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SI2624833T1 - Derivati 4-(metilaminofenoksi)piridin-3-il-benzamida za zdravljenje raka - Google Patents

Derivati 4-(metilaminofenoksi)piridin-3-il-benzamida za zdravljenje raka

Info

Publication number
SI2624833T1
SI2624833T1 SI201130409T SI201130409T SI2624833T1 SI 2624833 T1 SI2624833 T1 SI 2624833T1 SI 201130409 T SI201130409 T SI 201130409T SI 201130409 T SI201130409 T SI 201130409T SI 2624833 T1 SI2624833 T1 SI 2624833T1
Authority
SI
Slovenia
Prior art keywords
methylaminophenoxy
pyrdin
treating cancer
benzamide derivatives
benzamide
Prior art date
Application number
SI201130409T
Other languages
English (en)
Inventor
Takashi Nakagawa
Makoto Sakamoto
Kazuya Yamaguchi
Yuki Terauchi
Masamichi Shirakura
Yasuo Harada
Yutaka Kojima
Takumi Sumida
Original Assignee
Otsuka Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co., Ltd. filed Critical Otsuka Pharmaceutical Co., Ltd.
Publication of SI2624833T1 publication Critical patent/SI2624833T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/76Nitrogen atoms to which a second hetero atom is attached

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI201130409T 2010-10-04 2011-10-03 Derivati 4-(metilaminofenoksi)piridin-3-il-benzamida za zdravljenje raka SI2624833T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38939310P 2010-10-04 2010-10-04
EP20110773326 EP2624833B1 (en) 2010-10-04 2011-10-03 4-(methylaminophenoxy)pyrdin-3-yl-benzamide derivatives for treating cancer
PCT/JP2011/073165 WO2012046825A1 (en) 2010-10-04 2011-10-03 4- (methylaminophenoxy) pyrdin- 3 - yl - benzamide derivatives for treating cancer

Publications (1)

Publication Number Publication Date
SI2624833T1 true SI2624833T1 (sl) 2015-03-31

Family

ID=44872549

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201130409T SI2624833T1 (sl) 2010-10-04 2011-10-03 Derivati 4-(metilaminofenoksi)piridin-3-il-benzamida za zdravljenje raka

Country Status (29)

Country Link
US (8) US8946437B2 (sl)
EP (1) EP2624833B1 (sl)
JP (1) JP5715690B2 (sl)
KR (1) KR101797797B1 (sl)
CN (1) CN103189061B (sl)
AR (1) AR083287A1 (sl)
AU (1) AU2011313236B2 (sl)
BR (1) BR112013007841B1 (sl)
CA (1) CA2813153C (sl)
CO (1) CO6660459A2 (sl)
DK (1) DK2624833T3 (sl)
EA (1) EA021627B1 (sl)
ES (1) ES2526574T3 (sl)
HR (1) HRP20141237T1 (sl)
IL (1) IL225520A (sl)
MX (1) MX2013003589A (sl)
MY (1) MY157563A (sl)
NZ (1) NZ609151A (sl)
PH (1) PH12013500605B1 (sl)
PL (1) PL2624833T3 (sl)
PT (1) PT2624833E (sl)
RS (1) RS53749B1 (sl)
SG (1) SG189146A1 (sl)
SI (1) SI2624833T1 (sl)
SM (1) SMT201500056B (sl)
TW (1) TWI526431B (sl)
UA (1) UA110037C2 (sl)
WO (1) WO2012046825A1 (sl)
ZA (1) ZA201302332B (sl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA110037C2 (uk) * 2010-10-04 2015-11-10 Оцука Фармас'Ютікел Ко., Лтд. Похідні 4-(метиламінофенокси)піридин-3-ілбензаміду для лікування раку
JP6066806B2 (ja) * 2012-04-03 2017-01-25 大塚製薬株式会社 医薬
KR20210142700A (ko) 2019-03-25 2021-11-25 오츠카 세이야쿠 가부시키가이샤 항종양 조성물
CN118005541B (zh) * 2023-12-13 2025-05-30 张家港格瑞特化学有限公司 一种双牛磺酸盐及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6022884A (en) * 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use
JP2001089412A (ja) 1999-09-22 2001-04-03 Otsuka Pharmaceut Co Ltd ベンゼン誘導体またはその医薬的に許容される塩
ZA200700811B (en) 2004-08-06 2008-10-29 Otsuka Pharma Co Ltd Aromatic compound
EP1957073B1 (en) 2005-12-05 2014-04-23 Otsuka Pharmaceutical Co., Ltd. Medicinal drug
UA95978C2 (ru) * 2006-10-02 2011-09-26 Оцука Фармас'Ютікел Ко., Лтд. Ингибитор активации stat3/5
UA110037C2 (uk) * 2010-10-04 2015-11-10 Оцука Фармас'Ютікел Ко., Лтд. Похідні 4-(метиламінофенокси)піридин-3-ілбензаміду для лікування раку
KR20210142700A (ko) * 2019-03-25 2021-11-25 오츠카 세이야쿠 가부시키가이샤 항종양 조성물

Also Published As

Publication number Publication date
CN103189061A (zh) 2013-07-03
US20200031773A1 (en) 2020-01-30
US20130267565A1 (en) 2013-10-10
US20210017134A1 (en) 2021-01-21
IL225520A (en) 2016-05-31
EA021627B1 (ru) 2015-07-30
PH12013500605A1 (en) 2013-05-06
US20240417376A1 (en) 2024-12-19
KR20130121826A (ko) 2013-11-06
US20170298023A1 (en) 2017-10-19
ES2526574T3 (es) 2015-01-13
US8946437B2 (en) 2015-02-03
EP2624833A1 (en) 2013-08-14
IL225520A0 (en) 2013-06-27
US20180265471A1 (en) 2018-09-20
AU2011313236A1 (en) 2013-04-18
BR112013007841A2 (pt) 2016-06-07
MX2013003589A (es) 2013-06-24
CA2813153C (en) 2019-01-15
EA201390323A1 (ru) 2013-09-30
PT2624833E (pt) 2014-12-26
PH12013500605B1 (en) 2018-07-04
SG189146A1 (en) 2013-05-31
US20230139808A1 (en) 2023-05-04
CA2813153A1 (en) 2012-04-12
AR083287A1 (es) 2013-02-13
AU2011313236B2 (en) 2016-05-19
CO6660459A2 (es) 2013-04-30
CN103189061B (zh) 2015-09-02
HK1187540A1 (en) 2014-04-11
SMT201500056B (it) 2015-05-05
MY157563A (en) 2016-06-30
JP5715690B2 (ja) 2015-05-13
WO2012046825A1 (en) 2012-04-12
EP2624833B1 (en) 2014-12-10
PL2624833T3 (pl) 2015-05-29
US20150105432A1 (en) 2015-04-16
KR101797797B1 (ko) 2017-11-14
BR112013007841B1 (pt) 2020-03-03
TW201307289A (zh) 2013-02-16
RS53749B1 (en) 2015-06-30
ZA201302332B (en) 2014-07-30
TWI526431B (zh) 2016-03-21
DK2624833T3 (en) 2015-01-05
JP2013538785A (ja) 2013-10-17
UA110037C2 (uk) 2015-11-10
NZ609151A (en) 2015-01-30
HRP20141237T1 (hr) 2015-02-13

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