[go: up one dir, main page]

SI1284978T2 - Postopek äśiĺ äśenja soli klavulanske kisline - Google Patents

Postopek äśiĺ äśenja soli klavulanske kisline

Info

Publication number
SI1284978T2
SI1284978T2 SI200130207T SI200130207T SI1284978T2 SI 1284978 T2 SI1284978 T2 SI 1284978T2 SI 200130207 T SI200130207 T SI 200130207T SI 200130207 T SI200130207 T SI 200130207T SI 1284978 T2 SI1284978 T2 SI 1284978T2
Authority
SI
Slovenia
Prior art keywords
salt
clavulanic acid
purification
exposed
typically
Prior art date
Application number
SI200130207T
Other languages
English (en)
Other versions
SI1284978T1 (sl
Inventor
Guo Zhang
John Mcknight
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26244256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1284978(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0011521A external-priority patent/GB0011521D0/en
Priority claimed from GB0011519A external-priority patent/GB0011519D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of SI1284978T1 publication Critical patent/SI1284978T1/sl
Publication of SI1284978T2 publication Critical patent/SI1284978T2/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
SI200130207T 2000-05-13 2001-05-09 Postopek äśiĺ äśenja soli klavulanske kisline SI1284978T2 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0011521A GB0011521D0 (en) 2000-05-13 2000-05-13 Process
GB0011519A GB0011519D0 (en) 2000-05-13 2000-05-13 Process
EP01925753A EP1284978B2 (en) 2000-05-13 2001-05-09 Process for the purification of a salt of clavulanic acid
PCT/GB2001/002025 WO2001087891A1 (en) 2000-05-13 2001-05-09 Process for the purification of a salt of clavulanic acid

Publications (2)

Publication Number Publication Date
SI1284978T1 SI1284978T1 (sl) 2005-02-28
SI1284978T2 true SI1284978T2 (sl) 2008-12-31

Family

ID=26244256

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200130207T SI1284978T2 (sl) 2000-05-13 2001-05-09 Postopek äśiĺ äśenja soli klavulanske kisline

Country Status (24)

Country Link
US (1) US7767823B2 (sl)
EP (1) EP1284978B2 (sl)
JP (1) JP4954421B2 (sl)
KR (1) KR100827898B1 (sl)
CN (1) CN1222528C (sl)
AT (1) ATE273982T1 (sl)
AU (1) AU776184B2 (sl)
BR (1) BRPI0110774B8 (sl)
CA (1) CA2408853C (sl)
CZ (1) CZ304775B6 (sl)
DE (1) DE60105016T3 (sl)
DK (1) DK1284978T4 (sl)
ES (1) ES2225524T5 (sl)
HK (1) HK1055111A1 (sl)
HU (1) HU228593B1 (sl)
IL (2) IL152643A0 (sl)
MX (1) MXPA02011192A (sl)
NO (1) NO328528B1 (sl)
NZ (1) NZ522414A (sl)
PL (1) PL206316B1 (sl)
PT (1) PT1284978E (sl)
SI (1) SI1284978T2 (sl)
WO (1) WO2001087891A1 (sl)
ZA (1) ZA200209141B (sl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2225524T5 (es) 2000-05-13 2009-03-01 Smithkline Beecham Plc Procedimiento para la purificacion de una sal de acido clavulanico.
CN105384758B (zh) * 2015-12-01 2018-05-01 国药集团威奇达药业有限公司 克拉维酸胺盐的制备方法
AU2017295866A1 (en) 2016-07-14 2019-01-17 Achaogen, Inc. Combination of ceftibuten and clavulanic acid for use in the treatment of bacterial infections
CN109305978A (zh) * 2017-07-26 2019-02-05 山东睿鹰先锋制药有限公司 一种制备克拉维酸盐的新方法
CN109535184B (zh) * 2017-09-21 2020-11-20 联邦制药(内蒙古)有限公司 一种克拉维酸叔辛胺制备克拉维酸钾的方法
CN108558909B (zh) * 2018-05-17 2019-09-17 国药集团威奇达药业有限公司 综合回收克拉维酸叔丁胺盐结晶母液中有效成分的方法
EP3994154A1 (en) 2019-07-05 2022-05-11 GlaxoSmithKline Intellectual Property (No.2) Limited Streptomyces clavuligerus

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1299883A (fr) 1961-09-06 1962-07-27 Pfizer & Co C Perfectionnements apportés aux procédés pour séparer des amino-acides amphotères de leurs solutions aqueuses
GB1508977A (en) 1974-04-20 1978-04-26 Beecham Group Ltd Beta-lactam antibiotic from streptomyces clavuligerus
GB2003863B (en) 1977-09-01 1982-03-31 Beecham Group Ltd Chemical process
DE3063683D1 (en) 1979-08-24 1983-07-14 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
US4449182A (en) * 1981-10-05 1984-05-15 Digital Equipment Corporation Interface between a pair of processors, such as host and peripheral-controlling processors in data processing systems
MX7417E (es) 1984-10-27 1988-10-14 Antibioticos Sa Metodo para la preparacion de acido clavulanico y sus derivados
AT399154B (de) 1987-01-29 1995-03-27 Beecham Group Plc Neue kristalline form von kaliumclavulanat
GB2204944B (en) 1987-05-18 1991-10-02 Frederick John Anderson Rechargeable light
DE3729338A1 (de) 1987-09-02 1989-03-23 Biotechnolog Forschung Gmbh Verfahren zur abtrennung von penicillin g aus einem fermentationsmedium durch extraktion
US5318896A (en) 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
RO116648B1 (ro) 1991-10-15 2001-04-30 Merck & Co Inc Bioprocedeu pentru prepararea acidului 7-amino-3-deacetil-cefalosporanic si a acidului 7-aminocefalosporanic
AT400033B (de) * 1992-03-10 1995-09-25 Biochemie Gmbh Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
SI9300296B (sl) 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
KR100200239B1 (ko) * 1992-10-21 1999-06-15 김충환 클라불란산 칼륨염의 제조방법
GB9305565D0 (en) 1993-03-18 1993-05-05 Smithkline Beecham Plc Novel compounds and processes
US5821364A (en) * 1993-03-26 1998-10-13 Gist-Brocades N.V. Diamine salts of clavulanic acid
KR100336174B1 (ko) 1993-07-30 2002-11-01 디에스엠 기스트 베.파우. 2-(카르복시에틸티오)아세틸-7-adca및3-(카르복시메틸티오)프로피오닐-7-adca를경유하여7-adca를제조하는효율적인방법
AT400846B (de) 1994-02-25 1996-03-25 Fermic S A De C V Verfahren zur gewinnung und reinigung von alkalimetallsalzen der clavulansäure
SI9400107A (en) 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
SI9500074A (en) 1995-03-10 1996-10-31 Lek Tovarna Farmacevtskih Process for preparation of alkani salts of clavulanic acid.
SI9500134B (sl) 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
KR100200242B1 (ko) 1995-05-16 1999-06-15 김충환 클라불란산염의 제조 방법
WO1997005143A1 (fr) * 1995-07-25 1997-02-13 Asahi Kasei Kogyo Kabushiki Kaisha Nouveaux composes a base de metaux de transition du groupe 4
GB9515809D0 (en) * 1995-08-02 1995-10-04 Smithkline Beecham Plc Process
JP2001503763A (ja) * 1996-11-11 2001-03-21 ギスト ブロカデス ベスローテン フェンノートシャップ クラバラン酸の塩及びエステルの調製法
AT404728B (de) * 1996-11-27 1999-02-25 Biochemie Gmbh Verfahren zur herstellung von clavulansäure-aminsalzen
WO1998042858A1 (en) * 1997-03-24 1998-10-01 Cipan-Companhia Industrial Produtora De Antibióticos, S.A. Process for the isolation of a pharmaceutically acceptable alkali metal salt of clavulanic acid
US6319684B1 (en) 1997-04-22 2001-11-20 Dms N.V. Process for the fermentative production of cephalosporin
AU5411099A (en) * 1998-07-16 2000-02-07 Dsm N.V. Improved process for the preparation of salts and esters of clavulanic acid
ES2225524T5 (es) 2000-05-13 2009-03-01 Smithkline Beecham Plc Procedimiento para la purificacion de una sal de acido clavulanico.

Also Published As

Publication number Publication date
SI1284978T1 (sl) 2005-02-28
ZA200209141B (en) 2003-12-31
WO2001087891A1 (en) 2001-11-22
HUP0300869A2 (hu) 2003-08-28
EP1284978B1 (en) 2004-08-18
JP4954421B2 (ja) 2012-06-13
DK1284978T3 (da) 2004-12-13
HUP0300869A3 (en) 2003-10-28
AU776184B2 (en) 2004-09-02
KR100827898B1 (ko) 2008-05-07
PT1284978E (pt) 2004-12-31
NO328528B1 (no) 2010-03-08
DE60105016T2 (de) 2005-08-18
ES2225524T5 (es) 2009-03-01
PL206316B1 (pl) 2010-07-30
US7767823B2 (en) 2010-08-03
EP1284978B2 (en) 2008-09-10
DE60105016D1 (de) 2004-09-23
CN1429227A (zh) 2003-07-09
CN1222528C (zh) 2005-10-12
DE60105016T3 (de) 2009-06-25
NO20025422L (no) 2003-01-07
NO20025422D0 (no) 2002-11-12
EP1284978A1 (en) 2003-02-26
CA2408853A1 (en) 2001-11-22
DK1284978T4 (da) 2009-01-05
IL152643A0 (en) 2003-06-24
KR20030014222A (ko) 2003-02-15
MXPA02011192A (es) 2003-03-10
ES2225524T3 (es) 2005-03-16
BRPI0110774B8 (pt) 2021-05-25
JP2003533529A (ja) 2003-11-11
HU228593B1 (en) 2013-04-29
PL358368A1 (en) 2004-08-09
US20060079676A1 (en) 2006-04-13
HK1055111A1 (en) 2003-12-24
CZ304775B6 (cs) 2014-10-15
BRPI0110774B1 (pt) 2015-07-07
ATE273982T1 (de) 2004-09-15
CA2408853C (en) 2012-01-10
AU5243201A (en) 2001-11-26
NZ522414A (en) 2004-05-28
CZ20023723A3 (cs) 2003-05-14
IL152643A (en) 2012-12-31
BR0110774A (pt) 2003-05-13

Similar Documents

Publication Publication Date Title
NZ515561A (en) Method for the production of thiazolidin
EP1048694A4 (en) AZO COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
ES2068000T3 (es) Separacion de metales de peroxiacidos o peroxisales acuosos.
AU4213896A (en) Process for purifying water
IL152643A0 (en) Process for the purification of a salt of clavulanic acid
CA2425615A1 (en) Process for the purification of gabapentin using a strong cation exchange resin
SG48415A1 (en) Process for the purification of a 3-cephem-4-carboxylic acid derivative
MY112976A (en) Process for purifying valine
HU9802586D0 (en) Racemizing process
FR2780968B1 (fr) Procede de preparation de l'acide hydroxymethylthiobutyrique
GR3029438T3 (en) Block detergent containing nitrilotriacetic acid
IL110566A0 (en) Stable aqueous solutions of hybrid alpha-interferon
MXPA01011846A (es) Proceso para purificar soluciones acuosas de amina y alcanolamina terciarias.
MXPA03005676A (es) Formas de dosis solidas de sodio de divalproex.
MXPA98008451A (es) Proceso para el retiro de cianuro y especies de metal pesado, toxicos a partir de soluciones alcalinas.
AU2166201A (en) A process for the recovery of copper from aqueous solutions containing iodinatedorganic compounds
TWI256943B (en) Production method for aluminum sulfate, aluminum sulfate, method for improving for improving yield of aluminum sulfate, use of nitric acid, industrial composition, method for processing waste water, and device for processing waste water
ID28039A (id) Proses untuk berturut-turut memproses ulang pemurnian larutan-larutan berair dari suatu amina oksida tersier
IT1309601B1 (it) Processo per la preparazione di 1,4,7,10 tetraazaciclododecano.
DK0647205T3 (da) Fremgangsmåde til oprensning af phosphorsyre
MY134147A (en) Method for stoping hysteresis
CA2150212A1 (en) Aqueous composition useful in ore flotation containing aliphatic amine
ES8302120A1 (es) Un procedimiento para limpiar una superficie de estano con el fin de eliminar desde ella lubricantes u otros contaminan-tes.
GR970100090A (el) Διαδικασια παραγωγης 1,2-διμεθυλ-3-υδροξυπυριδ-4-ονης
MXPA03001712A (es) Proceso para la preparacion de un nucleo de beta-lactama y aplicacion del mismo.