TH141010A - Production process of pro new lights - Google Patents
Production process of pro new lightsInfo
- Publication number
- TH141010A TH141010A TH1301000202A TH1301000202A TH141010A TH 141010 A TH141010 A TH 141010A TH 1301000202 A TH1301000202 A TH 1301000202A TH 1301000202 A TH1301000202 A TH 1301000202A TH 141010 A TH141010 A TH 141010A
- Authority
- TH
- Thailand
- Prior art keywords
- trifluoromethylphenyl
- cyano
- amino
- dichloro
- pyrazole
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- -1 Trifluoromethylphenyl Chemical group 0.000 claims abstract 6
- 238000000034 method Methods 0.000 claims abstract 6
- ZOCSXAVNDGMNBV-UHFFFAOYSA-N Fipronil Chemical compound NC1=C(S(=O)C(F)(F)F)C(C#N)=NN1C1=C(Cl)C=C(C(F)(F)F)C=C1Cl ZOCSXAVNDGMNBV-UHFFFAOYSA-N 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drugs Drugs 0.000 claims abstract 2
- 239000005899 Fipronil Substances 0.000 claims 1
- 229940013764 fipronil Drugs 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- MHAJPDPJQMAIIY-UHFFFAOYSA-N hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 6
- 239000002253 acid Substances 0.000 abstract 4
- JXTHNDFMNIQAHM-UHFFFAOYSA-N Dichloroacetic acid Chemical compound OC(=O)C(Cl)Cl JXTHNDFMNIQAHM-UHFFFAOYSA-N 0.000 abstract 2
- 229960005215 dichloroacetic acid Drugs 0.000 abstract 2
- 230000003647 oxidation Effects 0.000 abstract 2
- 238000007254 oxidation reaction Methods 0.000 abstract 2
- QACJNLFCDPDUNE-UHFFFAOYSA-N 2-[[4-(carboxymethylamino)-6-chloro-1,3,5-triazin-2-yl]amino]acetic acid Chemical compound OC(=O)CNC1=NC(Cl)=NC(NCC(O)=O)=N1 QACJNLFCDPDUNE-UHFFFAOYSA-N 0.000 abstract 1
- FOCAUTSVDIKZOP-UHFFFAOYSA-N Chloroacetic acid Chemical compound OC(=O)CCl FOCAUTSVDIKZOP-UHFFFAOYSA-N 0.000 abstract 1
- FQXWEKADCSXYOC-UHFFFAOYSA-N fipronil-sulfide Chemical compound NC1=C(SC(F)(F)F)C(C#N)=NN1C1=C(Cl)C=C(C(F)(F)F)C=C1Cl FQXWEKADCSXYOC-UHFFFAOYSA-N 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Abstract
DC60 (11/04/56) กระบวนการออกซิเดชั่น (oxidation process) ที่ผ่านการปรับปรุงเพื่อการเตรียม 5-อะมิโน- 3- ไซยาโน-1-(2,6- ไดคลอโร-4-ไตรฟลูออโรเมทิลฟีนิล)-4-ไตรฟลูออโรเมทิลซัลไฟนีล-ไพราโซล [5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulphinyl- pyrazole] ของสูตร (I) นำมาอธิบาย โดยกระบวนการนี้ครอบคลุมถึงการผสม 5-อะมิโน-3-ไซยา โน -1-(2,6-ไดคลอโร-4-ไตรฟลูออโรเมทิลฟีนิล )-4-ไตรฟลูออโรเมทิลธิโอไพราโซล [5-amino-3- cyano-1-(2,6-dichloro-4- trifluoromethylphenyl)-4-trifluoromethylthiopyrazole] ของสูตร (II) กับ กรดไดคลอโรแอซีติก (dichloroacetic acid) กับ ไฮโดรเจน เปอร์ออกไซด์ (hydrogen peroxide) ใน ที่ๆมีกรดแก่ (strong acid) กระบวนการออกซิเดชั้น (oxidation process) ที่ผ่านการปรับปรุงเพื่อการเตรียม 5- อะมิโน -3- ไซยาโน -1-(2,6- ไดคลอโร-4- ไตรฟลูออโรเมทิลฟีนิล )-4- ไตรฟลูออโรเมทิลซัลโฟนีล -ไพราโซล [5- amino-3- cyano-1-(2,6- dichloro-4- trifluoromethylphenyl)-4-tifluoromethylsulphinyl-pyrazole] ของสูตร (I) นำมาอธิบาย โดยกระบวนการนี้ครอบคลุมถึงการผสม 5- อะมิโน -3- ไซยา โน -1-(2,6- ไดคลอโร-4- ไตรฟลูออโรเมทิลฟีนิล )-4- ไตรฟลูออโรเมทิลธิโอไพราโซล [5- amino-3- cyano-1-(2,6- dichloro-4- trifluoromethylphenyl)-4- trifluoromethylsulphinyl ของสูตร (II) กับกรดไดคลอโรแอซีติก (dichlorocacetic acid) กับ ไฮโดรเจน เปอร์ออกไซด์ (hydrogen peroxide) ใน ที่ ๆ มีกรดแก่ (strong acid) สิทธิบัตรยา DC60 (11/04/13) modified oxidation process for the preparation of 5-amino-3-cyano-1- (2,6-dichloro-4-) Trifluoromethylphenyl) -4-trifluoromethylsulfonyl-pyrazole The [5-amino-3-cyano-1- (2,6-dichloro-4-trifluoromethylphenyl) -4-trifluoromethylsulphinyl- pyrazole] of the (I) formula is described by this process covering the compounding. 5-amino-3-cyano-1- (2,6-dichloro-4-trifluoromethylphenyl ) -4-trifluoromethylthiopyrazole [5-amino-3- cyano-1- (2,6-dichloro-4- trifluoromethylphenyl) -4-trifluoromethylthiopyrazole] of the (II) formulation with diacetic acid. Chloroacetic (dichloroacetic acid) with hydrogen peroxide in the presence of strong acid, oxidation process, modified for the preparation of 5-amino-3-cyano-1. - (2,6-dichloro-4-trifluoromethylphenyl) -4-trifluoromethylsulfonyl-pyrazole (5- amino-3- cyano-1- (2,6- dichloro-4- trifluoromethylphenyl) -4-tifluoromethylsulphinyl-pyrazole) of the (I) formula is described by this process covering the 5--amino-3-cyano-1- (2, 6-dichloro-4-trifluoromethylphenyl) -4-trifluoromethylthiopyrazol [5- amino-3- cyano-1- (2,6- dichloro-4 - trifluoromethylphenyl) -4- trifluoromethylsulphinyl of formula (II) with dichloroacetic acid. (dichlorocacetic acid) and hydrogen peroxide (hydrogen peroxide) in the presence of strong acid (strong acid) patent drug
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH141010A true TH141010A (en) | 2015-06-12 |
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