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TW200800978A - Carbazole compound - Google Patents

Carbazole compound

Info

Publication number
TW200800978A
TW200800978A TW096108914A TW96108914A TW200800978A TW 200800978 A TW200800978 A TW 200800978A TW 096108914 A TW096108914 A TW 096108914A TW 96108914 A TW96108914 A TW 96108914A TW 200800978 A TW200800978 A TW 200800978A
Authority
TW
Taiwan
Prior art keywords
diseases
carbazole compound
salt
tract diseases
hydrogen atom
Prior art date
Application number
TW096108914A
Other languages
Chinese (zh)
Inventor
Takeshi Kuroda
Takahito Yamauchi
Tomoichi Shinohara
Kunio Oshima
Chiharu Kitajima
Hitoshi Nagao
Hironobu Ishiyama
Kazuhide Ohta
Masaaki Takano
Takumi Sumida
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of TW200800978A publication Critical patent/TW200800978A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The present invention provides a carbazole compound represented by formula (I) or a salt thereof, wherein A is a direct bond, a lower alkylene group, or a lower alkylidene group; X is an oxygen atom or a sulfur atom; R1 is a hydrogen atom, etc; R2 is a lower alkoxy group, etc; and R3 is a hydrogen atom, etc. The carbazole compound or salt thereof of the present invention induces the production of TFF, and thus is usable for the treatment and/or prevention of disorders such as alimentary tract diseases, oral diseases, upper respiratory tract diseases, respiratory tract diseases, eye diseases, cancers, and wounds.
TW096108914A 2006-03-23 2007-03-15 Carbazole compound TW200800978A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006080451 2006-03-23

Publications (1)

Publication Number Publication Date
TW200800978A true TW200800978A (en) 2008-01-01

Family

ID=38171158

Family Applications (1)

Application Number Title Priority Date Filing Date
TW096108914A TW200800978A (en) 2006-03-23 2007-03-15 Carbazole compound

Country Status (3)

Country Link
AR (1) AR059969A1 (en)
TW (1) TW200800978A (en)
WO (1) WO2007119600A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9199976B2 (en) 2010-06-01 2015-12-01 The University Of Queensland Haematopoietic-prostaglandin D2 synthase inhibitors
EP3321264A1 (en) * 2016-11-14 2018-05-16 Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft Selective inhibitors of genotoxic stress-induced ikk/nf-kb pathways
US11141402B2 (en) 2017-06-05 2021-10-12 National University Of Singapore Compounds useful in inhibiting human trefoil factor 3
CN107698579B (en) * 2017-11-23 2019-11-08 广东工业大学 A kind of carbazole derivative, its preparation method and its application in antitumor
WO2024079677A1 (en) * 2022-10-15 2024-04-18 Pillai Universal Llc Novel therapeutic molecule

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000511883A (en) * 1996-04-19 2000-09-12 ノボ ノルディスク アクティーゼルスカブ Modulators of molecules with phosphotyrosine recognition units
JP3812772B2 (en) * 1997-10-03 2006-08-23 富士写真フイルム株式会社 Photothermographic material
ES2288195T3 (en) * 2001-09-14 2008-01-01 Novo Nordisk A/S NEW LINKS FOR HISB10 ZN2 + SITES OF THE INSULIN HEXAMERO IN THE CONFIGURATION R.
JP2003264010A (en) * 2002-03-07 2003-09-19 Mitsubishi Paper Mills Ltd Photoelectric conversion element
EP1997855A3 (en) * 2002-07-29 2010-09-08 Mitsubishi Paper Mills Limited Organic dye, photoelectric transducing material, semiconductor electrode, and photoelectric transducing device
ES2297227T3 (en) * 2002-12-20 2008-05-01 Novo Nordisk A/S PHARMACEUTICAL COMPOSITIONS CONTAINING INSULIN AND LIGANDS OF INSULIN HEXAMERO.
JP2008505866A (en) * 2004-07-09 2008-02-28 ノボ　ノルディスク　アクティーゼルスカブ Pharmaceutical preparation containing insulin

Also Published As

Publication number Publication date
WO2007119600A1 (en) 2007-10-25
AR059969A1 (en) 2008-05-14
WO2007119600A9 (en) 2008-05-02

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