SU465202A1 - The method of obtaining cholagogue stachiren - Google Patents
The method of obtaining cholagogue stachirenInfo
- Publication number
- SU465202A1 SU465202A1 SU1244221A SU1244221A SU465202A1 SU 465202 A1 SU465202 A1 SU 465202A1 SU 1244221 A SU1244221 A SU 1244221A SU 1244221 A SU1244221 A SU 1244221A SU 465202 A1 SU465202 A1 SU 465202A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- stachiren
- cholagogue
- obtaining
- dried
- chloroform
- Prior art date
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Description
1one
Изобретение относитс к фармацевтической промышленности, а именно к получению лекарственных препаратов.The invention relates to the pharmaceutical industry, namely the production of drugs.
Дл получени желчегонного средства траву чистеца, пр мого Slachys recta L экстрагируют смесью хлороформа и этилового спирта и после упаривани обрабатывают непол рным органическим растворителем, например эфиром, высушивают.To obtain a choleretic agent, the grass of the Purebred, direct Slachys recta L is extracted with a mixture of chloroform and ethyl alcohol and, after evaporation, treated with a non-polar organic solvent, for example ether, and dried.
Сырьем дл получени стахирена служит высушенна и обмолоченна трава чистеца пр мого, состо ща из смеси тонких стеблей, листьев, соцветий и отдельных цветков, частично бутонов и плодов.The raw material for the production of stachyrene is dried and threshed grass of Chistav straight, consisting of a mixture of thin stems, leaves, inflorescences and individual flowers, partly buds and fruits.
Способ получени стахирена осуш,ествл ют следуюш.им образом.The method for the preparation of stachyren is dried as follows.
Измельченную траву чистеца пр мого трижды экстрагируют смесью хлороформа и этилового спирта (3: 1), остаток сырь отжимают и объединенные извлечени после фильтровани упаривают до полного удалени хлороформа. Из полученного концентрата стахирен выдел ют с помош,ью непол рного органического растворител (эфира). Выпавший желтый осадок отдел ют, затем очищают промыванием органическим растворителем (эфиром , хлороформом) и сушат при температуре 25-35С. Выход препарата стахирена 5- 5,5%.Ground cleaned grass is extracted three times with a mixture of chloroform and ethyl alcohol (3: 1), the residue is drained and the combined extracts are filtered off after filtration until chloroform is completely removed. From the resulting concentrate, stachiren is isolated by the aid of a non-polar organic solvent (ether). The precipitated yellow precipitate is separated, then purified by washing with an organic solvent (ether, chloroform) and dried at 25-35 ° C. The yield of the drug stachiren 5-5.5%.
Стахирен оказывает достаточно эффективпое терапевтическое действие при лечении хронических заболеваний желчных нутей, обладает отчетливым холеристическим и противовоспалительным действием. Стахирен примен ют в виде таблеток в дозе 0,1-0,2 г. Переносимость препарата хороша , побочных влений не наблюдаетс .Stachyrene has a rather effective therapeutic effect in the treatment of chronic diseases of biliary chickpeas, has a distinct choleric and anti-inflammatory effect. Stachyrene is used in the form of tablets at a dose of 0.1-0.2 g. The tolerability of the drug is good, no adverse effects are observed.
Предмет изобретени Subject invention
Способ получени желчегонного средства, отличающийс тем, что траву чистеца пр мого Stachys recta L экстрагируют смесью хлороформа и этилового спирта и носле упаривани , обрабатывают непол рным органическим растворителем , например эфиром, высушивают.A method for preparing a choleretic agent, characterized in that the cleanest grass of direct Stachys recta L is extracted with a mixture of chloroform and ethyl alcohol and, after evaporation, treated with a non-polar organic solvent, for example ether, is dried.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU1244221A SU465202A1 (en) | 1968-05-28 | 1968-05-28 | The method of obtaining cholagogue stachiren |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU1244221A SU465202A1 (en) | 1968-05-28 | 1968-05-28 | The method of obtaining cholagogue stachiren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU465202A1 true SU465202A1 (en) | 1975-03-30 |
Family
ID=20442576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1244221A SU465202A1 (en) | 1968-05-28 | 1968-05-28 | The method of obtaining cholagogue stachiren |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU465202A1 (en) |
-
1968
- 1968-05-28 SU SU1244221A patent/SU465202A1/en active
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