TW200416015A - Device for selectively generating hydrogen ions in an aqueous solution - Google Patents
Device for selectively generating hydrogen ions in an aqueous solution Download PDFInfo
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- TW200416015A TW200416015A TW092103574A TW92103574A TW200416015A TW 200416015 A TW200416015 A TW 200416015A TW 092103574 A TW092103574 A TW 092103574A TW 92103574 A TW92103574 A TW 92103574A TW 200416015 A TW200416015 A TW 200416015A
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- 239000001257 hydrogen Substances 0.000 title claims abstract description 26
- 229910052739 hydrogen Inorganic materials 0.000 title claims abstract description 26
- -1 hydrogen ions Chemical class 0.000 title claims abstract description 24
- 239000007864 aqueous solution Substances 0.000 title claims abstract description 5
- 230000005684 electric field Effects 0.000 claims abstract description 37
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 30
- 206010028980 Neoplasm Diseases 0.000 claims abstract description 11
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000000243 solution Substances 0.000 claims abstract description 8
- 239000004310 lactic acid Substances 0.000 claims abstract description 4
- 235000014655 lactic acid Nutrition 0.000 claims abstract description 4
- 150000002500 ions Chemical class 0.000 claims description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 5
- 150000007524 organic acids Chemical class 0.000 claims description 5
- 239000003792 electrolyte Substances 0.000 claims description 4
- 238000005259 measurement Methods 0.000 claims description 3
- 238000012544 monitoring process Methods 0.000 claims description 3
- 235000005985 organic acids Nutrition 0.000 claims description 3
- 230000017531 blood circulation Effects 0.000 claims description 2
- 239000007789 gas Substances 0.000 claims description 2
- 230000004089 microcirculation Effects 0.000 claims description 2
- 230000002079 cooperative effect Effects 0.000 claims 2
- 239000004615 ingredient Substances 0.000 claims 2
- 238000000018 DNA microarray Methods 0.000 claims 1
- 239000000835 fiber Substances 0.000 claims 1
- 230000004614 tumor growth Effects 0.000 claims 1
- 238000002604 ultrasonography Methods 0.000 claims 1
- 239000013078 crystal Substances 0.000 abstract description 5
- 239000007788 liquid Substances 0.000 abstract description 4
- 238000009825 accumulation Methods 0.000 abstract description 2
- 230000004087 circulation Effects 0.000 abstract description 2
- 239000004065 semiconductor Substances 0.000 abstract description 2
- 238000001467 acupuncture Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 238000007669 thermal treatment Methods 0.000 abstract 1
- 238000005868 electrolysis reaction Methods 0.000 description 11
- 230000000694 effects Effects 0.000 description 10
- 230000008859 change Effects 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 210000005036 nerve Anatomy 0.000 description 4
- GPRLSGONYQIRFK-UHFFFAOYSA-N hydron Chemical class [H+] GPRLSGONYQIRFK-UHFFFAOYSA-N 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 230000002232 neuromuscular Effects 0.000 description 3
- 230000000638 stimulation Effects 0.000 description 3
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 230000004118 muscle contraction Effects 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000001052 transient effect Effects 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010020843 Hyperthermia Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010060820 Joint injury Diseases 0.000 description 1
- 206010050031 Muscle strain Diseases 0.000 description 1
- 208000037063 Thinness Diseases 0.000 description 1
- 230000036982 action potential Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 230000002964 excitative effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000036031 hyperthermia Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 210000001503 joint Anatomy 0.000 description 1
- 230000009191 jumping Effects 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 210000004088 microvessel Anatomy 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000013021 overheating Methods 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 229910001414 potassium ion Inorganic materials 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229910001415 sodium ion Inorganic materials 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring pH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/251—Means for maintaining electrode contact with the body
- A61B5/257—Means for maintaining electrode contact with the body using adhesive means, e.g. adhesive pads or tapes
- A61B5/259—Means for maintaining electrode contact with the body using adhesive means, e.g. adhesive pads or tapes using conductive adhesive means, e.g. gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Radiology & Medical Imaging (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
Description
在很多水分子時, 以百計之不同結晶 分子之次晶體 2UU416015 A7 五、發明説明When there are many water molecules, there are hundreds of different crystals. Secondary crystals of molecules 2UU416015 A7 V. Description of the invention
]c為所有生物體之主要成分,故生物體皆可視為水溶 液之容器。水分子鱗常鮮之分子明,但因為有極性, 又有結晶的傾向,故凝結為冰時,有數 。而液體水分子亦由氫鍵結成5-20個 在W液中之氫離子,可沿著氫鍵之方向作跳躍式之 移動’ _錄子之移雜柄有離子巾最大者。利用此 氫離子在水溶財之紐,可以雜低輕來使其移動。 但右為&加產生氫離子之雜,以達成所需之效果,如量 測pH、或藉此移動所產生之電流加熱’則希望所用之電 壓越大越好。但如電壓太大,他離子被移動,便沒有 選擇性的移動氫離子之特殊效果。故其電壓之極限,為不 誘發水分子產生電解之電壓。但如所加電壓雖不致引起水 的電解’僅維持-定之直流電,仍可引發短暫之離子(如 鈉、氣、鉀等)移動電流。為避免此短暫之離子電流,可 以用極快速之電壓變化。此變化如快於一毫秒(ims),則 氫離子先被移動,產生瞬間電流,而其他短暫離子電流, 一來因為電場已因氫離子移動而變小,二來因為各離子四 周有很多吸附之水分子(4-11個),所以質量很大,阻力 本紙張尺度適财11國家辟(CNS ) ( 21()X297公餐) —~ ----一] c is the main component of all living organisms, so living organisms can be regarded as containers for aqueous solutions. Water molecules are often fresh and bright, but because they are polar and tend to crystallize, there are several when they condense into ice. The liquid water molecules are also formed by hydrogen bonding into 5-20 hydrogen ions in the W liquid, which can be moved in a jumping manner along the direction of the hydrogen bonding. Using this hydrogen ion to dissolve wealth in water, you can move it by mixing light and light. But on the right is the & addition of hydrogen ions, in order to achieve the desired effect, such as measuring pH, or heating by the current generated by this movement ', I hope that the greater the voltage used, the better. However, if the voltage is too high, other ions will be moved without the special effect of selectively moving hydrogen ions. Therefore, its voltage limit is a voltage that does not induce electrolysis of water molecules. However, if the applied voltage does not cause the electrolysis of water to maintain only a constant DC current, it can still cause a short-term moving current of ions (such as sodium, gas, potassium, etc.). To avoid this transient ion current, extremely rapid voltage changes can be used. If this change is faster than one millisecond (ims), the hydrogen ions are first moved to generate an instantaneous current, while other transient ion currents are reduced because the electric field has been reduced due to the movement of hydrogen ions, and because there is a lot of adsorption around each ion. Water molecules (4-11), so the quality is very large, resistance to this paper is suitable for the 11 countries (CNS) (21 () X297 public meals) — ~ ---- 1
訂 線 濟 部 智 慧 財 產 局 消 費 合 製 200416015 經 濟 部 智 .¾ 財 產 局 i 三 消 货 合 h 印 製 A7 Β7 五、發明説明(么) (viscosity)更大,故其產生之電流遠小於氫離子。因此, 就如同電洞在半導體中產生電流一般,氫離子在水之次晶 體中跳躍,亦可產生電流。 當電壓越來越大時,水可能電解,神經與肌肉也可能 興奮。在生物體中,當電場產生的電流小於一毫秒時,可 避免神經及肌肉受電刺激而產生神經衝動或肌肉收縮,同 時產生大量的鉀鈉離子穿越細胞膜之移動,而混亂了本儀 之選擇性功能,故本儀器之電場必須在一毫秒之内變 換,並由此快速變換特性來達成選擇性產生氫離子移動之 目的。而當電源為交流時,水之電解電麼、神經肌肉之興 奮電壓’又可隨交流電之頻率而逐漸提高。故以—水電解 偵測器以監視水之電解,並同時監視神經與肌肉之動作電 位,至為重要。因此用來防止因水電解而產生之副作用, 或降低測量之準確度。此細器有許多實施方式,此處僅 提出兩個簡單的方法。一為電極固定後,直接偵測所提供 之電流’如忽然變成不穩,就可能是已發生水電解或神經 衝動之信號,則需將電壓降低,或將頻率加高。另一偵剛 法為用超音波方式,如有電解或肌肉收縮,則透過超音波 反射喊,同時有某程度訊號變異,我們便可知曉。但在Set the line Consumption system of the Ministry of Economic Affairs and Intellectual Property, 200416015 Ministry of Economic Affairs. ¾ The property bureau, the third consumer goods, and the printed A7 B7 V. The invention description (?) (Viscosity) is larger, so the current it generates is far less than hydrogen ions . Therefore, just as holes generate current in semiconductors, hydrogen ions jump in the sub-crystal of water and can also generate current. As the voltage increases, water may electrolyze, and nerves and muscles may be excited. In organisms, when the electric current generated by the electric field is less than one millisecond, it can avoid nerve impulses or muscle contractions caused by electrical stimulation. At the same time, a large amount of potassium and sodium ions are moved across the cell membrane, which confuses the instrument's selectivity. Function, the electric field of the instrument must be changed within one millisecond, and the characteristics of fast change can be achieved to achieve the purpose of selectively generating hydrogen ion movement. And when the power source is AC, the electrolysis of water and the voltage of neuromuscular stimulation 'can gradually increase with the frequency of AC. Therefore, it is very important to use the water electrolysis detector to monitor the electrolysis of water and simultaneously monitor the action potentials of nerves and muscles. Therefore, it is used to prevent the side effects caused by water electrolysis or reduce the accuracy of the measurement. There are many implementations of this thinner, and here only two simple methods are proposed. Once the electrode is fixed, the current provided by direct detection is suddenly unstable. It may be a signal that water electrolysis or nerve impulses have occurred. You need to reduce the voltage or increase the frequency. Another method of detection is to use the ultrasonic method. If there is electrolysis or muscle contraction, then shout through the ultrasonic reflection, and there is a certain degree of signal variation, we can know. But in
----------裝------1Τ------線 (請先閲讀背面之注意事項再填寫本頁J 本紙狀度 t關家標準(CNS ) 297公^丁 200416015 A7 五、發明説明(3 ) ^-- 了解特定電極、電壓、頻率與水電解與神經肌肉興奮電位 之關係後,可直接設定電壓及頻率,而不使用監視系統。 在交流電壓中,以正負雙向方波,其電壓在不電解水也不 產生神經肌肉興奮的狀況下,變化最大,而且其中高頻之 4波最夕,故為選擇性移動氫離子之較佳波形。此時電流 可反應氫離子之密度,PH越低電流越大。在生理上,可 以此私流作為pH之量測工具。如欲定點量測時,可以用 極小電極刺入標的部位(如圖一)因為此時電流的產生, 會集中於極小電極之表面,故由電流之定量,計算極小電 極附近之pH值。 錢療目的上,射祕_之早期細、定位與高 熱治療,因為許多腫瘤,尤其是早期之腫瘤,多利用無氧 代謝葡萄糖(gly⑺lysis) ’因為堆積乳酸(ia敝)而使局 部_降低;由此儀器產生之選擇性氫離子⑽,赴 f 紋、,由此產生之電流可砂财異常雜標的之存在, | 亚可進而由數個電極之巧妙安排為之定位。如確定是腫 I瘤’又可此異常電流將標的選紐加熱。由此電流產 !生熱二則加熱之部位可集中於腫瘤之位置,因而達到自動 I 選擇定位之效果,像巡弋飛彈一樣。 本紙 K度1~~~._____ 奸本-- (請先閱讀背面之注意事項再填寫本頁) 、1Τ 1- - I g_*I · ί線 齊 •r % 忖 i 本纸乐尺度適用中囤國家樣準 200416015 五 '發明説明(+ 取間早之定位為以小電極作為電場集中點放在伊的 將各電極偶中之—崎在此小電極,酬處樓必 為集中點。但此時需注意因電堡太大產生水之電解。又為 防止過熱,可將熱感電極放於此處,以回饋信號作為溫度 之控制指標。如為數個電極偶協同運作,沒有定位小電極, 則可先由各個電極偶之間组織之導電性,估算各電極偶之 電流路徑。務使其通過標的,如各_極偶產生之電場皆 通過仏的’則數個放在不同位置之電極偶一同操作,則電 場必皆通過標的,則產生電流之效應必能相加。此時亦可 用時間分散之方式操作’則各電極偶錢秒之内依時序產 生的電場,而產生電流。因各電極偶產生之電場皆通過標 的’故僅標的同時受到數個電極偶產生之電流加熱,其他 對電極偶分時工作,則其他部分電 *為I的之1/N。更因電場為向量,亦可以電場在同位置 相加之方式運作’當各電極偶在標的產生之電場如能同步 又同向,則相加之效果最大,產生的電流最強。而各組電 極之間其他位置之電場,則無此相加電場,故電流較小。 戶對電極偶皆同日私作,則其他部分所受之電流為 心的之1/N2。而標的本身阳較低,氫離子電流本易產生, (CNS ) A4規格(21 〇 X 297公慶---------- install ------ 1T ------ line (please read the precautions on the back before filling in this page. ^ D 200416015 A7 V. Description of the invention (3) ^-After understanding the relationship between specific electrodes, voltage, frequency, water electrolysis and neuromuscular excitatory potential, you can directly set the voltage and frequency without using a monitoring system. In AC voltage With positive and negative two-way square waves, its voltage changes the most under the condition that it does not electrolyze water and does not produce neuromuscular excitement, and the high frequency of 4 waves is the easiest, so it is the better waveform for selective movement of hydrogen ions. At this time The current can reflect the density of hydrogen ions. The lower the pH, the larger the current. Physiologically, this private flow can be used as a measuring tool for pH. For fixed-point measurement, you can pierce the target site with a very small electrode (see Figure 1). Because the current generation at this time will be concentrated on the surface of the extremely small electrode, the pH value near the extremely small electrode is calculated from the quantification of the current. For the purpose of money therapy, the early thinness, positioning and hyperthermia treatment of the esophagus, because many tumors, Especially for early tumors, use anaerobic Glucose (gly⑺lysis) 'Reduction of local _ due to accumulation of lactic acid (ia_); Selective hydrogen ions produced by this instrument go to f lines, and the resulting current can be the existence of abnormal impurities, | Asia It can be further positioned by the clever arrangement of several electrodes. If it is determined that the tumor is a tumor, then the abnormal current can be used to heat the target button. From this, the current is generated! The heat can be concentrated on the location of the tumor. Therefore, the effect of automatic I selection positioning is achieved, just like a patrol missile. This paper K degree 1 ~~~. _____ Rapbook-(Please read the precautions on the back before filling this page), 1T 1--I g_ * I · ί LINE Qi • r% 忖 i The paper music scale is applicable to the national standard of the country 200416015 Five 'invention description (+ Toma early positioning is to use a small electrode as the electric field concentration point in Yi's will be in each electrode pair-Qi In this small electrode, the pay office building must be the concentration point. But at this time, it is necessary to pay attention to the electrolysis of water due to the large electric fort. To prevent overheating, you can place the thermal sensor here, and use the feedback signal as the temperature control. Indicators, such as coordinated operation of several electrode pairs Without positioning the small electrode, you can first estimate the current path of each electrode pair based on the conductivity of the tissue between each electrode pair. Make sure to pass the target, such as the electric field generated by each _pole pair through 则When the electrode pairs placed at different positions are operated together, the electric field must pass the target, and the effect of generating current must be added. At this time, it can also be operated in a time-dispersed manner. The current is generated. Because the electric field generated by each electrode pair passes the target ', so only the target is heated by the current generated by several electrode pairs at the same time, and the other pairs of electrodes work when divided, the other part of the electricity * is 1 / N of I Moreover, because the electric field is a vector, it can also be operated by adding the electric fields at the same location. 'When the electric fields generated by the electrode pairs at the target can be synchronized and in the same direction, the effect of the addition is the largest and the current generated is the strongest. The electric field at other positions between the electrodes of each group does not have this added electric field, so the current is small. Household-to-electrode couples are all made on the same day, so the current received by other parts is 1 / N2 of the heart. The target itself is relatively low, and the hydrogen ion current is easy to produce. (CNS) A4 specification (21 × 297
200416015 五、發明説明(A ) 就更能產生定位加熱之功效,在使用時,可先以小電場產 生小電流作為測試,先為各電極偶定位。待測試有效後’ 再施用較大電場以達加熱效果。 如已確知標的位置亦可將兩種電極偶之安排方式合 ’以其中之-部份電極偶為較遠距離之電極偶,同時亦 有部份為較小電極偶在標的,則可同時取得兩種定位之優 ”,、占也可同蚪有溫度之回饋。加熱之標的可為腫瘤等循環 不良之所在,包含器官,骨關節,酸痛之肌肉,甚至脂肪 層,可有治療腫瘤,器官衰弱,關節受傷,肌肉拉傷,以 及減少脂肪,減肥等用途。 這種移動氫離子之動作,因可改變水之次晶體結構, 故亦可大崎低水溶液之黏雜。黏雜在非常小之管徑 中可能變得很大。本發明可利用外加電場,來達联低黏 滯性之效果,這種用途在生物微晶片的設計上特別有用。 亦可在生物體之微循環處如小動脈或微血管來改善血液循 壞。 磁%之受化亦可產生電場’由可知,如 能在標的物產生磁場,再讓磁場快速變換則可產生電場, 此電場環繞原來之磁力線。如磁場集中在標的,則由此產 ----裝-- (請先閲讀背面之注意事項再填寫本頁) 訂 空齊.^rs^i^g: rl 肖^^乍注^^ --線--- 本紙張尺度適用中國國家標準(CNs ) μ規格(210X 297公釐) 200416015 五、發明説明(6) 生之電場亦麵近’财由此產 生王〈蛋%推動電流。只要 磁場之變化快速,則由此產 之H電流仍為電流之主要 組成。由設計之導電線圈放 e 、, 牡!遐四周,通電便產生磁 場’並安棑使磁場在標的為最 取强貝丨由此線圈之改變就能 產生交流電場,達到產生電場之目的,此電場也可以像上 述由電極產生之電場-樣由數她成,而以分時工作方 式’或同時加成之工作方式,來遽到對標的特定位置,產 生電流之效果。 在電極及與身體接觸處,經常使用膠狀液,在此儀器 中’為了使電場容易通過這個界面,此界面一定要有電解 質,如果此電解質之pH很低,則有报多氫離子可導電, 因此可降低電阻,以減少電極上產生高電壓及水之電解, 亦可減少電極處發熱,而含水之電解質比μ大,可減緩 溫度之上昇。故以低阳之溶液作為電極與身體界面之介 質為很理想之選擇,而為了與身體接觸之生物相容性,則 有機酸為較佳之選擇,例如醋酸,乳酸,……等。 這種膠狀液可單獨使用,可在任何心電圖,腦波,机 電圖等等生理電信號,以及各種電刺激用等等之電極,其 ^ 與身體1可包含這齡質,因由低pH之溶液組 本纸法—適^ 200416015 A7 B7 五、發明説明(Y ) 成,故可降低電阻,尤其是高頻之阻抗,而大大增加效率。 圖一;一種電極偶之組合,用來移動02電極附近之氫離子,01爲大 面積之電極,02爲小面積之電極。 (a)下視圖 (b)由中央切開之切面圖 圖二;一種數個電極偶之組合,03爲一組,04爲一組,05爲一組, 用來移動電極組之間之氫離子,尤其是各組電極偶電場之交會 點,本圖是在人體施用之示意圖。 扣衣 訂 線 (請先閱讀背面之注意事項再填寫本頁) 經濟部智慧財產局資工消費合作钍印¾ 本紙伕尺度適用中國國家標隼(CNS〉A4規格(210'Χ Z97公釐)200416015 V. Description of the invention (A) can produce the effect of positioning heating even more. When using, you can first use a small electric field to generate a small current as a test, and first position each electrode pair. After the test is effective, a larger electric field is applied to achieve the heating effect. If the position of the target is known, the arrangement of the two types of electrode pairs can also be combined. 'One of them-some electrode pairs are long-distance electrode pairs, and some of the smaller electrode pairs are at the same time. "The two types of positioning are excellent", and can also be accompanied by temperature feedback. The target of heating can be tumors and other poor circulation, including organs, bones and joints, sore muscles, and even the fatty layer, which can be used to treat tumors and organs. Weakness, joint injury, muscle strain, fat reduction, weight loss, etc. This movement of hydrogen ions can change the secondary crystal structure of water, so it can also stick to Osaki low-water solution. Sticks are very small The pipe diameter may become very large. The present invention can use an external electric field to achieve the effect of low viscosity. This application is particularly useful in the design of biological microchips. It can also be as small as the microcirculation of biological bodies. Arteries or microvessels can improve blood circulation. The magnetic% can also generate an electric field. It can be known that if a magnetic field can be generated in the object, and then the magnetic field can be quickly transformed, an electric field can be generated. This electric field surrounds the original Here comes the magnetic field line. If the magnetic field is concentrated in the target, it will be produced from this ----------- (please read the precautions on the back before filling in this page). Complete the order. ^ Rs ^ i ^ g: rl ^^^^ Note ^^-Line --- This paper size is in accordance with Chinese National Standards (CNs) μ specifications (210X 297 mm) 200416015 V. Description of the invention (6) The electric field of health is also close to the 'cause of the wealth produced by the king <eg% Promote the current. As long as the magnetic field changes rapidly, the H current produced by it is still the main component of the current. By designing the conductive coil to put e ,, !! 四周 Around, the power will generate a magnetic field 'and install the magnetic field at the target as The best choice is the change of the coil, which can generate an alternating-current electric field to achieve the purpose of generating an electric field. This electric field can also be counted as the electric field generated by the electrode described above, and work in a time-sharing manner. The working method is to reach the specific position of the target and produce the effect of current. In the electrode and the contact with the body, a gel liquid is often used. In this instrument, in order to make the electric field easily pass through this interface, this interface must have Electrolyte, if the pH of this electrolyte If it is low, it is reported that multiple hydrogen ions can conduct electricity, so the resistance can be reduced to reduce the high voltage and electrolysis of water on the electrode, and the heat generated at the electrode can be reduced, and the electrolyte ratio containing water is larger, which can slow the temperature rise. It is ideal to use a low-yang solution as the medium between the electrode and the body, and for biocompatibility with the body, organic acids are better choices, such as acetic acid, lactic acid, etc. The fluid can be used alone, and can be used on any electrocardiogram, electroencephalogram, electromechanical and other physiological electrical signals, as well as electrodes for various electrical stimulation, etc., and its body 1 can contain this age, because of the low pH solution composition Paper method—suitable 200416015 A7 B7 V. Description of the invention (Y), it can reduce the resistance, especially the impedance at high frequencies, and greatly increase the efficiency. Figure 1: A combination of electrode pairs is used to move hydrogen ions near the 02 electrode, 01 is a large area electrode, and 02 is a small area electrode. (a) Bottom view (b) Sectional view cut from the center Figure 2; A combination of several electrode pairs, 03 is a group, 04 is a group, 05 is a group, used to move the hydrogen ions between the electrode groups , Especially the intersection of the electric field of each group of electrode pairs, this figure is a schematic diagram of application on the human body. Buttons and Threads (Please read the precautions on the back before filling out this page) Printed by the Intellectual Property Bureau of the Ministry of Economic Affairs, Industrial and Consumer Cooperative Seals ¾ This paper is in accordance with Chinese national standards (CNS> A4 (210 '× Z97 mm)
Claims (1)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW092103574A TW200416015A (en) | 2003-02-17 | 2003-02-17 | Device for selectively generating hydrogen ions in an aqueous solution |
| US10/780,155 US20040159541A1 (en) | 2003-02-17 | 2004-02-17 | Apparatus for selectively moving hydrogen ions in aqueous solutions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW092103574A TW200416015A (en) | 2003-02-17 | 2003-02-17 | Device for selectively generating hydrogen ions in an aqueous solution |
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| Publication Number | Publication Date |
|---|---|
| TW200416015A true TW200416015A (en) | 2004-09-01 |
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ID=32847881
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW092103574A TW200416015A (en) | 2003-02-17 | 2003-02-17 | Device for selectively generating hydrogen ions in an aqueous solution |
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| Country | Link |
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| US (1) | US20040159541A1 (en) |
| TW (1) | TW200416015A (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2011254122A (en) * | 2009-03-23 | 2011-12-15 | Nec Corp | Circuit, control system, control method, and program |
| CN116908244B (en) * | 2023-09-13 | 2023-12-22 | 四川省林业和草原调查规划院 | Sampling device for forestry ecological protection |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DE2105998C3 (en) * | 1971-02-09 | 1979-02-15 | Furnier- Und Sperrholzwerk J.F. Werz Jr. Kg Werzalit-Pressholzwerk, 7141 Oberstenfeld | Device for the production of molded parts from a mixture of lignocellulose-containing fibers and a thermosetting binder |
| JPS5933361Y2 (en) * | 1980-03-14 | 1984-09-18 | 日東電工株式会社 | electrode pad |
| US4662952A (en) * | 1984-06-29 | 1987-05-05 | Massachusetts Institute Of Technology | Non-hygroscopic welding flux binders |
| WO1989006555A1 (en) * | 1988-01-21 | 1989-07-27 | Massachusetts Institute Of Technology | Transport of molecules across tissue using electroporation |
| US5143071A (en) * | 1989-03-30 | 1992-09-01 | Nepera, Inc. | Non-stringy adhesive hydrophilic gels |
| US5047007A (en) * | 1989-12-22 | 1991-09-10 | Medtronic, Inc. | Method and apparatus for pulsed iontophoretic drug delivery |
| US5499967A (en) * | 1992-02-27 | 1996-03-19 | Societe Anonyme Dite: Laboratoires D'hygiene Societe Anonyme Dite: Et De Dietetique (L.H.D.) | Transdermal drug delivery device with waveshape generator |
| EP0643981B1 (en) * | 1993-09-22 | 2002-01-09 | Hisamitsu Pharmaceutical Co., Inc. | A matrix for iontophoreses |
| US5673721A (en) * | 1993-10-12 | 1997-10-07 | Alcocer; Charles F. | Electromagnetic fluid conditioning apparatus and method |
| US6029090A (en) * | 1997-01-27 | 2000-02-22 | Herbst; Ewa | Multi-functional electrical stimulation system |
| US6018679A (en) * | 1997-01-29 | 2000-01-25 | Novartis Finance Corp. | Iontophoretic transdermal delivery and control of adverse side-effects |
| US6117660A (en) * | 1997-06-10 | 2000-09-12 | Cytopulse Sciences, Inc. | Method and apparatus for treating materials with electrical fields having varying orientations |
| US6043066A (en) * | 1997-09-04 | 2000-03-28 | Mangano; Joseph A. | Cell separation using electric fields |
| DE19823047C1 (en) * | 1998-05-22 | 1999-08-26 | Fuhr | Electro-manipulation of cells for permeation and fusion reduces stress on cells due to pH fluctuations |
| WO2000071024A1 (en) * | 1999-05-25 | 2000-11-30 | Medicotest A/S | A skin electrode |
| EP1228158B1 (en) * | 1999-08-24 | 2008-07-30 | Henkel AG & Co. KGaA | Bonding by adhesives containing nanoparticles |
| US6561968B1 (en) * | 1999-08-31 | 2003-05-13 | Biofields Aps | Method and an apparatus for stimulating/ modulating biochemical processes using pulsed electromagnetic fields |
| US7599745B2 (en) * | 2000-02-17 | 2009-10-06 | Standen Ltd | Treating a tumor or the like with an electric field |
| US7089054B2 (en) * | 2002-10-02 | 2006-08-08 | Standen Ltd. | Apparatus and method for treating a tumor or the like |
| US20020147424A1 (en) * | 2000-12-26 | 2002-10-10 | Alvin Ostrow | Transdermal magnetic drug delivery system and method |
| US6877556B2 (en) * | 2001-10-26 | 2005-04-12 | Electro-Petroleum, Inc. | Electrochemical process for effecting redox-enhanced oil recovery |
| US20030093028A1 (en) * | 2001-11-09 | 2003-05-15 | Michael Spiegel | Appararus and method for magnetic induction of therapeutic electric fields |
| US7288062B2 (en) * | 2001-11-09 | 2007-10-30 | Michael Spiegel | Apparatus for creating therapeutic charge transfer in tissue |
| US6745078B1 (en) * | 2002-04-24 | 2004-06-01 | Kelly W. Buchner | Procedure and machine for electro-inducing/stimulating deep-layered muscle contractions using a biphasic faradic pulse sequence |
| US6830550B2 (en) * | 2002-06-25 | 2004-12-14 | James Lee Hedgecock | Stair step voltage actuated measurement method and apparatus |
-
2003
- 2003-02-17 TW TW092103574A patent/TW200416015A/en unknown
-
2004
- 2004-02-17 US US10/780,155 patent/US20040159541A1/en not_active Abandoned
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| US20040159541A1 (en) | 2004-08-19 |
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