SU1174436A1 - Method of producing mixed ethers of orthophosphoric acid - Google Patents
Method of producing mixed ethers of orthophosphoric acid Download PDFInfo
- Publication number
- SU1174436A1 SU1174436A1 SU843712179A SU3712179A SU1174436A1 SU 1174436 A1 SU1174436 A1 SU 1174436A1 SU 843712179 A SU843712179 A SU 843712179A SU 3712179 A SU3712179 A SU 3712179A SU 1174436 A1 SU1174436 A1 SU 1174436A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- mixed ethers
- producing mixed
- orthophosphoric acid
- acid ester
- acid
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract description 5
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 title abstract 3
- 150000002170 ethers Chemical class 0.000 title 1
- 235000011007 phosphoric acid Nutrition 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract description 3
- 125000003118 aryl group Chemical group 0.000 abstract description 2
- 238000006243 chemical reaction Methods 0.000 abstract description 2
- 239000002253 acid Substances 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 229920001567 vinyl ester resin Polymers 0.000 abstract 1
- YRKCREAYFQTBPV-UHFFFAOYSA-N acetylacetone Chemical compound CC(=O)CC(C)=O YRKCREAYFQTBPV-UHFFFAOYSA-N 0.000 description 6
- ZSIAUFGUXNUGDI-UHFFFAOYSA-N hexan-1-ol Chemical compound CCCCCCO ZSIAUFGUXNUGDI-UHFFFAOYSA-N 0.000 description 2
- -1 (2-keto-3-penten-4-yl) phosphite Chemical compound 0.000 description 1
- KPWDGTGXUYRARH-UHFFFAOYSA-N 2,2,2-trichloroethanol Chemical compound OCC(Cl)(Cl)Cl KPWDGTGXUYRARH-UHFFFAOYSA-N 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- BTSGBVKFEJMBGW-UHFFFAOYSA-N diethyl hexyl phosphite Chemical compound CCCCCCOP(OCC)OCC BTSGBVKFEJMBGW-UHFFFAOYSA-N 0.000 description 1
- DHTQKXHLXVUBCF-UHFFFAOYSA-N diethyl phenyl phosphate Chemical compound CCOP(=O)(OCC)OC1=CC=CC=C1 DHTQKXHLXVUBCF-UHFFFAOYSA-N 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 150000002903 organophosphorus compounds Chemical class 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 150000003014 phosphoric acid esters Chemical class 0.000 description 1
- OJMIONKXNSYLSR-UHFFFAOYSA-N phosphorous acid Chemical compound OP(O)O OJMIONKXNSYLSR-UHFFFAOYSA-N 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Abstract
СПОСОБ ПОЛУЧЕНИЯ СМЕШАННЫХ ЭФИРОВ ФОСФОРИСТОЙ КИСЛОТЫ общей . формулы (RO) POR, где В - низший алкил; R - апкил или арил, взаимодействием эфира диалкилфосфористой кислоты со спиртом, отличающийс тем, что, с целью повышени выхода целевых продуктов и упрощени процесса, в качестве эфира диалкилфосфористой кислоты используют виниловый эфир диалкилфосфористой кислоты и взаимодействие провод т при 20-60 С. (ОMETHOD OF OBTAINING MIXED ESHRES OF PHOSPHOROIC ACID. Formulas (RO) POR, where B is lower alkyl; R is apkyl or aryl, by reacting dialkylphosphorous acid ester with alcohol, characterized in that, in order to increase the yield of target products and simplify the process, dialkylphosphorous acid vinyl ester is used as dialkylphosphorous acid ester and the reaction is carried out at 20-60 ° C (O
Description
4 JSb4 JSb
СО ОдCO od
V V
Изобретение относитс к химии фосфорорганических соединений, а именно к усовершенствованному способу получени смешанных эфиров фосфористой кислоты общей формулыThis invention relates to the chemistry of organophosphorus compounds, namely to an improved method for preparing mixed phosphoric acid esters of the general formula
(RO)2POR (Tilj где R - низший алкил;(RO) 2POR (Tilj where R is lower alkyl;
R - алкил или арил, которые вл ютс исходными соединени ми в фосфорорганическом синтезе и могут быть использованы при получении пестицидов и лекарственньЬс веществ.R is alkyl or aryl, which are starting compounds in organophosphorus synthesis and can be used in the preparation of pesticides and drugs.
Целью изобретени вл етс повышение выхода целевых продуктов и упрощение процесса.The aim of the invention is to increase the yield of target products and simplify the process.
Пример . Получение диэтилгексилфосфита .An example. Getting diethylhexylphosphite.
К П г (0,05 моль ) диэтил-(2-кето -З-пентек-4-ил )фосфита прибавл ют при перемешивании 5,1 г (.0,05 моль) гексилового спирта. После прохождени слабой экзотермической реакции (разогревание до )смесь перемешивают при комнатной температуре в течение I ч и перегонкой получают 3,8 г (76% ) ацетилацетона с т.кир. А5С /10 мм рт.ст., cL|o,9936, п 1,4512 и 9,4 г (84,6%) дизтил44362To Pg (0.05 mol) of diethyl- (2-keto-3-pentek-4-yl) phosphite, 5.1 g (.0.05 mol) of hexyl alcohol was added with stirring. After passing through a weak exothermic reaction (heating to), the mixture is stirred at room temperature for 1 h and distillation gives 3.8 g (76%) of acetylacetone with K.p. A5C / 10 mmHg, cL | o, 9936, p 1.4512, and 9.4 g (84.6%) dystil 44362
гёксилфосфита ст.кип, ммрт.ст. dj 0,9376, п| 1,4273, + 140 м.дТxyxylphosphite st.kip, mmr.st. dj 0.9376, p | 1.4273, + 140 mdT
Найдено, % С 54,21; Н 10,49; Р 13,99.Found,% C 54.21; H 10.49; P 13.99.
5С оН ОзРйлчислено , %: С 54,09; Н 10,35; Р 13,94..5С оН It is indicated,%: С 54.09; H 10.35; R 13.94 ..
П р и м е р 2. Получение дизтил- . , /9,/9 -трихлорзтилфосфита.PRI mme R 2. Getting diztil-. , / 9, / 9-trichlorostilphosphite.
В услови х примера 1 получают, иэ 11 г (0,05 моль) дизтил-(2-кето-3-пентен-4-ил )фосфита и 7,5 г (0,05 моль) трихлорзтанола 10,4 г (75,5%) дизтил р В, ft -трихлорзтилфосфита с т. кип. ,07 мм рт.ст., (14 1,273й,Under the conditions of Example 1, 11 g (0.05 mol) of diztil- (2-keto-3-penten-4-yl) phosphite and 7.5 g (0.05 mol) of trichloroethanol 10.4 g (75%) are obtained. , 5%) diztile p In, ft - trichlorostilphosphite with t. Kip. , 07 mm Hg, (14 1.273y,
1,4615, сЛр + 138 м.д. и 4,1 г 2%) ацетилацетона с т.кип. ,1.4615, slr + 138 ppm and 4.1 g of 2%) acetylacetone with a bp. ,
„20"20
d 0,9861, п 1,4508d 0.9861, p 1.4508
П р и м е р 3. Получение дизтилфенилфос4 1та .PRI me R 3. Obtaining dystilfenil 4 1ta.
В услови х примера 1 получают из П г (0,05 моль) (2-кето-3-пентен-4-ил )фосфита и 4,7 г (0,05 моль) фенола 8,5 г (79,4%) диэтилфенилфосфита с т.кип. /10. мм рт.ст., df 1,0651, rf 1,4931, еЛр 135 м.д. и 3,7 г (.74%) ацетилацетона .Under the conditions of Example 1, P g (0.05 mol) (2-keto-3-penten-4-yl) phosphite and 4.7 g (0.05 mol) phenol 8.5 g (79.4% ) diethylphenyl phosphate with so Kip. /ten. mmHg, df 1.0651, rf 1.4931, eLr 135 ppm and 3.7 g (.74%) of acetylacetone.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU843712179A SU1174436A1 (en) | 1984-03-16 | 1984-03-16 | Method of producing mixed ethers of orthophosphoric acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU843712179A SU1174436A1 (en) | 1984-03-16 | 1984-03-16 | Method of producing mixed ethers of orthophosphoric acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU1174436A1 true SU1174436A1 (en) | 1985-08-23 |
Family
ID=21107938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU843712179A SU1174436A1 (en) | 1984-03-16 | 1984-03-16 | Method of producing mixed ethers of orthophosphoric acid |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU1174436A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012046114A1 (en) * | 2010-10-07 | 2012-04-12 | United Phosphorus Limited | Preparing higher trialkyl phosphites |
-
1984
- 1984-03-16 SU SU843712179A patent/SU1174436A1/en active
Non-Patent Citations (1)
| Title |
|---|
| Петров К.А. и др. Переэтерифнкаци фосфитов и фосфинитов одноатомными спиртами и фенолами. - Успехи химии, 1966, 35, вьш. 8, с. 1477. Hoffman F.W. et al. The Transesterification of Trialkyl Phosphites vith Aliphatie Alcohols - J.Am, Chem.Soc., 1956, 78 20, p. 5817. * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012046114A1 (en) * | 2010-10-07 | 2012-04-12 | United Phosphorus Limited | Preparing higher trialkyl phosphites |
| GB2489896A (en) * | 2010-10-07 | 2012-10-10 | United Phosphorus Ltd | Preparing higher trialkyl phosphites |
| GB2489896B (en) * | 2010-10-07 | 2013-02-20 | United Phosphorus Ltd | Preparing higher trialkyl phosphites |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SU710518A3 (en) | Method of preparing tertiary phosphines | |
| SU1174436A1 (en) | Method of producing mixed ethers of orthophosphoric acid | |
| US4160773A (en) | Synthetic alkyl esters of phospholipid acid, structural analogs thereof and a process for their manufacture and their use | |
| SU1203095A1 (en) | Method of producing 2-phosphonsubstituted 1,3-diketones | |
| SU1188176A1 (en) | Method of joint production of aryl- and diaryl-chlorphosphines | |
| SU527437A1 (en) | Method for producing α-ethoxyvinyl alkylphosphinic acid chlorides | |
| US4562011A (en) | Process for preparing aryl phosphates | |
| SU720003A1 (en) | Method of preparing phosphacyclobetaines | |
| SU700519A1 (en) | Method of preparing substituted oxaazaphospholenes | |
| SU555109A1 (en) | Method for preparing 0-alkyl- (cycloalkyl) -2-hydroxy-3-chloropropylphenyl (benzyl) thiophosphonates | |
| SU1404509A1 (en) | Method of producing beta-chloroalkyl esters of phosphocarbolic acids | |
| SU478012A1 (en) | Method for preparing mixed dialkyl phosphites | |
| SU1147713A1 (en) | Method of obtaining dialkyl-(3,5-di-tert-butyl-4-oxyphenyl)phosphates | |
| SU740786A1 (en) | Method of preparing phosphorylated ethylamides of aliphatic dicarboxylic acids | |
| SU524805A1 (en) | Method for preparing o-alkyl-o-aryl-1-hydroxy-2,2,2-trichloroethylphosphonates | |
| US4781867A (en) | Process for making phosphinic or phosphonic acid chlorides | |
| SU502007A1 (en) | The method of obtaining 2-chloroethyloxyphenylphosphite | |
| SU455113A1 (en) | The method of obtaining equimolecular mixtures of mono - and dialkylphosphites | |
| SU374321A1 (en) | Method of producing isocyanide dichloride thiophosphoric acid | |
| SU536191A1 (en) | The method of producing dichloroanhydrides of α-chloro-α-phenylvinylphosphonic acids | |
| SU679587A1 (en) | Method of obtaining monoxydes of asymmetric diphosphines | |
| SU615086A1 (en) | Method of obtaining 0,0-alkylphenylethylphosphonates | |
| SU1397452A1 (en) | Method of producing 2-chloralkyldichlorophosphites | |
| SU1030366A1 (en) | Process for preparing 2-alkoxy-2-iodoalkenyl dialkylphosphines | |
| SU461933A1 (en) | Method for producing bromofluoroanhydride-bromoalkylphosphonic acids |