SK283332B6 - Difenylalkyltetrahydropyridíny, spôsob ich prípravy a farmaceutické kompozície, ktoré ich obsahujú - Google Patents

Difenylalkyltetrahydropyridíny, spôsob ich prípravy a farmaceutické kompozície, ktoré ich obsahujú Download PDF

Info

Publication number: SK283332B6
Authority: SK; Slovakia
Prior art keywords: tetrahydropyridine; formula; group; ethyl; trifluoromethylphenyl
Prior art date: 1996-12-13

Application number

SK787-99A

Other languages

English (en)

Slovak (sk)

Other versions

SK78799A3 (en

Inventor

Marco Baroni

Rosanna Cardamone

Jacqueline Fournier

Umberto Guzzi

Original Assignee

Sanofi-Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-13

Filing date

1997-12-12

Publication date

2003-06-03

1997-12-12 Application filed by Sanofi-Synthelabo filed Critical Sanofi-Synthelabo

1999-12-10 Publication of SK78799A3 publication Critical patent/SK78799A3/sk

2003-06-03 Publication of SK283332B6 publication Critical patent/SK283332B6/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)

SK787-99A 1996-12-13 1997-12-12 Difenylalkyltetrahydropyridíny, spôsob ich prípravy a farmaceutické kompozície, ktoré ich obsahujú SK283332B6 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9615336A FR2757161B1 (fr)	1996-12-13	1996-12-13	Diphenylalkyl-tetrahydropyridines
PCT/FR1997/002289 WO1998025904A1 (fr)	1996-12-13	1997-12-12	Diphenylalkyl-tetrahydropyridines, procede pour leur preparation et composition pharmaceutique les contenant

Publications (2)

Publication Number	Publication Date
SK78799A3 SK78799A3 (en)	1999-12-10
SK283332B6 true SK283332B6 (sk)	2003-06-03

Family

ID=9498642

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK787-99A SK283332B6 (sk)	1996-12-13	1997-12-12	Difenylalkyltetrahydropyridíny, spôsob ich prípravy a farmaceutické kompozície, ktoré ich obsahujú

Country Status (31)

Country	Link
US (1)	US6124318A (sr)
EP (1)	EP0950049B1 (sr)
JP (1)	JP2001505903A (sr)
KR (1)	KR100549656B1 (sr)
CN (1)	CN1144784C (sr)
AT (1)	ATE207056T1 (sr)
AU (1)	AU730142B2 (sr)
BR (1)	BR9713926A (sr)
CA (1)	CA2274946C (sr)
CY (1)	CY2282B1 (sr)
CZ (1)	CZ290242B6 (sr)
DE (1)	DE69707504T2 (sr)
DK (1)	DK0950049T3 (sr)
EE (1)	EE03764B1 (sr)
ES (1)	ES2167805T3 (sr)
FR (1)	FR2757161B1 (sr)
HK (1)	HK1024001A1 (sr)
HU (1)	HUP0001437A3 (sr)
IL (2)	IL130001A0 (sr)
IS (1)	IS2001B (sr)
NO (1)	NO313282B1 (sr)
NZ (1)	NZ336032A (sr)
PL (1)	PL192926B1 (sr)
PT (1)	PT950049E (sr)
RS (1)	RS49672B (sr)
RU (1)	RU2198874C2 (sr)
SI (1)	SI0950049T1 (sr)
SK (1)	SK283332B6 (sr)
TR (1)	TR199901290T2 (sr)
UA (1)	UA52708C2 (sr)
WO (1)	WO1998025904A1 (sr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2763847B1 (fr) *	1997-05-28	2003-06-06	Sanofi Sa	Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
EP1328261A2 (en) *	2000-04-12	2003-07-23	Minerva Biotechnologies Corporation	Treatment of neurodegenerative disease
AU2002314744A1 (en)	2001-04-17	2002-10-28	Sepracor, Inc.	Thiazole and other heterocyclic ligands and use thereof
CA2551946A1 (en) *	2003-12-31	2005-07-21	Actavis Group Hf	Immediate, controlled and sustained release formulations of galantamine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1321701A (en) *	1969-10-01	1973-06-27	Continental Pharma	Amino-alcohols their salts and process for prepairing the same
BE775611A (fr) *	1970-11-24	1972-03-16	Synthelabo	Derives de la (diphenyl-3,3 propyl-1)-1 piperidine, leur preparation etles medicaments qui en contiennent
US5266573A (en) *	1989-08-07	1993-11-30	Elf Sanofi	Trifluoromethylphenyltetrahydropyridines for the treatment and/or prophylaxis of intestinal motility disorders
FR2650505B1 (fr) *	1989-08-07	1994-06-03	Midy Spa	Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale
FR2662355B1 (fr) *	1990-05-22	1994-11-10	Sanofi Sa	Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
US5512584A (en) *	1991-04-16	1996-04-30	Basf Aktiengesellschaft	1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof
HU211019B (en) *	1991-12-02	1995-09-28	Richter Gedeon Vegyeszet	Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds
DK148392D0 (da) *	1992-12-09	1992-12-09	Lundbeck & Co As H	Heterocykliske forbindelser

1996
- 1996-12-13 FR FR9615336A patent/FR2757161B1/fr not_active Expired - Fee Related
1997
- 1997-12-11 US US09/331,005 patent/US6124318A/en not_active Expired - Fee Related
- 1997-12-12 BR BR9713926A patent/BR9713926A/pt not_active Application Discontinuation
- 1997-12-12 WO PCT/FR1997/002289 patent/WO1998025904A1/fr not_active Application Discontinuation
- 1997-12-12 PL PL334073A patent/PL192926B1/pl not_active IP Right Cessation
- 1997-12-12 ES ES97951326T patent/ES2167805T3/es not_active Expired - Lifetime
- 1997-12-12 TR TR1999/01290T patent/TR199901290T2/xx unknown
- 1997-12-12 HU HU0001437A patent/HUP0001437A3/hu unknown
- 1997-12-12 CA CA002274946A patent/CA2274946C/en not_active Expired - Fee Related
- 1997-12-12 AU AU54895/98A patent/AU730142B2/en not_active Ceased
- 1997-12-12 AT AT97951326T patent/ATE207056T1/de not_active IP Right Cessation
- 1997-12-12 SI SI9730241T patent/SI0950049T1/xx unknown
- 1997-12-12 SK SK787-99A patent/SK283332B6/sk unknown
- 1997-12-12 RS YUP-263/99A patent/RS49672B/sr unknown
- 1997-12-12 DK DK97951326T patent/DK0950049T3/da active
- 1997-12-12 DE DE69707504T patent/DE69707504T2/de not_active Expired - Fee Related
- 1997-12-12 CZ CZ19992110A patent/CZ290242B6/cs not_active IP Right Cessation
- 1997-12-12 IL IL13000197A patent/IL130001A0/xx active IP Right Grant
- 1997-12-12 RU RU99115082/04A patent/RU2198874C2/ru not_active IP Right Cessation
- 1997-12-12 PT PT97951326T patent/PT950049E/pt unknown
- 1997-12-12 JP JP52632398A patent/JP2001505903A/ja not_active Ceased
- 1997-12-12 EE EEP199900238A patent/EE03764B1/xx not_active IP Right Cessation
- 1997-12-12 UA UA99063287A patent/UA52708C2/uk unknown
- 1997-12-12 NZ NZ336032A patent/NZ336032A/xx unknown
- 1997-12-12 CN CNB971805830A patent/CN1144784C/zh not_active Expired - Fee Related
- 1997-12-12 KR KR1019997005202A patent/KR100549656B1/ko not_active IP Right Cessation
- 1997-12-12 EP EP97951326A patent/EP0950049B1/fr not_active Expired - Lifetime
1999
- 1999-05-18 IL IL130001A patent/IL130001A/en not_active IP Right Cessation
- 1999-06-10 IS IS5074A patent/IS2001B/is unknown
- 1999-06-11 NO NO19992870A patent/NO313282B1/no unknown
2000
- 2000-05-31 HK HK00103246A patent/HK1024001A1/xx not_active IP Right Cessation
2002
- 2002-05-15 CY CY0200036A patent/CY2282B1/xx unknown

Also Published As

Publication number	Publication date
NO992870D0 (no)	1999-06-11
NO313282B1 (no)	2002-09-09
CZ290242B6 (cs)	2002-06-12
KR100549656B1 (ko)	2006-02-08
EE03764B1 (et)	2002-06-17
HK1024001A1 (en)	2000-09-29
YU26399A (sh)	2000-03-21
KR20000069421A (ko)	2000-11-25
BR9713926A (pt)	2000-03-21
JP2001505903A (ja)	2001-05-08
IS5074A (is)	1999-06-10
EP0950049B1 (fr)	2001-10-17
DK0950049T3 (da)	2002-01-28
ES2167805T3 (es)	2002-05-16
RU2198874C2 (ru)	2003-02-20
SK78799A3 (en)	1999-12-10
DE69707504D1 (de)	2001-11-22
FR2757161A1 (fr)	1998-06-19
US6124318A (en)	2000-09-26
CN1240428A (zh)	2000-01-05
DE69707504T2 (de)	2002-06-27
RS49672B (sr)	2007-11-15
HUP0001437A2 (hu)	2000-09-28
NO992870L (no)	1999-08-11
TR199901290T2 (xx)	1999-08-23
AU5489598A (en)	1998-07-03
IL130001A0 (en)	2000-02-29
FR2757161B1 (fr)	1999-03-12
PL192926B1 (pl)	2006-12-29
AU730142B2 (en)	2001-03-01
ATE207056T1 (de)	2001-11-15
UA52708C2 (uk)	2003-01-15
PL334073A1 (en)	2000-01-31
EE9900238A (et)	1999-12-15
HUP0001437A3 (en)	2001-12-28
SI0950049T1 (en)	2002-10-31
CA2274946A1 (en)	1998-06-18
CZ211099A3 (cs)	1999-09-15
EP0950049A1 (fr)	1999-10-20
CA2274946C (en)	2005-09-20
WO1998025904A1 (fr)	1998-06-18
IS2001B (is)	2005-04-15
CY2282B1 (en)	2003-07-04
NZ336032A (en)	2000-12-22
IL130001A (en)	2006-04-10
PT950049E (pt)	2002-03-28
CN1144784C (zh)	2004-04-07

Publication	Publication Date	Title
JP3147906B2 (ja)	2001-03-19	神経栄養活性および神経保護活性を有する４−アリール−１−フェニルアルキル−１，２，３，６−テトラヒドロピリジン
US4999355A (en)	1991-03-12	Isoindolinone derivatives, processes for preparing them and medicines containing them
SK283332B6 (sk)	2003-06-03	Difenylalkyltetrahydropyridíny, spôsob ich prípravy a farmaceutické kompozície, ktoré ich obsahujú
US7297799B2 (en)	2007-11-20	Preparation of benzoylalkyl-1,2,3,6-tetrahydropyridines and use thereof
SK78699A3 (en)	2000-01-18	1-phenylalkyl-1,2,3,6-tetrahydropyridines for treating alzheimer's disease
MXPA99005651A (es)	2000-05-01	Uso de benzoilalquil-1,2,3,6-tetrahidropiridinas
MXPA99005108A (en)	2000-06-01	1-phenylalkyl-1,2,3,6-tetrahydropyridines for treating alzheimer's disease