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SI2125792T1 - Purinski derivati kot imunomodulatorji - Google Patents

Purinski derivati kot imunomodulatorji

Info

Publication number
SI2125792T1
SI2125792T1 SI200830160T SI200830160T SI2125792T1 SI 2125792 T1 SI2125792 T1 SI 2125792T1 SI 200830160 T SI200830160 T SI 200830160T SI 200830160 T SI200830160 T SI 200830160T SI 2125792 T1 SI2125792 T1 SI 2125792T1
Authority
SI
Slovenia
Prior art keywords
immunomodulators
purine derivatives
purine
derivatives
Prior art date
Application number
SI200830160T
Other languages
English (en)
Inventor
Linos Lazarides
Stephen Allan Smith
Richard Stocker
Colin Jack Theobald
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of SI2125792T1 publication Critical patent/SI2125792T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
SI200830160T 2007-02-19 2008-02-15 Purinski derivati kot imunomodulatorji SI2125792T1 (sl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US89052307P 2007-02-19 2007-02-19
US97231307P 2007-09-14 2007-09-14
US2192108P 2008-01-18 2008-01-18
EP08716859A EP2125792B1 (en) 2007-02-19 2008-02-15 Purine derivatives as immunomodulators
PCT/EP2008/051832 WO2008101867A1 (en) 2007-02-19 2008-02-15 Purine derivatives as immunomodulators

Publications (1)

Publication Number Publication Date
SI2125792T1 true SI2125792T1 (sl) 2011-03-31

Family

ID=39473324

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200830160T SI2125792T1 (sl) 2007-02-19 2008-02-15 Purinski derivati kot imunomodulatorji

Country Status (15)

Country Link
US (4) US7977344B2 (sl)
EP (1) EP2125792B1 (sl)
JP (1) JP2010519186A (sl)
AR (1) AR065372A1 (sl)
AT (1) ATE490249T1 (sl)
CL (1) CL2008000496A1 (sl)
CY (1) CY1111281T1 (sl)
DE (1) DE602008003764D1 (sl)
DK (1) DK2125792T3 (sl)
HR (1) HRP20110115T1 (sl)
PL (1) PL2125792T3 (sl)
PT (1) PT2125792E (sl)
SI (1) SI2125792T1 (sl)
TW (1) TW200843779A (sl)
WO (1) WO2008101867A1 (sl)

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JP5329444B2 (ja) * 2007-03-19 2013-10-30 アストラゼネカ・アクチエボラーグ Ｔｏｌｌ様受容体（ｔｌｒ７）モジュレーターとしての９−置換−８−オキソ−アデニン化合物
US8067413B2 (en) * 2007-03-19 2011-11-29 Astrazeneca Ab 9-substituted-8-oxo-adenine compounds as toll-like receptor (TLR7 ) modulators
PE20081887A1 (es) * 2007-03-20 2009-01-16 Dainippon Sumitomo Pharma Co Nuevo compuesto de adenina
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Also Published As

Publication number Publication date
JP2010519186A (ja) 2010-06-03
AR065372A1 (es) 2009-06-03
US20110269781A1 (en) 2011-11-03
WO2008101867A1 (en) 2008-08-28
US20100120799A1 (en) 2010-05-13
DE602008003764D1 (de) 2011-01-13
US20120283438A1 (en) 2012-11-08
DK2125792T3 (da) 2011-03-07
HRP20110115T1 (hr) 2011-03-31
EP2125792B1 (en) 2010-12-01
PL2125792T3 (pl) 2011-05-31
PT2125792E (pt) 2011-03-01
US7977344B2 (en) 2011-07-12
ATE490249T1 (de) 2010-12-15
US20090131458A1 (en) 2009-05-21
CL2008000496A1 (es) 2008-09-22
TW200843779A (en) 2008-11-16
EP2125792A1 (en) 2009-12-02
CY1111281T1 (el) 2015-08-05

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