SMT202200024T1 - Forma di triidrato cristallino di acido(3s,3s')4,4'-disulfanodiilbis (3-amminobutano 1-solfonico) - Google Patents
Forma di triidrato cristallino di acido(3s,3s')4,4'-disulfanodiilbis (3-amminobutano 1-solfonico)Info
- Publication number
- SMT202200024T1 SMT202200024T1 SM20220024T SMT202200024T SMT202200024T1 SM T202200024 T1 SMT202200024 T1 SM T202200024T1 SM 20220024 T SM20220024 T SM 20220024T SM T202200024 T SMT202200024 T SM T202200024T SM T202200024 T1 SMT202200024 T1 SM T202200024T1
- Authority
- SM
- San Marino
- Prior art keywords
- disulfanediylbis
- aminobutane
- sulfonic acid
- trihydrate form
- crystalline trihydrate
- Prior art date
Links
- HJPXZXVKLGEMGP-YUMQZZPRSA-N (3s)-3-amino-4-[[(2s)-2-amino-4-sulfobutyl]disulfanyl]butane-1-sulfonic acid Chemical compound OS(=O)(=O)CC[C@H](N)CSSC[C@@H](N)CCS(O)(=O)=O HJPXZXVKLGEMGP-YUMQZZPRSA-N 0.000 title 1
- 150000004684 trihydrates Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
- C07C303/22—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof from sulfonic acids, by reactions not involving the formation of sulfo or halosulfonyl groups; from sulfonic halides by reactions not involving the formation of halosulfonyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
- C07C319/24—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides by reactions involving the formation of sulfur-to-sulfur bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/12—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms
- C07C321/14—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10306099A EP2439192A1 (en) | 2010-10-07 | 2010-10-07 | Method for the preparation of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) |
| EP18177972.9A EP3395796B1 (en) | 2010-10-07 | 2011-10-07 | A crystalline trihydrate form of (3s,3s') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT202200024T1 true SMT202200024T1 (it) | 2022-05-12 |
Family
ID=43558332
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM20180510T SMT201800510T1 (it) | 2010-10-07 | 2011-10-07 | Metodo per la preparazione di acido(3s,3s')4,4'-disulfanodiilbis (3-amminobutano 1-solfonico). |
| SM20220024T SMT202200024T1 (it) | 2010-10-07 | 2011-10-07 | Forma di triidrato cristallino di acido(3s,3s')4,4'-disulfanodiilbis (3-amminobutano 1-solfonico) |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM20180510T SMT201800510T1 (it) | 2010-10-07 | 2011-10-07 | Metodo per la preparazione di acido(3s,3s')4,4'-disulfanodiilbis (3-amminobutano 1-solfonico). |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US9187418B2 (it) |
| EP (3) | EP2439192A1 (it) |
| JP (1) | JP5921556B2 (it) |
| KR (2) | KR101869366B1 (it) |
| CN (1) | CN103228624B (it) |
| AR (1) | AR083360A1 (it) |
| AU (1) | AU2011311483B2 (it) |
| BR (2) | BR112013008404B1 (it) |
| CA (2) | CA2813834C (it) |
| CY (2) | CY1120859T1 (it) |
| DK (2) | DK2625163T3 (it) |
| EA (1) | EA021612B1 (it) |
| ES (2) | ES2689246T3 (it) |
| HR (2) | HRP20220031T1 (it) |
| HU (2) | HUE058031T2 (it) |
| IL (1) | IL225557A (it) |
| LT (2) | LT3395796T (it) |
| MX (1) | MX2013003863A (it) |
| NZ (1) | NZ608971A (it) |
| PL (2) | PL3395796T3 (it) |
| PT (2) | PT2625163T (it) |
| RS (2) | RS62838B1 (it) |
| SI (2) | SI3395796T1 (it) |
| SM (2) | SMT201800510T1 (it) |
| TW (1) | TWI532710B (it) |
| WO (1) | WO2012045849A1 (it) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2439192A1 (en) | 2010-10-07 | 2012-04-11 | Quantum Genomics | Method for the preparation of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) |
| EP2722327A1 (en) | 2012-10-22 | 2014-04-23 | Quantum Genomics | Crystalline phase of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) with L-lysine |
| US10501426B1 (en) | 2019-01-11 | 2019-12-10 | King Saud University | Synthesis of thiazole derivative as anticancer and anti-antibiotics resistant bacteria agent |
| TW202100146A (zh) | 2019-03-11 | 2021-01-01 | 法商量子基因科技有限公司 | 用於治療高血壓或心衰竭的化合物及包含其之組成物 |
| CN111892557B (zh) * | 2019-05-05 | 2022-11-08 | 河北圣泰材料股份有限公司 | 哌嗪类成膜离子液体的合成方法 |
| WO2022225712A1 (en) * | 2021-04-22 | 2022-10-27 | Teva Pharmaceuticals International Gmbh | Solid state forms of firibastat and processes for preparation thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5596095A (en) * | 1994-12-12 | 1997-01-21 | Procept, Inc. | Formation and utility of sulfonic acid protecting groups |
| ES2309336T3 (es) * | 2002-07-16 | 2008-12-16 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Derivados de 4,4-ditiobis-(3-aminobutano-1-sulfanatos) nuevos y composiciones que los contienen. |
| FR2858617A1 (fr) * | 2003-08-06 | 2005-02-11 | Inst Nat Sante Rech Med | Derives de 4',4'-dithiobis-(3-aminobutane-1-sulfonate-1- sulfonates) nouveaux et compositions les contenant |
| CN101845003A (zh) * | 2010-01-29 | 2010-09-29 | 华东理工大学 | N-三(羟甲基)甲基-3-氨基丙磺酸化合物及其制备方法 |
| EP2439192A1 (en) | 2010-10-07 | 2012-04-11 | Quantum Genomics | Method for the preparation of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) |
-
2010
- 2010-10-07 EP EP10306099A patent/EP2439192A1/en not_active Withdrawn
-
2011
- 2011-10-06 TW TW100136334A patent/TWI532710B/zh active
- 2011-10-07 BR BR112013008404-9A patent/BR112013008404B1/pt not_active IP Right Cessation
- 2011-10-07 SM SM20180510T patent/SMT201800510T1/it unknown
- 2011-10-07 PL PL18177972T patent/PL3395796T3/pl unknown
- 2011-10-07 CA CA2813834A patent/CA2813834C/en active Active
- 2011-10-07 SI SI201132028T patent/SI3395796T1/sl unknown
- 2011-10-07 MX MX2013003863A patent/MX2013003863A/es active IP Right Grant
- 2011-10-07 EP EP11769843.1A patent/EP2625163B1/en active Active
- 2011-10-07 ES ES11769843.1T patent/ES2689246T3/es active Active
- 2011-10-07 EA EA201300440A patent/EA021612B1/ru unknown
- 2011-10-07 HU HUE18177972A patent/HUE058031T2/hu unknown
- 2011-10-07 ES ES18177972T patent/ES2903434T3/es active Active
- 2011-10-07 HR HRP20220031TT patent/HRP20220031T1/hr unknown
- 2011-10-07 PT PT11769843T patent/PT2625163T/pt unknown
- 2011-10-07 LT LTEP18177972.9T patent/LT3395796T/lt unknown
- 2011-10-07 PL PL11769843T patent/PL2625163T3/pl unknown
- 2011-10-07 CA CA3016057A patent/CA3016057C/en active Active
- 2011-10-07 DK DK11769843.1T patent/DK2625163T3/en active
- 2011-10-07 CN CN201180056371.6A patent/CN103228624B/zh not_active Expired - Fee Related
- 2011-10-07 BR BR122021023430-2A patent/BR122021023430B1/pt active IP Right Grant
- 2011-10-07 US US13/878,003 patent/US9187418B2/en active Active
- 2011-10-07 SI SI201131578T patent/SI2625163T1/sl unknown
- 2011-10-07 SM SM20220024T patent/SMT202200024T1/it unknown
- 2011-10-07 KR KR1020137011888A patent/KR101869366B1/ko active Active
- 2011-10-07 HU HUE11769843A patent/HUE040484T2/hu unknown
- 2011-10-07 NZ NZ608971A patent/NZ608971A/en unknown
- 2011-10-07 EP EP18177972.9A patent/EP3395796B1/en active Active
- 2011-10-07 DK DK18177972.9T patent/DK3395796T3/da active
- 2011-10-07 WO PCT/EP2011/067524 patent/WO2012045849A1/en active Application Filing
- 2011-10-07 AU AU2011311483A patent/AU2011311483B2/en active Active
- 2011-10-07 JP JP2013532214A patent/JP5921556B2/ja not_active Expired - Fee Related
- 2011-10-07 LT LTEP11769843.1T patent/LT2625163T/lt unknown
- 2011-10-07 KR KR1020187008022A patent/KR101893894B1/ko active Active
- 2011-10-07 PT PT181779729T patent/PT3395796T/pt unknown
- 2011-10-07 RS RS20211589A patent/RS62838B1/sr unknown
- 2011-10-07 RS RS20181090A patent/RS57670B1/sr unknown
- 2011-10-11 AR ARP110103726A patent/AR083360A1/es active IP Right Grant
-
2013
- 2013-04-04 IL IL225557A patent/IL225557A/en active IP Right Grant
-
2015
- 2015-10-27 US US14/923,615 patent/US9340497B2/en not_active Expired - Fee Related
-
2018
- 2018-09-07 HR HRP20181437TT patent/HRP20181437T1/hr unknown
- 2018-09-19 CY CY181100970T patent/CY1120859T1/el unknown
-
2022
- 2022-01-13 CY CY20221100031T patent/CY1124919T1/el unknown
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