SU1458844A1 - Apparatus for automated analysis of biological specimens - Google Patents

Abstract

The invention relates to medical technology. To shorten the analysis time by carrying out it directly on the filters without suspending and dissolving the precipitated sample, the device comprises a detection chamber 1, a dispenser 7, a filtration unit 4 and a vacuum pump 8. The filtration unit 4 is movable and consists of a cuvette 9 and an optically transparent material mounted on a solid substrate 11. The filtration unit 4 is connected to a vacuum pump 8 and is made thermostatically. Each of the cuvettes has the ability to move between the photomultipliers 2 by means of the drive 5. The sample radioactivity is recorded by a counting unit 3. 2 sludge. (L

Description

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The invention relates to a medical technique, namely, to measuring means for the study of environmental samples, and can be used to study the physio-chemical properties of cellular structures.

The purpose of the invention is to reduce the analysis time by performing the analysis directly on the filters without suspending and dissolving the precipitated sample.

Fig. 1 is a block diagram of a device for automated analysis of biological samples; in FIG. 2, a filtering unit.

The device contains a de-tecting camera 1 with photomultipliers 2 and a counting unit 3 located on it. Inside the detection chamber 1, a filtering unit 4 is installed that can be moved along the rollers by means of an electromechanical drive 5 controlled by the programmable unit 6. In addition, the programmable unit 6 controls the dispenser 7 and the vacuum pump 8; The filtering unit 4 consists of a cuvette in the form of hollow cylinders 9 made of optically transparent material with a JI 10 cover mounted on a solid substrate 11 with replaceable filters 12. Each From the cuvette it is possible to move between the photomultipliers 2 by means of the drive 5, the cuvette through a solid substrate 11 and the drain channels 13, equipped with shut-off valves 14 and a common collector 15, connected to a vacuum pump 8, the cuvettes are separated from each other by partition walls 16

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The device works as follows.

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Replaceable filters 12 are installed on the solid substrates 11 of the filtration unit 4, which are rigidly fixed in the horizontal plane on the solid substrates due to the tight fit of the hollow billers 9,

The sewage channels 13 are closed with stop valves 14. Using the dispenser 7, all components are supplied to the cuvettes (biological sample, appropriate solutions in a radioactive label) to prepare a radioactive biorevalent

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the environmental sample according to a specific program, which is set using programming unit 6. Then the sample is incubated with a radioactive label and appropriate solutions in a certain temperature mode. The radioactive label not included in the sample is removed by filtration. To do this, open the shut-off valves 14, turn on the pump 8 and filter the solution. In this case, the radioactive label that is not included passes through replaceable filters 12, and the radioactive biological photobiode is fixed on the filters, I

Next, an analysis of a radioactive biological sample is performed. For this, directly to the fixed

0, on a replaceable filter 12, a radioactive biological sample is supplied by the dispenser 7, the liquid scintillator is closed when the shut-off valves 14 are closed. mi 2, the radioactivity of the sample is recorded by the counting unit 3 as pulses per unit of time.

The use of the device allows to increase the accuracy and speed up the performance of radioactive analysis,

since the analysis is carried out directly on the filters without suspending and dissolving the precipitated sample, it is extracted from

0 filtering and transferring it to the detecting unit, thus avoiding quenching and loss of a part of the sample due to incomplete dissolution and partial precipitation at the bottom of the cuvette and

5 walls of tubes.

Claims (1)

Invention Formula A device for automated Q analysis of biological samples, comprising a detection chamber, a dispenser, a filtration unit and a vacuum pump, characterized in that, in order to reduce the analysis time, it is equipped with drain channels with shut-off valves, photomultipliers located on the detection chamber, and an electromechanical drive , with the filtering unit with U5884A. H It consists of a cuvette, each of which moves between the photomultipliers in the form of a hollow cylinder made of bodies by means of an actuator, and each optically transparent material from the cuvette is connected through drainage channels with replaceable filters and is possible with a vacuum pump.