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SG11202003178PA - Btk inhibitor compounds - Google Patents

Btk inhibitor compounds

Info

Publication number
SG11202003178PA
SG11202003178PA SG11202003178PA SG11202003178PA SG11202003178PA SG 11202003178P A SG11202003178P A SG 11202003178PA SG 11202003178P A SG11202003178P A SG 11202003178PA SG 11202003178P A SG11202003178P A SG 11202003178PA SG 11202003178P A SG11202003178P A SG 11202003178PA
Authority
SG
Singapore
Prior art keywords
btk inhibitor
inhibitor compounds
compounds
btk
inhibitor
Prior art date
Application number
SG11202003178PA
Other languages
English (en)
Inventor
Kenneth James Henry
Albert Khilevich
Steven Kuklish
Katherine Partridge
Steven Quimby
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SG11202003178PA publication Critical patent/SG11202003178PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11202003178PA 2017-11-06 2018-10-30 Btk inhibitor compounds SG11202003178PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762581967P 2017-11-06 2017-11-06
PCT/US2018/058104 WO2019089512A1 (fr) 2017-11-06 2018-10-30 Composés inhibiteurs de btk

Publications (1)

Publication Number Publication Date
SG11202003178PA true SG11202003178PA (en) 2020-05-28

Family

ID=64277913

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202003178PA SG11202003178PA (en) 2017-11-06 2018-10-30 Btk inhibitor compounds

Country Status (35)

Country Link
US (1) US11542249B2 (fr)
EP (1) EP3707133B1 (fr)
JP (1) JP6920553B2 (fr)
KR (1) KR102410202B1 (fr)
CN (1) CN111278818B (fr)
AR (1) AR113796A1 (fr)
AU (1) AU2018360478B2 (fr)
BR (1) BR112020006749A2 (fr)
CA (1) CA3080123C (fr)
CL (1) CL2020001089A1 (fr)
CR (1) CR20200183A (fr)
CY (1) CY1124994T1 (fr)
DK (1) DK3707133T3 (fr)
DO (1) DOP2020000103A (fr)
EA (1) EA039398B1 (fr)
EC (1) ECSP20024395A (fr)
ES (1) ES2904843T3 (fr)
HR (1) HRP20220178T1 (fr)
HU (1) HUE057987T2 (fr)
IL (1) IL273778B (fr)
JO (1) JOP20200104A1 (fr)
LT (1) LT3707133T (fr)
MA (1) MA50561B1 (fr)
MD (1) MD3707133T2 (fr)
MX (1) MX394259B (fr)
PE (1) PE20201168A1 (fr)
PH (1) PH12020550791B1 (fr)
PL (1) PL3707133T3 (fr)
PT (1) PT3707133T (fr)
RS (1) RS62805B1 (fr)
SG (1) SG11202003178PA (fr)
SI (1) SI3707133T1 (fr)
TW (1) TWI694995B (fr)
UA (1) UA126079C2 (fr)
WO (1) WO2019089512A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022533968A (ja) * 2019-05-23 2022-07-27 ノバルティス アーゲー ブルトン型チロシンキナーゼ阻害剤を使用したシェーグレン症候群を処置する方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2205564B1 (fr) * 2007-10-23 2014-07-30 F. Hoffmann-La Roche AG Nouveaux inhibiteurs de kinase
WO2011140488A1 (fr) * 2010-05-07 2011-11-10 Gilead Connecticut, Inc. Composés de pyridone et d'aza-pyridone et leurs procédés d'utilisation
AR082590A1 (es) * 2010-08-12 2012-12-19 Hoffmann La Roche Inhibidores de la tirosina-quinasa de bruton
BR112013030442B1 (pt) * 2011-06-10 2021-11-09 Merck Patent Gmbh Compostos de pirimidina e piridina com atividade inibidora de btk, seus usos, composição, e kit
WO2014093230A2 (fr) * 2012-12-10 2014-06-19 Merck Patent Gmbh Compositions et procédés de fabrication de composés pyrimidine et pyridine ayant une activité inhibitrice de btk
GB2516303A (en) * 2013-07-18 2015-01-21 Redx Pharma Ltd Compounds
US9512084B2 (en) * 2013-11-29 2016-12-06 Novartis Ag Amino pyrimidine derivatives
WO2017059280A1 (fr) 2015-10-02 2017-04-06 The University Of North Carolina At Chapel Hill Nouveaux inhibiteurs de pan-tam et doubles inhibiteurs de mer/axl

Also Published As

Publication number Publication date
TW201930293A (zh) 2019-08-01
IL273778A (en) 2020-05-31
MD3707133T2 (ro) 2022-07-31
CA3080123A1 (fr) 2019-05-09
WO2019089512A1 (fr) 2019-05-09
TWI694995B (zh) 2020-06-01
PH12020550791A1 (en) 2021-04-12
MX394259B (es) 2025-03-24
US20200290997A1 (en) 2020-09-17
PT3707133T (pt) 2022-01-27
DOP2020000103A (es) 2020-09-15
CN111278818A (zh) 2020-06-12
EA202090843A1 (ru) 2020-07-24
JP6920553B2 (ja) 2021-08-18
CR20200183A (es) 2020-05-30
AR113796A1 (es) 2020-06-10
MX2020004435A (es) 2020-08-06
EP3707133A1 (fr) 2020-09-16
HUE057987T2 (hu) 2022-06-28
JOP20200104A1 (ar) 2022-10-30
CA3080123C (fr) 2021-11-09
NZ764452A (en) 2023-09-29
DK3707133T3 (da) 2022-01-03
MA50561A (fr) 2020-09-16
EA039398B1 (ru) 2022-01-24
AU2018360478A1 (en) 2020-04-23
BR112020006749A2 (pt) 2020-10-06
AU2018360478B2 (en) 2020-09-17
HRP20220178T1 (hr) 2022-04-29
MA50561B1 (fr) 2022-03-31
KR102410202B1 (ko) 2022-06-22
RS62805B1 (sr) 2022-02-28
LT3707133T (lt) 2022-01-25
ECSP20024395A (es) 2020-06-30
PL3707133T3 (pl) 2022-04-04
CL2020001089A1 (es) 2020-10-23
PH12020550791B1 (en) 2024-04-17
JP2021501749A (ja) 2021-01-21
IL273778B (en) 2022-06-01
PE20201168A1 (es) 2020-10-28
ES2904843T3 (es) 2022-04-06
CN111278818B (zh) 2023-03-28
KR20200060480A (ko) 2020-05-29
US11542249B2 (en) 2023-01-03
UA126079C2 (uk) 2022-08-10
CY1124994T1 (el) 2023-01-05
SI3707133T1 (sl) 2022-02-28
EP3707133B1 (fr) 2021-12-15

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