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TJ189R3 - Inclusion complexes of 3-morpholinesydnonimine or its salts, or its tautomeric isomer with cyclodextrine or its deri-vatives, method for preparation thereof, pharmaceutical composition thereof, methodfor preparation thereof and for treatment of sten ocardia or ishemic desease. - Google Patents

Inclusion complexes of 3-morpholinesydnonimine or its salts, or its tautomeric isomer with cyclodextrine or its deri-vatives, method for preparation thereof, pharmaceutical composition thereof, methodfor preparation thereof and for treatment of sten ocardia or ishemic desease.

Info

Publication number
TJ189R3
TJ189R3 TJ94000008A TJ94000008A TJ189R3 TJ 189 R3 TJ189 R3 TJ 189R3 TJ 94000008 A TJ94000008 A TJ 94000008A TJ 94000008 A TJ94000008 A TJ 94000008A TJ 189 R3 TJ189 R3 TJ 189R3
Authority
TJ
Tajikistan
Prior art keywords
preparation
salts
morpholinesydnonimine
ocardia
ishemic
Prior art date
Application number
TJ94000008A
Other languages
English (en)
Inventor
Maria Vikmon
Jozsef Szejtli
Lajos Szente
Jozsef Gaal
Istvan Hermecz
Agnes Horvath
Katalin Marmarosi
Gabor Horvath
Iren Munkacsi
Original Assignee
Therabel Ind Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therabel Ind Sa filed Critical Therabel Ind Sa
Publication of TJ189R3 publication Critical patent/TJ189R3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/04—1,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
TJ94000008A 1990-03-28 1994-11-28 Inclusion complexes of 3-morpholinesydnonimine or its salts, or its tautomeric isomer with cyclodextrine or its deri-vatives, method for preparation thereof, pharmaceutical composition thereof, methodfor preparation thereof and for treatment of sten ocardia or ishemic desease. TJ189R3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU901869A HU212730B (en) 1990-03-28 1990-03-28 Process for producing inclusion complexes of cyclodextrine or its derivative and 3-morpholino-sydnonimine or its salt or its tautomer and pharmaceutical compositions containing them
SU5010582A RU2107695C1 (ru) 1990-03-28 1991-03-28 Комплекс включения 3-морфолиносиднонимина или его соли, или его таутомерного изомера с циклодекстрином или производным циклодекстрина, способ его получения и содержащая его фармацевтическая композиция, способ получения фармацевтической композиции и способ лечения стенокардии и ишемической болезни человека
PCT/HU1991/000013 WO1991014681A1 (fr) 1990-03-28 1991-03-28 Complexes d'inclusion de 3-morpholino-sydnonimine ou de ses sels ou de son isomere tautomere, procede de preparation de tels complexes et compositions pharmaceutiques contenant de tels complexes

Publications (1)

Publication Number Publication Date
TJ189R3 true TJ189R3 (en) 1998-10-28

Family

ID=10956597

Family Applications (1)

Application Number Title Priority Date Filing Date
TJ94000008A TJ189R3 (en) 1990-03-28 1994-11-28 Inclusion complexes of 3-morpholinesydnonimine or its salts, or its tautomeric isomer with cyclodextrine or its deri-vatives, method for preparation thereof, pharmaceutical composition thereof, methodfor preparation thereof and for treatment of sten ocardia or ishemic desease.

Country Status (33)

Country Link
US (1) US5298496A (fr)
EP (1) EP0478732B1 (fr)
JP (1) JP2549961B2 (fr)
KR (1) KR950004706B1 (fr)
CN (1) CN1051081C (fr)
AT (1) ATE170849T1 (fr)
AU (1) AU635835B2 (fr)
BG (1) BG61812B1 (fr)
BR (1) BR9105137A (fr)
CA (1) CA2054213C (fr)
CZ (1) CZ285695B6 (fr)
DE (1) DE69130146T2 (fr)
DK (1) DK0478732T3 (fr)
ES (1) ES2121780T3 (fr)
FI (1) FI104882B (fr)
GE (1) GEP19991743B (fr)
HK (1) HK1011688A1 (fr)
HR (1) HRP920560B1 (fr)
HU (2) HU211648A9 (fr)
LT (1) LT3257B (fr)
LV (1) LV10087B (fr)
MC (1) MC2186A1 (fr)
MD (1) MD776C2 (fr)
MW (1) MW6891A1 (fr)
NO (1) NO303634B1 (fr)
OA (1) OA09522A (fr)
PL (1) PL165866B1 (fr)
RO (1) RO109336B1 (fr)
RU (1) RU2107695C1 (fr)
SI (1) SI9110909B (fr)
TJ (1) TJ189R3 (fr)
UA (1) UA27242C2 (fr)
WO (1) WO1991014681A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU210921B (en) * 1990-03-28 1995-09-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing inclusion complexes of n-ethoxycarbonyl-3-morpholino-sydnonimine formed with cyclodextrines and pharmaceutical compositions containing them
DE4117249C2 (de) * 1991-05-27 1998-05-14 Christian Dr Stief Linsidomin zur Behandlung erektiler Dysfunktionen
HU213200B (en) 1993-05-12 1997-03-28 Chinoin Gyogyszer Es Vegyeszet The cyclodextrin or cyclodextrin derivative cluster complexes of taxol, taxotere, or taxus, pharmaceutical preparations containing them and process for their production
HU218280B (en) * 1994-04-26 2000-07-28 Cyclodextrin inclusion complexes containing sin-1a which are stable intheir solid state, process for their preparation and pharmaceutical compositions containing the comlexes
GB9915231D0 (en) 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex
FR2805462B1 (fr) * 2000-02-24 2003-08-15 Therabel Res Nouvelle forme galenique orale a liberation prolongee de la molsidomine
ATE319480T1 (de) * 2000-05-11 2006-03-15 Eastman Chem Co Acylierte zyklodextrin guest-inklusion komplexe

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1496056A (fr) * 1964-06-08 1967-09-29 Takeda Chemical Industries Ltd Nouveaux composés chimiques du type sydnonimine
DE3221425A1 (de) * 1982-06-07 1983-12-08 Boehringer Ingelheim KG, 6507 Ingelheim Hydrolyseempfindlichen wirkstoff enthaltende, lagerstabile tablette
DE3346638A1 (de) * 1983-12-23 1985-07-04 Cassella Ag, 6000 Frankfurt Photostabilisierung von molsidomin
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
DE3522191A1 (de) * 1985-06-21 1987-01-15 Cassella Ag Photostabilisierung von sydnoniminen
GB8613688D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
JPH0819004B2 (ja) * 1986-12-26 1996-02-28 日清製粉株式会社 徐放性医薬製剤
IT1204725B (it) * 1987-06-17 1989-03-10 Edmond Pharma Srl Complessi di inclusione del dipiridamolo con ciclodestrine
SE8904296D0 (sv) * 1989-12-21 1989-12-21 Pharmacia Ab Transdermal system
WO1991015346A1 (fr) * 1990-04-06 1991-10-17 Gerhard Blatt Installation servant au conditionnement de blocs de beton

Also Published As

Publication number Publication date
MD940334A (en) 1996-10-31
DE69130146T2 (de) 1999-04-01
MC2186A1 (fr) 1992-09-16
CZ85291A3 (en) 1993-11-17
ES2121780T3 (es) 1998-12-16
JPH04506221A (ja) 1992-10-29
FI915570A0 (fi) 1991-11-26
NO303634B1 (no) 1998-08-10
NO914650D0 (no) 1991-11-27
US5298496A (en) 1994-03-29
DE69130146D1 (de) 1998-10-15
RU2107695C1 (ru) 1998-03-27
PL165866B1 (pl) 1995-02-28
BR9105137A (pt) 1992-08-04
HU211648A9 (en) 1995-12-28
RO109336B1 (ro) 1995-01-30
MW6891A1 (en) 1993-07-14
CA2054213C (fr) 1998-12-01
SI9110909A (sl) 1998-06-30
UA27242C2 (uk) 2000-08-15
AU635835B2 (en) 1993-04-01
HRP920560B1 (en) 1999-12-31
DK0478732T3 (da) 1999-06-07
FI104882B (fi) 2000-04-28
LV10087B (en) 1995-02-20
HK1011688A1 (en) 1999-07-16
KR920701183A (ko) 1992-08-11
HU901869D0 (en) 1990-07-28
CN1051081C (zh) 2000-04-05
EP0478732A1 (fr) 1992-04-08
NO914650L (no) 1991-11-27
JP2549961B2 (ja) 1996-10-30
HRP920560A2 (hr) 1994-04-30
HU212730B (en) 1996-10-28
MD776C2 (ro) 1998-05-31
GEP19991743B (en) 1999-09-10
OA09522A (en) 1992-11-15
CN1055928A (zh) 1991-11-06
KR950004706B1 (ko) 1995-05-04
PL293020A1 (en) 1992-12-28
CZ285695B6 (cs) 1999-10-13
WO1991014681A1 (fr) 1991-10-03
SI9110909B (sl) 1999-02-28
ATE170849T1 (de) 1998-09-15
BG61812B1 (bg) 1998-06-30
HUT58110A (en) 1992-01-28
EP0478732B1 (fr) 1998-09-09
LTIP387A (en) 1994-09-25
BG95530A (bg) 1993-12-24
CA2054213A1 (fr) 1991-09-29
LV10087A (lv) 1994-05-10
LT3257B (en) 1995-05-25
MD776B2 (en) 1997-07-31
AU7549391A (en) 1991-10-21

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