TR200100452T1 - Aspirin applied through the skin - Google Patents
Aspirin applied through the skinInfo
- Publication number
- TR200100452T1 TR200100452T1 TR2001/00452T TR200100452T TR200100452T1 TR 200100452 T1 TR200100452 T1 TR 200100452T1 TR 2001/00452 T TR2001/00452 T TR 2001/00452T TR 200100452 T TR200100452 T TR 200100452T TR 200100452 T1 TR200100452 T1 TR 200100452T1
- Authority
- TR
- Turkey
- Prior art keywords
- skin
- aspirin
- application
- solution
- crumbled
- Prior art date
Links
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title abstract 5
- 229960001138 acetylsalicylic acid Drugs 0.000 title abstract 5
- 239000002904 solvent Substances 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 231100000344 non-irritating Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Deri yoluyla uygulamaya müsait bir aspirin formülasyonudur. Ufalanmis aspirin, farmakolojik olarak uygun olan bir solven ve organik amin'den olusan bir solusyon içinde oldukça yüksek konsantrasyonlarda çözülür. Primer solven, tercihen deriye uygulanmaya uygun özellikleri bulunan bir organik hidroksi bilesenidir. Sonuçta elde edilen aspirin deriyi tahris etmez nitelikte olup, deri yoluyla uygulama düzeneginde uzun süreli ve iyi bir stabilite sergiler. Aspirin solusyonunu deri yoluyla uygulamak için uygun bir düzenek ayrica açiklanmistir.It is an aspirin formulation suitable for administration via the skin. Crumbled aspirin is dissolved in very high concentrations in a solution consisting of a pharmacologically acceptable solvent and organic amine. The primary solvent is preferably an organic hydroxy component with properties suitable for application to the skin. The resulting aspirin is non-irritating to the skin and exhibits long-term and good stability in the skin-to-skin application device. A suitable device for applying aspirin solution through the skin has also been described.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32934999A | 1999-06-10 | 1999-06-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200100452T1 true TR200100452T1 (en) | 2001-07-23 |
Family
ID=23284975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/00452T TR200100452T1 (en) | 1999-06-10 | 1999-06-11 | Aspirin applied through the skin |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1104236A1 (en) |
| JP (1) | JP2003501447A (en) |
| KR (1) | KR20010072412A (en) |
| AU (1) | AU4552399A (en) |
| BR (1) | BR9912954A (en) |
| CA (1) | CA2340120A1 (en) |
| HU (1) | HUP0103110A3 (en) |
| IL (1) | IL141348A0 (en) |
| MX (1) | MXPA01001490A (en) |
| TR (1) | TR200100452T1 (en) |
| WO (1) | WO2000076315A1 (en) |
| ZA (1) | ZA200101153B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0103528D0 (en) | 2001-10-21 | 2001-10-21 | Jan Faergeman | Topical compositions with enhanced effect |
| WO2011076401A1 (en) | 2009-12-23 | 2011-06-30 | Holger Schankin | Substantially water-free pharmaceutical compositions containing acetylsalicylic acid |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4725590A (en) * | 1983-08-24 | 1988-02-16 | Lever Brothers Company | Method of relieving pain and inflammatory conditions employing substituted salicylamides |
-
1999
- 1999-06-11 CA CA002340120A patent/CA2340120A1/en not_active Abandoned
- 1999-06-11 TR TR2001/00452T patent/TR200100452T1/en unknown
- 1999-06-11 MX MXPA01001490A patent/MXPA01001490A/en unknown
- 1999-06-11 WO PCT/US1999/012793 patent/WO2000076315A1/en not_active Application Discontinuation
- 1999-06-11 AU AU45523/99A patent/AU4552399A/en not_active Abandoned
- 1999-06-11 KR KR1020017001792A patent/KR20010072412A/en not_active Withdrawn
- 1999-06-11 HU HU0103110A patent/HUP0103110A3/en unknown
- 1999-06-11 BR BR9912954-0A patent/BR9912954A/en not_active Application Discontinuation
- 1999-06-11 JP JP2001502672A patent/JP2003501447A/en active Pending
- 1999-06-11 EP EP99928460A patent/EP1104236A1/en not_active Withdrawn
- 1999-06-11 IL IL14134899A patent/IL141348A0/en unknown
-
2001
- 2001-02-09 ZA ZA200101153A patent/ZA200101153B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2340120A1 (en) | 2000-12-21 |
| EP1104236A1 (en) | 2001-06-06 |
| JP2003501447A (en) | 2003-01-14 |
| MXPA01001490A (en) | 2002-11-29 |
| WO2000076315A1 (en) | 2000-12-21 |
| ZA200101153B (en) | 2002-05-09 |
| HUP0103110A3 (en) | 2002-11-28 |
| HUP0103110A2 (en) | 2002-05-29 |
| AU4552399A (en) | 2001-01-02 |
| KR20010072412A (en) | 2001-07-31 |
| IL141348A0 (en) | 2002-03-10 |
| BR9912954A (en) | 2001-05-08 |
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