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TR200102493T2 - IgE'nin C-epsilon-3 veya C-epsilon-4 alanlarından türetilmiş epitoplar veya mimotoplar. - Google Patents

IgE'nin C-epsilon-3 veya C-epsilon-4 alanlarından türetilmiş epitoplar veya mimotoplar.

Info

Publication number
TR200102493T2
TR200102493T2 TR2001/02493T TR200102493T TR200102493T2 TR 200102493 T2 TR200102493 T2 TR 200102493T2 TR 2001/02493 T TR2001/02493 T TR 2001/02493T TR 200102493 T TR200102493 T TR 200102493T TR 200102493 T2 TR200102493 T2 TR 200102493T2
Authority
TR
Turkey
Prior art keywords
epsilon
ige
epitopes
domains
immunoprophylaxis
Prior art date
Application number
TR2001/02493T
Other languages
English (en)
Inventor
Friede Martin
Mason Sean
Gordon Turnell William
Paulette Van Mechelen Marcelle
Vinals Y De Bassols Carlota
Original Assignee
Smithkline Beecham Biologicals S.A.
Acambis Research Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9904408.3A external-priority patent/GB9904408D0/en
Priority claimed from GBGB9917144.9A external-priority patent/GB9917144D0/en
Priority claimed from GBGB9918604.1A external-priority patent/GB9918604D0/en
Priority claimed from GBGB9918601.7A external-priority patent/GB9918601D0/en
Priority claimed from GBGB9918598.5A external-priority patent/GB9918598D0/en
Priority claimed from GBGB9918606.6A external-priority patent/GB9918606D0/en
Priority claimed from GBGB9918599.3A external-priority patent/GB9918599D0/en
Priority claimed from GBGB9925618.2A external-priority patent/GB9925618D0/en
Application filed by Smithkline Beecham Biologicals S.A., Acambis Research Limited filed Critical Smithkline Beecham Biologicals S.A.
Publication of TR200102493T2 publication Critical patent/TR200102493T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Bu bulus alerjik hastaliklarin tedavisi, önlenmesi veya hafifletilmesine iliskin yeni ilaçlarin temini ile ilgilidir. Özellikle, bu yeni ilaçlar, IgE'nin C-espilon-3 veya C-epsilon-4 alanlarindan türetilen epitoplar veya mimotoplardir. Bu yeni bölgeler gerek pasif gerekse aktif immünoprofilaksi veya immünoterapi için hedef olusturabilirler. Bu bulus ayrica ilaçlarin, bunlari içeren farmasötik bilesimlerin üretimi ve bunlarin tipta kullanimina iliskin yöntemlerle de ilgilidir. Ayrica, bu bulus kapsamindaki IgE bölgelerine baglanma kabiliyetine sahip ligandlar, özellikle monoklonal antikorlar ve bunlarin pasif immünoterapi veya immünoprofilaksi olarak kullanilmasi bu bulusun bir baska yönünü olusturmaktadir.
TR2001/02493T 1999-02-25 2000-02-22 IgE'nin C-epsilon-3 veya C-epsilon-4 alanlarından türetilmiş epitoplar veya mimotoplar. TR200102493T2 (tr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GBGB9904408.3A GB9904408D0 (en) 1999-02-25 1999-02-25 Vaccine
GBGB9917144.9A GB9917144D0 (en) 1999-07-21 1999-07-21 Vaccine
GBGB9918604.1A GB9918604D0 (en) 1999-08-07 1999-08-07 Novel peptides
GBGB9918601.7A GB9918601D0 (en) 1999-08-07 1999-08-07 Novel peptides
GBGB9918598.5A GB9918598D0 (en) 1999-08-07 1999-08-07 Novel peptides
GBGB9918606.6A GB9918606D0 (en) 1999-08-07 1999-08-07 Novel peptides
GBGB9918599.3A GB9918599D0 (en) 1999-08-07 1999-08-07 Novel peptides
GBGB9925618.2A GB9925618D0 (en) 1999-10-29 1999-10-29 Vaccine

Publications (1)

Publication Number Publication Date
TR200102493T2 true TR200102493T2 (tr) 2002-02-21

Family

ID=27571340

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/02493T TR200102493T2 (tr) 1999-02-25 2000-02-22 IgE'nin C-epsilon-3 veya C-epsilon-4 alanlarından türetilmiş epitoplar veya mimotoplar.

Country Status (18)

Country Link
EP (1) EP1155038A1 (tr)
JP (1) JP2002537403A (tr)
KR (1) KR20020007314A (tr)
CN (1) CN1520423A (tr)
AR (1) AR029619A1 (tr)
AU (1) AU3281100A (tr)
CA (1) CA2363641A1 (tr)
CO (1) CO5231139A1 (tr)
CZ (1) CZ20013081A3 (tr)
HK (1) HK1043134A1 (tr)
HU (1) HUP0105490A3 (tr)
IL (1) IL145025A0 (tr)
MX (1) MXPA01008612A (tr)
NO (1) NO20014131L (tr)
NZ (1) NZ513680A (tr)
PL (1) PL350992A1 (tr)
TR (1) TR200102493T2 (tr)
WO (1) WO2000050461A1 (tr)

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WO2001045745A2 (en) * 1999-12-21 2001-06-28 Acambis Research Limited A reversible linkage technology for controlled conjugation
EP1278542A2 (en) 2000-05-05 2003-01-29 Cytos Biotechnology AG Molecular antigen arrays and vaccines
GB0026334D0 (en) * 2000-10-27 2000-12-13 Smithkline Beecham Biolog Vaccine
US7128911B2 (en) 2001-01-19 2006-10-31 Cytos Biotechnology Ag Antigen arrays for treatment of bone disease
US7094409B2 (en) 2001-01-19 2006-08-22 Cytos Biotechnology Ag Antigen arrays for treatment of allergic eosinophilic diseases
US7264810B2 (en) 2001-01-19 2007-09-04 Cytos Biotechnology Ag Molecular antigen array
JP2003047482A (ja) 2001-05-22 2003-02-18 Pfizer Prod Inc 非アナフィラキシー誘発性ＩｇＥワクチン
DE60234375D1 (de) 2001-09-14 2009-12-24 Cytos Biotechnology Ag VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG
US7115266B2 (en) 2001-10-05 2006-10-03 Cytos Biotechnology Ag Angiotensin peptide-carrier conjugates and uses thereof
GB0209878D0 (en) * 2002-04-30 2002-06-05 Glaxosmithkline Biolog Sa Vaccine
CN1668637B (zh) 2002-07-17 2010-05-26 希托斯生物技术股份公司 使用衍生自ap205外壳蛋白的病毒样颗粒的分子抗原阵列
KR20120041739A (ko) 2002-07-18 2012-05-02 사이토스 바이오테크놀로지 아게 합텐-캐리어 컨쥬게이트 및 그의 용도
DK1524994T3 (da) 2002-07-19 2011-08-15 Cytos Biotechnology Ag Vaccinesammensætninger indeholdende amyloid beta 1-6-antigen-arrays
US7537767B2 (en) 2003-03-26 2009-05-26 Cytis Biotechnology Ag Melan-A- carrier conjugates
JP5022028B2 (ja) 2003-03-26 2012-09-12 サイトス・バイオテクノロジー・アクチェンゲゼルシャフト メラン−ａペプチドアナログ−ウイルス様粒子コンジュゲート
CA2552999A1 (en) * 2004-02-02 2005-08-18 Tanox, Inc. Identification of novel ige epitopes
GB0424563D0 (en) 2004-11-05 2004-12-08 Novartis Ag Organic compounds
EP1941275B1 (en) 2005-09-29 2013-07-24 Medimmune, Inc. Method of identifying membrane lg specific antibodies and use thereof for targeting immunoglobulin-producing precursor cells
JP5484732B2 (ja) 2005-12-14 2014-05-07 サイトス バイオテクノロジー アーゲー 過敏症の治療のための免疫賦活性核酸パッケージ粒子
RU2476595C2 (ru) 2006-06-12 2013-02-27 Цитос Биотехнологи Аг Способы упаковки олигонуклеотидов в вирусоподобные частицы рнк-содержащих бактериофагов
EP2865389A1 (en) 2008-12-09 2015-04-29 Pfizer Vaccines LLC IgE CH3 peptide vaccine
CA2800774A1 (en) * 2010-06-07 2011-12-15 Pfizer Vaccines Llc Ige ch3 peptide vaccine
CN104395337A (zh) * 2012-06-18 2015-03-04 日本全药工业株式会社 IgE肽疫苗
WO2019194656A1 (ko) * 2018-04-06 2019-10-10 (주)에스엘에스바이오 신규한 면역글로불린 e의 에피토프, 그와 결합하는 항체 및 상기 항체를 포함하는 시료 중 면역글로불린 e를 분석하기 위한 키트
US20240245190A1 (en) 2023-01-19 2024-07-25 Sharkninja Operating Llc Identification of hair care appliance attachments
WO2024155914A1 (en) 2023-01-19 2024-07-25 Sharkninja Operating Llc Hair care appliance with powered attachment
WO2025100514A1 (ja) * 2023-11-09 2025-05-15 株式会社ファンペップ 抗ＩｇＥ抗体誘導用ワクチン組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02229200A (ja) * 1989-02-28 1990-09-11 Dainippon Pharmaceut Co Ltd 抗アレルギー作用を有するペプチド
DK0602126T3 (da) * 1991-08-14 2003-06-16 Genentech Inc Immunoglobulinvarianter til specifikke FC epsilon-receptorer
CN1174998C (zh) * 1996-03-01 2004-11-10 诺瓦提斯公司 用于预防和治疗过敏的肽免疫原
AU6532498A (en) * 1996-12-06 1998-06-29 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Inhibition of ige-mediated allergies by a human ige-derived oligopeptide
TWI227241B (en) * 1998-06-20 2005-02-01 United Biomedical Inc IgE-CH3 domain antigen peptide, peptide conjugate containing the same, and pharmaceutical composition for treating allergies containing the peptide conjugate

Also Published As

Publication number Publication date
PL350992A1 (en) 2003-02-24
HK1043134A1 (zh) 2002-09-06
WO2000050461A1 (en) 2000-08-31
IL145025A0 (en) 2002-06-30
CA2363641A1 (en) 2000-08-31
NO20014131D0 (no) 2001-08-24
AU3281100A (en) 2000-09-14
CN1520423A (zh) 2004-08-11
EP1155038A1 (en) 2001-11-21
AR029619A1 (es) 2003-07-10
KR20020007314A (ko) 2002-01-26
HUP0105490A3 (en) 2002-05-28
CO5231139A1 (es) 2002-12-27
NZ513680A (en) 2001-09-28
NO20014131L (no) 2001-10-02
HUP0105490A2 (hu) 2002-04-29
CZ20013081A3 (cs) 2002-02-13
MXPA01008612A (es) 2003-06-24
JP2002537403A (ja) 2002-11-05

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