SG11202007977RA - Ophthalmic composition comprising diquafosol and cationic polymer - Google Patents
Ophthalmic composition comprising diquafosol and cationic polymerInfo
- Publication number
- SG11202007977RA SG11202007977RA SG11202007977RA SG11202007977RA SG11202007977RA SG 11202007977R A SG11202007977R A SG 11202007977RA SG 11202007977R A SG11202007977R A SG 11202007977RA SG 11202007977R A SG11202007977R A SG 11202007977RA SG 11202007977R A SG11202007977R A SG 11202007977RA
- Authority
- SG
- Singapore
- Prior art keywords
- diquafosol
- cationic polymer
- ophthalmic composition
- ophthalmic
- composition
- Prior art date
Links
- NMLMACJWHPHKGR-NCOIDOBVSA-N P(1),P(4)-bis(uridin-5'-yl) tetraphosphate Chemical compound N1([C@@H]2O[C@@H]([C@H]([C@H]2O)O)COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N2C(NC(=O)C=C2)=O)O)O)C=CC(=O)NC1=O NMLMACJWHPHKGR-NCOIDOBVSA-N 0.000 title 1
- 229920006317 cationic polymer Polymers 0.000 title 1
- 229950003529 diquafosol Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2018035578 | 2018-02-28 | ||
PCT/JP2019/007542 WO2019168023A1 (en) | 2018-02-28 | 2019-02-27 | Ophthalmic composition comprising diquafosol and cationic polymer |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202007977RA true SG11202007977RA (en) | 2020-09-29 |
Family
ID=67806273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202007977RA SG11202007977RA (en) | 2018-02-28 | 2019-02-27 | Ophthalmic composition comprising diquafosol and cationic polymer |
Country Status (14)
Country | Link |
---|---|
US (1) | US20210000844A1 (en) |
EP (1) | EP3760207A4 (en) |
JP (4) | JP6716800B2 (en) |
KR (3) | KR20250053220A (en) |
CN (2) | CN111757742B (en) |
BR (1) | BR112020017661A2 (en) |
CA (1) | CA3091700A1 (en) |
EA (1) | EA202092030A1 (en) |
MX (2) | MX2020008925A (en) |
PH (1) | PH12020551313B1 (en) |
SG (1) | SG11202007977RA (en) |
TW (3) | TWI781296B (en) |
UA (1) | UA129517C2 (en) |
WO (1) | WO2019168023A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11202007977RA (en) | 2018-02-28 | 2020-09-29 | Santen Pharmaceutical Co Ltd | Ophthalmic composition comprising diquafosol and cationic polymer |
ES2994624T3 (en) * | 2019-02-27 | 2025-01-27 | Santen Pharmaceutical Co Ltd | Ophthalmic composition containing diquafosol or salt thereof, vinyl-based polymer and cellulose-based polymer |
WO2021039748A1 (en) * | 2019-08-27 | 2021-03-04 | 参天製薬株式会社 | Diquafosol or salt thereof, and aqueous ophthalmic composition containing polyvinylpyrrolidone |
KR102365008B1 (en) * | 2020-06-23 | 2022-02-23 | 주식회사태준제약 | Ophthalmic Composition Comprising Diquafosol |
JP7230169B2 (en) * | 2020-12-25 | 2023-02-28 | 参天製薬株式会社 | Aqueous ophthalmic solution containing diquafosol or its salt, silver salt and ionic tonicity agent |
CN113712910A (en) * | 2021-08-05 | 2021-11-30 | 广州市桐晖药业有限公司 | Eye drops and preparation method thereof |
KR102794468B1 (en) | 2022-04-04 | 2025-04-14 | 서울대학교산학협력단 | Compositions for inhibiting sweetness and methods for inhibiting sweetness in foods |
KR20250038935A (en) * | 2023-09-13 | 2025-03-20 | 루다큐어 주식회사 | Eye drop formulations in the form of an aqueous solution comprising 8-oxo-2'-deoxyguanosine or a pharmaceutically acceptable salt thereof |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01294620A (en) | 1988-05-19 | 1989-11-28 | Kissei Pharmaceut Co Ltd | Aqueous liquid preparation and production thereof |
US5358706A (en) * | 1992-09-30 | 1994-10-25 | Union Carbide Chemicals & Plastics Technology Corporation | Muco-adhesive polymers |
US5422116A (en) * | 1994-02-18 | 1995-06-06 | Ciba-Geigy Corporation | Liquid ophthalmic sustained release delivery system |
JP3155689B2 (en) * | 1995-08-10 | 2001-04-16 | 昭和薬品化工株式会社 | Anti-inflammatory eye drops |
US5900407A (en) | 1997-02-06 | 1999-05-04 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with uridine triphosphates and related compounds |
PT1012154E (en) | 1997-07-25 | 2004-08-31 | Inspire Pharmaceuticals Inc | METHOD FOR PREPARING THE METHOD FOR PREPARATION, AND THEIR UTILIZATIONS |
JP2001294620A (en) | 2000-04-11 | 2001-10-23 | Showa Denko Kk | Plastic lens material, method for producing the material, composition for plastic lens, plastic lens obtained by curing the composition, and method for producing the plastic lens |
WO2001091795A1 (en) * | 2000-05-30 | 2001-12-06 | Santen Pharmaceutical Co., Ltd. | Ectocornea extension promoters |
EP4176906A1 (en) * | 2005-02-14 | 2023-05-10 | Johnson & Johnson Vision Care, Inc. | A comfortable ophthalmic device and methods of its production |
JP4515960B2 (en) | 2005-05-19 | 2010-08-04 | 株式会社資生堂 | Hairdressing detergent and method for using the same |
KR100870104B1 (en) * | 2005-11-28 | 2008-11-26 | 주식회사 머젠스 | Composition Having Effect on Treatment and Prevention of Dry eye syndrome |
CA2702475A1 (en) * | 2007-10-12 | 2009-04-23 | Resolvyx Pharmaceuticals, Inc. | Compositions and methods for the treatment of ophthalmic conditions |
KR20100133980A (en) * | 2008-03-07 | 2010-12-22 | 썬 파마 어드밴스트 리서치 컴패니 리미티드 | Eye drops composition |
PH12013501305A1 (en) * | 2010-12-28 | 2013-08-28 | Santen Pharmaceutical Co Ltd | Ophthalmic solution comprising diquafosol, method for producing the same, and method for inhibiting formation of insoluble precipitate |
MX353874B (en) * | 2012-03-26 | 2018-02-01 | Santen Pharmaceutical Co Ltd | Diquafosol-containing eye drop. |
SI3139903T1 (en) * | 2014-05-07 | 2019-10-30 | Croma Pharma Ges M B H | Aqueous ophthalmic solution and method for treating dry eye syndrome |
CN106456791B (en) * | 2014-06-10 | 2021-08-10 | 日本乐敦制药株式会社 | Ophthalmic aqueous composition |
KR102330736B1 (en) * | 2014-12-25 | 2021-11-23 | 산텐 세이야꾸 가부시키가이샤 | Aqueous ophthalmic solution |
KR101587385B1 (en) * | 2015-07-29 | 2016-01-21 | 국제약품공업주식회사 | Non-irritating cyclosporin ophthalmic solution and convenient manufacturing process |
JP2017043607A (en) * | 2015-08-24 | 2017-03-02 | 参天製薬株式会社 | Ophthalmologic film formulation |
DK3266446T3 (en) * | 2016-07-07 | 2019-02-11 | Salvat Lab Sa | Eye preparation comprising castor oil and medium chain triglyceride |
CN106772747B (en) * | 2016-12-26 | 2022-10-18 | 深圳市光科全息技术有限公司 | Optical film and manufacturing method thereof |
MY196565A (en) * | 2017-04-25 | 2023-04-19 | Wakamoto Pharma Co Ltd | Thermogelling Artificial Tears |
JP6582029B2 (en) * | 2017-10-03 | 2019-09-25 | 株式会社メニコン | Ophthalmic composition liquid and method of use thereof |
SG11202007977RA (en) | 2018-02-28 | 2020-09-29 | Santen Pharmaceutical Co Ltd | Ophthalmic composition comprising diquafosol and cationic polymer |
CN108853016A (en) * | 2018-09-26 | 2018-11-23 | 广州大光制药有限公司 | A kind of ophthalmic solution sodium eye drops and preparation method thereof |
ES2994624T3 (en) * | 2019-02-27 | 2025-01-27 | Santen Pharmaceutical Co Ltd | Ophthalmic composition containing diquafosol or salt thereof, vinyl-based polymer and cellulose-based polymer |
-
2019
- 2019-02-27 SG SG11202007977RA patent/SG11202007977RA/en unknown
- 2019-02-27 JP JP2020503563A patent/JP6716800B2/en active Active
- 2019-02-27 MX MX2020008925A patent/MX2020008925A/en unknown
- 2019-02-27 EA EA202092030A patent/EA202092030A1/en unknown
- 2019-02-27 TW TW108106730A patent/TWI781296B/en active
- 2019-02-27 CN CN201980015357.8A patent/CN111757742B/en active Active
- 2019-02-27 CA CA3091700A patent/CA3091700A1/en active Pending
- 2019-02-27 CN CN202311151214.4A patent/CN117137866A/en active Pending
- 2019-02-27 KR KR1020257011738A patent/KR20250053220A/en active Pending
- 2019-02-27 PH PH1/2020/551313A patent/PH12020551313B1/en unknown
- 2019-02-27 TW TW113102160A patent/TW202423451A/en unknown
- 2019-02-27 WO PCT/JP2019/007542 patent/WO2019168023A1/en active Application Filing
- 2019-02-27 TW TW111140996A patent/TWI833406B/en active
- 2019-02-27 UA UAA202006163A patent/UA129517C2/en unknown
- 2019-02-27 EP EP19759990.5A patent/EP3760207A4/en active Pending
- 2019-02-27 KR KR1020207027473A patent/KR102472773B1/en active Active
- 2019-02-27 KR KR1020227041383A patent/KR102796051B1/en active Active
- 2019-02-27 BR BR112020017661-3A patent/BR112020017661A2/en unknown
- 2019-02-27 US US16/976,504 patent/US20210000844A1/en not_active Abandoned
-
2020
- 2020-06-10 JP JP2020100953A patent/JP7297718B2/en active Active
- 2020-08-26 MX MX2022014791A patent/MX2022014791A/en unknown
-
2022
- 2022-07-21 JP JP2022116528A patent/JP7472202B2/en active Active
-
2024
- 2024-02-13 JP JP2024019332A patent/JP2024045506A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20210000844A1 (en) | 2021-01-07 |
TW202423451A (en) | 2024-06-16 |
JP2022136152A (en) | 2022-09-15 |
JP2024045506A (en) | 2024-04-02 |
PH12020551313B1 (en) | 2024-02-28 |
JP6716800B2 (en) | 2020-07-01 |
CN111757742B (en) | 2023-09-26 |
TWI781296B (en) | 2022-10-21 |
JPWO2019168023A1 (en) | 2020-05-28 |
CN111757742A (en) | 2020-10-09 |
EA202092030A1 (en) | 2020-11-16 |
MX2020008925A (en) | 2020-10-01 |
JP2020138980A (en) | 2020-09-03 |
PH12020551313A1 (en) | 2021-09-06 |
EP3760207A4 (en) | 2023-10-04 |
CA3091700A1 (en) | 2019-09-06 |
TW202000212A (en) | 2020-01-01 |
BR112020017661A2 (en) | 2020-12-22 |
MX2022014791A (en) | 2023-01-16 |
KR102796051B1 (en) | 2025-04-14 |
KR20250053220A (en) | 2025-04-21 |
CN117137866A (en) | 2023-12-01 |
JP7297718B2 (en) | 2023-06-26 |
JP7472202B2 (en) | 2024-04-22 |
TWI833406B (en) | 2024-02-21 |
TW202306572A (en) | 2023-02-16 |
WO2019168023A1 (en) | 2019-09-06 |
KR102472773B1 (en) | 2022-11-30 |
EP3760207A1 (en) | 2021-01-06 |
UA129517C2 (en) | 2025-05-21 |
KR20220163519A (en) | 2022-12-09 |
KR20200127002A (en) | 2020-11-09 |
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