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SG11202007977RA - Ophthalmic composition comprising diquafosol and cationic polymer - Google Patents

Ophthalmic composition comprising diquafosol and cationic polymer

Info

Publication number
SG11202007977RA
SG11202007977RA SG11202007977RA SG11202007977RA SG11202007977RA SG 11202007977R A SG11202007977R A SG 11202007977RA SG 11202007977R A SG11202007977R A SG 11202007977RA SG 11202007977R A SG11202007977R A SG 11202007977RA SG 11202007977R A SG11202007977R A SG 11202007977RA
Authority
SG
Singapore
Prior art keywords
diquafosol
cationic polymer
ophthalmic composition
ophthalmic
composition
Prior art date
Application number
SG11202007977RA
Inventor
Kyohei Takahashi
Hiroyuki Asada
Asuka Kamimura
Kenji Morishima
Yusuke Momokawa
Kenichi Endo
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of SG11202007977RA publication Critical patent/SG11202007977RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
SG11202007977RA 2018-02-28 2019-02-27 Ophthalmic composition comprising diquafosol and cationic polymer SG11202007977RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018035578 2018-02-28
PCT/JP2019/007542 WO2019168023A1 (en) 2018-02-28 2019-02-27 Ophthalmic composition comprising diquafosol and cationic polymer

Publications (1)

Publication Number Publication Date
SG11202007977RA true SG11202007977RA (en) 2020-09-29

Family

ID=67806273

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202007977RA SG11202007977RA (en) 2018-02-28 2019-02-27 Ophthalmic composition comprising diquafosol and cationic polymer

Country Status (14)

Country Link
US (1) US20210000844A1 (en)
EP (1) EP3760207A4 (en)
JP (4) JP6716800B2 (en)
KR (3) KR20250053220A (en)
CN (2) CN111757742B (en)
BR (1) BR112020017661A2 (en)
CA (1) CA3091700A1 (en)
EA (1) EA202092030A1 (en)
MX (2) MX2020008925A (en)
PH (1) PH12020551313B1 (en)
SG (1) SG11202007977RA (en)
TW (3) TWI781296B (en)
UA (1) UA129517C2 (en)
WO (1) WO2019168023A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202007977RA (en) 2018-02-28 2020-09-29 Santen Pharmaceutical Co Ltd Ophthalmic composition comprising diquafosol and cationic polymer
ES2994624T3 (en) * 2019-02-27 2025-01-27 Santen Pharmaceutical Co Ltd Ophthalmic composition containing diquafosol or salt thereof, vinyl-based polymer and cellulose-based polymer
WO2021039748A1 (en) * 2019-08-27 2021-03-04 参天製薬株式会社 Diquafosol or salt thereof, and aqueous ophthalmic composition containing polyvinylpyrrolidone
KR102365008B1 (en) * 2020-06-23 2022-02-23 주식회사태준제약 Ophthalmic Composition Comprising Diquafosol
JP7230169B2 (en) * 2020-12-25 2023-02-28 参天製薬株式会社 Aqueous ophthalmic solution containing diquafosol or its salt, silver salt and ionic tonicity agent
CN113712910A (en) * 2021-08-05 2021-11-30 广州市桐晖药业有限公司 Eye drops and preparation method thereof
KR102794468B1 (en) 2022-04-04 2025-04-14 서울대학교산학협력단 Compositions for inhibiting sweetness and methods for inhibiting sweetness in foods
KR20250038935A (en) * 2023-09-13 2025-03-20 루다큐어 주식회사 Eye drop formulations in the form of an aqueous solution comprising 8-oxo-2'-deoxyguanosine or a pharmaceutically acceptable salt thereof

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JPH01294620A (en) 1988-05-19 1989-11-28 Kissei Pharmaceut Co Ltd Aqueous liquid preparation and production thereof
US5358706A (en) * 1992-09-30 1994-10-25 Union Carbide Chemicals & Plastics Technology Corporation Muco-adhesive polymers
US5422116A (en) * 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
JP3155689B2 (en) * 1995-08-10 2001-04-16 昭和薬品化工株式会社 Anti-inflammatory eye drops
US5900407A (en) 1997-02-06 1999-05-04 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with uridine triphosphates and related compounds
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JP2001294620A (en) 2000-04-11 2001-10-23 Showa Denko Kk Plastic lens material, method for producing the material, composition for plastic lens, plastic lens obtained by curing the composition, and method for producing the plastic lens
WO2001091795A1 (en) * 2000-05-30 2001-12-06 Santen Pharmaceutical Co., Ltd. Ectocornea extension promoters
EP4176906A1 (en) * 2005-02-14 2023-05-10 Johnson & Johnson Vision Care, Inc. A comfortable ophthalmic device and methods of its production
JP4515960B2 (en) 2005-05-19 2010-08-04 株式会社資生堂 Hairdressing detergent and method for using the same
KR100870104B1 (en) * 2005-11-28 2008-11-26 주식회사 머젠스 Composition Having Effect on Treatment and Prevention of Dry eye syndrome
CA2702475A1 (en) * 2007-10-12 2009-04-23 Resolvyx Pharmaceuticals, Inc. Compositions and methods for the treatment of ophthalmic conditions
KR20100133980A (en) * 2008-03-07 2010-12-22 썬 파마 어드밴스트 리서치 컴패니 리미티드 Eye drops composition
PH12013501305A1 (en) * 2010-12-28 2013-08-28 Santen Pharmaceutical Co Ltd Ophthalmic solution comprising diquafosol, method for producing the same, and method for inhibiting formation of insoluble precipitate
MX353874B (en) * 2012-03-26 2018-02-01 Santen Pharmaceutical Co Ltd Diquafosol-containing eye drop.
SI3139903T1 (en) * 2014-05-07 2019-10-30 Croma Pharma Ges M B H Aqueous ophthalmic solution and method for treating dry eye syndrome
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KR102330736B1 (en) * 2014-12-25 2021-11-23 산텐 세이야꾸 가부시키가이샤 Aqueous ophthalmic solution
KR101587385B1 (en) * 2015-07-29 2016-01-21 국제약품공업주식회사 Non-irritating cyclosporin ophthalmic solution and convenient manufacturing process
JP2017043607A (en) * 2015-08-24 2017-03-02 参天製薬株式会社 Ophthalmologic film formulation
DK3266446T3 (en) * 2016-07-07 2019-02-11 Salvat Lab Sa Eye preparation comprising castor oil and medium chain triglyceride
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SG11202007977RA (en) 2018-02-28 2020-09-29 Santen Pharmaceutical Co Ltd Ophthalmic composition comprising diquafosol and cationic polymer
CN108853016A (en) * 2018-09-26 2018-11-23 广州大光制药有限公司 A kind of ophthalmic solution sodium eye drops and preparation method thereof
ES2994624T3 (en) * 2019-02-27 2025-01-27 Santen Pharmaceutical Co Ltd Ophthalmic composition containing diquafosol or salt thereof, vinyl-based polymer and cellulose-based polymer

Also Published As

Publication number Publication date
US20210000844A1 (en) 2021-01-07
TW202423451A (en) 2024-06-16
JP2022136152A (en) 2022-09-15
JP2024045506A (en) 2024-04-02
PH12020551313B1 (en) 2024-02-28
JP6716800B2 (en) 2020-07-01
CN111757742B (en) 2023-09-26
TWI781296B (en) 2022-10-21
JPWO2019168023A1 (en) 2020-05-28
CN111757742A (en) 2020-10-09
EA202092030A1 (en) 2020-11-16
MX2020008925A (en) 2020-10-01
JP2020138980A (en) 2020-09-03
PH12020551313A1 (en) 2021-09-06
EP3760207A4 (en) 2023-10-04
CA3091700A1 (en) 2019-09-06
TW202000212A (en) 2020-01-01
BR112020017661A2 (en) 2020-12-22
MX2022014791A (en) 2023-01-16
KR102796051B1 (en) 2025-04-14
KR20250053220A (en) 2025-04-21
CN117137866A (en) 2023-12-01
JP7297718B2 (en) 2023-06-26
JP7472202B2 (en) 2024-04-22
TWI833406B (en) 2024-02-21
TW202306572A (en) 2023-02-16
WO2019168023A1 (en) 2019-09-06
KR102472773B1 (en) 2022-11-30
EP3760207A1 (en) 2021-01-06
UA129517C2 (en) 2025-05-21
KR20220163519A (en) 2022-12-09
KR20200127002A (en) 2020-11-09

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