SI2531527T1 - Monoklonsko protitelo proti CD44 za uporabo pri zdravljenju skvamoznoceličnega karcinoma glave in vratu - Google Patents
Monoklonsko protitelo proti CD44 za uporabo pri zdravljenju skvamoznoceličnega karcinoma glave in vratuInfo
- Publication number
- SI2531527T1 SI2531527T1 SI201130171T SI201130171T SI2531527T1 SI 2531527 T1 SI2531527 T1 SI 2531527T1 SI 201130171 T SI201130171 T SI 201130171T SI 201130171 T SI201130171 T SI 201130171T SI 2531527 T1 SI2531527 T1 SI 2531527T1
- Authority
- SI
- Slovenia
- Prior art keywords
- head
- treatment
- monoclonal antibody
- cell carcinoma
- squamous cell
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2884—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD44
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30144910P | 2010-02-04 | 2010-02-04 | |
PCT/EP2011/051436 WO2011095498A1 (en) | 2010-02-04 | 2011-02-02 | A monoclonal antibody to cd44 for use in the treatment of head and neck squamous cell carcinoma |
EP11703182.3A EP2531527B1 (en) | 2010-02-04 | 2011-02-02 | A monoclonal antibody to cd44 for use in the treatment of head and neck squamous cell carcinoma |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2531527T1 true SI2531527T1 (sl) | 2014-07-31 |
Family
ID=43858306
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201130171T SI2531527T1 (sl) | 2010-02-04 | 2011-02-02 | Monoklonsko protitelo proti CD44 za uporabo pri zdravljenju skvamoznoceličnega karcinoma glave in vratu |
Country Status (30)
Country | Link |
---|---|
US (2) | US20130224108A1 (sl) |
EP (1) | EP2531527B1 (sl) |
JP (2) | JP5763105B2 (sl) |
KR (1) | KR20130042466A (sl) |
CN (1) | CN102741292B (sl) |
AU (1) | AU2011212485B2 (sl) |
BR (1) | BR112012019475A8 (sl) |
CA (1) | CA2786337A1 (sl) |
CL (1) | CL2012001980A1 (sl) |
CR (1) | CR20120429A (sl) |
DK (1) | DK2531527T3 (sl) |
EC (1) | ECSP12012138A (sl) |
ES (1) | ES2460945T3 (sl) |
HR (1) | HRP20140513T1 (sl) |
IL (1) | IL220092A (sl) |
MA (1) | MA34010B1 (sl) |
MX (1) | MX2012008699A (sl) |
MY (1) | MY157532A (sl) |
NZ (1) | NZ600079A (sl) |
PE (1) | PE20130380A1 (sl) |
PH (1) | PH12012501525A1 (sl) |
PL (1) | PL2531527T3 (sl) |
PT (1) | PT2531527E (sl) |
RS (1) | RS53327B (sl) |
RU (1) | RU2599447C2 (sl) |
SG (2) | SG182704A1 (sl) |
SI (1) | SI2531527T1 (sl) |
TW (1) | TW201130512A (sl) |
WO (1) | WO2011095498A1 (sl) |
ZA (1) | ZA201205649B (sl) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA34010B1 (fr) * | 2010-02-04 | 2013-02-01 | Hoffmann La Roche | Anticorps monoclonal anti-cd44 destiné à être utilisé pour traiter le carcinome à cellules squameuses de la tête et du cou |
JP2014534221A (ja) * | 2011-10-26 | 2014-12-18 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | B細胞性慢性リンパ性白血病および他の血液悪性腫瘍の治療のためのcd44モノクローナル抗体 |
US20140335084A1 (en) * | 2011-12-06 | 2014-11-13 | Hoffmann-La Roche Inc. | Antibody formulation |
US20150044232A1 (en) * | 2013-06-12 | 2015-02-12 | Hoffmann-La Roche Inc. | Markers for the responsiveness to anti-cd44 antibodies |
KR102320503B1 (ko) * | 2013-07-31 | 2021-11-03 | 더 유니버시티 오브 마이애미 | 대상체에서 암 위험을 동정하는 조성물 및 방법 |
WO2015076425A1 (ja) * | 2013-11-25 | 2015-05-28 | リンク・ジェノミクス株式会社 | 新規モノクローナル抗体 |
KR102215384B1 (ko) * | 2014-06-11 | 2021-02-15 | (재) 스크립스코리아항체연구원 | CD44v3 도메인 3 및 도메인 6 특이적 단일클론 항체 및 그 용도 |
TWI535452B (zh) | 2015-01-23 | 2016-06-01 | 長庚醫療財團法人 | 使用抗-cd44中和抗體來治療和/或預防心房顫動 |
JP7212138B2 (ja) | 2018-07-20 | 2023-01-24 | ヨウキュア(ベイジン)バイオファーマ カンパニー リミテッド | 抗cd40抗体及びその使用 |
ES2988406T3 (es) | 2020-05-19 | 2024-11-20 | Inst Curie | Antagonistas de la ruta de CD44/ácido hialurónico para su uso en un método para el tratamiento del síndrome de liberación de citocinas |
EP4301782A1 (en) * | 2021-03-05 | 2024-01-10 | Go Therapeutics, Inc. | Anti-glyco-cd44 antibodies and their uses |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
UY24389A1 (es) * | 1995-12-06 | 2001-10-25 | Karlsruhe Forschzent | Composición farmacéutica para el tratamiento de carcinoma de epitelio plano |
DE19545472A1 (de) * | 1995-12-06 | 1997-06-12 | Boehringer Ingelheim Int | Verfahren zur Diagnose und Therapie von Plattenepithelkarzinomen |
US7252821B2 (en) | 1999-10-08 | 2007-08-07 | Arius Research Inc. | Cancerous disease modifying antibodies |
US8048416B2 (en) * | 1999-10-08 | 2011-11-01 | Hoffmann-La Roche Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US6180357B1 (en) | 1999-10-08 | 2001-01-30 | Arius Research, Inc. | Individualized patient-specific anti-cancer antibodies |
US20090004103A1 (en) * | 1999-10-08 | 2009-01-01 | Young David S F | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US20050100542A1 (en) | 1999-10-08 | 2005-05-12 | Young David S. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
US8071072B2 (en) * | 1999-10-08 | 2011-12-06 | Hoffmann-La Roche Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD44 |
MXPA03010523A (es) | 2001-05-18 | 2004-07-01 | Boehringer Ingelheim Pharma | Anticuerpos especificos para cd44v6. |
US20030103985A1 (en) | 2001-05-18 | 2003-06-05 | Boehringer Ingelheim International Gmbh | Cytotoxic CD44 antibody immunoconjugates |
AU2003272511A1 (en) * | 2002-09-13 | 2004-04-30 | Dyax Corporation | Cd44-binding ligands |
EP1532984A1 (en) * | 2003-11-19 | 2005-05-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Use of anti CD44 antibodies for eradicating stem cells in acute myeloid leukemia |
MA34010B1 (fr) * | 2010-02-04 | 2013-02-01 | Hoffmann La Roche | Anticorps monoclonal anti-cd44 destiné à être utilisé pour traiter le carcinome à cellules squameuses de la tête et du cou |
-
2011
- 2011-02-02 MA MA35156A patent/MA34010B1/fr unknown
- 2011-02-02 SG SG2012054847A patent/SG182704A1/en unknown
- 2011-02-02 KR KR1020127022586A patent/KR20130042466A/ko not_active Ceased
- 2011-02-02 CA CA2786337A patent/CA2786337A1/en not_active Abandoned
- 2011-02-02 PT PT117031823T patent/PT2531527E/pt unknown
- 2011-02-02 SG SG10201505118PA patent/SG10201505118PA/en unknown
- 2011-02-02 PH PH1/2012/501525A patent/PH12012501525A1/en unknown
- 2011-02-02 MY MYPI2012003179A patent/MY157532A/en unknown
- 2011-02-02 WO PCT/EP2011/051436 patent/WO2011095498A1/en active Application Filing
- 2011-02-02 DK DK11703182.3T patent/DK2531527T3/da active
- 2011-02-02 ES ES11703182.3T patent/ES2460945T3/es active Active
- 2011-02-02 CN CN201180008111.1A patent/CN102741292B/zh not_active Expired - Fee Related
- 2011-02-02 AU AU2011212485A patent/AU2011212485B2/en not_active Ceased
- 2011-02-02 PE PE2012001162A patent/PE20130380A1/es not_active Application Discontinuation
- 2011-02-02 EP EP11703182.3A patent/EP2531527B1/en not_active Not-in-force
- 2011-02-02 RU RU2012137380/10A patent/RU2599447C2/ru not_active IP Right Cessation
- 2011-02-02 PL PL11703182T patent/PL2531527T3/pl unknown
- 2011-02-02 RS RS20140251A patent/RS53327B/en unknown
- 2011-02-02 SI SI201130171T patent/SI2531527T1/sl unknown
- 2011-02-02 NZ NZ600079A patent/NZ600079A/xx not_active IP Right Cessation
- 2011-02-02 MX MX2012008699A patent/MX2012008699A/es active IP Right Grant
- 2011-02-02 JP JP2012551602A patent/JP5763105B2/ja not_active Expired - Fee Related
- 2011-02-02 BR BR112012019475A patent/BR112012019475A8/pt not_active IP Right Cessation
- 2011-02-04 US US13/021,442 patent/US20130224108A1/en not_active Abandoned
- 2011-02-08 TW TW100104223A patent/TW201130512A/zh unknown
-
2012
- 2012-05-31 IL IL220092A patent/IL220092A/en not_active IP Right Cessation
- 2012-07-17 CL CL2012001980A patent/CL2012001980A1/es unknown
- 2012-07-26 ZA ZA2012/05649A patent/ZA201205649B/en unknown
- 2012-08-17 CR CR20120429A patent/CR20120429A/es unknown
- 2012-09-04 EC ECSP12012138 patent/ECSP12012138A/es unknown
-
2014
- 2014-06-03 HR HRP20140513AT patent/HRP20140513T1/hr unknown
-
2015
- 2015-02-27 JP JP2015038519A patent/JP6037149B2/ja not_active Expired - Fee Related
- 2015-09-03 US US14/845,134 patent/US20150374848A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL220092A0 (en) | A monoclonal antibody to cd44 for use in the treatment of head and neck squamous cell carcinoma | |
IL231282A0 (en) | Antibodies to 9pcsk and their uses | |
EP2814509A4 (en) | ANTIBODY AGAINST INTEGRIN V6 AND USE THEREOF FOR THE TREATMENT OF CANCER | |
HUE043355T2 (hu) | LIV-1 elleni humanizált antitestek és alkalmazásuk a rák kezelésében | |
HK1211959A1 (en) | Antibodies to quetiapine haptens and use thereof | |
HK1212035A1 (en) | Antibodies to quetiapine and use thereof | |
EP2874650A4 (en) | FOR CD22 SPECIFIC ANTIBODIES AND METHOD FOR USE THEREOF | |
IL232556A0 (en) | Methods for detecting human papillomavirus and providing a diagnosis for squamous cell carcinoma of the head and neck | |
EP2888277A4 (en) | ANTIBODIES AGAINST PALIPERIDONE AND USE THEREOF | |
HRP20190289T1 (hr) | Protutijela protiv antigena specifičnog za matične stanice prostate i njihova upotreba | |
IL227687B (en) | Anti-alpha-v integrin antibody for use in the treatment of prostate cancer | |
PL2799445T3 (pl) | Polipeptyd blokujący integrynę do zastosowania w leczeniu reumatoidalnego zapalenia stawów | |
GB201215254D0 (en) | Improvements in or relating to closures and containers necks | |
HK1201856A1 (en) | Antibody specific to profilaggrin -terminal domain, and use thereof | |
HK1197037A1 (en) | Composition to be applied to the skin, and use thereof | |
GB201110302D0 (en) | Improvements in and relating to the consideration of evidence | |
GB201110959D0 (en) | Improvements in or relating to closures | |
GB201110063D0 (en) | Improvements to liquid bottles and combined applicators | |
GB201110064D0 (en) | Improvements to liquid rollerball and combined applicators |