SU1454478A1 - Apparatus for separation and treatment of blood - Google Patents

Abstract

The invention relates to medical technology and is intended to fractionate the blood of a donor or a patient into components with the possibility of removing (apheresis) one or more components. The purpose of the invention is to increase the safety during perfusion and the accuracy of controlling the ratio of components.

Description

W

kpoBH. The device contains a j: centrifuge unit of 15 pumps, each of which is connected to a speed sensor 17, and a power amplifier 18, an adjustment unit 16 equipped with a MS processor 25, two splitters Ne 26 and 27 frequencies and programmable counters 19-23, clock inputs of which are connected to the microprocessor 25 clock output directly, allowing inputs through the first frequency healer 26, and the outputs of power amplifiers 18 are connected to the outputs of the counters 19-23, to the clock of the counter from the multiplexer

24 are connected to the outputs of speed sensors 17, and the output of the second frequency divider 27 is connected to its permitting input, to the input of which the output of the first frequency divider 26 is connected, the control input of multiplexer 24 is connected to the control output of the microprocessor 25, the output of flow sensor 7 is connected to one input the microprocessor 25, the output of the second frequency divider 27 - to another input of the latter, and the counters 19-23 are connected to the microprocessor 25 via the interface bus. 1 l-ffl.

I

The invention relates to medical technology and is intended to fractionate the blood of a donor or patient into components in order to remove one or more components.

The purpose of the invention is to increase the safety during perfusion and the accuracy of controlling the ratio of blood components.

I The drawing is a functional diagram of a device for the separation and processing of blood. I The unit 1 for connecting the device to the patient or donor is connected via the supply line 2 to the blood supply unit triple 3, which is connected to the tank 4 for the anticoagulant. The feed of the latter into the tee 3 wasp / tdegenerated by the horn 5 by means of the pump 6 of the feed | anticoagulant. A flow sensor 7 is connected to line 2, which is connected to a centrifuge 8 intended to separate blood into major components.

The output components of osuttsest-. is as follows: plasma through line 9 using pump 10; erythrocytes - on line 11 using a pump 12; the leukoverzweis - along the highway 13 with the help of the pump 14. Each; The first of the electric drives of the pumping unit 1.5 is connected to the control unit 16 and contains a speed sensor 17 and a power sensor 18,

The control unit 16 consists of five programmable counters 19-23 operating in the standby multivibrator mode, a multiplexer 24, a microprocessor 25, and two dividers 26 and 27 of the clock frequency of the microprocessor. Counters 19-23 are connected by interface bus 28 to microprocessor 25.

A device for the separation and processing of blood works as follows.

Unit 1 is connected to a donor or patient. Depending on the task to be solved, a certain ratio K to blood-anticoagulant is selected, which during the operation should remain unchanged:

Q.2 -, Qfl

(ABOUT

where Q ,, p is the volume of blood taken from

donor (patient); Q. is the volume of anticoagulant supplied to the blood by pump 6, i.e. anti-coagul. feed pump performance.

The main condition for the normal operation of the system is equality with the supply T1-Schkosti supply to the centrifuge 8 and the total produce.: 1 1 pumps 10, 12, 14 pumps for the selection of the right blood components, i.e.

35

Iq

PdDoChes

, (2)

or. which is the same:

cr

+ Qfl Qg Q

t / l

(3)

where qr

Q.

Q

t / l

plasma extraction pump performance; red blood cell selection pump performance; platelet and leukocyte collection pump performance.

From this expression, taking into account expression (1), it is possible to derive the dependence of the anticoagulant feed pump capacity on a given K-blood-coagulant ratio and the performance of the selection pumps of the divided blood components.

 .

k + 1

(four)

After setting the 25 k ratios to the blood-coagulant from the microprocessor field, the necessary for this patient or donor performance of the pumps for the selection of the divided components Q are set

L

and Q

t / l

at the same time, the capacity of the anticoagulant feed pump Q is set automatically in accordance with expression (4),

When the system from sensors 17 to the outputs of the multiplexer 24 receives voltage pulses, the frequency of which is proportional to the rotational speed of the pumps 6, 10, 12, 14. The multiplexer on the commands of the microprocessor 25, coming through the bus 28, connects to the input T of the counter 23 alternately sensors 17. Counter 23 for a period of frequency Gs produces a pulse count coming from the currently connected sensor. The result of this counting via the interface bus 28 enters the microprocessor 25, which compares the received information corresponding to the current value of capacity with the given value of the performance of this pump. In the event that the current value of the pump capacity does not match the set value, the number recorded in the corresponding programmable counter 19-22 is corrected according to the selected control law.

From the outputs of counters 19-22, control signals in the form of pulse width modulated i. with the frequency of following the PG come to the inputs of the respective power amplifiers 18. The duty cycle of the pulses t determines the frequency of rotation of the electric drives of the pump unit 15, proportional to

pump performance b, 10, 12, 14, and in turn depends on the contents of the counters 19-22.

If the blood flow from the donor or the patient is too intense, i.e.

if the condition (2) is violated, the flow sensor 7 triggers, the signal from which enters the microprocessor 25. Upon receipt of the signal from the flow sensor 7, the microprocessor

gradually begins to reduce the performance of pumps 6, 10, 12, 14 so that the ratio of blood volume to volume of anticoagulant remains unchanged. A decrease in pump performance occurs until information is received from flow sensor 7 that equality (2) has been restored.

Claims (1)

30 claims A device for the separation and processing of blood, comprising a pump unit connected to a centrifuge, each of which is connected to a speed sensor and a power amplifier, a flow sensor and a control unit, the outputs of which are connected to the inputs of the respective power amplifiers, tl and Q enhancing the safety of perfusion and the accuracy of controlling the ratio of blood components; the control unit consists of a multiplex, a first and second frequency dividers, a microprocessor, and n + 1 programmable counters, where n is the number of outputs of the control unit, and the clock inputs and counters are connected to the clock output of the microprocessor, and the enabling inputs through the first frequency divider to one output of the microprocessor, the inputs of the power amplifiers are connected to the outputs of the n counters, and the outputs of the speed sensors through A multiplexer is connected to a clock input of a n + 1 counter, the enabling input of which is connected to the output of the second frequency divider, whose input is co5 51454478 diien with the output of the first dividers hour-rub, and the other input of the microprocessor the control input multiplex is connected to the output of the second divider Pa connected to the control output frequency, and the information inputs of all the microprocessor, the output of the flow sensor g meters are connected to the microprocess connected to one input by the microprocessor through the interface cable.