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TNSN08287A1 - 3,5-substituted piperidine compounds as renin inhibitors - Google Patents

3,5-substituted piperidine compounds as renin inhibitors

Info

Publication number
TNSN08287A1
TNSN08287A1 TNP2008000287A TNSN08287A TNSN08287A1 TN SN08287 A1 TNSN08287 A1 TN SN08287A1 TN P2008000287 A TNP2008000287 A TN P2008000287A TN SN08287 A TNSN08287 A TN SN08287A TN SN08287 A1 TNSN08287 A1 TN SN08287A1
Authority
TN
Tunisia
Prior art keywords
substituted piperidine
treatment
compound
renin
disease
Prior art date
Application number
TNP2008000287A
Inventor
Takeru Ehara
Philipp Grosche
Osamu Irie
Yuki Iwaki
Takanori Kanazawa
Shimpei Kawakami
Kazuhide Konishi
Muneto Mogi
Masaki Suzuki
Fumiaki Yokokawa
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2006/012581 external-priority patent/WO2007077005A1/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of TNSN08287A1 publication Critical patent/TNSN08287A1/en

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (= disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,5-substituted piperidine compound, a method for the manufacture of a 3, 5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. The preferred compounds (which can also be present as salts) have the formula (I'), wherein R1 , R2, T, R3 and R4 are as defined in the specification.
TNP2008000287A 2005-12-30 2008-06-27 3,5-substituted piperidine compounds as renin inhibitors TNSN08287A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05028771 2005-12-30
PCT/EP2006/012581 WO2007077005A1 (en) 2005-12-30 2006-12-28 3 , 5-substitγued piperidine compounds as renin inhibitors

Publications (1)

Publication Number Publication Date
TNSN08287A1 true TNSN08287A1 (en) 2009-10-30

Family

ID=40391423

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2008000287A TNSN08287A1 (en) 2005-12-30 2008-06-27 3,5-substituted piperidine compounds as renin inhibitors

Country Status (4)

Country Link
CN (1) CN101365680A (en)
TN (1) TNSN08287A1 (en)
UA (1) UA96282C2 (en)
ZA (1) ZA200804956B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015156346A1 (en) * 2014-04-10 2015-10-15 武田薬品工業株式会社 Method for producing heterocyclic compound
JP6832946B2 (en) * 2015-11-17 2021-02-24 アエリエ ファーマシューティカルズ インコーポレイテッド How to prepare kinase inhibitors and their intermediates
CN117865941B (en) * 2024-03-13 2024-06-28 上海方予健康医药科技有限公司 Substituted piperidine compounds, process for their preparation and their use

Also Published As

Publication number Publication date
UA96282C2 (en) 2011-10-25
ZA200804956B (en) 2009-05-27
CN101365680A (en) 2009-02-11

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