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SG11202110137VA - Benzodiazepine derivatives as rsv inhibitors - Google Patents

Benzodiazepine derivatives as rsv inhibitors

Info

Publication number
SG11202110137VA
SG11202110137VA SG11202110137VA SG11202110137VA SG11202110137VA SG 11202110137V A SG11202110137V A SG 11202110137VA SG 11202110137V A SG11202110137V A SG 11202110137VA SG 11202110137V A SG11202110137V A SG 11202110137VA SG 11202110137V A SG11202110137V A SG 11202110137VA
Authority
SG
Singapore
Prior art keywords
benzodiazepine derivatives
rsv inhibitors
rsv
inhibitors
benzodiazepine
Prior art date
Application number
SG11202110137VA
Inventor
Kaicheng Zhu
Kevin Mcgrath
Solymar Negretti-Emmanuelli
Adam Szymaniak
Jianming Yu
In Kim
Yat OR
Original Assignee
Enanta Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enanta Pharm Inc filed Critical Enanta Pharm Inc
Publication of SG11202110137VA publication Critical patent/SG11202110137VA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202110137VA 2019-03-18 2020-03-17 Benzodiazepine derivatives as rsv inhibitors SG11202110137VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962819915P 2019-03-18 2019-03-18
US201962821094P 2019-03-20 2019-03-20
PCT/US2020/023135 WO2020190935A1 (en) 2019-03-18 2020-03-17 Benzodiazepine derivatives as rsv inhibitors

Publications (1)

Publication Number Publication Date
SG11202110137VA true SG11202110137VA (en) 2021-10-28

Family

ID=72514103

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202110137VA SG11202110137VA (en) 2019-03-18 2020-03-17 Benzodiazepine derivatives as rsv inhibitors

Country Status (14)

Country Link
US (3) US11254664B2 (en)
EP (1) EP3941525A4 (en)
JP (1) JP7558189B2 (en)
CN (1) CN113710276B (en)
AU (1) AU2020240024B2 (en)
BR (1) BR112021018335A2 (en)
CA (1) CA3133300A1 (en)
IL (1) IL286363B2 (en)
MX (1) MX2021011144A (en)
PH (1) PH12021552201A1 (en)
SG (1) SG11202110137VA (en)
TW (1) TWI872055B (en)
UY (1) UY38614A (en)
WO (1) WO2020190935A1 (en)

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Also Published As

Publication number Publication date
EP3941525A1 (en) 2022-01-26
IL286363B1 (en) 2025-10-01
WO2020190935A1 (en) 2020-09-24
CN113710276B (en) 2024-03-29
TWI872055B (en) 2025-02-11
UY38614A (en) 2020-10-30
US20200299286A1 (en) 2020-09-24
IL286363B2 (en) 2026-02-01
US11912695B2 (en) 2024-02-27
US11254664B2 (en) 2022-02-22
US20220227746A1 (en) 2022-07-21
AU2020240024B2 (en) 2025-06-26
IL286363A (en) 2021-10-31
JP2022525893A (en) 2022-05-20
JP7558189B2 (en) 2024-09-30
AU2020240024A1 (en) 2021-10-14
EP3941525A4 (en) 2022-12-07
PH12021552201A1 (en) 2022-05-30
CA3133300A1 (en) 2020-09-24
KR20210138684A (en) 2021-11-19
US20240360117A1 (en) 2024-10-31
BR112021018335A2 (en) 2021-11-23
TW202102493A (en) 2021-01-16
MX2021011144A (en) 2022-01-18
CN113710276A (en) 2021-11-26

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