TR2022007546A2 - POMAD CREAM - Google Patents
POMAD CREAMInfo
- Publication number
- TR2022007546A2 TR2022007546A2 TR2022/007546 TR2022007546A2 TR 2022007546 A2 TR2022007546 A2 TR 2022007546A2 TR 2022/007546 TR2022/007546 TR 2022/007546 TR 2022007546 A2 TR2022007546 A2 TR 2022007546A2
- Authority
- TR
- Turkey
- Prior art keywords
- skin
- weight
- cream
- feature
- calendula
- Prior art date
Links
- 239000006071 cream Substances 0.000 title claims abstract description 61
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 35
- 240000001432 Calendula officinalis Species 0.000 claims description 20
- AJBZENLMTKDAEK-UHFFFAOYSA-N 3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-4,9-diol Chemical compound CC12CCC(O)C(C)(C)C1CCC(C1(C)CC3O)(C)C2CCC1C1C3(C)CCC1C(=C)C AJBZENLMTKDAEK-UHFFFAOYSA-N 0.000 claims description 19
- 235000003880 Calendula Nutrition 0.000 claims description 19
- 239000003921 oil Substances 0.000 claims description 19
- 239000000284 extract Substances 0.000 claims description 17
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 15
- 244000163122 Curcuma domestica Species 0.000 claims description 14
- 235000003373 curcuma longa Nutrition 0.000 claims description 14
- 239000000341 volatile oil Substances 0.000 claims description 13
- QCYLIQBVLZBPNK-UHFFFAOYSA-N asiaticoside A Natural products O1C(C(=O)C(C)C)=CC(C)C(C2(C(OC(C)=O)CC34C5)C)C1CC2(C)C3CCC(C1(C)C)C45CCC1OC1OCC(O)C(O)C1O QCYLIQBVLZBPNK-UHFFFAOYSA-N 0.000 claims description 12
- BNMGUJRJUUDLHW-HCZMHFOYSA-N Madecassoside Chemical compound O([C@@H]1[C@@H](CO)O[C@H]([C@@H]([C@H]1O)O)OC[C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)OC(=O)[C@]12CC[C@H]([C@@H]([C@H]1C=1[C@@]([C@@]3(C[C@@H](O)[C@H]4[C@](C)(CO)[C@@H](O)[C@H](O)C[C@]4(C)[C@H]3CC=1)C)(C)CC2)C)C)[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O BNMGUJRJUUDLHW-HCZMHFOYSA-N 0.000 claims description 11
- BNMGUJRJUUDLHW-HLUHVYOBSA-N Madecassoside Natural products C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5[C@H](O)C[C@@]34C)[C@@H]2[C@H]1C)C(=O)O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO)[C@@H](O[C@@H]8O[C@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O)[C@H]6O BNMGUJRJUUDLHW-HLUHVYOBSA-N 0.000 claims description 11
- 229940090813 madecassoside Drugs 0.000 claims description 11
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- 244000131522 Citrus pyriformis Species 0.000 claims description 10
- NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 claims description 10
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- 244000042664 Matricaria chamomilla Species 0.000 claims description 9
- 235000007232 Matricaria chamomilla Nutrition 0.000 claims description 9
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- 235000007866 Chamaemelum nobile Nutrition 0.000 claims description 8
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 8
- 239000000419 plant extract Substances 0.000 claims description 8
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- 241000208690 Hamamelis Species 0.000 claims description 7
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- 235000013976 turmeric Nutrition 0.000 claims description 7
- 229940118846 witch hazel Drugs 0.000 claims description 7
- AALXZHPCKJILAZ-UHFFFAOYSA-N (4-propan-2-ylphenyl)methyl 2-hydroxybenzoate Chemical compound C1=CC(C(C)C)=CC=C1COC(=O)C1=CC=CC=C1O AALXZHPCKJILAZ-UHFFFAOYSA-N 0.000 claims description 6
- PJTNSWOJMXNNFG-UHFFFAOYSA-N 8-methylnonyl 2-hydroxybenzoate Chemical compound CC(C)CCCCCCCOC(=O)C1=CC=CC=C1O PJTNSWOJMXNNFG-UHFFFAOYSA-N 0.000 claims description 6
- ZYEMGPIYFIJGTP-UHFFFAOYSA-N O-methyleugenol Chemical compound COC1=CC=C(CC=C)C=C1OC ZYEMGPIYFIJGTP-UHFFFAOYSA-N 0.000 claims description 6
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 6
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- JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical compound OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 claims description 5
- 229940043375 1,5-pentanediol Drugs 0.000 claims description 5
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims description 5
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- SZYSLWCAWVWFLT-UTGHZIEOSA-N [(2s,3s,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)-2-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-yl]methyl octadecanoate Chemical compound O([C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@]1(COC(=O)CCCCCCCCCCCCCCCCC)O[C@H](CO)[C@@H](O)[C@@H]1O SZYSLWCAWVWFLT-UTGHZIEOSA-N 0.000 claims description 5
- 229940081733 cetearyl alcohol Drugs 0.000 claims description 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 5
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- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 5
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- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 5
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 4
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 4
- 239000005711 Benzoic acid Substances 0.000 claims description 4
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 4
- 235000010469 Glycine max Nutrition 0.000 claims description 4
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- 241001227551 Lavandula x intermedia Species 0.000 claims description 4
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Abstract
Buluş, çeşitli çevresel faktörlerle tahriş olan cildin iyileştirilmesi ve onarılmasını destekleyici etkiye sahip pomad yapılı bir krem ve bunun üretim yöntemi ile ilgilidir. Buluş konusu krem doğal ve organik bileşenler içermektedir.The invention relates to a pomade cream that has a supportive effect on the healing and repair of skin irritated by various environmental factors and its production method. The cream of the invention contains natural and organic ingredients.
Description
TARIFNAME POMAD KREM TEKNIK ALAN Bulus, çesitli çevresel faktörlerle tahris olan cildin iyilestirilmesi ve onarilmasini destekleyici etkiye sahip pomad yapili bir krem ve bunun üretim yöntemi ile ilgilidir. Bulus konusu krem dogal ve organik bilesenler içermektedir. TEKNIGIN BILINEN DURUMU Kozmetik ürünler saç, cilt, yüz, tirnak vb. gibi çesitli bölgelerde kullanima uygun temizleyici, koku verici, görünümü degistirici, koruyucu ve bazen içerige göre iyilestirici ve onarici etkileri saglayan preparatlar olarak bilinmektedir. Kozmetik ürünlerin içerigindeki bazi kimyasal maddeler insan sagligi açisindan çesitli olumsuz etkilere yol açabilmekte ve kullanicilar gün içerisinde farkinda olmadan kimyasallarin olumsuz etkilerine maruz kalabilmektedir. Kozmetik ürünlerin içerisinde yer alan bu kimyasallar sadece kullaniciya degil çevreye (su, toprak, hava) ve dolasiyla dogada yasayan tüm canlilara da zarar vermektedir. Son zamanlarda faydalarindan çok yan etkilerin olmasi sebebiyle tüketicilerin sentetik ürünlere olan inanci azalmis dolayisiyla dogal yapida bitkisel içerikli ürünlere yönelim artmistir. Temiz içerik olmasi, dogal olmasi ve kullanilan ürünün birden çok etkiyi bir arada sunabilmesi ürünün tercih edilme kriterlerini belirlemektedir. Bu ihtiyaçlari karsilamak adina firmalar da ürün reklamlarinda veya ambalajlari üzerinde ürünün içeriklerine yönelik bilgileri ön plana çikarmaya baslamislardir (Paraben, sles içermez, dogal içerik, bitkisel vb.). Yüzyillardan beri bitkilerin tamaminin veya bir kisminin çesitli cilt rahatsizliklarinda kullanildigi bilinmektedir. Bununla birlikte bilimsel çalismalara, klinik deneylere ve farmakolojik testlerin incelenmesine dayanarak bitkilerin çok büyük miktarlarda ve kompleks yapilarda cildi iyilestiren ve onaran fitokimyasallara sahip oldugu görülmektedir. Organik maddelerin canli organizmalarda üretilen enzimler tarafindan aerobik veya anaerobik olarak parçalanmasini içeren bir sistemde çözülme ve bozunma egiliminde olan biyobozunur ürünler dogaya zarar vermeden çözünebilmektedir. Bu yüzden kozmetik ürünlerde de içerikte kullanilan malzemelerin çevre dostu, geri-dönüstürülebilir veya biyolojik olarak ayristirilabilen özelliklerde olmasi hem üreticiler hem de tüketiciler tarafindan bir tercih sebebi olmaktadir. Bir biyobozunur kozmetik ürünü, mikroplastikleri, silikon çesitlerini ve farkli adlarla karsimiza çikan "-kon , -konol", "-siloksan" ile biten malzemeleri içermemelidir. Cilt bakiminda mucizeler yaratan Centella Asiati'ca bitkisi en yaygin olarak Gotu Kola (Kaplan Otu) adiyla anilir. Güney Kore kozmetik ürünlerinin içeriginde vazgeçilmez bir yere sahip olan bu bitki, tedavi edici özelligi nedeniyle saglik sektöründe de kullanilir. Centella Asiati'ca bitkisinin cilt üzerinde anti-aging özelligi ile yaslanma sonucu ortaya çikan kirisiklik, sarkma gibi sorunlari önleme, sivilce ve yaralarin iyilesmesinin ardindan olusan izlerin kaybolmasini saglama, yaralar üzerinde iyilestirici bir etki gösterme, hassas yapida olan ciltler için uygun yapili olmasi, cildi sakinlestirmesi ve cilt bariyerini onarmasi gibi faydalari vardir. Centella Asiati'ca bitkisinin içinde madecassoside, asiatikosit, asiatik asit ve madekasik asit aktif bilesenleri bulunur. Madecassoside, Centella Asiati'casnin oldukça saflastirilmis bir glikosile triterpenidir. Yaslanma karsiti, hassas ciltler, çok kuru ciltler ve olgun cilt uygulamalarinda kullanim için uygun bir aktif bilesendir. Madecassoside, kolaj en ekspresyonunu aktive eder, keratinositlerin hiperproliferasyonunun normallesmesini, küresel anti-inflamatuar özelliklerin ve asiri deskuamasyon üzerinde görünür bir etki Cilt üzerine lokal uygulama için kullanilan kozmetik ürünler krem, pomad (merhem), jel, losyon ve süspansiyon gibi formlarda olabilmektedir. Pomadlar; yagli bir sivag içinde etkin maddenin çözündügü veya disperse edildigi, tek fazli yari kati preparatlardir. Kremler ise yag fazi, su fazi ve emülgatörden olusan, en az iki fazli yari kati preparatlardir. Kremler genellikle su bazli ürünlerdir, daha yüzeysel cilt sorunlari veya günlük bakim ürünleri olarak kullanilmaktadir. Pomadlar ise yag bazli ve daha yogun kivamli ürünlerdir, derinin daha alt tabakasina kadar etki edebilir. Kremler su bazli maddelerden olustuklari için kivamlari daha ciVik ve daha kolay sürülebilmektedir. Pomatlar ise daha koyu kivamli ve yogun yagli bir yapiya sahiptir. Bu yüzden kremlere göre çok daha uzun süre kalarak deri altina nüfuz etmesine yardimci olur. Kozmetik ürünlerde oldukça sik karsilasilan bir sistem olan emülsiyon, birbiri içinde çözülmeyen SlVl- SlVl karisimlarina verilen addir. Miktarca az olan SlVl diger SlVl içerisinde dagilmis durumdadir. Emülsiyonlari kararli kilmak için sürfaktan özellikli maddeler olan emülgatörler kullanilir. Sürfaktanlar yüzey gerilimini düsürerek bir yüzey için daha kararli bir yapi olustururlar, böylece faz ayrimi önlenerek düzensiz yayilma engellenmis olur. Farmasötik veya kozmetik amaçla kullanilan emülsiyonlar fazlarina göre su içinde yag (Y/ S) ve yag içinde su (S/Y) olmak üzere 2 siniftir. Su içinde yag emülsiyonlari, suyla yikamak suretiyle temizlenebilir. Emülsiyonun ana maddesi sudur ve suyun cilt ile temasi yagdan daha fazladir. Bu suyun bir kismi, cilt tarafindan emilerek hizli bir nemlenme etkisi yaratir. Ürüne daha fazla su çekmesi için suya eklenen humektantlar (nem çekici), bu nemlendirme etkisini artirirlar. Bu özelliklerinden dolayi nemlendirici kremler ve makyaj alti kremleri gibi gündüz kremlerinin yapiminda tercih edilirler. Yagin miktari daha düsük oldugu ve ciltte su buharlastigi zaman deri üzerinde, çok daha ince yumusatici bir tabaka biraktigi için yag içinde su (S/Y) emülsiyonlarina nazaran daha hafif kremler elde edilir. Suyun buharlasmasina bagli olarak ciltte serinlik etkisi yaratir. Yag içinde su emülsiyonlari, su ile kolaylikla karismaz ve yalnizca su ile ciltten temizlenemez. Bir bezle silinerek, yag çözücü veya temizleyici kullanilarak çikartilabilir. Bilesimindeki su yavas buharlastigi için, çok az serinlik yaratirlar. Yag orani daha fazla oldugu için yagin deri ile temasi suya oranla daha fazla olur, bu sebeple daha yaglandirici ve emicidirler, su içinde yag emülsiyonlarina göre daha koyu kivamli ve yaglidir. Bu özellikleri sayesinde daha çok gece kremleri, masaj kremleri ve temizleme kremlerinde kullanilirlar. Isigi fazla yansitma ve cilde parlaklik verme etkileri vardir. Ancak gece kremlerinde ve ciltte çok kisa süre kalan kremlerde kullanildiklari için bu etkileri önemli degildir. Ciltte nemli ve yumusak bir etki birakmalari için kozmetik emülsiyonlar, ciltte belli bir süre kalmalidir. Nemlendirici kremler ve gece kremleri, cilt ile çok kisa süreli temasi olan temizleyici ve masaj kremlerine nazaran daha yararlidir (Sekil 1). US 1 0646425 nolu patent dökümaninda asetik asit ve dogal esansiyel yaglari da içeren cilt için kozmetik bir üründen bahsedilmektedir. Daha spesifik olarak, bu doküman, cildi tahris etmeyen, hizli etki eden ve derinlemesine nüfuz eden bir topikal analjezik saglayan hassas ciltler için bir topikal analjezik ile CN112641669A nolu Çin basvurusunda çapraz bagli hyaluronik asit veya bunun bir tuzu, çapraz bagli olmayan hyaluronik asit veya bunun bir tuzu, gliser0glukozit ve madecassoside içeren bir bilesimden ve bu ürünün cilt nemlendirici ve sikilastirici özellikli bir kozmetik hazirlanmasinda kullanimindan bahsetmektedir. EP2400943B1 nolu patent dökümani emülsiyon olarak cilde uygulanmaya yönelik kozmetik veya farmasötik olarak hazirlanmis krem veya losyon formunda olabilen bir müstahzar ile ilgilidir. Bu bulusta ayrica ürün formülasyonunun kullanim öncesi birbirine karistirilabilen yag fazi ve su fazi olmak üzere iki ayri fazdan olusan bir bilesim oldugu açiklanmaktadir. Teknigin bilinen durumunda karsilasilan bir diger EP0923937B1 patenti genel cilt bozukluklarinin tedavisi için terapötik ve kozmetik uygulamalar olarak faydali bir bitkisel formülasyondan bahsetmektedir. Bu patentte bahsi geçen formülasyon hem terapötik hem de kozmetik uygulamalar için gelistirilmistir. Fakat herbal olarak tanimlanmasina karsin içeriginde kimyasal bilesenler barindirmaktadir. Sonuç olarak, teknigin bilinen durumunda karsilasilan durumlara, mevcut çözümlerin konu hakkindaki yetersizligi nedeniyle kozmetik sektöründe ciltte olusan tahrisi onarici ve iyilestirici, cildi yatistirici, cildin nem bariyerini koruyucu, ciltteki kizarikliklari giderici, ciltte olusan çizgiler ve yariklari doldurucu ve antioksidan etki saglayan ve tüm bu etkileri bir arada sunabilen tamamen dogal yeni bir ürüne ihtiyaç dogmustur. BULUSUN KISA AÇIKLAMASI Mevcut bulusta, 7 farkli bitki özünün birlesimi ile olusturulan, dogal yapida, onarici ve iyilestirici özellik gösteren tercihen pomad yapida bir krem gelistirilmesi amaçlanmistir. Bulus konusu ile hedeflenen; ciltte olusan tahrisi onarici ve iyilestirici özellik göstermesinin yaninda cildi yatistirici, cildin nem bariyerini koruyucu, ciltteki kizarikliklari giderici, ciltte olusan çizgiler ve yariklari doldurucu ve antioksidan etki saglayan bitki çesitleri kullanilarak birden çok olumlu etkiyi ayni anda sunabilme özelligine sahip temiz içerikli ve dogal bir cilt kremi üretmektir. Bulusta bahsi geçen krem içerik ve etki alani açisindan tercihen pomad (merhem) yapida, yagli ve yogun kivamli oldugu için, bundan sonra bulusta, pomad yapili krem olarak adlandirilacaktir. Bulus konusu krem içerigi ve bunun üretim prosesi ile tamamen temiz içerikli ve ciltte iyilesme saglayan güçlü bir ürün üretilmesi amaçlanmaktad1r. Burada temiz içerikten kasit kimyasallardan uzak tamamen organik bilesenlerdir. Bulus konusu onarici ve iyilestirici etkili krem içeriginin üretim prosesinde de benzer sekilde kimyasal kullanilmamaktadir. Ayni zamanda bulus konusu pomad yapili krem içeriginin üretim prosesi kisa süreli basit islemlerden olusmakta, böylelikle hem üretim prosesi için hem de elde edilen ürün için bir avantaj saglamaktadir. SEKILLERIN AÇIKLANMASI Sekil.1: Su içinde yag (Y/ S) emülsiyonu A: Yag Fazi B: Su Fazi C: Emülgatörler BULUSUN DETAYLI AÇIKLAMASI Bu bölümde bulus konusu krem ve üretim yöntemi, konunun daha iyi anlasilabilmesi açisindan, bunlarla sinirli kalmamak ve sinirlayici bir etki olusturmamak kosuluyla belirli örneklerle açiklanmaktadir. Bulus ile, cildin tüm yüzeyi için kullanima uygun onarici ve iyilestirici, nemlendirici, yatistirici, kizariklik giderici, çizgileri ve yariklari doldurucu ve antioksidan etkileri sunabilen çok amaçli bir cilt kremi ve üretim yöntemi açiklanmaktadir. Bulusta bahsi geçen ürün, cildi onarici ve iyilestirici, yatistirici özellik tasimasi, kremlerden daha yagli ve yogun kivamli bir ürün oldugu için içerik ve etki alani açisindan pomad (merhem) yapisinda bir ürün olarak nitelendirilmekte ve bundan sonra bulusta, pomad yapili krem olarak belirtilmektedir. Bulusun bir diger yönü ise ürünün temiz içerikli olarak dogal yapiyi saglayacak sekilde hazirlanmasidir. Cilt sagligi için çesitli faydalari bulunan birçok organik bilesenden olusmasi ise bulusun bir avantaj idir. Bulusun bir baska üstünlügü de piyasada sunulan diger iyilestirici ve onarici özellikleri oldugu belirtilen kremlere alternatif olarak ürün içeriginin tamamen dogal içerikten hazirlanmasi ve uzun yillardir alternatif tip üzerinde de kullanilan çesitli bitkilerin entegrasyonu ile olusturulacak olmasidir. Bulus 7 farkli bitki özünün karisimini içermektedir; bunlar Kaplan Otu özü (Centella Asiati'ca), kirmizi pancar kökü (Beta Vulgari's), cadi findigi yapragi (Hamameli's Virginiana), okka gülü (Rosa x Centi'foli'a), ayni sefa (Calendula Oßi'ci'nali's), papatya (Chamomi'lla Recuti'ta), zerdeçal (Curcuma Longa),dir. Bulusta hedeflenen bir diger nokta da tek ürünle birden çok etkiyi bir arada sunabilmektir; örnegin; 0 yatistirici özellik saglamak, cildin nem bariyerini korumak, cilt kizarikligini gidermek, ciltte olusan çizgiler ve yariklari dolgunlastirmasi için Centella Asiati'ca (Kaplan otu) bitkisinin glikosile triterpeni olan Madecassoside, bundan sonra bulusta Madecassoside olarak belirtilecektir, o tahrisi azaltmak ve iyilestirici etkili ayni sefa (Calendula Oyýîcinali's) ve kirmizi pancar (Beta Vulgari's) bitkileri, o cildin nem seViyesinin korunmasi ve ürünün antioksidan özelligi gösterebilmesi için Zerdeçal (Curcuma Longa), Papatya (Chamomi'lla Recuti'ta) 0 cilt üzerinde astrinjen (sikilastirici, yatistirici) etki saglayabilmek için ise cadi findigi yapragi (Hamameli's Virginiana) ve okka gülü (Rosa x Centi'foli'a) kullanilmistir. Tahris olmuslugu azaltmak ve iyilestirici etkisinden faydalanmak amaciyla ayrica ak sögüt agaci (Salix alba) ve kimyondan (Cumi'num cymi'num) elde edilen isopropil benzil salisilat ve isodesil salisilat kombinasyonu kullanilmaktadir. Deri inflamatuar yanitinin lokal bir kutanöz modülatörü olarak isleV gören uzun zincirli salisilik asit esterlerinden olusur. Keratoplastik (keratin üretimini hizlandirici) aktiViteye sahip bir anti-lipoperoksidan olarak karakterize edilen epidermal dönüsümü optimize eder; kutisin görünümünü iyilestirir ve cildin bariyer etkisini güçlendirir. 0t-hidroksi asitlere fizyolojik bir alternatif olarak cilt parlakligina da katki saglar. Ayni zamanda yara ve yanik dokularinda açiga çikan yag dokunun perokside olmasini engelleyerek çok hizli bir iyilesme sürecine eslik eder. Çok sayida hastaliga ve cilt sorununa faydalari bulunan sari ve turuncu renklerde olabilen Calendula Oßi'ci'nali's (Ayni sefa) bitkisi, Akdeniz ülkelerinde ve Kanarya Adalari bölgesinde yetisir. Aynisefa çiçegi; calendula, portakal nergisi, altincik, marigol, souci ve ölü çiçegi gibi farkli isimlerle anilabilir. Cilt üzerinde yaslanmaya bagli etkileri ortadan kaldirma, cilt üzerinde olusan tahribatin önlenmesi, siVilceleri önleyici etki göstermesi, nemlendirici etki saglamasi, kizariklarin azalmasina yardimci olmasi, cilt lekelerini azaltmasi, göz çevresinde olusan morluk ve halka görünümünün azaltilmasina yardimci olmasi gibi etkileri vardir. Kirmizi pancar (Beta Vulgari's) mükemmel bir kozmetik üründür. Cildin ve saçin güzelligini korumak için kullanilir. Pancar kökü, cilde inanilmaz derecede iyi fayda saglayan bir sebze olarak tanimlanmistir. Pancar, içerdigi bol antioksidanlar ve C Vitamini, A ve K seViyeleri ile Vücudu detoksifiye eder ve temizler, iltihabi azaltir ve erken yaslanmayi önler. Son yillarda, dogal antioksidanlar, güvenilir olmasi ve istenmeyen yan etkileri olmamasi nedeniyle sentetik antioksidanlara kiyasla daha fazla tercih edilir duruma gelmislerdir. Antioksidan özellik gösteren birçok bitki ve baharat labiatae familyasina aittir. Labiatae familyasina ait cinsler özellikle terpenik bilesikleri (mono-, di-, triterpenler) flavonoid, fenolik asitleri içermesi nedeniyle önemli fizyolojik aktivitelere (antioksidan ve antimikrobiyal) sahip bitkileri içermektedir. Bu tarz bitkiler, bunlarla sinirli olmamak kosuluyla, biberiye (Rosmari'nus oßi'ci'nali's), lavanta (Lavandula hybrida), kekik (Thymus vulgari's), Mercankösk (Origanum majorana), yarpuz (Mentha pulegi'um), nane (Mentha), ada çayi (Salvi'a), feslegen (Oci'mum basili'cum), melisa (Melissa oßi'ci'nali's) ve ballibaba (Lamium), dir. Antioksidan etkili bazi bitki özlerinin nemlendirici etkisi de oldugu ve ciltteki iltihaplarda azalma veya düzelme sagladigi bilinmektedir. Bu yüzden ürün içerigine cildin nem seViyesinin korunmasi ve ürünün antioksidan özellik gösterebilmesi için Zerdeçal (Curcuma Longa), Papatya (Chamomi'lla Recuti'ta) gibi bitki özleri de kullanilmistir. Bulusta cilde uygulamaya yönelik hazirlanan pomad yapili krem formülasyonu emülsiyon formunda hazirlanacaktir. Emülsiyonlar birbirine karismayan iki siVinin birbiri içinde dagilmasindan olusmus homojen görünüslü heterojen sistemlerdir. Bulusun konusu pomad yapili krem için tercih edilen emülsiyon sistemi su içinde yag (Y/S) emülsiyonu seklindedir. Su içinde yag emülsiyonlari suyla yikamak suretiyle temizlenebilir. Emülsiyonun ana maddesi sudur ve suyun cilt ile temasi yagdan daha fazladir. Bu suyun bir kismi, cilt tarafindan emilerek hizli bir nemlenme etkisi yaratir. Ürüne daha fazla su çekmesi için suya eklenen humektantlar (nem çekici), bu nemlendirme etkisini artirirlar. Bu özelliklerinden dolayi nemlendirici kremler ve makyaj alti kremleri gibi gündüz kremlerinin yapiminda tercih edilirler. Yagin miktari daha düsük oldugu ve ciltte su buharlastigi zaman deri üzerinde, çok daha ince yumusatici bir tabaka biraktigi için yag içinde su emülsiyonlarina nazaran daha hafif kremler elde edilir. Suyun buharlasmasina bagli olarak ciltte serinlik etkisi yaratir. Krem formülasyonlarinda kullanilan emülgatörlerden bazilari parafin, setearil alkol, polisorbat 20 ve setearet 20, gliseril stearat, poligliseril-3 pirinç branat, sükroz stearat, setearil olivat, sorbitan olivat ve behenil alkol olarak siralanabilir. Emülgatörler ayni zamanda kremler veya losyonlar gibi formüllerin dokusunu ve emülsiyonlarin kararliligini arttirdigi için stabilizatör ajani olarak da göreV alirlar. Bulusta tercih edilen emülgatör ve stabilize edici ajanlar gliseril stearat, poligliseril-3 pirinç branat, sükroz stearat, setearil alkol, setearil olivat, sorbitan olivat ve behenil alkoldür. Kremlerin daha yogun kivamlari oldugu göz önüne alindiginda baglayici özellikli kimyasallarin istenilen kivamda ürün elde edebilmek için formülasyonlara eklenmesi gerekmektedir. Bu kimyasallar çogu zaman kivam arttirma özelliklerinin yaninda sürfaktan, deri yumusatma Vb. özellikler de tasirlar. Bulusta, yumusatici ve nemlendirici etkili maddeler olarak gliserin, gliseril kaprilat/kaprat, kaprilik/kaprik trigliserit, lavanta esansiyel yagi, izopropil miristat, amino asitler, laktatlar, üre, ürik asit, NH3, glukozamin, kreatin, sitratlar, sukroz, organik asitler, peptitler, sorbitol, PEG, pantenol türevleri kullanilabilir. Antioksidan etki gösteren maddeler tokoferol, mineraller (selenyum, bakir, demir, çinko ve manganez), vitaminler (C ve E), bütillenmis hidroksi anisol (BHA), bütillenmis hidroksitoluen (BHT), propil galat, fitoantioksidanlar (polifenol ve terpenler), antosiyanin, proantosiyanin, arbutin, azelaik asit, kurkumin, epigallokatesin-3 -gallat ve kuersetin olabilir. Bulusta antioksidan madde olarak tercihen tokoferol seçilir. Cilt iyilestirici, düzenleyici, onarici, yatistirici etkili madde olarak Madecassoside içerir, shea yagi (Butyrospermum parki'i'), soya fasulyesi (Glyci'ne Soja) yagi, ayni sefa (Calendula Oyýfi'ci'nali's) çiçek ekstresi, fruktooligosakkaritler, kirmizi pancar (Beta Vulgari's) kök ekstresi, isopropil benzil salisilat ve isodesil salisilat, vitamin F, papatya (Chamomilla Recutita) çiçek ekstresi, biberiye (Rosmari'nus Oyýfi'ci'nali's) esansiyel yagi, limon (Citrus limon) esansiyel yagi kullanilabilir. Koruyucu madde olarak sodyum benzoat, potasyum sorbat, fenoksietanol, benzoik asit, dehidroasetik asit kullanilabilir. Cilt üzerinde astrinjen (sikilastirici, yatistirici etkili) özellik saglayan maddeler olarak cadi findigi (Hamameli's Virginiana), okka gülü (Rosa x Centi'foli'a), elma sirkesi, papatya (Chamomilla Recutita), limon (Citrus limon), yesil çay (Camelli'a sinensi's), ayni sefa (Calendula Oyýfi'ci'nali's) bitkisi ve çay agaci (Melaleuca alterni'foli'a) tercih edilebilir. Tamponlayici ajan olarak sodyum hidroksit, amonyum hidroksit, kalsiyum hidroksit, magnezyum hidroksit ve potasyum hidroksit kullanilabilir. Parfüm ve koku verici ajanlar olarak metil eugenol, zerdeçal ekstresi, nane yagi, portakal yagi, limon yagi, sandal agaci gibi aromatik yaglar kullanilabilir. Çözücü olarak su ve pentilen glikol kullanilmistir. Bulusta esas olarak 7 farkli bitki özünün birlesimi ile olusturulan, onarici ve iyilestirici özellik gösteren pomad yapisinda bir krem formu gelistirilmesi amaçlanmistir. Petrol türevleri olan vazelin vb. gibi sentetik kökenli hammaddeler kullanilmamasi ürünün avantajlarindan bir tanesidir. Dogal içerikli koruyucular kullanilmasi ve yapilan testler ile etkinliginin saglanmis olmasi da bir diger avantajidir. Böylelikle zararli kimyasallar olmadan hazirlanabilen dogal yapida, çevre dostu, içerigindeki bitkiler ile çesitli çevresel faktörlerden dolayi tahris olan cildin iyilestirilmesi ve onarilmasina fayda saglayabilecegi düsünülen pomad yapili kremin kisisel bakim ve kozmetik alaninin en önemli ürün gruplarindan bir tanesi olacagi düsünülmektedir. Ayni zamanda bulus konusu pomad yapili krem içeriginin üretim prosesinin kisa süreli basit islemlerden olusmasi ve tercih edilen ambalajin çevre dostu ve geri dönüstürülebilir özellikli alüminyum tüpler olmasi hem üretim prosesi için hem de elde edilen ürün için bir avantaj saglamaktadir. Ayrica ürünün çevreyi korumaya yönelik bir ürün oldugunu göstermektedir. Bulus konusu cildin tüm yüzeyi için kullanima uygun olan ürünün sasirtici bir sekilde onarici ve iyilestirici, nemlendirici, yatistirici, kizariklik giderici, çizgileri ve yariklari doldurucu ve antioksidan etkileri gibi birden çok etkiyi gösterdigi gözlenmistir. Bulusun bir diger avantaji ise ürünün cilt sagligi için çesitli faydalari bulunan birçok organik bilesenden ve uzun yillardir alternatif tip üzerinde de kullanilan çesitli bitkilerin entegrasyonu ile olusturulmasidir. Bulus konusu ürünün dogal yapili bir ürün formunda hazirlanmasi sayesinde insan sagligi açisindan yan etkileri diger kremlere göre minimum düzeyde olacaktir. Dogal yapida hazirlanan pomad yapili kremde herhangi bir kimyasal madde kullanilmamis olmasi kremimizin en önemli avantajlarindan biridir. Bu sayede bulus ile elde edilen krem hemen hemen her yas grubunda kullanima uygun bir yapiya sahip olacaktir. Bulusun bir baska amaci ise; kozmetik sektöründe alternatif ürün konusunda katki saglamak, insanlarin cilt sagligina verdigi önem dogrultusunda ihtiyaç duydugu tüm özellikleri bir arada bulabilecegi yeni bir ürün seçenegi sunarak fayda saglamaktir. 7 çesit bitkiden faydalanilarak her bir bitkinin sahip oldugu olumlu etkileri tek bir konsantrasyon içerisinde barindirilmaktadir. Bitkilerin sundugu olumlu etkiler; - Cildi nemlendirmesi, yumusatmasi, nem bariyerini korumasi - Tahris olmuslugu azaltmasi, cildi yatistirmasi ve iyilestirmesi - Yara, iz ve yariklarin önemli derecede giderici ve tedavi edici özellige sahip olmasi - Ciltte olusan kizarikliklari gidermesi - Ciltte olusan çizgiler ve yariklari dolgunlastirmasi - Antioksidan özelliklere sahip olmasidir. Bulusun özellikleri asagidakilerle sinirli kalmamak üzere örnekler asagida verilmistir: Bulusta, 7 çesit bitki özünden faydalanilarak hazirlanan dogal yapida tahris olmus cildi onarici, iyilestirici ve nemlendirme etkili tüm vücut ve her yas grubu için kullanima uygun pomad yapili krem formülasyonunun asagidakileri içermesi planlanmaktadir: - agirlikça %0.00001-15 bir veya daha fazla cilt iyilestirici, yatistirici ve düzenleyici madde - agirlikça %0.01-7 bir veya daha fazla astrinj en (doku büzücü, yatistirici etkili) madde - agirlikça %0.01-10 bir veya daha fazla nemlendirici madde - agirlikça %0.001-20 bir veya daha fazla yumusatici madde - agirlikça %0, 1- 15 bir veya daha fazla emülgatör - agirlikça %0, 1-7 bir veya daha fazla emülsiyon stabilize edici madde - agirlikça %0.0001-1 bir veya daha fazla antioksidan - agirlikça %0.00001-0.1 bir veya daha fazla koruyucu madde - agirlikça %0.0001-0.1 bir veya daha fazla tamponlayici ajan - agirlikça %0.00001-0.1 bir veya daha fazla parfüm ve koku verici ajanlar - agirlikça %0.01-85 bir veya daha fazla çözücü. Bulusta, 7 çesit bitki özünden faydalanilarak hazirlanan dogal yapida, tahris olmus cildi onarici, iyilestirici ve nemlendirme etkili tüm Vücut ve her yas grubu için kullanima uygun pomad yapili krem formülasyonu asagidakileri içermesi ile karakterizedir: - agirlikça %0.00001-15 Madecassoside, shea yagi (Bulyrospermum parki'i'), soya fasulyesi (Glyci'ne Soja) yagi, ayni sefa (Calendula Oyýfi'ci'nali's) çiçek ekstresi, fruktooligosakkaritler, kirmizi pancar (Beta Vulgari's) kök ekstresi, isopropil benzil salisilat ve isodesil salisilat, Vitamin F, papatya (Chamomi'lla Recuti'ta) çiçek ekstresi, biberiye (Rosmari'nus Oyýfi'ci'nali's) esansiyel yagi, limon (Citrus limon) esansiyel - agirlikça %0.01-7 cadi findigi (Hamameli's Virginiana) yapragi ve okka gülü (Rosa x Centi'foli'a) - agirlikça %0.01-10 gliserin - agirlikça %0.001-20 gliseril kaprilat/kaprat, kaprilik/kaprik trigliserit ve lavanta (Lavandula Hybrida) esansiyel yagi - agirlikça %0,1- 15 gliseril stearat, poligliseril-3 pirinç branat, sükroz stearat, setearil alkol, setearil olivat ve sorbitan olivat - agirlikça %0, 1-7 behenil alkol - agirlikça %0.0001-1 tokoferol - agirlikça %0.00001-0.1 sodyum benzoat, potasyum sorbat, fenoksietanol, benzoik asit ve dehidroasetik - agirlikça %0.0001-0.1 sodyum hidroksit - agirlikça %0.00001-0.1 metil eugenol ve zerdeçal (Curcuma Longa) kök ekstresi - agirlikça %0.01-85 su ve pentilen glikol. Üretim prosesi: A bilesenleri, B bilesenlerine eklenerek karistirilir. Üzerine C bilesenleri ilave edilir ve karistirmaya devam edilir. D bilesenleri elde edilen karisima eklenir ve karistirilir. Son olarak E bilesenleri ilave edilerek karistirilmaya devam edilir ve nihai ürün elde edilir. Burada bahsi geçen bilesenler asagida belirtildigi sekildedir: B: Kaprilik/Kaprik Trigliserit, Gliseril Stearat, Poligliseril-3 Pirinç Branat, Setearil Alkol, Sükroz Stearat, Behenil Alkol, setearil Olivat, Sorbitan Olivat, shea yagi (Bulyrospermum parkii), Ayni sefa (Calendula Oficinalis) çiçek ekstresi, Soya fasulyesi (Glyci'ne Soja) yagi, Tokoferol C: isopropil benZil salisilat ve isodesil salisilat D: Fruktooligosakkaritler, Kirmizi Pancar (Beta Vulgari's) Kök Ekstresi, Zerdeçal (Curcuma Longa) Kök Ekstresi, Linoleik Asit, Linolenik Asit, Cadi findigi (Hamameli's Virginiana), Papatya (Chamomi'lla Recutita) Çiçek Ekstresi, Pentilen Glikol, Gliseril Kaprilat/Kaprat E: Biberiye (Rosmarinus Oßicinalis) Esansiyel Yagi, Limon (Citrus limon) Esansiyel Yagi, Lavanta (Lavandula Hybrida) Esansiyel Yagi, Okka Gülü (Rosa x Centi'foli'a), Sodyum Hidroksit. Elde edilen dogal içerikli kremin sürdürülebilir bir yapisi olmasi ve stabilite testleri yapildiktan sonra içerigin kimyasal maddeleri içermedigini kanitlayabilmek amaciyla mikrobiyoloji testleri (Tablo 1), koruyucu etkinlik (Challenge) testleri (Tablo 2) ve parfüm içermeZ testi (Tablo 3) uygulanmistir. Elde edilen veriler ile hedeflenen ürün ile ilgili belirlenen kriterlerin saglandigi gözlenmis ve ürünün üretimi ve kullanimi açisindan herhangi bir problem olmadigi sonucuna varilmistir. Tablo 1. Mikrobiyolojik Test Sonuçlari Numunenin Ön Mikrobiyoloj ik Testi Sonuç Metot Limit Degerlendirme *Staphylococcus aureus Aranmasi Tespit edilemedi ISO 22718 Bulunmamali Uygun *Escherichia coli Aranmasi Tespit edilemedi ISO 21150 Bulunmamali Uygun *Candida albicans Aranmasi Tespit edilemedi ISO 18416 Bulunmamali Uygun *Pseudomonas aeruginosa Aranmasi Tespit edilemedi ISO 22717 Bulunmamali Uygun Tablo 2. Koruyucu Etkinlik (Challenge) Testi Inokülasy Numune Sayimi, Düsüs, on (Cfu) kob/g [Nx=C/(de)] Log [Rx=IgN0-IgNx] Tablo 3. Parfüm Içermez Testi Analizler Sonuçlar Uygunluk Analiz Metodu Sentetik Parfüm IçermeZ Analizi cm'1 Tespit Edilmedi DY In House Method (Infrared Spectrum) Ayrica dermatolojik testler 25 denek üzerinde uygulanarak gözlemlenmistir. denek üzerinde yapilan yama testlerine göre o Ürünün herhangi bir tahris edici etkisi olmadigi 0 Cilt tolerans testinin gereksinimlerini karsiladigi 0 Insan sagligi güvenlik özellikleri beyan edilmis kozmetik ürünlerin gereksinimlerini karsiladigi kanitlanmistir. TR TR TR DESCRIPTION POMAD CREAM TECHNICAL FIELD The invention relates to a pomade-based cream that has a supportive effect on the healing and repair of skin irritated by various environmental factors and its production method. The cream subject to the invention contains natural and organic ingredients. KNOWN STATE OF THE TECHNOLOGY Cosmetic products for hair, skin, face, nails, etc. They are known as preparations that provide cleansing, scenting, appearance changing, protective and sometimes healing and restorative effects depending on the content, suitable for use in various areas such as. Some chemicals contained in cosmetic products can cause various negative effects on human health, and users may be exposed to the negative effects of chemicals without realizing it during the day. These chemicals contained in cosmetic products harm not only the user but also the environment (water, soil, air) and therefore all living creatures living in nature. Recently, consumers' faith in synthetic products has decreased due to side effects rather than benefits, and therefore, the tendency towards natural herbal products has increased. The criteria for choosing the product are that it has clean ingredients, is natural, and that the product used can offer multiple effects together. In order to meet these needs, companies have started to highlight information about the contents of the product in their product advertisements or on their packaging (Does not contain paraben, siles, natural content, herbal, etc.). It is known that all or some of the plants have been used for various skin disorders for centuries. However, based on scientific studies, clinical trials, and review of pharmacological tests, it appears that plants have very large amounts and complex structures of phytochemicals that heal and repair the skin. Biodegradable products, which tend to dissolve and decompose in a system that involves the aerobic or anaerobic breakdown of organic substances by enzymes produced in living organisms, can be dissolved without harming nature. Therefore, the fact that the materials used in cosmetic products are environmentally friendly, recyclable or biodegradable is a reason for preference by both manufacturers and consumers. A biodegradable cosmetic product should not contain microplastics, silicone types and materials ending in "-kon, -konol", "-siloxane" that appear under different names. Centella Asiati'ca plant, which creates miracles in skin care, is most commonly known as Gotu Kola (Tiger Grass). This plant, which has an indispensable place in the content of South Korean cosmetic products, is also used in the health sector due to its therapeutic properties. The Centella Asiati'ca plant has anti-aging properties on the skin, preventing problems such as wrinkles and sagging that occur as a result of aging, ensuring the disappearance of scars after acne and wound healing, showing a healing effect on wounds, being suitable for sensitive skin, and making the skin more sensitive. It has benefits such as calming and repairing the skin barrier. Centella Asiati'ca plant contains active components madecassoside, asiaticoside, asiatic acid and madecasic acid. Madecassoside is a highly purified glycosylated triterpene of Centella Asiati. It is an active ingredient suitable for use in anti-aging, sensitive skin, very dry skin and mature skin applications. Madecassoside activates collagen expression, normalization of hyperproliferation of keratinocytes, global anti-inflammatory properties and a visible effect on excessive desquamation. Cosmetic products used for local application on the skin can be in forms such as cream, ointment, gel, lotion and suspension. Pomades; They are single-phase semi-solid preparations in which the active ingredient is dissolved or dispersed in an oily liquid. Creams, on the other hand, are semi-solid preparations with at least two phases, consisting of an oil phase, a water phase and an emulsifier. Creams are generally water-based products and are used for more superficial skin problems or as daily care products. Pomades, on the other hand, are oil-based and more dense products, and can affect the lower layer of the skin. Since creams consist of water-based substances, their consistency is more viscous and they can be applied more easily. Pomades, on the other hand, have a thicker consistency and a denser oily texture. Therefore, it stays longer than creams and helps it penetrate under the skin. Emulsion, a system that is frequently encountered in cosmetic products, is the name given to SLVl-SLVl mixtures that do not dissolve in each other. The LVL that is less in amount is distributed within the other LVL. Emulsifiers, which are substances with surfactant properties, are used to stabilize emulsions. Surfactants create a more stable structure for a surface by reducing surface tension, thus preventing phase separation and preventing uneven spreading. Emulsions used for pharmaceutical or cosmetic purposes are divided into two classes according to their phases: oil in water (O/S) and water in oil (W/O). Oil-in-water emulsions can be removed by washing with water. The main ingredient of the emulsion is water, and water has more contact with the skin than oil. Some of this water is absorbed by the skin, creating a rapid moisturizing effect. Humectants added to the water to attract more water to the product increase this moisturizing effect. Due to these properties, they are preferred in the production of day creams such as moisturizing creams and under-make-up creams. Since the amount of oil is lower and when the water evaporates on the skin, it leaves a much thinner softening layer on the skin, lighter creams are obtained compared to water-in-oil (W/O) emulsions. It creates a cooling effect on the skin due to the evaporation of water. Water-in-oil emulsions do not mix easily with water and cannot be removed from the skin with water alone. It can be removed by wiping with a cloth or using a degreaser or cleaner. Since the water in their composition evaporates slowly, they create very little coolness. Since the oil content is higher, oil has more contact with the skin than water, therefore they are more lubricating and absorbent, and are thicker and oilier than oil-in-water emulsions. Thanks to these properties, they are mostly used in night creams, massage creams and cleansing creams. It has the effect of reflecting more light and giving shine to the skin. However, these effects are not important since they are used in night creams and creams that stay on the skin for a very short time. Cosmetic emulsions must remain on the skin for a certain period of time in order to leave a moist and soft effect on the skin. Moisturizing creams and night creams are more beneficial than cleansing and massage creams, which have very short-term contact with the skin (Figure 1). In the patent document numbered US 1 0646425, a cosmetic product for the skin containing acetic acid and natural essential oils is mentioned. More specifically, this document describes a topical analgesic for sensitive skin that does not irritate the skin, provides a fast-acting and deeply penetrating topical analgesic, and cross-linked hyaluronic acid or a salt thereof, non-cross-linked hyaluronic acid or a salt thereof, in Chinese application CN112641669A. It mentions a composition containing salt, glycerol-glucoside and madecassoside and the use of this product in the preparation of a cosmetic with skin moisturizing and firming properties. Patent document numbered EP2400943B1 relates to a preparation that can be in the form of a cosmetic or pharmaceutical cream or lotion for application to the skin as an emulsion. This invention also explains that the product formulation is a composition consisting of two separate phases, the oil phase and the water phase, which can be mixed together before use. Another patent EP0923937B1, encountered in the state of the art, mentions a herbal formulation useful as therapeutic and cosmetic applications for the treatment of general skin disorders. The formulation mentioned in this patent was developed for both therapeutic and cosmetic applications. However, although it is defined as herbal, it contains chemical components. As a result, due to the inadequacy of the existing solutions in the known state of the art, in the cosmetic industry, products that repair and heal the irritation on the skin, soothe the skin, protect the skin's moisture barrier, eliminate redness on the skin, fill the lines and crevices on the skin and provide antioxidant effect and all these effects are presented. There is a need for a new, completely natural product that can offer both products together. BRIEF DESCRIPTION OF THE INVENTION In the present invention, it is aimed to develop a cream, preferably with a pomade structure, that has a natural structure and restorative and healing properties, created by the combination of 7 different plant extracts. The aim of the invention is; It is a natural skin cream with clean ingredients that has the ability to offer multiple positive effects at the same time by using plant varieties that have repairing and healing properties of skin irritation, soothing the skin, protecting the skin's moisture barrier, eliminating redness on the skin, filling the lines and crevices on the skin and providing antioxidant effect. is to produce. Since the cream mentioned in the invention preferably has a pomade (ointment) structure, oily and dense consistency in terms of its content and area of effect, it will be referred to as pomade cream from now on. It is aimed to produce a strong product with completely clean content and providing improvement to the skin, with the cream content of the invention and its production process. What we mean by clean content here is completely organic ingredients, away from chemicals. Similarly, no chemicals are used in the production process of the restorative and healing cream content of the invention. At the same time, the production process of the pomade-based cream content of the invention consists of short-term simple processes, thus providing an advantage for both the production process and the product obtained. DESCRIPTION OF THE FIGURES Fig.1: Oil in water (O/W) emulsion A: Oil Phase B: Water Phase C: Emulsifiers DETAILED DESCRIPTION OF THE INVENTION In this section, the cream and the production method of the invention are discussed in order to better understand the subject, not to be limited to them and not to be limited to them. It is explained with specific examples, provided that it does not create any impact. The invention describes a multi-purpose skin cream and its production method that can be used on the entire surface of the skin and can offer restorative and healing, moisturizing, soothing, redness-relieving, lines and crevices-filling and antioxidant effects. The product mentioned in the invention is described as a product with a pomade (ointment) structure in terms of its content and area of effect, since it has skin repairing, healing and soothing properties, and is a product with a more oily and dense consistency than creams, and is henceforth referred to as a pomade structure cream in the invention. Another aspect of the invention is that the product is prepared with clean ingredients to provide a natural structure. An advantage of the invention is that it consists of many organic components that have various benefits for skin health. Another advantage of the invention is that, as an alternative to other creams offered on the market that are said to have healing and restorative properties, the product content is prepared entirely from natural ingredients and will be created by the integration of various herbs that have been used in alternative medicine for many years. The invention contains a mixture of 7 different plant extracts; These are Tiger Herb extract (Centella Asiati'ca), red beet root (Beta Vulgari's), witch hazel leaf (Hamameli's Virginiana), okka rose (Rosa x Centi'foli'a), calendula (Calendula Oßi'ci'nali's), chamomile (Chamomi'lla Recuti'ta), turmeric (Curcuma Longa). Another point aimed at the invention is to offer multiple effects together with a single product; for example; Madecassoside, which is the glycosylated triterpene of the Centella Asiati'ca (Tiger grass) plant, will be referred to as Madecassoside in the invention, to provide soothing properties, to protect the skin's moisture barrier, to eliminate skin redness, to plump the lines and crevices on the skin, it will be referred to as Madecassoside in the invention, it is used to reduce irritation and has a healing effect. (Calendula Oyýîcinali's) and red beet (Beta Vulgari's) plants, Turmeric (Curcuma Longa), Chamomile (Chamomi'lla Recuti'ta) to protect the moisture level of the skin and to provide antioxidant properties of the product. 0 to provide an astringen (firming, soothing) effect on the skin. Witch hazel leaf (Hamameli's Virginiana) and okka rose (Rosa x Centi'foli'a) were used for the preparation. In order to reduce irritation and benefit from its healing effect, the combination of isopropyl benzyl salicylate and isodecyl salicylate obtained from white willow tree (Salix alba) and cumin (Cumi'num cymi'num) is also used. It consists of long-chain salicylic acid esters that function as a local cutaneous modulator of the skin inflammatory response. Characterized as an anti-lipoperoxidant with keratoplastic (keratin production accelerator) activity, it optimizes epidermal transformation; It improves the appearance of cutis and strengthens the barrier effect of the skin. As a physiological alternative to 0t-hydroxy acids, it also contributes to skin brightness. At the same time, it accompanies a very rapid healing process by preventing the fatty tissue released in wound and burn tissues from being peroxidized. Calendula Oßi'ci'nali's (Calendula) plant, which can be in yellow and orange colors and has benefits for many diseases and skin problems, grows in the Mediterranean countries and the Canary Islands region. Calendula flower; It may be known by different names such as calendula, orange daffodil, goldenrod, marigold, souci and nectar. It has effects such as eliminating the effects of aging on the skin, preventing damage to the skin, preventing acne, providing a moisturizing effect, helping to reduce redness, reducing skin blemishes, and helping to reduce the appearance of bruises and circles around the eyes. Red beet (Beta Vulgari's) is an excellent cosmetic product. It is used to protect the beauty of skin and hair. Beet root has been described as a vegetable that provides incredibly good skin benefits. Beetroot, with its abundant antioxidants and levels of Vitamin C, A and K, detoxifies and cleanses the body, reduces inflammation and prevents premature aging. In recent years, natural antioxidants have become more preferred compared to synthetic antioxidants because they are reliable and do not have undesirable side effects. Many plants and spices with antioxidant properties belong to the labiatae family. The genera belonging to the Labiatae family include plants with important physiological activities (antioxidant and antimicrobial), especially because they contain terpenic compounds (mono-, di-, triterpenes), flavonoids and phenolic acids. Such plants include, but are not limited to, rosemary (Rosmari'nus oßi'ci'nali's), lavender (Lavandula hybrida), thyme (Thymus vulgari's), marjoram (Origanum majorana), pendant (Mentha pulegi'um), mint (Mentha ), sage (Salvi'a), basil (Oci'mum basili'cum), lemon balm (Melissa oßi'ci'nali's) and ballibaba (Lamium). It is known that some plant extracts with antioxidant effects also have a moisturizing effect and reduce or improve skin inflammation. For this reason, plant extracts such as Turmeric (Curcuma Longa) and Chamomile (Chamomi'lla Recuti'ta) were also used in the product content to protect the skin's moisture level and to ensure that the product has antioxidant properties. In the invention, the pomade cream formulation prepared for application to the skin will be prepared in emulsion form. Emulsions are heterogeneous systems with a homogeneous appearance, consisting of two immiscible liquids dispersed within each other. The preferred emulsion system for the pomade cream that is the subject of the invention is oil-in-water (O/W) emulsion. Oil-in-water emulsions can be removed by washing with water. The main ingredient of the emulsion is water, and water has more contact with the skin than oil. Some of this water is absorbed by the skin, creating a rapid moisturizing effect. Humectants added to the water to attract more water to the product increase this moisturizing effect. Due to these properties, they are preferred in the production of day creams such as moisturizing creams and under-make-up creams. Lighter creams are obtained compared to water-in-oil emulsions because the amount of oil is lower and when the water evaporates on the skin, it leaves a much thinner softening layer on the skin. It creates a cooling effect on the skin due to the evaporation of water. Some of the emulsifiers used in cream formulations can be listed as paraffin, cetearyl alcohol, polysorbate 20 and ceteareth 20, glyceryl stearate, polyglyceryl-3 rice branate, sucrose stearate, cetearyl olivate, sorbitan olivate and behenyl alcohol. Emulsifiers also serve as stabilizing agents, increasing the texture of formulas such as creams or lotions and the stability of emulsions. Preferred emulsifying and stabilizing agents in the invention are glyceryl stearate, polyglyceryl-3 rice branate, sucrose stearate, cetearyl alcohol, cetearyl olivate, sorbitan olivate and behenyl alcohol. Considering that creams have a thicker consistency, chemicals with binding properties must be added to the formulations to obtain the product with the desired consistency. These chemicals often act as surfactants, leather softeners, etc., in addition to their thickening properties. They also have features. In the invention, glycerin, glyceryl caprylate/caprate, caprylic/capric triglyceride, lavender essential oil, isopropyl myristate, amino acids, lactates, urea, uric acid, NH3, glucosamine, creatine, citrates, sucrose, organic acids, as softening and moisturizing active substances. Peptides, sorbitol, PEG, panthenol derivatives can be used. Substances with antioxidant effects are tocopherol, minerals (selenium, copper, iron, zinc and manganese), vitamins (C and E), butylated hydroxy anisole (BHA), butylated hydroxytoluene (BHT), propyl gallate, phytoantioxidants (polyphenols and terpenes), anthocyanin. , proanthocyanin, arbutin, azelaic acid, curcumin, epigallocatecin-3-gallate and quercetin. In the invention, tocopherol is preferably chosen as the antioxidant substance. Contains Madecassoside as a skin healing, regulating, repairing and soothing ingredient, shea butter (Butyrospermum parki'i'), soybean (Glyci'ne Soja) oil, calendula (Calendula Oyýfi'ci'nali's) flower extract, fructooligosaccharides, red Beetroot (Beta Vulgari's) root extract, isopropyl benzyl salicylate and isodecyl salicylate, vitamin F, chamomile (Chamomilla Recutita) flower extract, rosemary (Rosmari'nus Oyýfi'ci'nali's) essential oil, lemon (Citrus limon) essential oil can be used. Sodium benzoate, potassium sorbate, phenoxyethanol, benzoic acid, dehydroacetic acid can be used as preservatives. Witch hazel (Hamameli's Virginiana), okka rose (Rosa Camelli'a sinensi's), calendula (Calendula Oyýfi'ci'nali's) plant and tea tree (Melaleuca alterni'foli'a) can be preferred. Sodium hydroxide, ammonium hydroxide, calcium hydroxide, magnesium hydroxide and potassium hydroxide can be used as buffering agents. Aromatic oils such as methyl eugenol, turmeric extract, peppermint oil, orange oil, lemon oil and sandalwood can be used as perfume and scenting agents. Water and pentylene glycol were used as solvents. The aim of the invention is to develop a cream form with a pomade structure, which is formed by the combination of 7 different plant extracts and has restorative and healing properties. Petroleum derivatives such as petroleum jelly etc. One of the advantages of the product is that it does not use synthetic raw materials such as Another advantage is that natural preservatives are used and their effectiveness has been proven through tests. Thus, it is thought that the pomade-based cream, which can be prepared without harmful chemicals, has a natural structure, is environmentally friendly, and is thought to benefit the healing and repair of the skin that is irritated due to various environmental factors with the plants it contains, will be one of the most important product groups in the field of personal care and cosmetics. At the same time, the fact that the production process of the pomade-based cream content of the invention consists of short-term simple processes and the preferred packaging is environmentally friendly and recyclable aluminum tubes provides an advantage both for the production process and for the product obtained. It also shows that the product is a product aimed at protecting the environment. It has been observed that the product of the invention, which is suitable for use on the entire surface of the skin, surprisingly shows multiple effects such as restorative and healing, moisturizing, soothing, redness relieving, filling lines and crevices and antioxidant effects. Another advantage of the invention is that the product is created by integrating many organic components that have various benefits for skin health and various herbs that have been used in alternative medicine for many years. Since the product of the invention is prepared in the form of a naturally occurring product, its side effects on human health will be minimal compared to other creams. One of the most important advantages of our cream is that no chemicals are used in the naturally prepared pomade cream. In this way, the cream obtained with the invention will have a structure suitable for use in almost all age groups. Another purpose of the invention is; To contribute to alternative products in the cosmetics industry and to provide benefits by offering a new product option where people can find all the features they need in line with the importance they attach to skin health. By utilizing 7 types of plants, the positive effects of each plant are contained in a single concentration. Positive effects offered by plants; - It moisturizes the skin, softens it, protects the moisture barrier - It reduces irritation, soothes and heals the skin - It has significant relieving and therapeutic properties of wounds, scars and crevices - It removes redness on the skin - It plumps the lines and crevices formed on the skin - It has antioxidant properties. . Examples of the features of the invention, but not limited to the ones below, are given below: In the invention, the pomade-based cream formulation, which has a natural structure, repairing, healing and moisturizing effect on irritated skin, suitable for use on the whole body and for all age groups, prepared by using 7 types of plant extracts, is planned to contain the following: - 0.00001% by weight. -15 one or more skin healing, soothing and regulating substances - 0.01-7% by weight one or more astringent substances - 0.01-10% by weight one or more moisturizing substances - 0.001% by weight 20 one or more softening agents - 0.1-15% by weight one or more emulsifiers - 0.1-7% by weight one or more emulsion stabilizing agents - 0.0001-1% by weight one or more antioxidants - % by weight 0.00001-0.1% by weight one or more preservatives - 0.0001-0.1% by weight one or more buffering agents - 0.00001-0.1% by weight one or more perfume and scenting agents - 0.01-85% by weight one or more solvents. In the invention, the pomade-based cream formulation, prepared by using 7 types of plant extracts, with a natural structure, repairing, healing and moisturizing effect on irritated skin, suitable for use on the whole body and for all age groups, is characterized by containing the following: - 0.00001-15% by weight Madecassoside, shea butter (Bulyrospermum). parki'i'), soybean (Glyci'ne Soja) oil, calendula (Calendula Oyýfi'ci'nali's) flower extract, fructooligosaccharides, red beet (Beta Vulgari's) root extract, isopropyl benzyl salicylate and isodecyl salicylate, Vitamin F, chamomile (Chamomi'lla Recuti'ta) flower extract, rosemary (Rosmari'nus Oyýfi'ci'nali's) essential oil, lemon (Citrus limon) essential - 0.01-7% by weight witch hazel (Hamameli's Virginiana) leaf and okka rose (Rosa x Centi'foli'a) - 0.01-10% by weight glycerin - 0.001-20% by weight glyceryl caprylate/caprate, caprylic/capric triglyceride and lavender (Lavandula Hybrida) essential oil - 0.1-15% by weight glyceryl stearate, polyglyceryl- 3 rice branate, sucrose stearate, cetearyl alcohol, cetearyl olivate and sorbitan olivate - 0% by weight, 1-7 behenyl alcohol - 0.0001-1% by weight tocopherol - 0.00001-0.1% by weight sodium benzoate, potassium sorbate, phenoxyethanol, benzoic acid and dehydroacetic - 0.0001-0.1% by weight sodium hydroxide - 0.00001-0.1% by weight methyl eugenol and turmeric (Curcuma Longa) root extract - 0.01-85% by weight water and pentylene glycol. Production process: Components A are added to components B and mixed. Components C are added and mixing continues. Components D are added to the resulting mixture and mixed. Finally, E components are added and mixing continues and the final product is obtained. The ingredients mentioned here are as follows: B: Caprylic/Capric Triglyceride, Glyceryl Stearate, Polyglyceryl-3 Rice Branate, Cetearyl Alcohol, Sucrose Stearate, Behenyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, shea butter (Bulyrospermum parkii), Calendula (Calendula). Oficinalis) flower extract, Soybean (Glyci'ne Soja) oil, Tocopherol C: isopropyl benzyl salicylate and isodecyl salicylate D: Fructooligosaccharides, Red Beet (Beta Vulgari's) Root Extract, Turmeric (Curcuma Longa) Root Extract, Linoleic Acid, Linolenic Acid , Witch Hazel (Hamameli's Virginiana), Chamomile (Chamomi'lla Recutita) Flower Extract, Pentylene Glycol, Glyceryl Caprylate/Caprate E: Rosemary (Rosmarinus Oßicinalis) Essential Oil, Lemon (Citrus limon) Essential Oil, Lavender (Lavandula Hybrida) Essential Oil , Okka Rose (Rosa x Centi'foli'a), Sodium Hydroxide. Microbiology tests (Table 1), protective effectiveness (Challenge) tests (Table 2) and perfume-free test (Table 3) were applied in order to ensure that the resulting cream with natural ingredients had a sustainable structure and to prove that the content did not contain chemicals after stability tests were performed. With the data obtained, it was observed that the specified criteria for the targeted product were met and it was concluded that there was no problem in terms of the production and use of the product. Table 1. Microbiological Test Results Preliminary Microbiological Test of the Sample Result Method Limit Evaluation Domonas aeruginosa Search and Detection Not available ISO 22717 Not available Appropriate Table 2. Protective Effectiveness (Challenge) Test Inoculation Sample Count, Drop, ten (Cfu) cfu/g [Nx=C/(de)] Log [Rx=IgN0-IgNx] Table 3. Perfume Free Test Analyzes Results Compatibility Analysis Method Free of Synthetic Perfume Z Analysis cm'1 Not Detected DY In House Method (Infrared Spectrum) Additionally, dermatological tests were performed on 25 subjects and observed. According to the patch tests performed on the subject, it has been proven that the product does not have any irritating effects 0 It meets the requirements of the skin tolerance test 0 It meets the requirements of cosmetic products with declared human health safety features.TR TR TR
Claims (1)
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| Publication Number | Publication Date |
|---|---|
| TR2022007546A2 true TR2022007546A2 (en) | 2023-11-21 |
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