SG11202005952TA - Process for providing pegylated protein composition - Google Patents
Process for providing pegylated protein compositionInfo
- Publication number
- SG11202005952TA SG11202005952TA SG11202005952TA SG11202005952TA SG11202005952TA SG 11202005952T A SG11202005952T A SG 11202005952TA SG 11202005952T A SG11202005952T A SG 11202005952TA SG 11202005952T A SG11202005952T A SG 11202005952TA SG 11202005952T A SG11202005952T A SG 11202005952TA
- Authority
- SG
- Singapore
- Prior art keywords
- protein composition
- pegylated protein
- providing
- providing pegylated
- composition
- Prior art date
Links
- 108091006006 PEGylated Proteins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17211122 | 2017-12-29 | ||
PCT/EP2018/097125 WO2019129878A1 (en) | 2017-12-29 | 2018-12-28 | Process for providing pegylated protein composition |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202005952TA true SG11202005952TA (en) | 2020-07-29 |
Family
ID=60856965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202005952TA SG11202005952TA (en) | 2017-12-29 | 2018-12-28 | Process for providing pegylated protein composition |
Country Status (11)
Country | Link |
---|---|
US (1) | US20200362002A1 (en) |
EP (1) | EP3731873B1 (en) |
JP (2) | JP7227633B2 (en) |
KR (1) | KR102497097B1 (en) |
CN (1) | CN111727063A (en) |
ES (1) | ES2909454T3 (en) |
HR (1) | HRP20220388T1 (en) |
PL (1) | PL3731873T3 (en) |
SG (1) | SG11202005952TA (en) |
SI (1) | SI3731873T1 (en) |
WO (1) | WO2019129878A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US12208142B2 (en) * | 2017-12-29 | 2025-01-28 | Hoffmann-La Roche Inc. | Process for providing PEGylated protein composition |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2646438B1 (en) | 1989-03-20 | 2007-11-02 | Pasteur Institut | A METHOD FOR SPECIFIC REPLACEMENT OF A COPY OF A GENE PRESENT IN THE RECEIVER GENOME BY INTEGRATION OF A GENE DIFFERENT FROM THAT OR INTEGRATION |
ES2090297T5 (en) | 1989-11-06 | 2005-03-01 | Cell Genesys, Inc. | PRODUCTION OF PROTEINS THAT USE HOMOLOGICAL RECOMBINATION. |
DE69031172T2 (en) | 1989-12-22 | 1998-03-12 | Applied Research Systems Ars Holding N.V., Curacao | MODIFICATION OF ENDOGENIC GENE EXPRESSION BY MEANS OF A REGULATORY ELEMENT BY MEANS OF HOMOLOGOUS RECOMBINATION |
JP3051145B2 (en) | 1990-08-28 | 2000-06-12 | 住友製薬株式会社 | Novel polyethylene glycol derivative modified peptide |
US5641670A (en) | 1991-11-05 | 1997-06-24 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
US5968502A (en) | 1991-11-05 | 1999-10-19 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
PT101031B (en) | 1991-11-05 | 2002-07-31 | Transkaryotic Therapies Inc | PROCESS FOR THE SUPPLY OF PROTEINS BY GENETIC THERAPY |
WO1994001451A2 (en) | 1992-07-13 | 1994-01-20 | Bionebraska, Inc. | Method for modification of recombinant polypeptides |
TW402639B (en) | 1992-12-03 | 2000-08-21 | Transkaryotic Therapies Inc | Protein production and protein delivery |
US5932462A (en) | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
MXPA01007609A (en) | 1999-01-29 | 2003-06-24 | Hoffmann La Roche | Gcsf conjugates. |
CZ299516B6 (en) | 1999-07-02 | 2008-08-20 | F. Hoffmann-La Roche Ag | Erythropoietin glycoprotein conjugate, process for its preparation and use and pharmaceutical composition containing thereof |
JO2291B1 (en) * | 1999-07-02 | 2005-09-12 | اف . هوفمان لاروش ايه جي | Erythopintin derivatives |
RS51292B (en) * | 2000-05-15 | 2010-12-31 | F. Hoffmann-La Roche Ag. | NEW PHARMACEUTICAL MIXTURE |
AU2003301122B2 (en) * | 2002-12-19 | 2009-11-26 | Nektar Therapeutics | Cyanovirin variant-polymer conjugates |
CN101010105A (en) * | 2004-08-31 | 2007-08-01 | 法玛西雅厄普约翰有限责任公司 | Glycerol branched polyethylene glycol human growth hormone conjugates, process for their preparation, and methods of use thereof |
WO2007010552A2 (en) * | 2005-03-17 | 2007-01-25 | Serum Institute Of India Limited | N- terminal peg conjugate of erythropoietin |
US8969532B2 (en) * | 2006-10-03 | 2015-03-03 | Novo Nordisk A/S | Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography |
AR067537A1 (en) * | 2007-07-17 | 2009-10-14 | Hoffmann La Roche | PURIFIED POLYPEPTIDES PURIFICATION |
CN102639553A (en) * | 2009-11-24 | 2012-08-15 | 诺沃—诺迪斯克保健股份有限公司 | Method of purifying pegylated proteins |
KR20120118065A (en) * | 2010-02-12 | 2012-10-25 | 디에스엠 아이피 어셋츠 비.브이. | Single unit antibody purification |
CN102234310B (en) * | 2010-04-30 | 2017-02-08 | 杭州九源基因工程有限公司 | Polyethylene glycol modified protein separating and purifying method |
KR101578586B1 (en) * | 2010-09-14 | 2015-12-17 | 에프. 호프만-라 로슈 아게 | Method for purifying pegylated erythropoietin |
CN102453087B (en) * | 2010-10-22 | 2013-12-25 | 广东赛保尔生物医药技术有限公司 | Purification and preparation method of mono-substituted PEG-EPO |
SG11202006140TA (en) * | 2017-12-29 | 2020-07-29 | Hoffmann La Roche | Process for providing pegylated protein composition |
-
2018
- 2018-12-28 SI SI201830617T patent/SI3731873T1/en unknown
- 2018-12-28 US US16/958,114 patent/US20200362002A1/en active Pending
- 2018-12-28 CN CN201880089659.5A patent/CN111727063A/en active Pending
- 2018-12-28 SG SG11202005952TA patent/SG11202005952TA/en unknown
- 2018-12-28 KR KR1020207021891A patent/KR102497097B1/en active Active
- 2018-12-28 JP JP2020536096A patent/JP7227633B2/en active Active
- 2018-12-28 PL PL18830893T patent/PL3731873T3/en unknown
- 2018-12-28 ES ES18830893T patent/ES2909454T3/en active Active
- 2018-12-28 HR HRP20220388TT patent/HRP20220388T1/en unknown
- 2018-12-28 WO PCT/EP2018/097125 patent/WO2019129878A1/en unknown
- 2018-12-28 EP EP18830893.6A patent/EP3731873B1/en active Active
-
2023
- 2023-02-03 JP JP2023014951A patent/JP2023055876A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
KR102497097B1 (en) | 2023-02-06 |
SI3731873T1 (en) | 2022-05-31 |
JP2023055876A (en) | 2023-04-18 |
JP7227633B2 (en) | 2023-02-22 |
ES2909454T3 (en) | 2022-05-06 |
US20200362002A1 (en) | 2020-11-19 |
JP2021508706A (en) | 2021-03-11 |
KR20200104382A (en) | 2020-09-03 |
EP3731873A1 (en) | 2020-11-04 |
EP3731873B1 (en) | 2022-01-26 |
HRP20220388T1 (en) | 2022-05-27 |
CN111727063A (en) | 2020-09-29 |
WO2019129878A1 (en) | 2019-07-04 |
PL3731873T3 (en) | 2022-04-25 |
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