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SK281970B6 - Peptidy s modifikáciami na n-konci, spôsob ich prípravy, ich použitie a farmaceutické kompozície s ich obsahom - Google Patents

Peptidy s modifikáciami na n-konci, spôsob ich prípravy, ich použitie a farmaceutické kompozície s ich obsahom Download PDF

Info

Publication number
SK281970B6
SK281970B6 SK289-93A SK28993A SK281970B6 SK 281970 B6 SK281970 B6 SK 281970B6 SK 28993 A SK28993 A SK 28993A SK 281970 B6 SK281970 B6 SK 281970B6
Authority
SK
Slovakia
Prior art keywords
arg
formula
peptide
fmoc
gly
Prior art date
Application number
SK289-93A
Other languages
English (en)
Slovak (sk)
Other versions
SK28993A3 (en
Inventor
Gerhard Breipohl
Stephan Henke
Jochen Knolle
Bernward Sch�Lkens
Hans-Georg Alpermann
Hermann Gerhards
Klaus Wirth
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of SK28993A3 publication Critical patent/SK28993A3/sk
Publication of SK281970B6 publication Critical patent/SK281970B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/18Kallidins; Bradykinins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Transceivers (AREA)
  • Mobile Radio Communication Systems (AREA)
SK289-93A 1992-04-04 1993-04-02 Peptidy s modifikáciami na n-konci, spôsob ich prípravy, ich použitie a farmaceutické kompozície s ich obsahom SK281970B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4211406 1992-04-04

Publications (2)

Publication Number Publication Date
SK28993A3 SK28993A3 (en) 1993-11-10
SK281970B6 true SK281970B6 (sk) 2001-09-11

Family

ID=6456125

Family Applications (1)

Application Number Title Priority Date Filing Date
SK289-93A SK281970B6 (sk) 1992-04-04 1993-04-02 Peptidy s modifikáciami na n-konci, spôsob ich prípravy, ich použitie a farmaceutické kompozície s ich obsahom

Country Status (25)

Country Link
US (1) US5597803A (fi)
EP (1) EP0564972B1 (fi)
JP (1) JP3426639B2 (fi)
KR (1) KR100273825B1 (fi)
CN (1) CN1040330C (fi)
AT (1) ATE183197T1 (fi)
AU (1) AU667707B2 (fi)
BR (1) BR9301436A (fi)
CA (1) CA2093305A1 (fi)
CZ (1) CZ285698B6 (fi)
DE (1) DE59309726D1 (fi)
DK (1) DK0564972T3 (fi)
ES (1) ES2136626T3 (fi)
FI (1) FI931474A (fi)
GR (1) GR3031543T3 (fi)
HU (1) HU217613B (fi)
IL (1) IL105287A (fi)
MX (1) MX9301926A (fi)
NO (1) NO311941B1 (fi)
NZ (1) NZ247317A (fi)
PL (1) PL175901B1 (fi)
RU (1) RU2109747C1 (fi)
SK (1) SK281970B6 (fi)
TW (1) TW258739B (fi)
ZA (1) ZA932399B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69533704D1 (de) * 1994-03-09 2004-12-02 Cortech Inc Bradykinin-antagonist peptide mit n-substituierten glycinen
FR2739553B1 (fr) 1995-10-06 1998-01-02 Oreal Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
DE19612067A1 (de) * 1996-03-27 1997-10-02 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen
FR2790260B1 (fr) 1999-02-26 2001-05-04 Fournier Ind & Sante Nouveaux composes de n-(benzenesulfonamide), procede de preparation et utilisation en therapeutique
US7105172B1 (en) 1999-11-18 2006-09-12 Bolla John D Treatment of rosacea
US6699486B1 (en) 1999-11-18 2004-03-02 Bolla Corporation Treatment or prevention of photoaging and skin cancer
US20040248809A1 (en) * 2003-02-07 2004-12-09 Aventis Pharma Deutschland Gmbh Use of antagonists of the bradykinin B2 receptor for the treatment of osteoarthrosis
EP3781586B1 (en) 2018-04-20 2024-04-17 Fresenius Kabi iPSUM S.r.l. A method for production of high purity icatibant

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210584A (en) * 1979-01-15 1980-07-01 Eli Lilly And Company Vindesine synthesis
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
US4693993A (en) * 1985-06-13 1987-09-15 Stewart John M Bradykinin antagonist peptides
US4923963A (en) * 1987-09-02 1990-05-08 Nova Technology Limited Partnership Bradykinin antagonist peptides
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
DE3926822A1 (de) * 1989-08-14 1991-02-21 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
DE4013270A1 (de) * 1990-04-26 1991-10-31 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
EP0502987B1 (en) * 1989-12-08 1994-08-31 Trustees Of Boston University Acylated bradykinin antagonists and uses therefor
MX9100717A (es) * 1990-08-24 1992-04-01 Syntex Inc Antagonistas de la bradiquinina

Also Published As

Publication number Publication date
RU2109747C1 (ru) 1998-04-27
ZA932399B (en) 1993-10-19
IL105287A (en) 1999-12-31
PL175901B1 (pl) 1999-03-31
JPH0665289A (ja) 1994-03-08
FI931474A (fi) 1993-10-05
TW258739B (fi) 1995-10-01
CN1077202A (zh) 1993-10-13
CA2093305A1 (en) 1993-10-05
MX9301926A (es) 1993-10-01
NO311941B1 (no) 2002-02-18
DE59309726D1 (de) 1999-09-16
PL298362A1 (en) 1993-10-18
GR3031543T3 (en) 2000-01-31
EP0564972A2 (de) 1993-10-13
SK28993A3 (en) 1993-11-10
AU667707B2 (en) 1996-04-04
FI931474A0 (fi) 1993-04-01
ES2136626T3 (es) 1999-12-01
ATE183197T1 (de) 1999-08-15
JP3426639B2 (ja) 2003-07-14
IL105287A0 (en) 1993-08-18
AU3565193A (en) 1993-10-07
NZ247317A (en) 1995-03-28
BR9301436A (pt) 1993-10-13
CN1040330C (zh) 1998-10-21
CZ285698B6 (cs) 1999-10-13
HUT64775A (en) 1994-02-28
EP0564972B1 (de) 1999-08-11
KR100273825B1 (ko) 2000-12-15
NO931287L (no) 1993-10-05
KR930021656A (ko) 1993-11-22
NO931287D0 (no) 1993-04-02
HU9300972D0 (en) 1993-06-28
US5597803A (en) 1997-01-28
HU217613B (hu) 2000-03-28
CZ57293A3 (en) 1994-03-16
EP0564972A3 (en) 1994-10-05
DK0564972T3 (da) 2000-01-24

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