with stimulation of epithelial hyperplasia, and the results show a 5-fold increase in Ki67 (P < .05) and a 1.4-fold increase in epithelial thickness (P < .05); The time was nearly 70 times (P < .05), indicating that the epithelium was hurt. Evidence for increased collagen includes increased type 1 procollagen message RNA (2.65 fold; P < .05), type 3 procollagen message RNA (3.32 fold; P < .05), type 1 procollagen Protein (2.42 fold; P < .05).

The use of photodynamic therapy for skin blemishes, in many clinical studies, shows that skin sputum smear sensitizing drugs and then LED red light, the effect is excellent. An ALA, a collaboration between the Institute of Optoelectronic Biomedical Sciences, the Department of Plastic Surgery, and the Department of Dermatology, National Taiwan University In the photodynamic therapy study of common sputum, a total of 30 patients with fingers, feet, and facial paralysis were treated. The complete cure rate was 80%, and the partial cure rate was only 20%. According to the information provided by Dr. Jianxiong Fei, the attending physician of the Department of Surgery of National Taiwan University, the cure method is to apply the pentamine valeric acid (ALA) sensitizing drug to the sputum for three hours before using the luminescent diode ( LED) The red light is illuminated for ten minutes, triggering the effect. For the next two to three weeks, the sputum lesion will fall off and leave no trace.

The devices currently used in photodynamic therapy are mainly large-scale machines, which means that people who are treated or who want to have skin repairs must go to a hospital with such large equipment to receive treatment. In addition, although the main machine can have a high luminous flux output, the area of the irradiation is also large, and it is not the most efficient way to repair a small area of the skin. Therefore, when it is desired to repair and cosmetic the local skin in daily life, the small hand-held device is a better device.

Some manufacturers have also developed electronic masks that use the light-emitting elements attached to the face to illuminate the skin of the user's face at close range. However, because on the one hand, it must be attached to the user's skin, so you must choose a material with low sensitivity. On the other hand, you must pay attention to the problem of heat dissipation to avoid heat damage to the skin. Moreover, the manner in which the volts are applied causes the light to concentrate around the illuminating elements and does not uniformly illuminate the user's skin.

However, whether it is a large machine or a small handheld device, users should avoid the light from illuminating the user's eyes to avoid discomfort in the eyes and the chance of retinal injury. Clinically, when performing light therapy on the face, the user is required to wear goggles at the same time to protect the eyes. Although this ensures safety, the user is unable to use the eyes, which increases the inconvenience of use. Accordingly, the present invention is primarily directed to providing a user with a simpler and safer light treatment device for treating the forehead, head and facial skin or hair of the eye.

In view of the above-mentioned invention background, in order to meet the needs of industrial interests and In view of the above, the present invention provides a new photodynamic therapy device that mainly includes a photodynamic therapy device body, a fixture, and a shading device. In the body of the photodynamic therapy device described above, there is a circuit having a plurality of illuminants such as light emitting diodes on one side and a driving circuit for controlling a plurality of illuminants. The aforementioned fixing device allows the main body of the photodynamic treatment device to be worn on the user's head like a pair of glasses or a helmet, and is not required to be fixed by the user's hand during the treatment. The above-mentioned shading device is made of a soft material, and on the other hand, it can be attached to the skin around the eyes of the user, so that the light emitted by the illuminator is blocked, and the retina cannot be damaged by the user's eyes, so the user does not need to wear additional care. Eyepieces, you can open your eyes and use one side to do other things. On the other hand, the shading device can also keep a certain distance between the skin and the main body of the photodynamic treatment device, so that the light of the illuminant on the main body can be more uniformly irradiated on the skin of the user, and the heat of the main body can not be damaged to the skin.

In addition, the photodynamic therapy device body of the present invention can be connected to a rechargeable battery to provide the power required by the plurality of illuminators, so that the user can freely move without using the power cord when using the treatment device.

The photodynamic therapy device body of the present invention can also be coupled to a circuit controller, which can include device switches and timing devices that can control the charging and discharging of the rechargeable battery and the illumination of the respective illuminators. The circuit controller can also include a connector that can be connected to other power supply devices, such as mains, transformers, or a general sequence of computers.

The direction of the invention discussed herein is a photodynamic therapy device. In order to thoroughly understand the present invention, a detailed structure and its composition will be set forth in the following description. Obviously, the practice of the present invention is not limited to the specific details familiar to those skilled in the art of photodynamic therapy devices. On the other hand, well-known components or steps are not described in detail to avoid unnecessarily limiting the invention. The preferred embodiments of the present invention will be described in detail below, but the present invention may be widely practiced in other embodiments and the scope of the present invention is not limited by the detailed description. Limited, which is subject to the scope of the patents that follow.

The invention provides a simple photodynamic treatment device, and the user can perform photodynamic therapy or skin beauty even when working in an office.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Referring to the first embodiment, a body 10 of a photodynamic therapy device of the present invention includes a circuit and a driving circuit. The photodynamic treatment device body 10 is provided with a plurality of illuminants 30 as a light source for photodynamic therapy. The photodynamic therapy device body 10 is coupled to a headband 60 that bypasses the user's head to allow the photodynamic therapy device body 10 to be secured to the user's head. The headband 60 can be constructed of an elastic material and can be adjusted in length and elasticity. The photodynamic treatment device body 10 is further connected with a light shielding pad 50 composed of a soft material having no light transmissive property. The light shielding pad 50 is located below the photodynamic treatment device main body 10 and can be closely attached to the user's skin (as shown in the figure). As shown in the second part, the light of the illuminator 30 is blocked, and it is impossible to directly hit the user's eyes and cause injury.

The photodynamic therapy device body 10 of the present embodiment is further connected to a circuit controller 40, which comprises a device switch and timing device. The circuit controller 40 can control the charging and discharging of the rechargeable battery 20 via the electric wire 31, and the respective illuminants. 30 illuminating time and illuminating brightness. The circuit controller 40 also includes a connector 70 that can be connected to other power supply devices, such as a mains, transformer, or computer universal serial port (USB), etc., to provide the power required by the illuminator 30, and the other. Aspects provide the power required to charge the rechargeable battery 20.

Further, the photodynamic treatment device main body 10 of the present embodiment is connected to a rechargeable battery 20 such as a lithium polymer battery. After the user charges the rechargeable battery 20, the connection line can be removed, and the power of the rechargeable battery 20 can supply the power required by the plurality of illuminators 30 to use the device. However, the rechargeable battery 20 is not an essential component of the present invention, and the photodynamic therapy device body 10 can be connected to a general battery or an external power source for use. The rechargeable battery 20 and the circuit controller 40 can also be combined into a single component.

Another embodiment of the invention is shown in the third figure. Photodynamic therapy device The illumination range of the main body 10 covers the entire face of the user, so that the ring-shaped light shielding pad 50 can surround the eyes, and a headband 60 that bypasses the head of the user can be used to allow the photodynamic treatment device body 10 to be attached. It is fixed to the user's face while the light emitted by the illuminator 30 cannot be directly directed to the eyes. Therefore, when the user uses the device, the eyes can still be opened without special protection.

Another embodiment of the invention is shown in the fifth figure. The illumination range of the photodynamic therapy device body 10 of this embodiment covers the entire head. Since the illuminators 30 are all located above the eyes, the light-shielding pad 50 may be located at the lower edge of the front half of the photodynamic therapy device body 10 as in the first embodiment, plus a bypassing of the user's head. The headband 60 allows the photodynamic treatment device body 10 to be attached to the user's head while allowing the light emitted by the illuminator 30 to be directed to the eye. Therefore, when the user uses the device, the eyes can still be opened without special protection. In addition, the embodiment further includes a plurality of spacers 80. The spacer 80 can keep the illuminant 30 at a certain distance from the skin of the user, and on the other hand, the light of the illuminant 30 can be uniformly illuminated to the user's skin. On the other hand, the heat of the illuminator 30 can also be prevented from damaging the skin

In the present invention, the illuminant 30 can be a light-emitting diode that emits red light and blue light, and the light source emitted by the light source 30 is usually in a narrow spectrum, does not generate high heat, and does not burn the skin. A blue light emitting diode is used which, when the wavelength of the light is near about 415 nm, matches the peak of light absorption of the P. acnes metabolite. When the chemical deactivating process of the acne bacillus metabolite is stimulated, a large amount of active oxygen is generated, which can produce a highly oxidizing environment for the oleic acid bacteria, which causes the bacteria to die from the surface and removes the acne on the skin. The red light-emitting diode used has a remarkable effect in skin care and health care when the wavelength of light emission is around 635 nm, and is called biologically active light. Red light can increase the activity of cells, promote the metabolism of cells, and cause the skin to secrete collagen and fibrous tissue to fill itself. Accelerate blood circulation, increase skin elasticity, improve skin chlorosis, and achieve anti-aging, anti-oxidation and repair effects, which can not be achieved by traditional skin care.

In addition, a green light-emitting diode having a wavelength of about 560 nm can be used. The color light provided by this wavelength has the effect of neutralizing and calming nerves, which can improve anxiety or depression. In addition, it can also regulate the function of skin glands, effectively clear lymphatics and edema, and improve oily skin and acne.

In addition, it has also been found that red light with a wavelength of 660-680 nm can increase the blood circulation of the skin surface, which is helpful for hair growth and hair quality improvement.

The photodynamic therapy device of the invention can convert light energy into intracellular energy, accelerate the cycle of cell growth process, and stimulate fiber cells to produce collagen. It can be used to repair aging skin, acne skin, acne skin, wrinkle skin, allergic symptoms, sunburn skin, and does not cause any harm or discomfort to the skin. Photodynamic power is the safest for acne and skin rejuvenation. And one of the most effective instruments. The scope of application is the treatment of skin beauty or repair, such as removing acne, eliminating or reducing acne scars, repairing sensitive skin, removing wrinkles (smoothing fine wrinkles), rejuvenating (melting, whitening, shrinking pores, Promote thickening of collagen layer), promote wound healing, anti-inflammatory and pain relief, and physiotherapy.

In addition to phototherapy alone, the photodynamic therapy device of the present invention can also apply some light-sensitive agent to the range of the skin to be irradiated to increase the therapeutic effect of light irradiation.

Obviously, many modifications and differences may be made to the invention in light of the above description. It is therefore to be understood that within the scope of the appended claims, the invention may be The above are only the preferred embodiments of the present invention, and are not intended to limit the scope of the claims of the present invention; all other equivalent changes or modifications which are not departing from the spirit of the present invention should be included in the following claims. Within the scope.

10‧‧‧Photodynamic therapy device body

20‧‧‧Rechargeable battery

30‧‧‧Lights

31‧‧‧Wire

40‧‧‧Circuit controller

50‧‧‧Lighting mat

60‧‧‧ headband

70‧‧‧Connector

80‧‧‧shims

The first figure is a perspective view of a photodynamic therapy device in accordance with a preferred embodiment of the present invention.

The second figure is a photodynamic therapy device attached to the preferred embodiment of the present invention. A three-dimensional diagram of the user's head.

The third figure is a perspective view of a photodynamic therapy device in another embodiment of the present invention.

The fourth figure is a perspective view of the photodynamic therapy device attached to the user's head in another embodiment of the present invention.

Figure 5 is a perspective view of a photodynamic therapy device in another embodiment of the present invention.

Figure 6 is a perspective view of the photodynamic therapy device attached to the user's head in another embodiment of the present invention.

10‧‧‧The main body of photodynamic therapy device

20‧‧‧Rechargeable battery

30‧‧‧Lights

31‧‧‧Wire

40‧‧‧Circuit controller

50‧‧‧Lighting mat

60‧‧‧ headband

70‧‧‧Connector

Claims (10)

A light therapy device comprising: a body having one or more illuminators, and circuitry for supplying current to the one or more illuminators; a shading device coupled to the body and in contact with the skin of the user, Blocking the light of the illuminant directly to the eye; a fixing device coupled to the body and in contact with the skin of the user to fix the body to the user's head; and a power source for providing the one or more illuminations Body power. The light therapy device of claim 1, wherein the power source comprises a power line, and the power line can be externally connected to another power source. The phototherapy device of claim 1, wherein the power source comprises a current control device for controlling current of the one or more illuminants. The phototherapy apparatus of claim 1, wherein the power source comprises a battery for supplying power required by the one or more illuminants. The phototherapy apparatus according to claim 4, wherein the battery is a rechargeable battery. The phototherapy apparatus according to claim 1, wherein the illuminant is a light-emitting diode. The phototherapy apparatus according to claim 1, wherein the fixing device is a headband. The phototherapy device of claim 7, wherein the headband is elastic. The light therapy device of claim 1, wherein the light shielding device is a soft material. The phototherapy device of claim 1, further comprising one or more spacers coupled to the body to maintain the one or more illuminants at a specific distance from the skin of the user.