SI2991983T1 - DERIVATI 2-FENIL ALI 2-HETARIL IMIDAZOL(1,2-a)PIRIDINA - Google Patents
DERIVATI 2-FENIL ALI 2-HETARIL IMIDAZOL(1,2-a)PIRIDINAInfo
- Publication number
- SI2991983T1 SI2991983T1 SI201430205A SI201430205A SI2991983T1 SI 2991983 T1 SI2991983 T1 SI 2991983T1 SI 201430205 A SI201430205 A SI 201430205A SI 201430205 A SI201430205 A SI 201430205A SI 2991983 T1 SI2991983 T1 SI 2991983T1
- Authority
- SI
- Slovenia
- Prior art keywords
- hetaryl
- imidazol
- phenyl
- pyridine derivatives
- pyridine
- Prior art date
Links
- VNHBYKHXBCYPBJ-UHFFFAOYSA-N 5-ethynylimidazo[1,2-a]pyridine Chemical class C#CC1=CC=CC2=NC=CN12 VNHBYKHXBCYPBJ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13165676 | 2013-04-29 | ||
| EP14719326.2A EP2991983B1 (en) | 2013-04-29 | 2014-04-25 | 2-phenyl or 2-hetaryl imidazol[1,2-a]pyridine derivatives |
| PCT/EP2014/058415 WO2014177458A1 (en) | 2013-04-29 | 2014-04-25 | 2-PHENYL OR 2-HETARYL IMIDAZOL[1,2-a]PYRIDINE DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2991983T1 true SI2991983T1 (sl) | 2017-06-30 |
Family
ID=48190297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201430205A SI2991983T1 (sl) | 2013-04-29 | 2014-04-25 | DERIVATI 2-FENIL ALI 2-HETARIL IMIDAZOL(1,2-a)PIRIDINA |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US10138234B2 (sl) |
| EP (1) | EP2991983B1 (sl) |
| JP (1) | JP6212628B2 (sl) |
| KR (2) | KR20160003173A (sl) |
| CN (1) | CN105164125B (sl) |
| AR (1) | AR096119A1 (sl) |
| AU (1) | AU2014261628A1 (sl) |
| BR (1) | BR112015027015A2 (sl) |
| CA (1) | CA2910368A1 (sl) |
| DK (1) | DK2991983T3 (sl) |
| ES (1) | ES2624453T3 (sl) |
| MX (1) | MX2015014353A (sl) |
| PL (1) | PL2991983T3 (sl) |
| RU (1) | RU2015147450A (sl) |
| SG (1) | SG11201508912YA (sl) |
| SI (1) | SI2991983T1 (sl) |
| WO (1) | WO2014177458A1 (sl) |
| ZA (1) | ZA201507389B (sl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201508912YA (en) * | 2013-04-29 | 2015-11-27 | Hoffmann La Roche | 2-PHENYL OR 2-HETARYL IMIDAZOL[1,2-a]PYRIDINE DERIVATIVES |
| BR112015025140A2 (pt) * | 2013-05-23 | 2017-07-18 | Hoffmann La Roche | 2-fenilimidazo[1,2-a]pirimidinas como agentes de imagem |
| CA2920068A1 (en) | 2013-09-26 | 2015-04-02 | F. Hoffmann-La Roche Ag | Imidazo[1,2-a]pyridin-7-amines as imaging tools |
| DK3355699T3 (da) * | 2015-09-29 | 2021-06-07 | Onco Therapy Science Inc | Bicyklisk forbindelse og anvendelse deraf til inhibering af suv39h2 |
| US10865207B2 (en) | 2016-07-22 | 2020-12-15 | Ac Immune S.A. | Compounds for imaging Tau protein aggregates |
| MX386900B (es) | 2016-07-22 | 2025-03-19 | Ac Immune S A Star | Compuestos para formacion de imagenes de agregados de proteinas tau. |
| WO2018165112A1 (en) * | 2017-03-09 | 2018-09-13 | Oncotherapy Science, Inc. | Bicyclic compound and use thereof for inhibiting histone methyltransferase |
| EP3743426A1 (en) | 2018-01-24 | 2020-12-02 | AC Immune SA | Azacarboline compounds for the detection of tau aggregates |
| US11306089B2 (en) | 2018-01-24 | 2022-04-19 | Life Molecular Imaging Limited | Gamma-carboline compounds for the detection of Tau aggregates |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5654436A (en) * | 1995-06-07 | 1997-08-05 | American Home Products Corporation | 2-substituted benzimidazole derivatives |
| CA2444214A1 (en) | 2001-04-23 | 2002-10-31 | The Trustees Of The University Of Pennsylvania | Amyloid plaque aggregation inhibitors and diagnostic imaging agents |
| EP1432453B1 (en) | 2001-08-27 | 2013-08-14 | The Trustees of The University of Pennsylvania | Stilbene derivatives and their use for binding and imaging amyloid plaques |
| EP1956013B1 (en) * | 2005-11-30 | 2016-04-13 | Fujifilm RI Pharma Co., Ltd. | Diagnostic and remedy for disease caused by amyloid aggregation and/or deposition |
| AU2007207053B2 (en) * | 2006-01-17 | 2012-05-24 | F. Hoffmann-La Roche Ag | Aryl-isoxazol-4-yl-imidazo[1,2-a]pyridine useful for the treatment of Alzheimer's disease via GABA receptors |
| EP2023919A4 (en) * | 2006-05-08 | 2010-12-22 | Molecular Neuroimaging Llc | COMPOUNDS AND AMYLOID PROBES FOR THERAPY AND IMAGING USES |
| KR20090025282A (ko) * | 2006-06-21 | 2009-03-10 | 니혼 메디피직스 가부시키가이샤 | 신규 아밀로이드 친화성 화합물 |
| AU2007320581A1 (en) * | 2006-11-17 | 2008-05-22 | Nihon Medi-Physics Co., Ltd. | Novel compounds with affinity for amyloid |
| RU2009124537A (ru) | 2007-01-22 | 2011-02-27 | Астразенека Аб (Se) | НОВЫЕ ГЕТЕРОАРИЛЗАМЕЩЕННЫЕ ПРОИЗВОДНЫЕ ИМИДАЗО(1,2-a)ПИРИДИНОВ |
| US20150377123A1 (en) | 2007-08-01 | 2015-12-31 | United Technologies Corporation | Turbine section of high bypass turbofan |
| EP2216052A4 (en) * | 2007-10-30 | 2012-11-21 | Nihon Mediphysics Co Ltd | USE OF A NEW COMPOUND WITH AFFINITY FOR AMYLOID AND METHOD FOR THE PRODUCTION THEREOF |
| PT2338059E (pt) | 2008-09-23 | 2015-08-03 | Wista Lab Ltd | Ligandos para moléculas de tau agregada |
| ES2530884T3 (es) * | 2009-09-24 | 2015-03-06 | Hoffmann La Roche | Derivados de imidazopiridina o imidazopirimidina como inhibidores de fosfodiesterasa 10A |
| US8703768B2 (en) * | 2010-06-09 | 2014-04-22 | Hoffmann-La Roche Inc. | Nitrogen containing heteroaryl compounds |
| SG11201508912YA (en) | 2013-04-29 | 2015-11-27 | Hoffmann La Roche | 2-PHENYL OR 2-HETARYL IMIDAZOL[1,2-a]PYRIDINE DERIVATIVES |
| CA2920068A1 (en) * | 2013-09-26 | 2015-04-02 | F. Hoffmann-La Roche Ag | Imidazo[1,2-a]pyridin-7-amines as imaging tools |
-
2014
- 2014-04-25 SG SG11201508912YA patent/SG11201508912YA/en unknown
- 2014-04-25 KR KR1020157033882A patent/KR20160003173A/ko not_active Abandoned
- 2014-04-25 KR KR1020177021836A patent/KR20170094001A/ko not_active Withdrawn
- 2014-04-25 DK DK14719326.2T patent/DK2991983T3/en active
- 2014-04-25 WO PCT/EP2014/058415 patent/WO2014177458A1/en not_active Ceased
- 2014-04-25 BR BR112015027015A patent/BR112015027015A2/pt not_active IP Right Cessation
- 2014-04-25 ES ES14719326.2T patent/ES2624453T3/es active Active
- 2014-04-25 MX MX2015014353A patent/MX2015014353A/es unknown
- 2014-04-25 JP JP2016511013A patent/JP6212628B2/ja active Active
- 2014-04-25 CN CN201480024056.9A patent/CN105164125B/zh active Active
- 2014-04-25 AU AU2014261628A patent/AU2014261628A1/en not_active Abandoned
- 2014-04-25 EP EP14719326.2A patent/EP2991983B1/en active Active
- 2014-04-25 PL PL14719326T patent/PL2991983T3/pl unknown
- 2014-04-25 SI SI201430205A patent/SI2991983T1/sl unknown
- 2014-04-25 RU RU2015147450A patent/RU2015147450A/ru not_active Application Discontinuation
- 2014-04-25 CA CA2910368A patent/CA2910368A1/en not_active Abandoned
- 2014-04-28 AR ARP140101744A patent/AR096119A1/es unknown
-
2015
- 2015-10-06 ZA ZA2015/07389A patent/ZA201507389B/en unknown
- 2015-10-28 US US14/925,574 patent/US10138234B2/en active Active
-
2018
- 2018-10-16 US US16/161,299 patent/US11358962B2/en active Active
- 2018-10-16 US US16/161,306 patent/US10975073B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| MX2015014353A (es) | 2016-04-07 |
| KR20160003173A (ko) | 2016-01-08 |
| AR096119A1 (es) | 2015-12-09 |
| CA2910368A1 (en) | 2014-11-06 |
| ZA201507389B (en) | 2017-01-25 |
| CN105164125A (zh) | 2015-12-16 |
| EP2991983A1 (en) | 2016-03-09 |
| DK2991983T3 (en) | 2017-05-08 |
| WO2014177458A1 (en) | 2014-11-06 |
| PL2991983T3 (pl) | 2017-07-31 |
| EP2991983B1 (en) | 2017-03-01 |
| AU2014261628A1 (en) | 2015-10-22 |
| US11358962B2 (en) | 2022-06-14 |
| US20160244441A1 (en) | 2016-08-25 |
| JP2016520046A (ja) | 2016-07-11 |
| US10138234B2 (en) | 2018-11-27 |
| SG11201508912YA (en) | 2015-11-27 |
| JP6212628B2 (ja) | 2017-10-11 |
| ES2624453T3 (es) | 2017-07-14 |
| RU2015147450A (ru) | 2017-06-05 |
| US20190048002A1 (en) | 2019-02-14 |
| KR20170094001A (ko) | 2017-08-16 |
| CN105164125B (zh) | 2017-10-13 |
| US20190048003A1 (en) | 2019-02-14 |
| HK1213555A1 (zh) | 2016-07-08 |
| BR112015027015A2 (pt) | 2017-07-25 |
| US10975073B2 (en) | 2021-04-13 |
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