SU679583A1 - Method of obtaining derivatives of phenothiazine - Google Patents
Method of obtaining derivatives of phenothiazineInfo
- Publication number
- SU679583A1 SU679583A1 SU772500480A SU2500480A SU679583A1 SU 679583 A1 SU679583 A1 SU 679583A1 SU 772500480 A SU772500480 A SU 772500480A SU 2500480 A SU2500480 A SU 2500480A SU 679583 A1 SU679583 A1 SU 679583A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- phenothiazine
- obtaining derivatives
- phthalylphenothiazines
- derivatives
- obtaining
- Prior art date
Links
Landscapes
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Description
(54) СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ ФЕНОТИАЗИНА(54) METHOD FOR OBTAINING DERIVATIVES OF PHENOTHIAZINE
-фталилфенотиазины с высоким выходом .-phthalylphenothiazines with high yield.
Насто щий способ позвол ет избежать применени труднодоступных и довитых 2-аминотиофенолов, сократить врем проведени процесса, упростить технологию получени целевых продуктов, расширить сырьевую базу.The present method makes it possible to avoid the use of hard-to-reach and poisoned 2-aminothiophenols, to reduce the time of the process, to simplify the technology for the production of target products, to expand the raw material base.
Состав и строение полученных 7-окси-5 ,б-фталилфенотиазинов установлен с помощью элементного анализа и физико-химических методов. Кроме того, 7-ОКСИ-5,б-фталилфенотиазин бьол синтезирован известным методом и оказалс идентичным полученному по насто щему способу.The composition and structure of the obtained 7-hydroxy-5, b-phthalylphenothiazines was established using elemental analysis and physicochemical methods. In addition, 7-OXY-5, b-phthalylphenothiazine biol was synthesized by a known method and turned out to be identical to that obtained by the present method.
3,45 г (0,01 мол ) 3-фенилтиоантра- (1,9-cd)-изоксазолона-б выдер;«ивают в 120 мл кип щего диметилформамида 20 мин. Из охлажденной до комнатной температуры реакционной массы фильтрованием и промывкой осадка на фильтре этанолом (50 мл) выдел ют3.45 g (0.01 mol) of 3-phenylthioanthra- (1,9-cd) -isoxazolone-b are boiled; “they are put into 120 ml of boiling dimethylformamide for 20 minutes. From the reaction mixture cooled to room temperature, filtration and washing the filter cake with ethanol (50 ml) was isolated
7-ОКСИ-5,б-фталилфенотиазин. Выход 3,2 г (93%) . Т.пл. 264°С.7-OXY-5, b-phthalylphenothiazine. Yield 3.2 g (93%). M.p. 264 ° C.
Найдено, %: N 3,98; 4,06.Found,%: N 3.98; 4.06.
Вычислено, %: N 4,06.Calculated,%: N 4.06.
Синтез остальных 7-окси-5,б-фталилфенотиазинов проводитс совершенно аналогично. Характеристики полученных соединений приведены в таблице .The synthesis of the remaining 7-hydroxy-5, b-phthalylphenothiazines is carried out in exactly the same way. Characteristics of the compounds obtained are shown in the table.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU772500480A SU679583A1 (en) | 1977-06-20 | 1977-06-20 | Method of obtaining derivatives of phenothiazine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU772500480A SU679583A1 (en) | 1977-06-20 | 1977-06-20 | Method of obtaining derivatives of phenothiazine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU679583A1 true SU679583A1 (en) | 1979-08-15 |
Family
ID=20715074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU772500480A SU679583A1 (en) | 1977-06-20 | 1977-06-20 | Method of obtaining derivatives of phenothiazine |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU679583A1 (en) |
-
1977
- 1977-06-20 SU SU772500480A patent/SU679583A1/en active
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