SU1438792A1 - Medicine for treatment of parodontosis - Google Patents

Description

(20 3410018/28-U (22) 12.01 „82 (46) 23.11.88. Bull. I 43

(71) All-Union Scientific Research Institute of Medical Technology (SU) and Research and Production Center for Special Polymers (VSg)

(72) A.Ya.Akimova, A.B.Davydov, G.M.Derkach, M.K., Dobrovolska, V.Limohina, G.S.Chuchmay (SU), V.Kabaivanov, P.Novakov, D. Kotsev and L. Dicheva (Bd)

(53) 615.45 (088.8) (56) Barabash R.D. and others. Brief theses of the Y Congress of Dentists of the Ukrainian SSR. - Odessa, 1978, p. 99-101,

(54) MEANS FOR THE TREATMENT OF PARADONTOSIS

(57) The invention relates to medicine. The agent contains, wt%: dioxidine 24-40, ethyl 5-cyanoacrylate 20-33, butyl C-cyanacrylate 20-33, and orotic acid microencapsulated in polyvinylpyrrolidine, 10-20. To prepare the agent, dioxidine and orotic acid are mixed, microcapsule bath in polyvinyl pyrrolidone, then ethyl- and butyl-Of-cyan acryl at. The resulting mass is applied to the wound surface in a continuous layer. The remedy shortens the treatment time by 1.5-2 Pa.

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This invention relates to medicine, in particular to dentistry.

The purpose of the invention is the cs / period of treatment.

Example 1, B-th L, 25 years old, Dnagkoe; Parodontosis of the degree After removal of dental plaque and surgical treatment of pathological periodontal pocket, the gum surface was isolated with cotton rollers, treated with a 5% solution of first-cm hydrogen and thoroughly dried with a dry tampon. In a container 7: for mixing the components, a caves, a single O, 15 g and containing 0.09 g (30 wt.%) Dioxidine and 0.06 g (20 wt.%) Orotic acid, microcled in polyvirpyrrolidone, were placed; A polyethylene syringe tube was added to a sample of O, 5 g (50 mAd, 15 drops) of a liquid base, containing ethyl ethyl-1-cyanoacrylate and butyl-C (-cyanoacr in a ratio of 1 :. Comp- I whizzed with a spatula, and the resulting

Ngznosili's paste on a wound surface with a continuous uniform layer of the Tolodan OjS-mm. After 3 mn, the composition is cured. The dressing remained in the oral cavity for 5 days. Repeated imposition of the composition was not carried out. The use of the composition led to the normalization and coloring of the gums, cessation of serous-purulent exudation from clinical pockets, the disappearance of edema and bleeding of the gums. Clinical tests normalized; Schiller-Pisarev test, the time of formation of vacuum hematomas, periodontal and hygienic indices.

PRI me R 2, With ,, 40 years, Diagnosis: periodontal disease III degree. The treatment of the teeth and the gums 1-1 .1 was carried out as in Example I. In the tank, the mixing plate of the components assayed a weight equal to 0.1 g 5 containing 0.07 g (24 wt.%) Dioxidine to 0.03 g (10 wt. .%) orotic acid microcapsulated in polyvincrypyrrolidone. From a polyethylene jugicep tube, a g (66 wt.%, 19 drops) liquid base containing ethyl-o (β-cyanoacrylate and butyl-0 (β-pianacrylate in the ratio of I: C) was added to the batch. and applied on the wound surface in a uniform layer, the interdisal gaps were left open in the outflow of exudate.

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curing KONmo3HHHH, After 3 days, re-applying the mixtures of the prophylactic system was performed using the same procedure. The double overlap of the coaxial lesion resulted in healing of the PG on the wound surface by primary tension, Adverse effects and pronounced local or general reactions were not identified, Clinical tests were normal and 3 o in a l s,

PRI and Ner 3. Bnl U ,, 38 years, / Diagnosis: periodontal disease of IT degree. Treatment of teeth and gums was performed as in examples 1 and 2. In the container for mixing the components was placed a weight equal to 0.15 g, containing 0.1 g (40 mAd) of dioxidine and 0.05 g of 20 Mac. j j orotic acid, microcapsulated in polyvinylpyrrolidone. From a polyethylene syringe tube, 0.1 g (40 fac,%, 10 drops) of a liquid base containing ethyl-0 (Cyanacrylate and butyl-cyapiacrylate I ratio) was added to the batch (mixture I ;, the composition was mixed and applied to the wound surface in continuous in a uniform layer. Repeatedly, the composition was not carried out. The use of the composition led to the elimination of the inflammatory response of the gum, the healing of the wound surface and the normalization of clinical tests, by no means detected,

; 1spolzova Gia present agent allows the effect achieved simultaneously protect the wound poverhnos- t-n and sustained local effect nap- ravlen1gogo dioksidina, present a wide spectrum of action and possessing antimicrobial activity against staphylococcus, streptococcus, pseudomonas ki lechnoy dad, kotorsh most nstrechagot- with pathological gingival carnan of patients with periodontal disease,

Claims (1)

The progress of complex treatment of parodontosis with adhesive protective tooth-gingival band 5 containing dioxidine revealed its advantages compared with the control group, which used a bandage based on zinc oxide and stone oil. The Stem composition had a pronounced anti-inflammatory, hemostatic and antimicrobial oil, hemostatic and antimicrobial oil had anti-inflammatory, hemostatic and antimicrobial oil. action with all steg; en x periodontal disease. The dressing was well tolerated, it differed in its strength and ease of use, it was self-absorbed. There were no signs of irritation of the mucous membrane; a steady stabilization process began. The medicinal substance was delivered to the parodont from a kind of depot, the prolongation of its effect was achieved, the Term of treatment of patients was reduced by 1.5-2 times, the Invention Formula Medication for the treatment of periodontal disease, containing the base and anti-inflammatory substance, characterized in that, in order to reduce 38792 The treatment time, it contains dioxidine, ethyl-X-cyanoacrylate, butyl-0 (-cyanoacrylate, orthoxy acid, microencapsulated in polyvinshirrolone, in the following ratios of components, wt.%: Dioxydin2A-AO Ethyl o (cyanac-0rilat 20-33 Butyl-o (cyanacrylate20-33 Orotovy acid microcapsule-15 in polyvinylpyrrolidone 10-20