SG46281A1 - Piperazine derivatives - Google Patents
Piperazine derivativesInfo
- Publication number
- SG46281A1 SG46281A1 SG1996002067A SG1996002067A SG46281A1 SG 46281 A1 SG46281 A1 SG 46281A1 SG 1996002067 A SG1996002067 A SG 1996002067A SG 1996002067 A SG1996002067 A SG 1996002067A SG 46281 A1 SG46281 A1 SG 46281A1
- Authority
- SG
- Singapore
- Prior art keywords
- piperazine derivatives
- piperazine
- derivatives
- Prior art date
Links
- 150000004885 piperazines Chemical class 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT93MI001717A IT1266582B1 (en) | 1993-07-30 | 1993-07-30 | (DI) AZACYLO-HEXANIC AND DIAZACYLO-HEPTANIC DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG46281A1 true SG46281A1 (en) | 1998-02-20 |
Family
ID=11366733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG1996002067A SG46281A1 (en) | 1993-07-30 | 1994-07-22 | Piperazine derivatives |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0711288A1 (en) |
| JP (1) | JPH09500883A (en) |
| KR (1) | KR960703884A (en) |
| CN (1) | CN1132508A (en) |
| AU (1) | AU680037B2 (en) |
| CA (1) | CA2168443A1 (en) |
| IL (1) | IL110348A0 (en) |
| IT (1) | IT1266582B1 (en) |
| MX (1) | MXPA94005805A (en) |
| NO (1) | NO960371L (en) |
| NZ (1) | NZ271634A (en) |
| SG (1) | SG46281A1 (en) |
| WO (1) | WO1995004049A1 (en) |
| ZA (1) | ZA945625B (en) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5661163A (en) * | 1995-06-07 | 1997-08-26 | Merck & Co., Inc. | Alpha-1a adrenergic receptor antagonists |
| US5620993A (en) * | 1995-06-07 | 1997-04-15 | Merck & Co., Inc. | Alpha-1a adrenergic receptor antagonists |
| US5659033A (en) * | 1995-09-13 | 1997-08-19 | Neurogen Corporation | N-aminoalkylfluorenecarboxamides; a new class of dopamine receptor subtype specific ligands |
| US5807856A (en) * | 1995-11-15 | 1998-09-15 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonist |
| WO1997019068A1 (en) * | 1995-11-17 | 1997-05-29 | Warner-Lambert Company | Sulfonamide inhibitors of matrix metalloproteinases |
| IL124436A0 (en) | 1995-12-29 | 1998-12-06 | Boehringer Ingelheim Phaarmace | Phenyl thiazole derivatives with anti herpes virus properties |
| US6288091B1 (en) | 1995-12-29 | 2001-09-11 | Boehringer Ingelheim Ltd. | Antiherpes virus compounds and methods for their preparation and use |
| DE69717978T2 (en) * | 1996-04-05 | 2003-10-02 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.), Paris | ALPHA-1 ADRENERGIC RECEPTOR ANTAGONISTS |
| JP4150435B2 (en) * | 1996-04-18 | 2008-09-17 | 株式会社資生堂 | Alkylene diamine derivatives and anti-ulcer agents, antibacterial agents |
| US6211215B1 (en) | 1996-07-19 | 2001-04-03 | Takeda Chemical Industries, Ltd. | Heterocyclic compounds, their production and use |
| ES2206928T3 (en) | 1997-05-12 | 2004-05-16 | Ortho-Mcneil Pharmaceutical, Inc. | PIPERACINAS REPLACED WITH ARILO USEFUL IN THE TREATMENT OF BENIGNA HYPERPLASIA DE PROSTATA. |
| AU2002300904B2 (en) * | 1997-05-12 | 2004-12-23 | Ortho-Mcneil Pharmaceutical, Inc. | Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia |
| EP1000045A1 (en) * | 1997-08-01 | 2000-05-17 | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY | 1,4-disubstituted piperazines |
| IT1293804B1 (en) | 1997-08-01 | 1999-03-10 | Recordati Chem Pharm | DIARYLALKYL PIPERAZINS ACTIVE ON LOW URINARY TRACT |
| IT1293807B1 (en) * | 1997-08-01 | 1999-03-10 | Recordati Chem Pharm | 1- (N-PHENYLAMINOALKYL) PIPERAZINE DERIVATIVES SUBSTITUTED AT POSITION 2 OF THE PHENYL RING |
| US6271234B1 (en) | 1997-08-01 | 2001-08-07 | Recordati S.A., Chemical And Pharmaceutical Company | 1,4-disubstituted piperazines |
| US6399614B1 (en) | 1997-08-01 | 2002-06-04 | Recordati S.A. Chemical And Pharmaceutical Company | 1-(N-phenylaminoalkyl)piperazine derivatives substituted at position 2 of the phenyl ring |
| US6218396B1 (en) * | 1998-02-20 | 2001-04-17 | Orth-Mcneil Pharmaceutical, Inc. | Substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia |
| AU5467699A (en) | 1998-08-07 | 2000-02-28 | Chiron Corporation | Substituted isoxazole as estrogen receptor modulators |
| US6365591B1 (en) | 1999-10-18 | 2002-04-02 | Recordati, S.A., Chemical And Pharmacueticals Company | Isoxazolecarboxamide derivatives |
| IT1314191B1 (en) * | 1999-10-18 | 2002-12-06 | Recordati Chem Pharm | ISOSSAZOLCARBOSSAMIDIC DERIVATIVES |
| AR027133A1 (en) * | 1999-12-30 | 2003-03-12 | Lundbeck & Co As H | DERIVATIVES OF HETEROARILO, ITS PREPARATION AND USE. |
| JP3940290B2 (en) * | 2000-12-22 | 2007-07-04 | ザ・ヨルダニアン・フアーマシユーテイカル・エム・エフ・ジー・アンド・メデイカル・イクイツプメント・カンパニー・リミテツド | New compounds |
| SE0004780D0 (en) | 2000-12-22 | 2000-12-22 | Jordanian Pharmaceutical Mfg & | Novel compunds |
| EP1351936A1 (en) * | 2001-01-15 | 2003-10-15 | Glaxo Group Limited | Aryl piperidine and piperazine derivatives as inducers of ldl-receptor expression |
| US7153858B2 (en) | 2003-01-31 | 2006-12-26 | Epix Delaware, Inc. | Arylpiperazinyl compounds |
| US8394954B2 (en) * | 2007-03-30 | 2013-03-12 | Council Of Scientific & Industrial Research | Benzophenone hybrids as anticancer agents and processes for the preparation thereof |
| JP4827986B2 (en) | 2007-06-08 | 2011-11-30 | マンカインド コーポレ−ション | IRE-1α inhibitor |
| CN104860907A (en) | 2010-06-07 | 2015-08-26 | 诺沃梅迪科斯有限公司 | Furanyl compounds and the use thereof |
| WO2013086496A2 (en) | 2011-12-09 | 2013-06-13 | Research Triangle Institute | 1-substituted 4-arylpiperazine as kappa opioid receptor antagonists |
| BR102012000187A2 (en) * | 2012-01-05 | 2018-04-10 | Univ Rio De Janeiro | N-phenylpiperazine derivatives a1a, a1d and 5-ht1a receptor antagonist antagonists in the treatment of benign prostatic hyperplasia, pharmaceutical compositions containing the same |
| WO2023044364A1 (en) | 2021-09-15 | 2023-03-23 | Enko Chem, Inc. | Protoporphyrinogen oxidase inhibitors |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2997472A (en) * | 1961-08-22 | Certificate of correction | ||
| FR6452M (en) * | 1967-03-10 | 1968-11-12 | ||
| FR1543944A (en) * | 1967-03-10 | 1968-10-31 | Bruneau & Cie Lab | Salicylic acid amide derivatives and their preparation |
| US3557107A (en) * | 1967-05-01 | 1971-01-19 | Shulton Inc | Phenylpiperazinylalkyl alkoxy anthranilates |
| FR1537901A (en) * | 1967-07-19 | 1968-08-30 | Bruneau & Cie Lab | Amide derivatives of halogeno and nitro benzoic acids and their preparation |
| FR6924M (en) * | 1967-10-18 | 1969-05-05 | ||
| US3846430A (en) * | 1968-01-12 | 1974-11-05 | Bruneau & Cie Lab | 1-(2-methoxy-phenyl)-4-{8 2-(4-fluoro-benzamido)-ethyl{9 -piperazine |
| NL8005133A (en) * | 1980-09-12 | 1982-04-01 | Duphar Int Res | PHENYLPIPERAZINE DERIVATIVES WITH ANTIAGRESSIVE ACTION. |
| US4642291A (en) * | 1982-09-01 | 1987-02-10 | Sloan-Kettering Institute For Cancer Research | Cell surface antigens of human astrocytoma |
| JPS5955878A (en) * | 1982-09-24 | 1984-03-31 | Chugai Pharmaceut Co Ltd | Novel phenylpiperazine derivative |
| JPS60169467A (en) * | 1984-02-10 | 1985-09-02 | Chugai Pharmaceut Co Ltd | Novel phenylpiperazine derivative |
| JP2556722B2 (en) * | 1988-02-18 | 1996-11-20 | 興和株式会社 | Novel sulfonamide compound |
| US4857644A (en) * | 1988-06-09 | 1989-08-15 | American Home Products Corporation | Aryl sulfonopiperazines as anti-inflammatory agents |
| ES2027898A6 (en) * | 1991-01-24 | 1992-06-16 | Espanola Prod Quimicos | 2-Methoxyphenylpiperazine derivatives. |
| SG65570A1 (en) * | 1992-02-25 | 1999-06-22 | Recordati Chem Pharm | Heterobicyclic compounds |
| SE9201138D0 (en) * | 1992-04-09 | 1992-04-09 | Astra Ab | NOVEL PHTHALIMIDOALKYL PIPERAZINES |
-
1993
- 1993-07-30 IT IT93MI001717A patent/IT1266582B1/en active IP Right Grant
-
1994
- 1994-07-18 IL IL11034894A patent/IL110348A0/en unknown
- 1994-07-22 WO PCT/EP1994/002437 patent/WO1995004049A1/en not_active Application Discontinuation
- 1994-07-22 EP EP94925382A patent/EP0711288A1/en not_active Withdrawn
- 1994-07-22 SG SG1996002067A patent/SG46281A1/en unknown
- 1994-07-22 NZ NZ271634A patent/NZ271634A/en unknown
- 1994-07-22 CA CA002168443A patent/CA2168443A1/en not_active Abandoned
- 1994-07-22 AU AU75323/94A patent/AU680037B2/en not_active Ceased
- 1994-07-22 CN CN94193622A patent/CN1132508A/en active Pending
- 1994-07-22 KR KR1019960700460A patent/KR960703884A/en not_active Application Discontinuation
- 1994-07-22 JP JP7505546A patent/JPH09500883A/en active Pending
- 1994-07-29 MX MXPA94005805A patent/MXPA94005805A/en unknown
- 1994-07-29 ZA ZA945625A patent/ZA945625B/en unknown
-
1996
- 1996-01-29 NO NO960371A patent/NO960371L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL110348A0 (en) | 1994-10-21 |
| ZA945625B (en) | 1995-03-07 |
| IT1266582B1 (en) | 1997-01-09 |
| NO960371L (en) | 1996-03-29 |
| ITMI931717A0 (en) | 1993-07-30 |
| JPH09500883A (en) | 1997-01-28 |
| MXPA94005805A (en) | 2004-08-20 |
| AU680037B2 (en) | 1997-07-17 |
| WO1995004049A1 (en) | 1995-02-09 |
| KR960703884A (en) | 1996-08-31 |
| EP0711288A1 (en) | 1996-05-15 |
| CA2168443A1 (en) | 1995-02-09 |
| AU7532394A (en) | 1995-02-28 |
| NZ271634A (en) | 1996-09-25 |
| ITMI931717A1 (en) | 1995-01-30 |
| CN1132508A (en) | 1996-10-02 |
| NO960371D0 (en) | 1996-01-29 |
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