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SI0975347T1 - Sinergistična kombinacija PDE inhibitorjev in agonistov adenilat ciklaze oziroma agonistov gvanil ciklize - Google Patents

Sinergistična kombinacija PDE inhibitorjev in agonistov adenilat ciklaze oziroma agonistov gvanil ciklize

Info

Publication number
SI0975347T1
SI0975347T1 SI9830909T SI9830909T SI0975347T1 SI 0975347 T1 SI0975347 T1 SI 0975347T1 SI 9830909 T SI9830909 T SI 9830909T SI 9830909 T SI9830909 T SI 9830909T SI 0975347 T1 SI0975347 T1 SI 0975347T1
Authority
SI
Slovenia
Prior art keywords
agonists
adenylate cyclase
cyclyse
guanyl
synergistic combination
Prior art date
Application number
SI9830909T
Other languages
English (en)
Inventor
Rolf Beume
Dieter Flockerzi
Klaus-Dieter Beller
Friedrich Grimminger
Norbert Suttorp
Christian Schudt
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of SI0975347T1 publication Critical patent/SI0975347T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI9830909T 1997-02-28 1998-02-24 Sinergistična kombinacija PDE inhibitorjev in agonistov adenilat ciklaze oziroma agonistov gvanil ciklize SI0975347T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19708049 1997-02-28
PCT/EP1998/001047 WO1998037894A1 (de) 1997-02-28 1998-02-24 Synergistische kombination von pde-hemmern und adenylatcyclase-agonisten bzw. guanylcyclyse-agonisten
EP98913584A EP0975347B1 (de) 1997-02-28 1998-02-24 Synergistische kombination von pde-hemmern und adenylatcyclase-agonisten bzw. guanylcyclyse-agonisten

Publications (1)

Publication Number Publication Date
SI0975347T1 true SI0975347T1 (sl) 2008-08-31

Family

ID=7821764

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830909T SI0975347T1 (sl) 1997-02-28 1998-02-24 Sinergistična kombinacija PDE inhibitorjev in agonistov adenilat ciklaze oziroma agonistov gvanil ciklize

Country Status (12)

Country Link
US (1) US6333354B1 (sl)
EP (1) EP0975347B1 (sl)
JP (2) JP2001513097A (sl)
AT (1) ATE386531T1 (sl)
AU (1) AU6823098A (sl)
CY (1) CY2607B2 (sl)
DE (1) DE59814173D1 (sl)
DK (1) DK0975347T3 (sl)
ES (1) ES2302350T3 (sl)
PT (1) PT975347E (sl)
SI (1) SI0975347T1 (sl)
WO (1) WO1998037894A1 (sl)

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US7208516B2 (en) * 2002-03-20 2007-04-24 Celgene Corporation Methods of the treatment of psoriatic arthritis using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
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EA009935B1 (ru) * 2002-11-27 2008-04-28 Никомед Гмбх Новая синергетическая комбинация, включающая рофлумиласт и формотерол
SI1567140T1 (sl) * 2002-11-27 2008-12-31 Nycomed Gmbh Sinergistična kombinacija, ki obsega roflumilastin (R;R)-formoterol
US20060083714A1 (en) * 2003-01-27 2006-04-20 Warner James M Combination of a pde iv inhibitor and a tnf-alpha antagonist
RU2543350C2 (ru) 2003-01-28 2015-02-27 Айронвуд Фармасьютикалз, Инк. Способы и композиции для лечения желудочно-кишечных расстройств
EP1620083A2 (en) * 2003-04-18 2006-02-01 Pharmacia & Upjohn Company LLC Combination therapies
ES2433661T3 (es) 2005-04-19 2013-12-12 Takeda Gmbh Roflumilast para el tratamiento de hipertensión pulmonar
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
AU2006282896A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
WO2007047978A2 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by pde inhibition
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
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JP2011515469A (ja) * 2008-03-24 2011-05-19 セルジーン コーポレイション シクロプロピル−n−{2−[(1s)−1−(3−エトキシ−4−メトキシフェニル)−2−(メチルスルホニル)エチル]−3−オキソイソインドリン−4−イル}カルボキサミドを使用した乾癬又は乾癬性関節炎の治療
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US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
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Also Published As

Publication number Publication date
ATE386531T1 (de) 2008-03-15
WO1998037894A1 (de) 1998-09-03
EP0975347B1 (de) 2008-02-20
DE59814173D1 (de) 2008-04-03
AU6823098A (en) 1998-09-18
JP2009073853A (ja) 2009-04-09
EP0975347A1 (de) 2000-02-02
PT975347E (pt) 2008-05-23
ES2302350T3 (es) 2008-07-01
JP2001513097A (ja) 2001-08-28
US6333354B1 (en) 2001-12-25
CY2607B2 (en) 2010-04-28
DK0975347T3 (da) 2008-06-16

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